Works matching AU Nefzi, Adel

Results: 27

Easy Conversion of Dimethyl α -(Bromomethyl)fumarate into Functionalized Allyl Ethers Mediated by DABCO.

Published in:

Synthetic Communications, 2015, v. 45, n. 22, p. 2627, doi. 10.1080/00397911.2015.1093144

By:

Arfaoui, Aïcha;
Saâdi, Fatma;
Nefzi, Adel;
Amri, Hassen

Publication type:

Article

Synthesis of Diazacyclic and Triazacyclic Small-Molecule Libraries Using Vicinal Chiral Diamines Generated from Modified Short Peptides and Their Application for Drug Discovery.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 12, p. 1566, doi. 10.3390/ph17121566

By:

Tantak, Mukund P.;
Rayala, Ramanjaneyulu;
Chaudhari, Prakash;
Danta, Chhanda C.;
Nefzi, Adel

Publication type:

Article

Integrating computational and mixture-based screening of combinatorial libraries.

Published in:

Journal of Molecular Modeling, 2011, v. 17, n. 6, p. 1473, doi. 10.1007/s00894-010-0850-1

By:

Yongye, Austin B.;
Pinilla, Clemencia;
Medina-Franco, Jose L.;
Giulianotti, Marc A.;
Dooley, Colette T.;
Appel, Jon R.;
Nefzi, Adel;
Scior, Thomas;
Houghten, Richard A.;
Martínez-Mayorga, Karina

Publication type:

Article

Potential therapeutic use of dermaseptin S4 from the frog Phyllomedusa sauvagii and its derivatives against bacterial pathogens in fish.

Published in:

Journal of Applied Microbiology, 2024, v. 135, n. 9, p. 1, doi. 10.1093/jambio/lxae222

By:

Braik, Afef;
Serna-Duque, John Alberto;
Nefzi, Adel;
Aroui, Sonia;
Esteban, María Ángeles

Publication type:

Article

Parallel Synthesis of Piperazine Tethered Thiazole Compounds with Antiplasmodial Activity.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 24, p. 17414, doi. 10.3390/ijms242417414

By:

Rayala, Ramanjaneyulu;
Chaudhari, Prakash;
Bunnell, Ashley;
Roberts, Bracken;
Chakrabarti, Debopam;
Nefzi, Adel

Publication type:

Article

Bis-Cyclic Guanidine Heterocyclic Peptidomimetics as Opioid Ligands with Mixed μ-, κ- and δ-Opioid Receptor Interactions: A Potential Approach to Novel Analgesics.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 17, p. 9623, doi. 10.3390/ijms23179623

By:

McLaughlin, Jay P.;
Rayala, Ramanjaneyulu;
Bunnell, Ashley J.;
Tantak, Mukund P.;
Eans, Shainnel O.;
Nefzi, Khadija;
Ganno, Michelle L.;
Dooley, Colette T.;
Nefzi, Adel

Publication type:

Article

1,5-Disubstituted Acylated 2-Amino-4,5-dihydroimidazoles as a New Class of Retinoic Acid Receptor–Related Orphan Receptor (ROR) Inhibitors.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 8, p. 4433, doi. 10.3390/ijms23084433

By:

Ortiz, Maria A.;
Piedrafita, F. Javier;
Nefzi, Adel

Publication type:

Article

Small Molecule Compounds Identified from Mixture-Based Library Inhibit Binding between Plasmodium falciparum Infected Erythrocytes and Endothelial Receptor ICAM-1.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 5659, doi. 10.3390/ijms22115659

By:

Chesnokov, Olga;
Visitdesotrakul, Pimnitah;
Kalani, Komal;
Nefzi, Adel;
Oleinikov, Andrew V.

Publication type:

Article

Conformational landscape of platinum(II)-tetraamine complexes: DFT and NBO studies.

