Works by Nevalainen, Tapio

Results: 24

Aging-associated patterns in the expression of human endogenous retroviruses.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0207407

By:

Nevalainen, Tapio;
Autio, Arttu;
Mishra, Binisha Hamal;
Marttila, Saara;
Jylhä, Marja;
Hurme, Mikko

Publication type:

Article

Effect of aging on the transcriptomic changes associated with the expression of the HERV-K (HML-2) provirus at 1q22.

Published in:

Immunity & Ageing, 2020, v. 17, n. 1, p. 1, doi. 10.1186/s12979-020-00182-0

By:

Autio, Arttu;
Nevalainen, Tapio;
Mishra, Binisha H.;
Jylhä, Marja;
Flinck, Heini;
Hurme, Mikko

Publication type:

Article

CD27- IgD- B cell memory subset associates with inflammation and frailty in elderly individuals but only in males.

Published in:

Immunity & Ageing, 2019, v. 16, n. 1, p. N.PAG, doi. 10.1186/s12979-019-0159-6

By:

Nevalainen, Tapio;
Autio, Arttu;
Kummola, Laura;
Salomaa, Tanja;
Junttila, Ilkka;
Jylhä, Marja;
Hurme, Mikko

Publication type:

Article

Human endogenous retrovirus W in multiple sclerosis: transcriptional activity is associated with decline in oligodendrocyte proportions in the white matter of the brain.

Published in:

Journal of NeuroVirology, 2024, v. 30, n. 4, p. 393, doi. 10.1007/s13365-024-01208-9

By:

Nevalainen, Tapio;
Autio-Kimura, Arttu;
Hurme, Mikko

Publication type:

Article

Biochemical and Pharmacological Characterization of the Human Lymphocyte Antigen B-Associated Transcript 5 (BAT5/ABHD16A).

Published in:

PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0109869

By:

Savinainen, Juha R.;
Patel, Jayendra Z.;
Parkkari, Teija;
Navia-Paldanius, Dina;
Marjamaa, Joona J. T.;
Laitinen, Tuomo;
Nevalainen, Tapio;
Laitinen, Jarmo T.

Publication type:

Article

Discovery of Triterpenoids as Reversible Inhibitors of α/β-hydrolase Domain Containing 12 (ABHD12).

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0098286

By:

Parkkari, Teija;
Haavikko, Raisa;
Laitinen, Tuomo;
Navia-Paldanius, Dina;
Rytilahti, Roosa;
Vaara, Miia;
Lehtonen, Marko;
Alakurtti, Sami;
Yli-Kauhaluoma, Jari;
Nevalainen, Tapio;
Savinainen, Juha R.;
Laitinen, Jarmo T.

Publication type:

Article

Transcriptional Analysis Reveals Gender-Specific Changes in the Aging of the Human Immune System.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0066229

By:

Marttila, Saara;
Jylhävä, Juulia;
Nevalainen, Tapio;
Nykter, Matti;
Jylhä, Marja;
Hervonen, Antti;
Tserel, Liina;
Peterson, Pärt;
Hurme, Mikko

Publication type:

Article

Synthesis and In Vitro Evaluation of Novel 2-oxo-1,2-dihydroquinoline CB2 Receptor Inverse Agonists.

Published in:

2006

By:

Raitio, Katri H.;
Savinainen, Juha R.;
Nevalainen, Tapio;
Järvinen, Tomi;
Vepsäläinen, Jouko

Publication type:

Letter

Substituent effects of <sup>1</sup>H NMR parameters of chlorinated diphenyl ethers. A statistical approach.

Published in:

Magnetic Resonance in Chemistry, 1994, v. 32, n. 8, p. 480, doi. 10.1002/mrc.1260320809

By:

Nevalainen, Tapio;
Kolehmainen, Erkki

Publication type:

Article

<sup>13</sup>C NMR study of aromatic ring-substituted ( E)-3-phenylpropenals and (2 E,4 E)-5-phenylpenta-2,4-dienals.

Published in:

Magnetic Resonance in Chemistry, 1990, v. 28, n. 6, p. 541, doi. 10.1002/mrc.1260280613

By:

Laihia, K.;
Pitkänen, M.;
Nevalainen, Tapio

Publication type:

Article

Comparative molecular field analysis and molecular dynamics studies of α/β hydrolase domain containing 6 (ABHD6) inhibitors.

Published in:

Journal of Molecular Modeling, 2015, v. 21, n. 10, p. 1, doi. 10.1007/s00894-015-2789-8

By:

Kaczor, Agnieszka;
Targowska-Duda, Katarzyna;
Patel, Jayendra;
Laitinen, Tuomo;
Parkkari, Teija;
Adams, Yahaya;
Nevalainen, Tapio;
Poso, Antti

Publication type:

Article

Number of sons contributes to ageing-associated inflammation.

Published in:

Scientific Reports, 2015, p. 8631, doi. 10.1038/srep08631

By:

Marttila, Saara;
Nevalainen, Tapio;
Kananen, Laura;
Jylhävä, Juulia;
Jylhä, Marja;
Hervonen, Antti;
Ilonen, Jorma;
Hurme, Mikko

Publication type:

Article

Increased Paternal Age at Conception Is Associated with Transcriptomic Changes Involved in Mitochondrial Function in Elderly Individuals.

Published in:

PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0167028

By:

Nevalainen, Tapio;
Kananen, Laura;
Marttila, Saara;
Jylhävä, Juulia;
Jylhä, Marja;
Hervonen, Antti;
Hurme, Mikko

Publication type:

Article

Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals.

