Works by Neschen, Susanne

Results: 29

Machine Learning Approaches Reveal Metabolic Signatures of Incident Chronic Kidney Disease in Individuals With Prediabetes and Type 2 Diabetes.
Published in:
2020
By:
- Huang, Jialing;
- Huth, Cornelia;
- Covic, Marcela;
- Troll, Martina;
- Adam, Jonathan;
- Zukunft, Sven;
- Prehn, Cornelia;
- Wang, Li;
- Nano, Jana;
- Scheerer, Markus F.;
- Neschen, Susanne;
- Kastenmüller, Gabi;
- Suhre, Karsten;
- Laxy, Michael;
- Schliess, Freimut;
- Gieger, Christian;
- Adamski, Jerzy;
- Hrabe de Angelis, Martin;
- Peters, Annette;
- Wang-Sattler, Rui
Publication type:
journal article
Muscle-specific IRS-1 Ser->Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle.
Published in:
2008
By:
- Morino K;
- Neschen S;
- Bilz S;
- Sono S;
- Tsirigotis D;
- Reznick RM;
- Moore I;
- Nagai Y;
- Samuel V;
- Sebastian D;
- White M;
- Philbrick W;
- Shulman GI;
- Morino, Katsutaro;
- Neschen, Susanne;
- Bilz, Stefan;
- Sono, Saki;
- Tsirigotis, Dimitrios;
- Reznick, Richard M;
- Moore, Irene
Publication type:
journal article
Muscle-Specific IRS-1 Ser→ Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle.
Published in:
Diabetes, 2008, v. 57, n. 10, p. 2644, doi. 10.2337/db06-0454
By:
- Morino, Katsutaro;
- Neschen, Susanne;
- Bilz, Stefan;
- Sono, Saki;
- Tsirigotis, Dimitrios;
- Reznick, Richard M.;
- Moore, Irene;
- Nagai, Yoshio;
- Samuel, Varman;
- Sebastian, David;
- White, Morris;
- Philbrick, William;
- Shulman, Gerald I.
Publication type:
Article
Carbohydrate Restriction Protects Diabetes-Prone db/db and NZO Mice from Beta-Ceil Failure.
Published in:
Diabetes, 2007, v. 56, p. A302
By:
- Neschen, Susanne;
- Mirhashemi, Farshad;
- Scherneck, Stephan;
- Nestler, Matthias;
- Kluge, Reinhart;
- Schurmann, Annette;
- Joost, Hans-Georg
Publication type:
Article
n-3 Fatty acids preserve insulin sensitivity in vivo in a peroxisome proliferator-activated receptor-alpha-dependent manner.
Published in:
2007
By:
- Neschen S;
- Morino K;
- Dong J;
- Wang-Fischer Y;
- Cline GW;
- Romanelli AJ;
- Rossbacher JC;
- Moore IK;
- Regittnig W;
- Munoz DS;
- Kim JH;
- Shulman GI;
- Neschen, Susanne;
- Morino, Katsutaro;
- Dong, Jianying;
- Wang-Fischer, Yanlin;
- Cline, Gary W;
- Romanelli, Anthony J;
- Rossbacher, Jörg C;
- Moore, Irene K
Publication type:
journal article
n-3 Fatty Acids Preserve Insulin Sensitivity In Vivo in a Peroxisome Proliferator-Activated Receptor-α-Dependent Manner.
Published in:
Diabetes, 2007, v. 56, n. 4, p. 1034, doi. 10.2337/db06-1206
By:
- Neschen, Susanne;
- Morino, Katsutaro;
- Dong, Jianying;
- Wang-Fischer, Yanlin;
- Cline, Gary W.;
- Romanelli, Anthony J.;
- Rossbacher, Jörg C.;
- Moore, Irene K.;
- Regittnig, Werner;
- Munoz, David S.;
- Kim, Jung H.;
- Shulman, Gerald I.
Publication type:
Article
Immunoneutralization of Endogenous Glucagon Reduces Hepatic Glucose Output and Improves Long-Term Glycemic Control in Diabetic ob/ob Mice.
