Works by Neubauer, Heidi A.

Results: 21

High Efficacy and Drug Synergy of HDAC6-Selective Inhibitor NN-429 in Natural Killer (NK)/T-Cell Lymphoma.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 11, p. 1321, doi. 10.3390/ph15111321

By:

Garcha, Harsimran Kaur;
Nawar, Nabanita;
Sorger, Helena;
Erdogan, Fettah;
Aung, Myint Myat Khine;
Sedighi, Abootaleb;
Manaswiyoungkul, Pimyupa;
Seo, Hyuk-Soo;
Schönefeldt, Susann;
Pölöske, Daniel;
Dhe-Paganon, Sirano;
Neubauer, Heidi A.;
Mustjoki, Satu M.;
Herling, Marco;
de Araujo, Elvin D.;
Moriggl, Richard;
Gunning, Patrick T.

Publication type:

Article

Emerging therapeutic targets in myeloproliferative neoplasms and peripheral T-cell leukemia and lymphomas.

Published in:

Expert Opinion on Therapeutic Targets, 2018, v. 22, n. 1, p. 45, doi. 10.1080/14728222.2018.1406924

By:

Orlova, Anna;
Wingelhofer, Bettina;
Neubauer, Heidi A.;
Maurer, Barbara;
Berger-Becvar, Angelika;
Keserű, György Miklós;
Gunning, Patrick T.;
Valent, Peter;
Moriggl, Richard

Publication type:

Article

STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway.

Published in:

Molecular Cancer, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12943-023-01825-8

By:

Pencik, Jan;
Philippe, Cecile;
Schlederer, Michaela;
Atas, Emine;
Pecoraro, Matteo;
Grund-Gröschke, Sandra;
Li, Wen;
Tracz, Amanda;
Heidegger, Isabel;
Lagger, Sabine;
Trachtová, Karolína;
Oberhuber, Monika;
Heitzer, Ellen;
Aksoy, Osman;
Neubauer, Heidi A.;
Wingelhofer, Bettina;
Orlova, Anna;
Witzeneder, Nadine;
Dillinger, Thomas;
Redl, Elisa

Publication type:

Article

KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis.

Published in:

Molecular Cancer, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12943-022-01542-8

By:

Limberger, Tanja;
Schlederer, Michaela;
Trachtová, Karolina;
Garces de los Fayos Alonso, Ines;
Yang, Jiaye;
Högler, Sandra;
Sternberg, Christina;
Bystry, Vojtech;
Oppelt, Jan;
Tichý, Boris;
Schmeidl, Margit;
Kodajova, Petra;
Jäger, Anton;
Neubauer, Heidi A.;
Oberhuber, Monika;
Schmalzbauer, Belinda S.;
Pospisilova, Sarka;
Dolznig, Helmut;
Wadsak, Wolfgang;
Culig, Zoran

Publication type:

Article

Roles, regulation and inhibitors of sphingosine kinase 2.

Published in:

FEBS Journal, 2013, v. 280, n. 21, p. 5317, doi. 10.1111/febs.12314

By:

Neubauer, Heidi A.;
Pitson, Stuart M.

Publication type:

Article

The neonatal microenvironment programs innate γδ T cells through the transcription factor STAT5.

Published in:

2020

By:

Kadekar, Darshana;
Agerholm, Rasmus;
Rizk, John;
Neubauer, Heidi A.;
Suske, Tobias;
Maurer, Barbara;
Viñals, Monica Torrellas;
Comelli, Elena M.;
Taibi, Amel;
Moriggl, Richard;
Bekiaris, Vasileios

Publication type:

journal article

Dual specific STAT3/5 degraders effectively block acute myeloid leukemia and natural killer/T cell lymphoma.

Published in:

HemaSphere, 2024, v. 8, n. 12, p. 1, doi. 10.1002/hem3.70001

By:

Pölöske, Daniel;
Sorger, Helena;
Schönbichler, Anna;
de Araujo, Elvin D.;
Neubauer, Heidi A.;
Orlova, Anna;
Timonen, Sanna H.;
Abdallah, Diaaeldin I.;
Ianevski, Aleksandr;
Kuusanmäki, Heikki;
Surbek, Marta;
Heyes, Elisabeth;
Eder, Thomas;
Wagner, Christina;
Suske, Tobias;
Metzelder, Martin L.;
Bergmann, Michael;
Dahlhoff, Maik;
Grebien, Florian;
Fleck, Roman

Publication type:

Article

P993: INCREASED STAT5B LEVELS IN MYELOPROLIFERATIVE NEOPLASMS LEAD TO ENHANCED MEGAKARYOCYTIC DIFFERENTIATION CORRELATING WITH THROMBOSIS.

