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High ploidy large cytoplasmic megakaryocytes are hematopoietic stem cells regulators and essential for platelet production.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37780-7
By:
- Heazlewood, Shen Y.;
- Ahmad, Tanveer;
- Cao, Benjamin;
- Cao, Huimin;
- Domingues, Melanie;
- Sun, Xuan;
- Heazlewood, Chad K.;
- Li, Songhui;
- Williams, Brenda;
- Fulton, Madeline;
- White, Jacinta F.;
- Nebl, Tom;
- Nefzger, Christian M.;
- Polo, Jose M.;
- Kile, Benjamin T.;
- Kraus, Felix;
- Ryan, Michael T.;
- Sun, Yu B.;
- Choong, Peter F. M.;
- Ellis, Sarah L.
Publication type:
Article
Retrotransposon instability dominates the acquired mutation landscape of mouse induced pluripotent stem cells.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35180-x
By:
- Gerdes, Patricia;
- Lim, Sue Mei;
- Ewing, Adam D.;
- Larcombe, Michael R.;
- Chan, Dorothy;
- Sanchez-Luque, Francisco J.;
- Walker, Lucinda;
- Carleton, Alexander L.;
- James, Cini;
- Knaupp, Anja S.;
- Carreira, Patricia E.;
- Nefzger, Christian M.;
- Lister, Ryan;
- Richardson, Sandra R.;
- Polo, Jose M.;
- Faulkner, Geoffrey J.
Publication type:
Article
BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29333-1
By:
- Keniry, Andrew;
- Jansz, Natasha;
- Gearing, Linden J.;
- Wanigasuriya, Iromi;
- Chen, Joseph;
- Nefzger, Christian M.;
- Hickey, Peter F.;
- Gouil, Quentin;
- Liu, Joy;
- Breslin, Kelsey A.;
- Iminitoff, Megan;
- Beck, Tamara;
- Tapia del Fierro, Andres;
- Whitehead, Lachlan;
- Jarratt, Andrew;
- Kinkel, Sarah A.;
- Taberlay, Phillippa C.;
- Willson, Tracy;
- Pakusch, Miha;
- Ritchie, Matthew E.
Publication type:
Article
Breaking constraint of mammalian axial formulae.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-021-27335-z
By:
- Hauswirth, Gabriel M.;
- Garside, Victoria C.;
- Wong, Lisa S. F.;
- Bildsoe, Heidi;
- Manent, Jan;
- Chang, Yi-Cheng;
- Nefzger, Christian M.;
- Firas, Jaber;
- Chen, Joseph;
- Rossello, Fernando J.;
- Polo, Jose M.;
- McGlinn, Edwina
Publication type:
Article
Mitochondrial DNA Haplotypes Define Gene Expression Patterns in Pluripotent and Differentiating Embryonic Stem Cells.
Published in:
Stem Cells, 2013, v. 31, n. 4, p. 703, doi. 10.1002/stem.1313
By:
- KELLY, RICHARD D. W.;
- RODDA, ANDREW E.;
- DICKINSON, ADAM;
- MAHMUD, ARSALAN;
- NEFZGER, CHRISTIAN M.;
- LEE, WILLIAM;
- FORSYTHE, JOHN S.;
- POLO, JOSE M.;
- TROUNCE, IAN A.;
- MCKENZIE, MATTHEW;
- NISBET, DAVID R.;
- ST. JOHN, JUSTIN C.
Publication type:
Article
Lmx1a Allows Context-Specific Isolation of Progenitors of GABAergic or Dopaminergic Neurons During Neural Differentiation of Embryonic Stem Cells.
Published in:
Stem Cells, 2012, v. 30, n. 7, p. 1349, doi. 10.1002/stem.1105
By:
- Nefzger, Christian M.;
- Su, Colin T.;
- Fabb, Stewart A.;
- Hartley, Brigham J.;
- Beh, Siew J.;
- Zeng, Wendy R.;
- Haynes, John M.;
- Pouton, Colin W.
Publication type:
Article
Directed Expression of Gata2, Mash1, and Foxa2 Synergize to Induce the Serotonergic Neuron Phenotype During In Vitro Differentiation of Embryonic Stem Cells.
Published in:
Stem Cells, 2011, v. 29, n. 6, p. 928, doi. 10.1002/stem.640
By:
- NEFZGER, CHRISTIAN M.;
- HAYNES, JOHN M.;
- POUTON, COLIN W.
Publication type:
Article
Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium.
Published in:
EMBO Journal, 2015, v. 34, n. 10, p. 1319, doi. 10.15252/embj.201490881
By:
- Horvay, Katja;
- Jardé, Thierry;
- Casagranda, Franca;
- Perreau, Victoria M;
- Haigh, Katharina;
- