Works by Neschen, Susanne

Results: 29

Machine Learning Approaches Reveal Metabolic Signatures of Incident Chronic Kidney Disease in Individuals With Prediabetes and Type 2 Diabetes.

Published in:

2020

By:

Huang, Jialing;
Huth, Cornelia;
Covic, Marcela;
Troll, Martina;
Adam, Jonathan;
Zukunft, Sven;
Prehn, Cornelia;
Wang, Li;
Nano, Jana;
Scheerer, Markus F.;
Neschen, Susanne;
Kastenmüller, Gabi;
Suhre, Karsten;
Laxy, Michael;
Schliess, Freimut;
Gieger, Christian;
Adamski, Jerzy;
Hrabe de Angelis, Martin;
Peters, Annette;
Wang-Sattler, Rui

Publication type:

journal article

Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance.

Published in:

2017

By:

Hernández, Elisa Álvarez;
Kahl, Sabine;
Seelig, Anett;
Begovatz, Paul;
Irmler, Martin;
Kupriyanova, Yuliya;
Nowotny, Bettina;
Nowotny, Peter;
Herder, Christian;
Barosa, Cristina;
Carvalho, Filipa;
Rozman, Jan;
Neschen, Susanne;
Jones, John G.;
Beckers, Johannes;
de Angelis, Martin Hrabě;
Roden, Michael

Publication type:

journal article

The central melanocortin system directly controls peripheral lipid metabolism.

Published in:

2007

By:

Nogueiras, Ruben;
Wiedmer, Petra;
Perez-Tilve, Diego;
Veyrat-Durebex, Christelle;
Keogh, Julia M.;
Sutton, Gregory M.;
Pfluger, Paul T.;
Castaneda, Tamara R.;
Neschen, Susanne;
Hofmann, Susanna M.;
Howles, Philip N.;
Morgan, Donald A.;
Benoit, Stephen C.;
Szanto, Ildiko;
Schrott, Brigitte;
Schürmann, Annette;
Joost, Hans-Georg;
Hammond, Craig;
Hui, David Y.;
Woods, Stephen C.

Publication type:

journal article

Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.

Published in:

2005

By:

Morino, Katsutaro;
Petersen, Kitt Falk;
Dufour, Sylvie;
Befroy, Douglas;
Frattini, Jared;
Shatzkes, Nadine;
Neschen, Susanne;
White, Morris F.;
Bilz, Stefan;
Sono, Saki;
Pypaert, Marc;
Shulman, Gerald I.

Publication type:

journal article

Validation of Candidate Phospholipid Biomarkers of Chronic Kidney Disease in Hyperglycemic Individuals and Their Organ-Specific Exploration in Leptin Receptor-Deficient db/db Mouse.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 2, p. 89, doi. 10.3390/metabo11020089

By:

Huang, Jialing;
Covic, Marcela;
Huth, Cornelia;
Rommel, Martina;
Adam, Jonathan;
Zukunft, Sven;
Prehn, Cornelia;
Wang, Li;
Nano, Jana;
Scheerer, Markus F.;
Neschen, Susanne;
Kastenmüller, Gabi;
Gieger, Christian;
Laxy, Michael;
Schliess, Freimut;
Adamski, Jerzy;
Suhre, Karsten;
de Angelis, Martin Hrabe;
Peters, Annette;
Wang-Sattler, Rui

Publication type:

Article

High-Fat, Carbohydrate-Free Diet Markedly Aggravates Obesity but Prevents β-Cell Loss and Diabetes in the Obese, Diabetes-Susceptible db/db Strain.

Published in:

Obesity Facts: The European Journal of Obesity, 2008, v. 1, n. 6, p. 292, doi. 10.1159/000176064

By:

Mirhashemi, Farshad;
Kluth, Oliver;
Scherneck, Stephan;
Vogel, Heike;
Kluge, Reinhart;
Schürmann, Annette;
Joost, Hans-Georg;
Neschen, Susanne

Publication type:

Article

Distinct signatures of host-microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet.

Published in:

ISME Journal: Multidisciplinary Journal of Microbial Ecology, 2014, v. 8, n. 12, p. 2380, doi. 10.1038/ismej.2014.79

By:

Walker, Alesia;
Pfitzner, Barbara;
Neschen, Susanne;
Kahle, Melanie;
Harir, Mourad;
Lucio, Marianna;
Moritz, Franco;
Tziotis, Dimitrios;
Witting, Michael;
Rothballer, Michael;
Engel, Marion;
Schmid, Michael;
Endesfelder, David;
Klingenspor, Martin;
Rattei, Thomas;
Castell, Wolfgang zu;
de Angelis, Martin Hrabé;
Hartmann, Anton;
Schmitt-Kopplin, Philippe

Publication type:

Article

eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription.