Published in:

Journal of Computer-Aided Molecular Design, 2010, v. 24, n. 3, p. 225, doi. 10.1007/s10822-010-9328-6

By:

Yongye, Austin B.;
Giulianotti, Marc A.;
Nefzi, Adel;
Houghten, Richard A.;
Martínez-Mayorga, Karina

Publication type:

Article

Solid phase synthesis of mixture-based acyclic and heterocyclic small molecule combinatorial libraries from resin-bound polyamides.

Published in:

Biopolymers, 2001, v. 60, n. 3, p. 212, doi. 10.1002/1097-0282(2001)60:3<212::AID-BIP10033>3.0.CO;2-D

By:

Nefzi, Adel;
Ostresh, John M.;
Houghten, Richard A.

Publication type:

Article

Identification of Two Novel, Potent, Low-Liability Antinociceptive Compounds from the Direct In Vivo Screening of a Large Mixture-Based Combinatorial Library.

Published in:

AAPS Journal, 2010, v. 12, n. 3, p. 318, doi. 10.1208/s12248-010-9191-3

By:

Reilley, Kate;
Giulianotti, Marc;
Dooley, Colette;
Nefzi, Adel;
McLaughlin, Jay;
Houghten, Richard

Publication type:

Article

Combinatorial library discovery of small molecule inhibitors of lung cancer proliferation and parathyroid hormone-related protein expression.

Published in:

Cancer Biology & Therapy, 2010, v. 10, n. 10, p. 1067, doi. 10.4161/cbt.10.10.13374

By:

Hastings, Randolph H.;
Burton, Douglas W.;
Nefzi, Adel;
Montgrain, Philippe R.;
Quintana, Rick;
Deftos, Leonard J.

Publication type:

Article

Inhibition of methicillin-resistant Staphylococcus aureus (MRSA) by antimicrobial peptides (AMPs) and plant essential oils.

Published in:

Pharmaceutical Biology, 2016, v. 54, n. 12, p. 3136, doi. 10.1080/13880209.2016.1190763

By:

Zouhir, Abdelmajid;
Jridi, Taoufik;
Nefzi, Adel;
Ben Hamida, Jeannette;
Sebei, Khaled

Publication type:

Article

ANTISTAPHYBASE: database of antimicrobial peptides (AMPs) and essential oils (EOs) against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus.

Published in:

Archives of Microbiology, 2017, v. 199, n. 2, p. 215, doi. 10.1007/s00203-016-1293-6

By:

Zouhir, Abdelmajid;
Taieb, Malek;
Lamine, Mohamed;
Cherif, Ammar;
Jridi, Taoufik;
Mahjoubi, Basma;
Mbarek, Sarra;
Fliss, Ismail;
Nefzi, Adel;
Sebei, Khaled;
Ben Hamida, Jeannette

Publication type:

Article

Encoding mu-opioid receptor biased agonism with interaction fingerprints.

Published in:

Journal of Computer-Aided Molecular Design, 2021, v. 35, n. 11, p. 1081, doi. 10.1007/s10822-021-00422-5

By:

Hernández-Alvarado, R. Bruno;
Madariaga-Mazón, Abraham;
Cosme-Vela, Fernando;
Marmolejo-Valencia, Andrés F.;
Nefzi, Adel;
Martinez-Mayorga, Karina

Publication type:

Article

Potent antimicrobial small molecules screened as inhibitors of tyrosine recombinases and Holliday junction-resolving enzymes.

Published in:

Molecular Diversity, 2011, v. 15, n. 4, p. 989, doi. 10.1007/s11030-011-9333-2

By:

Rideout, Marc;
Boldt, Jeffrey;
Vahi-Ferguson, Gabriel;
Salamon, Peter;
Nefzi, Adel;
Ostresh, John;
Giulianotti, Marc;
Pinilla, Clemencia;
Segall, Anca

Publication type:

Article

Editorial: Inflammaging and immunosenescence: role in aging-associated cardiovascular diseases.

Published in:

2025

By:

Barhoumi, Tlili;
Bouchareb, Rihab;
Alroqi, Fayhan;
Nefzi, Adel;
Todryk, Stephen

Publication type:

Editorial

Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine.