Published in:
Diabetes, 2006, v. 55, n. 10, p. 2843, doi. 10.2337/db06-0222
By:
- Sørensen, Heidi;
- Brand, Christian L.;
- Neschen, Susanne;
- Holst, Jens Juul;
- Fosgerau, Keld;
- Nishimura, Erica;
- Shulman, Gerald I.
Publication type:
Article
Fish oil regulates adiponectin secretion by a peroxisome proliferator-activated receptor-gamma-dependent mechanism in mice.
Published in:
2006
By:
- Neschen S;
- Morino K;
- Rossbacher JC;
- Pongratz RL;
- Cline GW;
- Sono S;
- Gillum M;
- Shulman GI;
- Neschen, Susanne;
- Morino, Katsutaro;
- Rossbacher, Jörg C;
- Pongratz, Rebecca L;
- Cline, Gary W;
- Sono, Saki;
- Gillum, Matthew;
- Shulman, Gerald I
Publication type:
journal article
Fish Oil Regulates Adiponectin Secretion by a Peroxisome Proliferator-Activated Receptor-γ--Dependent Mechanism in Mice.
Published in:
Diabetes, 2006, v. 55, n. 4, p. 924, doi. 10.2337/diabetes.55.04.06.db05-0985
By:
- Neschen, Susanne;
- Morino, Katsutaro;
- Rossbacher, Jörg C.;
- Pongratz, Rebecca L.;
- Cline, Gary W.;
- Sono, Saki;
- Gillum, Matthew;
- Shulman, Gerald I.
Publication type:
Article
Direct thiazolidinedione action on isolated rat skeletal muscle fuel handling is independent of peroxisome proliferator-activated receptor-gamma-mediated changes in gene expression.
Published in:
2001
By:
- Brunmair, Barbara;
- Gras, Florian;
- Neschen, Susanne;
- Roden, Michael;
- Wagner,, Ludwig;
- Waldhausl, Werner;
- Furnsinn, Clemens;
- Brunmair, B;
- Gras, F;
- Neschen, S;
- Roden, M;
- Wagner, L;
- Waldhäusl, W;
- Fürnsinn, C
Publication type:
journal article
eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription.
Published in:
Nature Communications, 2015, v. 6, n. 9, p. 8261, doi. 10.1038/ncomms9261
By:
- Brina, Daniela;
- Miluzio, Annarita;
- Ricciardi, Sara;
- Clarke, Kim;
- Davidsen, Peter K.;
- Viero, Gabriella;
- Tebaldi, Toma;
- Offenhäuser, Nina;
- Rozman, Jan;
- Rathkolb, Birgit;
- Neschen, Susanne;
- Klingenspor, Martin;
- Wolf, Eckhard;
- Gailus-Durner, Valerie;
- Fuchs, Helmut;
- Hrabe de Angelis, Martin;
- Quattrone, Alessandro;
- Falciani, Francesco;
- Biffo, Stefano
Publication type:
Article
High-Fat, Carbohydrate-Free Diet Markedly Aggravates Obesity but Prevents β-Cell Loss and Diabetes in the Obese, Diabetes-Susceptible db/db Strain.
Published in:
Obesity Facts: The European Journal of Obesity, 2008, v. 1, n. 6, p. 292, doi. 10.1159/000176064
By:
- Mirhashemi, Farshad;
- Kluth, Oliver;
- Scherneck, Stephan;
- Vogel, Heike;
- Kluge, Reinhart;
- Schürmann, Annette;
- Joost, Hans-Georg;
- Neschen, Susanne
Publication type:
Article
Acute dietary fat intake initiates alterations in energy metabolism and insulin resistance.