Published in:

HemaSphere, 2023, v. 7, p. 1, doi. 10.1097/01.HS9.0000970876.19398.b4

By:

Ploderer, Marie;
Maurer, Barbara;
Schreiberhuber, Lena;
Suske, Tobias;
Feurstein, Gabriela;
Song, Jihyun;
Prchal, Josef;
Moriggl, Richard;
Neubauer, Heidi

Publication type:

Article

Cell Metabolism Control Through O-GlcNAcylation of STAT5: A Full or Empty Fuel Tank Makes a Big Difference for Cancer Cell Growth and Survival.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 5, p. 1028, doi. 10.3390/ijms20051028

By:

Rauth, Manuel;
Freund, Patricia;
Orlova, Anna;
Grünert, Stefan;
Tasic, Nikola;
Han, Xiaonan;
Ruan, Hai-Bin;
Neubauer, Heidi A.;
Moriggl, Richard

Publication type:

Article

ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41229-2

By:

Ebner, Jessica;
Schmoellerl, Johannes;
Piontek, Martin;
Manhart, Gabriele;
Troester, Selina;
Carter, Bing Z.;
Neubauer, Heidi;
Moriggl, Richard;
Szakács, Gergely;
Zuber, Johannes;
Köcher, Thomas;
Andreeff, Michael;
Sperr, Wolfgang R.;
Valent, Peter;
Grebien, Florian

Publication type:

Article

STAT5 is Expressed in CD34+/CD38− Stem Cells and Serves as a Potential Molecular Target in Ph-Negative Myeloproliferative Neoplasms.

Published in:

Cancers, 2020, v. 12, n. 4, p. 1021, doi. 10.3390/cancers12041021

By:

Hadzijusufovic, Emir;
Keller, Alexandra;
Berger, Daniela;
Greiner, Georg;
Wingelhofer, Bettina;
Witzeneder, Nadine;
Ivanov, Daniel;
Pecnard, Emmanuel;
Nivarthi, Harini;
Schur, Florian K. M.;
Filik, Yüksel;
Kornauth, Christoph;
Neubauer, Heidi A.;
Müllauer, Leonhard;
Tin, Gary;
Park, Jisung;
de Araujo, Elvin D.;
Gunning, Patrick T.;
Hoermann, Gregor;
Gouilleux, Fabrice

Publication type:

Article

Pharmacological Inhibition of Oncogenic STAT3 and STAT5 Signaling in Hematopoietic Cancers.

Published in:

Cancers, 2020, v. 12, n. 1, p. 240, doi. 10.3390/cancers12010240

By:

Brachet-Botineau, Marie;
Polomski, Marion;
Neubauer, Heidi A.;
Juen, Ludovic;
Hédou, Damien;
Viaud-Massuard, Marie-Claude;
Prié, Gildas;
Gouilleux, Fabrice

Publication type:

Article

Structural Implications of STAT3 and STAT5 SH2 Domain Mutations.

Published in:

Cancers, 2019, v. 11, n. 11, p. 1757, doi. 10.3390/cancers11111757

By:

de Araujo, Elvin D.;
Orlova, Anna;
Neubauer, Heidi A.;
Bajusz, Dávid;
Seo, Hyuk-Soo;
Dhe-Paganon, Sirano;
Keserű, György M.;
Moriggl, Richard;
Gunning, Patrick T.

Publication type:

Article

STAT3 and STAT5 Activation in Solid Cancers.

Published in:

Cancers, 2019, v. 11, n. 10, p. 1428, doi. 10.3390/cancers11101428

By:

Igelmann, Sebastian;
Neubauer, Heidi A.;
Ferbeyre, Gerardo

Publication type:

Article

Cell-autonomous IL6ST activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment.