Published in:

BMC Medicine, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1741-7015-11-81

By:

Hayes, Crystal D.;
Dey, Debleena;
Palavicini, Juan Pablo;
Wang, Hongjie;
Patkar, Kshitij A.;
Minond, Dimitriy;
Nefzi, Adel;
Lakshmana, Madepalli K.

Publication type:

Article

Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine.

Published in:

2013

By:

Hayes, Crystal D;
Dey, Debleena;
Palavicini, Juan Pablo;
Wang, Hongjie;
Patkar, Kshitij A;
Minond, Dimitriy;
Nefzi, Adel;
Lakshmana, Madepalli K

Publication type:

journal article

Evaluating the effect of dermaseptin S4 and its derivatives on multidrug-resistant bacterial strains and on the colon cancer cell line SW620.

Published in:

Environmental Science & Pollution Research, 2021, v. 28, n. 30, p. 40908, doi. 10.1007/s11356-021-13683-2

By:

Belaid, Afifa;
Braiek, Afef;
Alibi, Sana;
Hassen, Wafa;
Beltifa, Asma;
Nefzi, Adel;
Mansour, Hedi Ben

Publication type:

Article

Discovery and Computational Analyses of Novel Small Molecule Zika Virus Inhibitors.

Published in:

Molecules, 2019, v. 24, n. 8, p. 1465, doi. 10.3390/molecules24081465

By:

Zhu, Siyu;
Zhang, Chaozai;
Huang, Lina S.;
Zhang, Xing-Quan;
Xu, Yan;
Fang, Xiong;
Zhou, Jiao;
Wu, Meixian;
Schooley, Robert T.;
Huang, Ziwei;
An, Jing;
Nefzi, Adel

Publication type:

Article

Identification of Bis-Cyclic Guanidines as Antiplasmodial Compounds from Positional Scanning Mixture-Based Libraries.

Published in:

Molecules, 2019, v. 24, n. 6, p. 1100, doi. 10.3390/molecules24061100

By:

Perry, David L.;
Roberts, Bracken F.;
Debevec, Ginamarie;
Michaels, Heather A.;
Chakrabarti, Debopam;
Nefzi, Adel;
McPhee, Derek J.

Publication type:

Article

Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO-1) Inhibitors Based on Ortho-Naphthaquinone-Containing Natural Product.

Published in:

Molecules, 2019, v. 24, n. 6, p. 1059, doi. 10.3390/molecules24061059

By:

Zhao, Hongchuan;
Sun, Pu;
Guo, Wei;
Wang, Yi;
Zhang, Ao;
Meng, Linghua;
Ding, Chunyong;
Nefzi, Adel

Publication type:

Article

Selective Targeting of the Interconversion between Glucosylceramide and Ceramide by Scaffold Tailoring of Iminosugar Inhibitors.

Published in:

Molecules, 2019, v. 24, n. 2, p. 354, doi. 10.3390/molecules24020354

By:

Baudoin-Dehoux, Cécile;
Castellan, Tessa;
Rodriguez, Frédéric;
Rives, Arnaud;
Stauffert, Fabien;
Garcia, Virginie;
Levade, Thierry;
Compain, Philippe;
Génisson, Yves;
Nefzi, Adel

Publication type:

Article

Neo-5,22E-Cholestadienol Derivatives from Buthus martensii Karsch and Targeted Bactericidal Action Mechanisms.

Published in:

Molecules, 2019, v. 24, n. 1, p. 72, doi. 10.3390/molecules24010072

By:

Lv, Biyu;
Yin, Weiping;
Gao, Jiayu;
Liu, Huaqing;
Liu, Kun;
Bai, Jie;
Yang, Qiangqiang;
Nefzi, Adel

Publication type:

Article

Prediction of the experimental regioselectivity of C60 fullerene bis-adducts Prediction of the experimental regioselectivity of C60 fullerene bis-adducts.