Published in:
2017
By:
- Hernández, Elisa Álvarez;
- Kahl, Sabine;
- Seelig, Anett;
- Begovatz, Paul;
- Irmler, Martin;
- Kupriyanova, Yuliya;
- Nowotny, Bettina;
- Nowotny, Peter;
- Herder, Christian;
- Barosa, Cristina;
- Carvalho, Filipa;
- Rozman, Jan;
- Neschen, Susanne;
- Jones, John G.;
- Beckers, Johannes;
- de Angelis, Martin Hrabě;
- Roden, Michael
Publication type:
journal article
Dual role of proapoptotic BAD in insulin secretion and beta cell survival.
Published in:
Nature Medicine, 2008, v. 14, n. 2, p. 144, doi. 10.1038/nm1717
By:
- Danial, Nika N.;
- Walensky, Loren D.;
- Zhang, Chen-Yu;
- Choi, Cheol Soo;
- Fisher, Jill K.;
- Molina, Anthony J. A.;
- Datta, Sandeep Robert;
- Pitter, Kenneth L.;
- Bird, Gregory H.;
- Wikstrom, Jakob D.;
- Deeney, Jude T.;
- Robertson, Kirsten;
- Morash, Joel;
- Kulkarni, Ameya;
- Neschen, Susanne;
- Kim, Sheene;
- Greenberg, Michael E.;
- Corkey, Barbara E.;
- Shirihai, Orian S.;
- Shulman, Gerald I.
Publication type:
Article
Combining metabolomic non-targeted GC×GC-ToF-MS analysis and chemometric ASCA-based study of variances to assess dietary influence on type 2 diabetes development in a mouse model.
Published in:
Analytical & Bioanalytical Chemistry, 2015, v. 407, n. 1, p. 343, doi. 10.1007/s00216-014-8227-4
By:
- Ly-Verdú, Saray;
- Gröger, Thomas;
- Arteaga-Salas, Jose;
- Brandmaier, Stefan;
- Kahle, Melanie;
- Neschen, Susanne;
- Harbě de Angelis, Martin;
- Zimmermann, Ralf
Publication type:
Article
Antibody-independent B cell-intrinsic and -extrinsic roles for CD21/35.
Published in:
European Journal of Immunology, 2006, v. 36, n. 9, p. 2384, doi. 10.1002/eji.200636172
By:
- Rossbacher, Joerg;
- Haberman, Ann M.;
- Neschen, Susanne;
- Khalil, Ashraf;
- Shlomchik, Mark J.
Publication type:
Article
Irp2 regulates insulin production through iron-mediated Cdkal1-catalyzed tRNA modification.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-14004-5
By:
- Santos, Maria C. Ferreira dos;
- Anderson, Cole P.;
- Neschen, Susanne;
- Zumbrennen-Bullough, Kimberly B.;
- Romney, Steven J.;
- Kahle-Stephan, Melanie;
- Rathkolb, Birgit;
- Gailus-Durner, Valerie;
- Fuchs, Helmut;
- Wolf, Eckhard;
- Rozman, Jan;
- de Angelis, Martin Hrabe;
- Cai, Weiling Maggie;
- Rajan, Malini;
- Hu, Jennifer;
- Dedon, Peter C.;
- Leibold, Elizabeth A.
Publication type:
Article
Distinct signatures of host-microbial meta-metabolome and gut microbiome in two C57BL/6 strains under high-fat diet.
Published in:
ISME Journal: Multidisciplinary Journal of Microbial Ecology, 2014, v. 8, n. 12, p. 2380, doi. 10.1038/ismej.2014.79
By:
- Walker, Alesia;
- Pfitzner, Barbara;
- Neschen, Susanne;
- Kahle, Melanie;
- Harir, Mourad;
- Lucio, Marianna;
- Moritz, Franco;
- Tziotis, Dimitrios;
- Witting, Michael;
- Rothballer, Michael;
- Engel, Marion;
- Schmid, Michael;
- Endesfelder, David;
- Klingenspor, Martin;
- Rattei, Thomas;
- Castell, Wolfgang zu;
- de Angelis, Martin Hrabé;
- Hartmann, Anton;
- Schmitt-Kopplin, Philippe
Publication type:
Article
The central melanocortin system directly controls peripheral lipid metabolism.