Published in:

Nature Communications, 2015, v. 6, n. 9, p. 8261, doi. 10.1038/ncomms9261

By:

Brina, Daniela;
Miluzio, Annarita;
Ricciardi, Sara;
Clarke, Kim;
Davidsen, Peter K.;
Viero, Gabriella;
Tebaldi, Toma;
Offenhäuser, Nina;
Rozman, Jan;
Rathkolb, Birgit;
Neschen, Susanne;
Klingenspor, Martin;
Wolf, Eckhard;
Gailus-Durner, Valerie;
Fuchs, Helmut;
Hrabe de Angelis, Martin;
Quattrone, Alessandro;
Falciani, Francesco;
Biffo, Stefano

Publication type:

Article

Bidirectional modulation of TCA cycle metabolites and anaplerosis by metformin and its combination with SGLT2i.

Published in:

Cardiovascular Diabetology, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12933-024-02288-x

By:

Harada, Makoto;
Adam, Jonathan;
Covic, Marcela;
Ge, Jianhong;
Brandmaier, Stefan;
Muschet, Caroline;
Huang, Jialing;
Han, Siyu;
Rommel, Martina;
Rotter, Markus;
Heier, Margit;
Mohney, Robert P.;
Krumsiek, Jan;
Kastenmüller, Gabi;
Rathmann, Wolfgang;
Zou, Zhongmei;
Zukunft, Sven;
Scheerer, Markus F.;
Neschen, Susanne;
Adamski, Jerzy

Publication type:

Article

Dual role of proapoptotic BAD in insulin secretion and beta cell survival.

Published in:

Nature Medicine, 2008, v. 14, n. 2, p. 144, doi. 10.1038/nm1717

By:

Danial, Nika N.;
Walensky, Loren D.;
Zhang, Chen-Yu;
Choi, Cheol Soo;
Fisher, Jill K.;
Molina, Anthony J. A.;
Datta, Sandeep Robert;
Pitter, Kenneth L.;
Bird, Gregory H.;
Wikstrom, Jakob D.;
Deeney, Jude T.;
Robertson, Kirsten;
Morash, Joel;
Kulkarni, Ameya;
Neschen, Susanne;
Kim, Sheene;
Greenberg, Michael E.;
Corkey, Barbara E.;
Shirihai, Orian S.;
Shulman, Gerald I.

Publication type:

Article

Response to Comment on Adam et al. Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues. Diabetes 2016;65:3776-3785.

Published in:

2017

By:

Adam, Jonathan;
Brandmaier, Stefan;
Troll, Martina;
Rotter, Markus;
Mohney, Robert P.;
Heier, Margit;
Adamski, Jerzy;
Yixue Li;
Neschen, Susanne;
Kastenmüller, Gabi;
Suhre, Karsten;
Ankerst, Donna;
Meitinger, Thomas;
Rui Wang-Sattler;
Li, Yixue;
Wang-Sattler, Rui

Publication type:

Letter

Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice.

Published in:

2016

By:

Franko, Andras;
Huypens, Peter;
Neschen, Susanne;
Irmler, Martin;
Rozman, Jan;
Rathkolb, Birgit;
Neff, Frauke;
Prehn, Cornelia;
Dubois, Guillaume;
Baumann, Martina;
Massinger, Rebecca;
Gradinger, Daniel;
Przemeck, Gerhard K. H.;
Repp, Birgit;
Aichler, Michaela;
Feuchtinger, Annette;
Schommers, Philipp;
Stöhr, Oliver;
Sanchez-Lasheras, Carmen;
Adamski, Jerzy

Publication type:

journal article

Metformin Supports the Antidiabetic Effect of a Sodium Glucose Cotransporter 2 Inhibitor by Suppressing Endogenous Glucose Production in Diabetic Mice.

Published in:

Diabetes, 2015, v. 64, n. 1, p. 284, doi. 10.2337/db14-0393

By:

Neschen, Susanne;
Scheerer, Markus;
Seelig, Anett;
Huypens, Peter;
Schultheiss, Jürgen;
Wu, Moya;
Wurst, Wolfgang;
Rathkolb, Birgit;
Suhre, Karsten;
Wolf, Eckhard;
Beckers, Johannes;
de Angelis, Martin Hrabé

Publication type:

Article

Muscle-specific IRS-1 Ser->Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle.

