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A novel phosphocholine‐mimetic inhibits a pro‐inflammatory conformational change in C‐reactive protein.
Published in:
EMBO Molecular Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.15252/emmm.202216236
By:
- Zeller, Johannes;
- Cheung Tung Shing, Karen S;
- Nero, Tracy L;
- McFadyen, James D;
- Krippner, Guy;
- Bogner, Balázs;
- Kreuzaler, Sheena;
- Kiefer, Jurij;
- Horner, Verena K;
- Braig, David;
- Danish, Habiba;
- Baratchi, Sara;
- Fricke, Mark;
- Wang, Xiaowei;
- Kather, Michel G;
- Kammerer, Bernd;
- Woollard, Kevin J;
- Sharma, Prerna;
- Morton, Craig J;
- Pietersz, Geoffrey
Publication type:
Article
Repurposing the selective estrogen receptor modulator bazedoxifene to suppress gastrointestinal cancer growth.
Published in:
EMBO Molecular Medicine, 2019, v. 11, n. 4, p. N.PAG, doi. 10.15252/emmm.201809539
By:
- Thilakasiri, Pathum;
- Huynh, Jennifer;
- Poh, Ashleigh R;
- Tan, Chin Wee;
- Nero, Tracy L;
- Tran, Kelly;
- Parslow, Adam C;
- Afshar‐Sterle, Shoukat;
- Baloyan, David;
- Hannan, Natalie J;
- Buchert, Michael;
- Scott, Andrew Mark;
- Griffin, Michael DW;
- Hollande, Frederic;
- Parker, Michael W;
- Putoczki, Tracy L;
- Ernst, Matthias;
- Chand, Ashwini L
Publication type:
Article
Crystallization and preliminary X-ray diffraction analysis of the interleukin-3 alpha receptor bound to the Fab fragment of antibody CSL362.
Published in:
Acta Crystallographica: Section F, Structural Biology Communications, 2014, v. 70, n. 3, p. 358, doi. 10.1107/S2053230X14002593
By:
- Broughton, Sophie E.;
- Hercus, Timothy R.;
- Nero, Tracy L.;
- Dhagat, Urmi;
- Owczarek, Catherine M.;
- Hardy, Matthew P.;
- Fabri, Louis J.;
- Scotney, Pierre D.;
- Nash, Andrew D.;
- Wilson, Nicholas J.;
- Lopez, Angel F.;
- Parker, Michael W.
Publication type:
Article
C-reactive protein, immunothrombosis and venous thromboembolism.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1002652
By:
- Dix, Caroline;
- Zeller, Johannes;
- Stevens, Hannah;
- Eisenhardt, Steffen U.;
- Shing, Karen S. Cheung Tung;
- Nero, Tracy L.;
- Morton, Craig J.;
- Parker, Michael W.;
- Peter, Karlheinz;
- McFadyen, James D.
Publication type:
Article
Activity-Modulating Monoclonal Antibodies to the Human Serine Protease HtrA3 Provide Novel Insights into Regulating HtrA Proteolytic Activities.
Published in:
PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0108235
By:
- Singh, Harmeet;
- Nero, Tracy L.;
- Wang, Yao;
- Parker, Michael W.;
- Nie, Guiying
Publication type:
Article
Small Molecule Proprotein Convertase Inhibitors for Inhibition of Embryo Implantation.
Published in:
PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0081380
By:
- Ho, Huiting;
- Singh, Harmeet;
- Heng, Sophea;
- Nero, Tracy L.;
- Paule, Sarah;
- Parker, Michael W.;
- Johnson, Alan T.;
- Jiao, Guan-Sheng;
- Nie, Guiying
Publication type:
Article
The GM- CSF/ IL-3/ IL-5 cytokine receptor family: from ligand recognition to initiation of signaling.
Published in:
Immunological Reviews, 2012, v. 250, n. 1, p. 277, doi. 10.1111/j.1600-065X.2012.01164.x
By:
- Broughton, Sophie E.;
- Dhagat, Urmi;
- Hercus, Timothy R.;
- Nero, Tracy L.;
- Grimbaldeston, Michele A.;
- Bonder, Claudine S.;
- Lopez, Angel F.;
- Parker, Michael W.
Publication type:
Article
Author Correction: EPO does not promote interaction between the erythropoietin and beta-common receptors.