Published in:
2007
By:
- Nogueiras, Ruben;
- Wiedmer, Petra;
- Perez-Tilve, Diego;
- Veyrat-Durebex, Christelle;
- Keogh, Julia M.;
- Sutton, Gregory M.;
- Pfluger, Paul T.;
- Castaneda, Tamara R.;
- Neschen, Susanne;
- Hofmann, Susanna M.;
- Howles, Philip N.;
- Morgan, Donald A.;
- Benoit, Stephen C.;
- Szanto, Ildiko;
- Schrott, Brigitte;
- Schürmann, Annette;
- Joost, Hans-Georg;
- Hammond, Craig;
- Hui, David Y.;
- Woods, Stephen C.
Publication type:
journal article
Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents.
Published in:
2005
By:
- Morino, Katsutaro;
- Petersen, Kitt Falk;
- Dufour, Sylvie;
- Befroy, Douglas;
- Frattini, Jared;
- Shatzkes, Nadine;
- Neschen, Susanne;
- White, Morris F.;
- Bilz, Stefan;
- Sono, Saki;
- Pypaert, Marc;
- Shulman, Gerald I.
Publication type:
journal article
The impact of blood on liver metabolite profiling - a combined metabolomic and proteomic approach.
Published in:
Biomedical Chromatography, 2014, v. 28, n. 2, p. 231, doi. 10.1002/bmc.3010
By:
- Ly‐Verdú, Saray;
- Schaefer, Alexander;
- Kahle, Melanie;
- Groeger, Thomas;
- Neschen, Susanne;
- Arteaga‐Salas, Jose M.;
- Ueffing, Marius;
- Angelis, Martin Hrabe;
- Zimmermann, Ralf
Publication type:
Article
Innovations in phenotyping of mouse models in the German Mouse Clinic.
Published in:
Mammalian Genome, 2012, v. 23, n. 9/10, p. 611, doi. 10.1007/s00335-012-9415-1
By:
- Fuchs, Helmut;
- Gailus-Durner, Valérie;
- Neschen, Susanne;
- Adler, Thure;
- Afonso, Luciana;
- Aguilar-Pimentel, Juan;
- Becker, Lore;
- Bohla, Alexander;
- Calzada-Wack, Julia;
- Cohrs, Christian;
- Dewert, Anna;
- Fridrich, Barbara;
- Garrett, Lillian;
- Glasl, Lisa;
- Götz, Alexander;
- Hans, Wolfgang;
- Hölter, Sabine;
- Horsch, Marion;
- Hurt, Anja;
- Janas, Eva
Publication type:
Article
Retinal proteome alterations in a mouse model of type 2 diabetes.
Published in:
Diabetologia, 2014, v. 57, n. 1, p. 192, doi. 10.1007/s00125-013-3070-2
By:
- Ly, Alice;
- Scheerer, Markus F.;
- Zukunft, Sven;
- Muschet, Caroline;
- Merl, Juliane;
- Adamski, Jerzy;
- Hrabě de Angelis, Martin;
- Neschen, Susanne;
- Hauck, Stefanie M.;
- Ueffing, Marius
Publication type:
Article
Validation of Candidate Phospholipid Biomarkers of Chronic Kidney Disease in Hyperglycemic Individuals and Their Organ-Specific Exploration in Leptin Receptor-Deficient db/db Mouse.
Published in:
Metabolites (2218-1989), 2021, v. 11, n. 2, p. 89, doi. 10.3390/metabo11020089
By:
- Huang, Jialing;
- Covic, Marcela;
- Huth, Cornelia;
- Rommel, Martina;
- Adam, Jonathan;
- Zukunft, Sven;
- Prehn, Cornelia;
- Wang, Li;
- Nano, Jana;
- Scheerer, Markus F.;
- Neschen, Susanne;
- Kastenmüller, Gabi;
- Gieger, Christian;
- Laxy, Michael;
- Schliess, Freimut;
- Adamski, Jerzy;
- Suhre, Karsten;
- de Angelis, Martin Hrabe;
- Peters, Annette;
- Wang-Sattler, Rui
Publication type:
Article
Machine Learning Approaches Reveal Metabolic Signatures of Incident Chronic Kidney Disease in Individuals With Prediabetes and Type 2 Diabetes.
Published in:
Diabetes, 2020, v. 69, n. 12, p. 2756, doi. 10.2337/db20-0586
By:
- Huang, Jialing;
- Huth, Cornelia;
- Covic, Marcela;
- Troll, Martina;
- Adam, Jonathan;
- Zukunft, Sven;
- Prehn, Cornelia;
- Wang, Li;
- Nano, Jana;
- Scheerer, Markus F.;
- Neschen, Susanne;
- Kastenmüller, Gabi;
- Suhre, Karsten;
- Laxy, Michael;
- Schliess, Freimut;
- Gieger, Christian;
- Adamski, Jerzy;
- Hrabe de Angelis, Martin;
- Peters, Annette;
- Wang-Sattler, Rui
Publication type:
Article
Response to Comment on Adam et al. Metformin Effect on Nontargeted Metabolite Profiles in Patients With Type 2 Diabetes and in Multiple Murine Tissues. Diabetes 2016;65:3776-3785.
Published in:
2017
By:
- Adam, Jonathan;
- Brandmaier, Stefan;
- Troll, Martina;
- Rotter, Markus;
- Mohney, Robert P.;
- Heier, Margit;
- Adamski, Jerzy;
- Yixue Li;
- Neschen, Susanne;
- Kastenmüller, Gabi;
- Suhre, Karsten;
- Ankerst, Donna;
- Meitinger, Thomas;
- Rui Wang-Sattler;
- Li, Yixue;
- Wang-Sattler, Rui
Publication type:
Letter
Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice.
Published in:
2016
By:
- Franko, Andras;
- Huypens, Peter;
- Neschen, Susanne;
- Irmler, Martin;
- Rozman, Jan;
- Rathkolb, Birgit;
- Neff, Frauke;
- Prehn, Cornelia;
- Dubois, Guillaume;
- Baumann, Martina;
- Massinger, Rebecca;
- Gradinger, Daniel;
- Przemeck, Gerhard K. H.;
- Repp, Birgit;
- Aichler, Michaela;
- Feuchtinger, Annette;
- Schommers, Philipp;
- Stöhr, Oliver;
- Sanchez-Lasheras, Carmen;
- Adamski, Jerzy
Publication type:
journal article
Metformin Supports the Antidiabetic Effect of a Sodium Glucose Cotransporter 2 Inhibitor by Suppressing Endogenous Glucose Production in Diabetic Mice.
Published in:
Diabetes, 2015, v. 64, n. 1, p. 284, doi. 10.2337/db14-0393
By:
- Neschen, Susanne;
- Scheerer, Markus;
- Seelig, Anett;
- Huypens, Peter;
- Schultheiss, Jürgen;
- Wu, Moya;
- Wurst, Wolfgang;
- Rathkolb, Birgit;
- Suhre, Karsten;
- Wolf, Eckhard;
- Beckers, Johannes;
- de Angelis, Martin Hrabé
Publication type:
Article
Bidirectional modulation of TCA cycle metabolites and anaplerosis by metformin and its combination with SGLT2i.
Published in:
Cardiovascular Diabetology, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12933-024-02288-x
By:
- Harada, Makoto;
- Adam, Jonathan;
- Covic, Marcela;
- Ge, Jianhong;
- Brandmaier, Stefan;
- Muschet, Caroline;
- Huang, Jialing;
- Han, Siyu;
- Rommel, Martina;
- Rotter, Markus;
- Heier, Margit;
- Mohney, Robert P.;
- Krumsiek, Jan;
- Kastenmüller, Gabi;
- Rathmann, Wolfgang;
- Zou, Zhongmei;
- Zukunft, Sven;
- Scheerer, Markus F.;
- Neschen, Susanne;
- Adamski, Jerzy
Publication type:
Article