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Current Insights on the Use of Insulin and the Potential Use of Insulin Mimetics in Targeting Insulin Signalling in Alzheimer's Disease.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15811, doi. 10.3390/ijms232415811
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- Article
Butyrate Lowers Cellular Cholesterol through HDAC Inhibition and Impaired SREBP-2 Signalling.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15506, doi. 10.3390/ijms232415506
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- Article
The HDAC Inhibitor Butyrate Impairs β Cell Function and Activates the Disallowed Gene Hexokinase I.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 24, p. 13330, doi. 10.3390/ijms222413330
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- Article
The Immunometabolic Roles of Various Fatty Acids in Macrophages and Lymphocytes.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 16, p. 8460, doi. 10.3390/ijms22168460
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- Publication type:
- Article
Are Heat Shock Proteins an Important Link between Type 2 Diabetes and Alzheimer Disease?
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- International Journal of Molecular Sciences, 2020, v. 21, n. 21, p. 8204, doi. 10.3390/ijms21218204
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- Article
Molecular mechanisms of ROS production and oxidative stress in diabetes.
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- Biochemical Journal, 2016, v. 473, n. 24, p. 4527, doi. 10.1042/BCJ20160503C
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- Publication type:
- Article
Regulatory principles in metabolism – then and now.
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- Biochemical Journal, 2016, v. 473, n. 13, p. 1845, doi. 10.1042/BCJ20160103
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- Article
Bscl2 Deficiency Does Not Directly Impair the Innate Immune Response in a Murine Model of Generalized Lipodystrophy.
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- Journal of Clinical Medicine, 2021, v. 10, n. 3, p. 441, doi. 10.3390/jcm10030441
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- Publication type:
- Article
Effects of high EPA and high DHA fish oils on changes in signaling associated with protein metabolism induced by hindlimb suspension in rats.
- Published in:
- Physiological Reports, 2016, v. 4, n. 18, p. n/a, doi. 10.14814/phy2.12958
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- Publication type:
- Article
Inflammation and Oxidative Stress: The Molecular Connectivity between Insulin Resistance, Obesity, and Alzheimer’s Disease.
- Published in:
- Mediators of Inflammation, 2015, v. 2015, p. 1, doi. 10.1155/2015/105828
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- Publication type:
- Article
The Chaperone Balance Hypothesis: The Importance of the Extracellular to Intracellular HSP70 Ratio to Inflammation-Driven Type 2 Diabetes, the Effect of Exercise, and the Implications for Clinical Management.
- Published in:
- Mediators of Inflammation, 2015, v. 2015, p. 1, doi. 10.1155/2015/249205
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- Publication type:
- Article
Persistence of Inflammatory Response to Intense Exercise in Diabetic Rats.
- Published in:
- Experimental Diabetes Research, 2012, p. 1, doi. 10.1155/2012/213986
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- Publication type:
- Article
INSULIN RESISTANCE IS ASSOCIATED WITH REDUCTIONS IN SPECIFIC COGNITIVE DOMAINS AND INCREASES IN CSF TAU IN COGNITIVELY NORMAL ADULTS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1308, doi. 10.1016/j.jalz.2017.06.2000
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- Article
Epigenetic effects of metformin: From molecular mechanisms to clinical implications.
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- Diabetes, Obesity & Metabolism, 2018, v. 20, n. 7, p. 1553, doi. 10.1111/dom.13262
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- Publication type:
- Article
Inducible nitric oxide synthase inhibitor 1400W increases Na<sup>+</sup>,K<sup>+</sup>‐ATPase levels and activity and ameliorates mitochondrial dysfunction in Ctns null kidney proximal tubular epithelial cells.
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- Clinical & Experimental Pharmacology & Physiology, 2018, v. 45, n. 11, p. 1149, doi. 10.1111/1440-1681.12998
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- Publication type:
- Article
The Impact of Vitamin D Levels on Inflammatory Status: A Systematic Review of Immune Cell Studies.
- Published in:
- PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141770
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- Publication type:
- Article
Wnt Antagonist Secreted Frizzled-Related Protein 4 Upregulates Adipogenic Differentiation in Human Adipose Tissue-Derived Mesenchymal Stem Cells.