Published in:

2008

By:

Morino K;
Neschen S;
Bilz S;
Sono S;
Tsirigotis D;
Reznick RM;
Moore I;
Nagai Y;
Samuel V;
Sebastian D;
White M;
Philbrick W;
Shulman GI;
Morino, Katsutaro;
Neschen, Susanne;
Bilz, Stefan;
Sono, Saki;
Tsirigotis, Dimitrios;
Reznick, Richard M;
Moore, Irene

Publication type:

journal article

Muscle-Specific IRS-1 Ser→ Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle.

Published in:

Diabetes, 2008, v. 57, n. 10, p. 2644, doi. 10.2337/db06-0454

By:

Morino, Katsutaro;
Neschen, Susanne;
Bilz, Stefan;
Sono, Saki;
Tsirigotis, Dimitrios;
Reznick, Richard M.;
Moore, Irene;
Nagai, Yoshio;
Samuel, Varman;
Sebastian, David;
White, Morris;
Philbrick, William;
Shulman, Gerald I.

Publication type:

Article

Carbohydrate Restriction Protects Diabetes-Prone db/db and NZO Mice from Beta-Ceil Failure.

Published in:

Diabetes, 2007, v. 56, p. A302

By:

Neschen, Susanne;
Mirhashemi, Farshad;
Scherneck, Stephan;
Nestler, Matthias;
Kluge, Reinhart;
Schurmann, Annette;
Joost, Hans-Georg

Publication type:

Article

n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-alpha-dependent manner.

Published in:

2007

By:

Neschen S;
Morino K;
Dong J;
Wang-Fischer Y;
Cline GW;
Romanelli AJ;
Rossbacher JC;
Moore IK;
Regittnig W;
Munoz DS;
Kim JH;
Shulman GI;
Neschen, Susanne;
Morino, Katsutaro;
Dong, Jianying;
Wang-Fischer, Yanlin;
Cline, Gary W;
Romanelli, Anthony J;
Rossbacher, Jörg C;
Moore, Irene K

Publication type:

journal article

n-3 Fatty Acids Preserve Insulin Sensitivity In Vivo in a Peroxisome Proliferator-Activated Receptor-α-Dependent Manner.

Published in:

Diabetes, 2007, v. 56, n. 4, p. 1034, doi. 10.2337/db06-1206

By:

Neschen, Susanne;
Morino, Katsutaro;
Dong, Jianying;
Wang-Fischer, Yanlin;
Cline, Gary W.;
Romanelli, Anthony J.;
Rossbacher, Jörg C.;
Moore, Irene K.;
Regittnig, Werner;
Munoz, David S.;
Kim, Jung H.;
Shulman, Gerald I.

Publication type:

Article

Immunoneutralization of Endogenous Glucagon Reduces Hepatic Glucose Output and Improves Long-Term Glycemic Control in Diabetic ob/ob Mice.

Published in:

Diabetes, 2006, v. 55, n. 10, p. 2843, doi. 10.2337/db06-0222

By:

Sørensen, Heidi;
Brand, Christian L.;
Neschen, Susanne;
Holst, Jens Juul;
Fosgerau, Keld;
Nishimura, Erica;
Shulman, Gerald I.

Publication type:

Article

Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-gamma-dependent mechanism in mice.

Published in:

2006

By:

Neschen S;
Morino K;
Rossbacher JC;
Pongratz RL;
Cline GW;
Sono S;
Gillum M;
Shulman GI;
Neschen, Susanne;
Morino, Katsutaro;
Rossbacher, Jörg C;
Pongratz, Rebecca L;
Cline, Gary W;
Sono, Saki;
Gillum, Matthew;
Shulman, Gerald I

Publication type:

journal article

Fish Oil Regulates Adiponectin Secretion by a Peroxisome Proliferator-Activated Receptor-γ--Dependent Mechanism in Mice.

Published in:

Diabetes, 2006, v. 55, n. 4, p. 924, doi. 10.2337/diabetes.55.04.06.db05-0985

By:

Neschen, Susanne;
Morino, Katsutaro;
Rossbacher, Jörg C.;
Pongratz, Rebecca L.;
Cline, Gary W.;
Sono, Saki;
Gillum, Matthew;
Shulman, Gerald I.

Publication type:

Article

Direct thiazolidinedione action on isolated rat skeletal muscle fuel handling is independent of peroxisome proliferator-activated receptor-gamma-mediated changes in gene expression.