Published in:
2019
By:
- Cheung Tung Shing, Karen S.;
- Broughton, Sophie E.;
- Nero, Tracy L.;
- Gillinder, Kevin;
- Ilsley, Melissa D.;
- Ramshaw, Hayley;
- Lopez, Angel F.;
- Griffin, Michael D. W.;
- Parker, Michael W.;
- Perkins, Andrew C.;
- Dhagat, Urmi
Publication type:
Correction Notice
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 14188, doi. 10.1038/ncomms14188
By:
- Braig, David;
- Nero, Tracy L.;
- Koch, Hans-Georg;
- Kaiser, Benedict;
- Wang, Xiaowei;
- Thiele, Jan R.;
- Morton, Craig J.;
- Zeller, Johannes;
- Kiefer, Jurij;
- Potempa, Lawrence A.;
- Mellett, Natalie A.;
- Miles, Luke A.;
- Du, Xiao-Jun;
- Meikle, Peter J.;
- Huber-Lang, Markus;
- Stark, G. Björn;
- Parker, Michael W.;
- Peter, Karlheinz;
- Eisenhardt, Steffen U.
Publication type:
Article
Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer.
Published in:
Cell Death & Disease, 2024, v. 15, n. 4, p. 1, doi. 10.1038/s41419-024-06631-8
By:
- Dmello, Rhynelle S.;
- Palmieri, Michelle;
- Thilakasiri, Pathum S.;
- Doughty, Larissa;
- Nero, Tracy L.;
- Poh, Ashleigh R.;
- To, Sarah Q.;
- Lee, Erinna F.;
- Douglas Fairlie, W.;
- Mielke, Lisa;
- Parker, Michael W.;
- Poon, Ivan K. H.;
- Batlle, Eduard;
- Ernst, Matthias;
- Chand, Ashwini L.
Publication type:
Article
Protein structure and computational drug discovery.
Published in:
Biochemical Society Transactions, 2018, v. 46, n. 5, p. 1367, doi. 10.1042/BST20180202
By:
- Nero, Tracy L.;
- Parker, Michael W.;
- Morton, Craig J.
Publication type:
Article
Potent hepatitis C inhibitors bind directly to NS5A and reduce its affinity for RNA.
Published in:
Scientific Reports, 2014, p. 1, doi. 10.1038/srep04765
By:
- Ascher, David B.;
- Wielens, Jerome;
- Nero, Tracy L.;
- Doughty, Larissa;
- Morton, Craig J.;
- Parker, Michael W.
Publication type:
Article
A dual role for the N-terminal domain of the IL-3 receptor in cell signalling.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02633-7
By:
- Broughton, Sophie E.;
- Hercus, Timothy R.;
- Nero, Tracy L.;
- Kan, Winnie L.;
- Barry, Emma F.;
- Dottore, Mara;
- Cheung Tung Shing, Karen S.;
- Morton, Craig J.;
- Dhagat, Urmi;
- Hardy, Matthew P.;
- Wilson, Nicholas J.;
- Downton, Matthew T.;
- Schieber, Christine;
- Hughes, Timothy P.;
- Lopez, Angel F.;
- Parker, Michael W.
Publication type:
Article
EPO does not promote interaction between the erythropoietin and beta-common receptors.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-29865-x
By:
- Cheung Tung Shing, Karen S.;
- Broughton, Sophie E.;
- Nero, Tracy L.;
- Gillinder, Kevin;
- Ilsley, Melissa D.;
- Ramshaw, Hayley;
- Lopez, Angel F.;
- Griffin, Michael D. W.;
- Parker, Michael W.;
- Perkins, Andrew C.;
- Dhagat, Urmi
Publication type:
Article
Oncogenic protein interfaces: small molecules, big challenges.
Published in:
Nature Reviews Cancer, 2014, v. 14, n. 4, p. 248, doi. 10.1038/nrc3690
By:
- Nero, Tracy L.;
- Morton, Craig J.;
- Holien, Jessica K.;
- Wielens, Jerome;
- Parker, Michael W.
Publication type:
Article
THE 'Q-BAND' ABSORPTION spECTRA OF HEMATOPORPHYRIN MONOMER AND AGGREGATE IN AQUEOUS SOLUTION.
Published in:
Photochemistry & Photobiology, 1989, v. 49, n. 1, p. 49, doi. 10.1111/j.1751-1097.1989.tb04076.x
By:
- SMITH, GERALD J.;
- GHIGGINO, KENNETH P.;
- BENNETT, LOUISE E.;
- NERO, TRACY L.
Publication type:
Article

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