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- PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0118005
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- Publication type:
- Article
Oleic, Linoleic and Linolenic Acids Increase ROS Production by Fibroblasts via NADPH Oxidase Activation.
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- PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0058626
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- Publication type:
- Article
Mathematical Model of Metabolism and Electrophysiology of Amino Acid and Glucose Stimulated Insulin Secretion: <i>In Vitro</i> Validation Using a β-Cell Line.
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- PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0052611
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- Publication type:
- Article
Cancer stem cell metabolism: a potential target for cancer therapy.
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- Molecular Cancer, 2016, v. 15, p. 1, doi. 10.1186/s12943-016-0555-x
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- Publication type:
- Article
Effect of Walking and Running on the Cardiorespiratory System, Muscle Injury, and the Antioxidant System after 30 Min at the Walk-Run Transition Speed.
- Published in:
- Journal of Exercise Physiology Online, 2012, v. 15, n. 5, p. 40
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- Publication type:
- Article
Statins Do Not Directly Inhibit the Activity of Major Epigenetic Modifying Enzymes.
- Published in:
- Cancers, 2019, v. 11, n. 4, p. 516, doi. 10.3390/cancers11040516
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- Publication type:
- Article
Regulation of Cancer Stem Cell Metabolism by Secreted Frizzled-Related Protein 4 (sFRP4).
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- Cancers, 2018, v. 10, n. 2, p. 40, doi. 10.3390/cancers10020040
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- Publication type:
- Article
Effects of pharmacological inhibition of NADPH oxidase or iNOS on pro-inflammatory cytokine, palmitic acid or H<sub>2</sub>O<sub>2</sub>-induced mouse islet or clonal pancreatic β-cell dysfunction.
- Published in:
- Bioscience Reports, 2010, v. 30, n. 6, p. 445, doi. 10.1042/BSR20090138
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- Publication type:
- Article
The regulatory roles of NADPH oxidase, intra- and extra-cellular HSP70 in pancreatic islet function, dysfunction and diabetes.
- Published in:
- Clinical Science, 2015, v. 128, n. 11, p. 789, doi. 10.1042/CS20140695
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- Article
The impact of cryopreservation on human peripheral blood leucocyte bioenergetics.
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- Clinical Science, 2015, v. 128, n. 10, p. 723, doi. 10.1042/CS20140725
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- Publication type:
- Article
Elevated levels of extracellular heat-shock protein 72 (eHSP72) are positively correlated with insulin resistance in vivo and cause pancreatic β-cell dysfunction and death in vitro.
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- Clinical Science, 2014, v. 126, n. 10, p. 739, doi. 10.1042/CS20130678
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- Publication type:
- Article
Angiotensin-Converting Enzyme Related-Polymorphisms on Inflammation, Muscle and Myocardial Damage After a Marathon Race.
- Published in:
- Frontiers in Genetics, 2019, p. 1, doi. 10.3389/fgene.2019.00984
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- Publication type:
- Article
The effect of cigarette smoking, alcohol consumption and fruit and vegetable consumption on IVF outcomes: a review and presentation of original data.
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- Reproductive Biology & Endocrinology, 2015, v. 13, p. 1, doi. 10.1186/s12958-015-0133-x
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- Publication type:
- Article
Investigation of the effects of sulfonylurea exposure on pancreatic beta cell metabolism.
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- FEBS Journal, 2006, v. 273, n. 22, p. 5160, doi. 10.1111/j.1742-4658.2006.05513.x
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- Publication type:
- Article
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.
- Published in:
- Nature Immunology, 2010, v. 11, n. 10, p. 897, doi. 10.1038/ni.1935
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- Publication type:
- Article
Effects of EPA and DHA on proliferation, cytokine production, and gene expression in Raji cells.
- Published in:
- Lipids, 2004, v. 39, n. 9, p. 857, doi. 10.1007/s11745-004-1307-2
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- Article
Genes regulated by arachidonic and oleic acids in Raji cells.
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- Lipids, 2003, v. 38, n. 11, p. 1157, doi. 10.1007/s11745-003-1174-x
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- Article
The Role of Cystinosin in the Intermediary Thiol Metabolism and Redox Homeostasis in Kidney Proximal Tubular Cells.