Published in:

Clinical Epigenetics, 2017, v. 9, p. 1, doi. 10.1186/s13148-016-0301-7

By:

Nevalainen, Tapio;
Kananen, Laura;
Marttila, Saara;
Jylhävä, Juulia;
Mononen, Nina;
Kähönen, Mika;
Raitakari, Olli T.;
Hervonen, Antti;
Jylhä, Marja;
Lehtimäki, Terho;
Hurme, Mikko

Publication type:

Article

Effect of age and sex differences on the abundances of neuronal, glial, and endothelial cells in non-diseased brain tissue.

Published in:

PLoS ONE, 2024, v. 19, n. 12, p. 1, doi. 10.1371/journal.pone.0313855

By:

Autio-Kimura, Arttu;
Nevalainen, Tapio;
Hurme, Mikko

Publication type:

Article

Ageing-associated changes in the human DNA methylome: genomic locations and effects on gene expression.

Published in:

BMC Genomics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12864-015-1381-z

By:

Marttila, Saara;
Kananen, Laura;
Häyrynen, Sergei;
Jylhävä, Juulia;
Nevalainen, Tapio;
Hervonen, Antti;
Jylhä, Marja;
Nykter, Matti;
Hurme, Mikko

Publication type:

Article

Novel Water-Soluble Quaternary Piperazine Derivatives of Chitosan: Synthesis and Characterization.

Published in:

Macromolecular Bioscience, 2006, v. 6, n. 2, p. 139, doi. 10.1002/mabi.200500202

By:

Holappa, Jukka;
Nevalainen, Tapio;
Safin, Rustam;
Soininen, Pasi;
Asplund, Tomas;
Luttikhedde, Tiina;
Másson, Már;
Järvinen, Tomi

Publication type:

Article

Synthesis and in-vitro/in-vivo evaluation of orally administered entacapone prodrugs.

Published in:

Journal of Pharmacy & Pharmacology, 2001, v. 53, n. 11, p. 1489, doi. 10.1211/0022357011778025

By:

Leppänen, Jukka;
Savolainen, Jouko;
Nevalainen, Tapio;
Forsberg, Markus;
Huuskonen, Juhani;
Taipale, Hannu;
Gynther, Jukka;
Männistö, Pekka T.;
Järvinen, Tomi

Publication type:

Article

Inhibitory effects and oxidation of 6-methylcoumarin, 7-methylcoumarin and 7-formylcoumarin via human CYP2A6 and its mouse and pig orthologous enzymes.

Published in:

Xenobiotica, 2016, v. 46, n. 1, p. 14, doi. 10.3109/00498254.2015.1048327

By:

Juvonen, Risto O.;
Kuusisto, Mira;
Fohrgrup, Carolin;
Pitkänen, Mari H.;
Nevalainen, Tapio J.;
Auriola, Seppo;
Raunio, Hannu;
Pasanen, Markku;
Pentikäinen, Olli T.

Publication type:

Article

Characterization of the role of distinct plasma cell-free DNA species in age-associated inflammation and frailty.

Published in:

Aging Cell, 2013, v. 12, n. 3, p. 388, doi. 10.1111/acel.12058

By:

Jylhävä, Juulia;
Nevalainen, Tapio;
Marttila, Saara;
Jylhä, Marja;
Hervonen, Antti;
Hurme, Mikko

Publication type:

Article

Optimization of 1,2,5-Thiadiazole Carbamates as Potent and Selective ABHD6 Inhibitors.

Published in:

ChemMedChem, 2015, v. 10, n. 2, p. 253, doi. 10.1002/cmdc.201402453

By:

Patel, Jayendra Z.;
Nevalainen, Tapio J.;
Savinainen, Juha R.;
Adams, Yahaya;
Laitinen, Tuomo;
Runyon, Robert S.;
Vaara, Miia;
Ahenkorah, Stephen;
Kaczor, Agnieszka A.;
Navia‐Paldanius, Dina;
Gynther, Mikko;
Aaltonen, Niina;
Joharapurkar, Amit A.;
Jain, Mukul R.;
Haka, Abigail S.;
Maxfield, Frederick R.;
Laitinen, Jarmo T.;
Parkkari, Teija

Publication type:

Article

Screening of Various Hormone-Sensitive Lipase Inhibitors as Endocannabinoid-Hydrolyzing Enzyme Inhibitors.

Published in:

ChemMedChem, 2009, v. 4, n. 8, p. 1253, doi. 10.1002/cmdc.200900137

By:

Minkkilä, Anna;
Savinainen, Juha R.;
Käsnänen, Heikki;
Xhaard, Henri;
Nevalainen, Tapio;
Laitinen, Jarmo T.;
Poso, Antti;
Leppänen, Jukka;
Saario, Susanna M.

Publication type:

Article

Composition of the infiltrating immune cells in the brain of healthy individuals: effect of aging.

Published in:

Immunity & Ageing, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12979-022-00302-y

By:

Nevalainen, Tapio;
Autio, Arttu;
Hurme, Mikko

Publication type:

Article

Herpesviruses and their genetic diversity in the blood virome of healthy individuals: effect of aging.

Published in:

Immunity & Ageing, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12979-022-00268-x

By:

Autio, Arttu;
Kettunen, Jalmari;
Nevalainen, Tapio;
Kimura, Bryn;
Hurme, Mikko

Publication type:

Article