Published in:

Molecular Cancer, 2024, p. 1, doi. 10.1186/s12943-024-02114-8

By:

Sternberg, Christina;
Raigel, Martin;
Limberger, Tanja;
Trachtová, Karolína;
Schlederer, Michaela;
Lindner, Desiree;
Kodajova, Petra;
Yang, Jiaye;
Ziegler, Roman;
Kalla, Jessica;
Stoiber, Stefan;
Dey, Saptaswa;
Zwolanek, Daniela;
Neubauer, Heidi A.;
Oberhuber, Monika;
Redmer, Torben;
Hejret, Václav;
Tichy, Boris;
Tomberger, Martina;
Harbusch, Nora S.

Publication type:

Article

JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression.

Published in:

Molecular Cancer, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12943-024-02022-x

By:

Redmer, Torben;
Raigel, Martin;
Sternberg, Christina;
Ziegler, Roman;
Probst, Clara;
Lindner, Desiree;
Aufinger, Astrid;
Limberger, Tanja;
Trachtova, Karolina;
Kodajova, Petra;
Högler, Sandra;
Schlederer, Michaela;
Stoiber, Stefan;
Oberhuber, Monika;
Bolis, Marco;
Neubauer, Heidi A.;
Miranda, Sara;
Tomberger, Martina;
Harbusch, Nora S.;
Garces de los Fayos Alonso, Ines

Publication type:

Article

The Diverse Roles of γδ T Cells in Cancer: From Rapid Immunity to Aggressive Lymphoma.

Published in:

Cancers, 2021, v. 13, n. 24, p. 6212, doi. 10.3390/cancers13246212

By:

Schönefeldt, Susann;
Wais, Tamara;
Herling, Marco;
Mustjoki, Satu;
Bekiaris, Vasileios;
Moriggl, Richard;
Neubauer, Heidi A.

Publication type:

Article

Proteomic Analysis Identifies NDUFS1 and ATP5O as Novel Markers for Survival Outcome in Prostate Cancer.

Published in:

Cancers, 2021, v. 13, n. 23, p. 6036, doi. 10.3390/cancers13236036

By:

Wiebringhaus, Robert;
Pecoraro, Matteo;
Neubauer, Heidi A.;
Trachtová, Karolína;
Trimmel, Bettina;
Wieselberg, Maritta;
Pencik, Jan;
Egger, Gerda;
Krall, Christoph;
Moriggl, Richard;
Mann, Matthias;
Hantusch, Brigitte;
Kenner, Lukas

Publication type:

Article

A Recurrent STAT5B N642H Driver Mutation in Feline Alimentary T Cell Lymphoma.

Published in:

Cancers, 2021, v. 13, n. 20, p. 5238, doi. 10.3390/cancers13205238

By:

Kieslinger, Matthias;
Swoboda, Alexander;
Kramer, Nina;
Freund, Patricia;
Pratscher, Barbara;
Neubauer, Heidi A.;
Steinborn, Ralf;
Wolfesberger, Birgitt;
Fuchs-Baumgartinger, Andrea;
Moriggl, Richard;
Burgener, Iwan A.

Publication type:

Article

Kelch-like protein 5-mediated ubiquitination of lysine 183 promotes proteasomal degradation of sphingosine kinase 1.

Published in:

Biochemical Journal, 2019, v. 476, n. 21, p. 3211, doi. 10.1042/BCJ20190245

By:

Powell, Jason A.;
Pitman, Melissa R.;
Zebol, Julia R.;
Moretti, Paul A. B.;
Neubauer, Heidi A.;
Davies, Lorena T.;
Lewis, Alexander C.;
Dagley, Laura F.;
Webb, Andrew I.;
Costabile, Maurizio;
Pitson, Stuart M.

Publication type:

Article

Structural and functional consequences of the STAT5B<sup>N642H</sup> driver mutation.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10422-7

By:

de Araujo, Elvin D.;
Erdogan, Fettah;
Neubauer, Heidi A.;
Meneksedag-Erol, Deniz;
Manaswiyoungkul, Pimyupa;
Eram, Mohammad S.;
Seo, Hyuk-Soo;
Qadree, Abdul K.;
Israelian, Johan;
Orlova, Anna;
Suske, Tobias;
Pham, Ha T. T.;
Boersma, Auke;
Tangermann, Simone;
Kenner, Lukas;
Rülicke, Thomas;
Dong, Aiping;
Ravichandran, Manimekalai;
Brown, Peter J.;
Audette, Gerald F.

Publication type:

Article