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- Antioxidants, 2018, v. 7, n. 12, p. 179, doi. 10.3390/antiox7120179
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- Article
Amylin and beta amyloid proteins interact to form amorphous heterocomplexes with enhanced toxicity in neuronal cells.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-66602-9
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- Article
Pleiotropic Effects of GLP-1 and Analogs on Cell Signaling, Metabolism, and Function.
- Published in:
- Frontiers in Endocrinology, 2018, p. N.PAG, doi. 10.3389/fendo.2018.00672
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- Publication type:
- Article
Novel dehydroepiandrosterone troche supplementation improves the serum androgen profile of women undergoing in vitro fertilization.
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- Drug Design, Development & Therapy, 2015, v. 9, p. 5569, doi. 10.2147/DDDT.S92467
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- Publication type:
- Article
Overview: metabolomics and lipidomics in nutrition and metabolism research.
- Published in:
- Essays in Biochemistry, 2016, v. 60, n. 5, p. 407, doi. 10.1042/EBC20160047
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- Publication type:
- Article
Amino Acid Metabolism, β-Cell Function, and Diabetes.
- Published in:
- Diabetes, 2006, v. 55, p. S39, doi. 10.2337/db06-S006
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- Publication type:
- Article
A nuclear magnetic resonance-based demonstration of substantial oxidative L-alanine metabolism and L-alanine-enhanced glucose metabolism in a clonal pancreatic beta-cell line: metabolism of L-alanine is important to the regulation of insulin secretion.
- Published in:
- 2002
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- Publication type:
- journal article
Activation of survival and apoptotic signaling pathways in lymphocytes exposed to palmitic acid.
- Published in:
- Journal of Cellular Physiology, 2012, v. 227, n. 1, p. 339, doi. 10.1002/jcp.22740
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- Publication type:
- Article
The effects of aerobic exercise training at two different intensities in obesity and type 2 diabetes: implications for oxidative stress, low-grade inflammation and nitric oxide production.
- Published in:
- 2014
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- Publication type:
- journal article
The effects of aerobic exercise training at two different intensities in obesity and type 2 diabetes: implications for oxidative stress, low-grade inflammation and nitric oxide production.
- Published in:
- European Journal of Applied Physiology, 2014, v. 114, n. 2, p. 251, doi. 10.1007/s00421-013-2769-6
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- Publication type:
- Article
The Critical Role of Cell Metabolism for Essential Neutrophil Functions.
- Published in:
- Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2020, v. 54, n. 4, p. 629, doi. 10.33594/000000245
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- Publication type:
- Article
Lysosomal cystine accumulation promotes mitochondrial depolarization and induction of redox-sensitive genes in human kidney proximal tubular cells.
- Published in:
- Journal of Physiology, 2016, v. 594, n. 12, p. 3353, doi. 10.1113/JP271858
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- Publication type:
- Article
Cystine accumulation attenuates insulin release from the pancreatic β-cell due to elevated oxidative stress and decreased ATP levels.
- Published in:
- Journal of Physiology, 2015, v. 593, n. 23, p. 5167, doi. 10.1113/JP271237
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- Publication type:
- Article
Elevated levels of branched-chain amino acids have little effect on pancreatic islet cells, but l-arginine impairs function through activation of the endoplasmic reticulum stress response.
- Published in:
- Experimental Physiology, 2014, v. 99, n. 3, p. 538, doi. 10.1113/expphysiol.2013.077495
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- Publication type:
- Article
Cystine dimethylester loading promotes oxidative stress and a reduction in ATP independent of lysosomal cystine accumulation in a human proximal tubular epithelial cell line.
- Published in:
- Experimental Physiology, 2013, v. 98, n. 10, p. 1505, doi. 10.1113/expphysiol.2013.073809
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- Publication type:
- Article
Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism.
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- Microbiome, 2017, v. 5, p. 1, doi. 10.1186/s40168-017-0312-4
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- Publication type:
- Article
Cellular and metabolic mechanisms of nutrient actions in immune function.
- Published in:
- Nutrition & Diabetes, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41387-021-00162-3
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- Publication type:
- Article