Found: 21
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Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach.
- Published in:
- Chemical Biology & Drug Design, 2015, v. 86, n. 2, p. 180, doi. 10.1111/cbdd.12474
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- Article
Population pharmacokinetics of carboplatin in children<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 1996, v. 59, n. 4, p. 436, doi. 10.1016/S0009-9236(96)90113-7
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- Publication type:
- Article
PARP inhibitor rucaparib induces changes in NAD levels in cells and liver tissues as assessed by MRS.
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- NMR in Biomedicine, 2017, v. 30, n. 9, p. n/a, doi. 10.1002/nbm.3736
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- Article
Synthesis and biological properties of 3-methyl-10-propargyl-5,8-dideazafolic acid.
- Published in:
- Journal of Heterocyclic Chemistry, 1989, v. 26, n. 5, p. 1501, doi. 10.1002/jhet.5570260548
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- Article
Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.
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- 2004
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- Publication type:
- journal article
2-[11C]thymidine positron emission tomography as an indicator of thymidylate synthase inhibition in patients treated with AG337.
- Published in:
- 2003
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- Publication type:
- journal article
2-[[sup 11]C]Thymidine Positron Emission Tomography as an Indicator of Thymidylate Synthase Inhibition in Patients Treated With AG337.
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- JNCI: Journal of the National Cancer Institute, 2003, v. 95, n. 9, p. 675, doi. 10.1093/jnci/95.9.675
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- Publication type:
- Article
In vivo and ex vivo magnetic resonance spectroscopy as applied to pharmacokinetic studies with anticancer agents: a review.
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- NMR in Biomedicine, 1992, v. 5, n. 5, p. 273, doi. 10.1002/nbm.1940050514
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- Publication type:
- Article
Synthesis and Activity of Putative Small-Molecule Inhibitors of the F-Box Protein SKP2.
- Published in:
- Australian Journal of Chemistry, 2015, v. 68, n. 4, p. 660, doi. 10.1071/CH14586
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- Publication type:
- Article
The Enhanced <i>In Vivo</i> Activity of the Combination of a MEK and a PI3K Inhibitor Correlates with [<sup>18</sup>F]-FLT PET in Human Colorectal Cancer Xenograft Tumour-Bearing Mice.
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- PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0081763
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- Article
Characterisation of a Tip60 Specific Inhibitor, NU9056, in Prostate Cancer.
- Published in:
- PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0045539
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- Publication type:
- Article
Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy.
- Published in:
- 2020
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- Publication type:
- journal article
Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy.
- Published in:
- Journal of Clinical Investigation, 2020, v. 130, n. 1, p. 258, doi. 10.1172/JCI127483
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- Publication type:
- Article
Randomized cross-over clinical trial to study potential pharmacokinetic interactions between cisplatin or carboplatin and etoposide.
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- British Journal of Clinical Pharmacology, 2002, v. 53, n. 1, p. 83, doi. 10.1046/j.0306-5251.2001.01513.x
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- Article
Compromised CDK1 activity sensitizes BRCA-proficient cancers to PARP inhibition.
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- Nature Medicine, 2011, v. 17, n. 7, p. 875, doi. 10.1038/nm.2377
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- Publication type:
- Article
Enhanced anti-tumour activity of the combination of the novel MEK inhibitor WX-554 and the novel PI3K inhibitor WX-037.
- Published in:
- 2016
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- Publication type:
- journal article
An evaluation of thymidine phosphorylase as a means of preventing thymidine rescue from the thymidylate synthase inhibitor raltitrexed.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2007, v. 59, n. 2, p. 197, doi. 10.1007/s00280-006-0258-x
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- Publication type:
- Article
Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor.
- Published in:
- Nature Structural Biology, 2002, v. 9, n. 10, p. 745, doi. 10.1038/nsb842
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- Publication type:
- Article
Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma.
- Published in:
- International Journal of Cancer, 2019, v. 144, n. 12, p. 3146, doi. 10.1002/ijc.32058
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- Article
Sulfatase-2: a prognostic biomarker and candidate therapeutic target in patients with pancreatic ductal adenocarcinoma.
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- 2016
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- Publication type:
- journal article
Combined PI3K and CDK2 inhibition induces cell death and enhances in vivo antitumour activity in colorectal cancer.
- Published in:
- 2016
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- Publication type:
- journal article