Published in:

2001

By:

Brunmair, Barbara;
Gras, Florian;
Neschen, Susanne;
Roden, Michael;
Wagner,, Ludwig;
Waldhausl, Werner;
Furnsinn, Clemens;
Brunmair, B;
Gras, F;
Neschen, S;
Roden, M;
Wagner, L;
Waldhäusl, W;
Fürnsinn, C

Publication type:

journal article

Retinal proteome alterations in a mouse model of type 2 diabetes.

Published in:

Diabetologia, 2014, v. 57, n. 1, p. 192, doi. 10.1007/s00125-013-3070-2

By:

Ly, Alice;
Scheerer, Markus F.;
Zukunft, Sven;
Muschet, Caroline;
Merl, Juliane;
Adamski, Jerzy;
Hrabě de Angelis, Martin;
Neschen, Susanne;
Hauck, Stefanie M.;
Ueffing, Marius

Publication type:

Article

The impact of blood on liver metabolite profiling - a combined metabolomic and proteomic approach.

Published in:

Biomedical Chromatography, 2014, v. 28, n. 2, p. 231, doi. 10.1002/bmc.3010

By:

Ly‐Verdú, Saray;
Schaefer, Alexander;
Kahle, Melanie;
Groeger, Thomas;
Neschen, Susanne;
Arteaga‐Salas, Jose M.;
Ueffing, Marius;
Angelis, Martin Hrabe;
Zimmermann, Ralf

Publication type:

Article

Machine Learning Approaches Reveal Metabolic Signatures of Incident Chronic Kidney Disease in Individuals With Prediabetes and Type 2 Diabetes.

Published in:

Diabetes, 2020, v. 69, n. 12, p. 2756, doi. 10.2337/db20-0586

By:

Huang, Jialing;
Huth, Cornelia;
Covic, Marcela;
Troll, Martina;
Adam, Jonathan;
Zukunft, Sven;
Prehn, Cornelia;
Wang, Li;
Nano, Jana;
Scheerer, Markus F.;
Neschen, Susanne;
Kastenmüller, Gabi;
Suhre, Karsten;
Laxy, Michael;
Schliess, Freimut;
Gieger, Christian;
Adamski, Jerzy;
Hrabe de Angelis, Martin;
Peters, Annette;
Wang-Sattler, Rui

Publication type:

Article

Combining metabolomic non-targeted GC×GC-ToF-MS analysis and chemometric ASCA-based study of variances to assess dietary influence on type 2 diabetes development in a mouse model.

Published in:

Analytical & Bioanalytical Chemistry, 2015, v. 407, n. 1, p. 343, doi. 10.1007/s00216-014-8227-4

By:

Ly-Verdú, Saray;
Gröger, Thomas;
Arteaga-Salas, Jose;
Brandmaier, Stefan;
Kahle, Melanie;
Neschen, Susanne;
Harbě de Angelis, Martin;
Zimmermann, Ralf

Publication type:

Article

Innovations in phenotyping of mouse models in the German Mouse Clinic.

Published in:

Mammalian Genome, 2012, v. 23, n. 9/10, p. 611, doi. 10.1007/s00335-012-9415-1

By:

Fuchs, Helmut;
Gailus-Durner, Valérie;
Neschen, Susanne;
Adler, Thure;
Afonso, Luciana;
Aguilar-Pimentel, Juan;
Becker, Lore;
Bohla, Alexander;
Calzada-Wack, Julia;
Cohrs, Christian;
Dewert, Anna;
Fridrich, Barbara;
Garrett, Lillian;
Glasl, Lisa;
Götz, Alexander;
Hans, Wolfgang;
Hölter, Sabine;
Horsch, Marion;
Hurt, Anja;
Janas, Eva

Publication type:

Article

Antibody-independent B cell-intrinsic and -extrinsic roles for CD21/35.

Published in:

European Journal of Immunology, 2006, v. 36, n. 9, p. 2384, doi. 10.1002/eji.200636172

By:

Rossbacher, Joerg;
Haberman, Ann M.;
Neschen, Susanne;
Khalil, Ashraf;
Shlomchik, Mark J.

Publication type:

Article

Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-14004-5

By:

Santos, Maria C. Ferreira dos;
Anderson, Cole P.;
Neschen, Susanne;
Zumbrennen-Bullough, Kimberly B.;
Romney, Steven J.;
Kahle-Stephan, Melanie;
Rathkolb, Birgit;
Gailus-Durner, Valerie;
Fuchs, Helmut;
Wolf, Eckhard;
Rozman, Jan;
de Angelis, Martin Hrabe;
Cai, Weiling Maggie;
Rajan, Malini;
Hu, Jennifer;
Dedon, Peter C.;
Leibold, Elizabeth A.

Publication type:

Article