Published in:

Journal of Physical Organic Chemistry, 2012, v. 25, n. 11, p. 894, doi. 10.1002/poc.2943

By:

Chaker, Leila;
Yongye, Austin B.;
Nefzi, Adel;
Martínez‐Mayorga, Karina

Publication type:

Article

Increased Diversity of Libraries from Libraries: Chemoinformatic Analysis of Bis-Diazacyclic Libraries.

Published in:

Chemical Biology & Drug Design, 2011, v. 77, n. 5, p. 328, doi. 10.1111/j.1747-0285.2011.01100.x

By:

López-Vallejo, Fabian;
Nefzi, Adel;
Bender, Andreas;
Owen, John R.;
Nabney, Ian T.;
Houghten, Richard A.;
Medina-Franco, José L.

Publication type:

Article

Works matching AU Nefzi, Adel

Easy Conversion of Dimethyl α -(Bromomethyl)fumarate into Functionalized Allyl Ethers Mediated by DABCO.

Synthesis of Diazacyclic and Triazacyclic Small-Molecule Libraries Using Vicinal Chiral Diamines Generated from Modified Short Peptides and Their Application for Drug Discovery.

Integrating computational and mixture-based screening of combinatorial libraries.

Potential therapeutic use of dermaseptin S<sub>4</sub> from the frog Phyllomedusa sauvagii and its derivatives against bacterial pathogens in fish.

Parallel Synthesis of Piperazine Tethered Thiazole Compounds with Antiplasmodial Activity.

Bis-Cyclic Guanidine Heterocyclic Peptidomimetics as Opioid Ligands with Mixed μ-, κ- and δ-Opioid Receptor Interactions: A Potential Approach to Novel Analgesics.

1,5-Disubstituted Acylated 2-Amino-4,5-dihydroimidazoles as a New Class of Retinoic Acid Receptor–Related Orphan Receptor (ROR) Inhibitors.

Small Molecule Compounds Identified from Mixture-Based Library Inhibit Binding between Plasmodium falciparum Infected Erythrocytes and Endothelial Receptor ICAM-1.

Conformational landscape of platinum(II)-tetraamine complexes: DFT and NBO studies.

Solid phase synthesis of mixture-based acyclic and heterocyclic small molecule combinatorial libraries from resin-bound polyamides.

Identification of Two Novel, Potent, Low-Liability Antinociceptive Compounds from the Direct In Vivo Screening of a Large Mixture-Based Combinatorial Library.

Combinatorial library discovery of small molecule inhibitors of lung cancer proliferation and parathyroid hormone-related protein expression.

Inhibition of methicillin-resistant Staphylococcus aureus (MRSA) by antimicrobial peptides (AMPs) and plant essential oils.

ANTISTAPHYBASE: database of antimicrobial peptides (AMPs) and essential oils (EOs) against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus.

Encoding mu-opioid receptor biased agonism with interaction fingerprints.

Potent antimicrobial small molecules screened as inhibitors of tyrosine recombinases and Holliday junction-resolving enzymes.

Editorial: Inflammaging and immunosenescence: role in aging-associated cardiovascular diseases.

Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine.

Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine.

Evaluating the effect of dermaseptin S4 and its derivatives on multidrug-resistant bacterial strains and on the colon cancer cell line SW620.

Discovery and Computational Analyses of Novel Small Molecule Zika Virus Inhibitors.

Identification of Bis-Cyclic Guanidines as Antiplasmodial Compounds from Positional Scanning Mixture-Based Libraries.

Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO-1) Inhibitors Based on Ortho-Naphthaquinone-Containing Natural Product.

Selective Targeting of the Interconversion between Glucosylceramide and Ceramide by Scaffold Tailoring of Iminosugar Inhibitors.

Neo-5,22E-Cholestadienol Derivatives from Buthus martensii Karsch and Targeted Bactericidal Action Mechanisms.

Prediction of the experimental regioselectivity of C<sub>60</sub> fullerene bis-adducts Prediction of the experimental regioselectivity of C<sub>60</sub> fullerene bis-adducts.

Increased Diversity of Libraries from Libraries: Chemoinformatic Analysis of Bis-Diazacyclic Libraries.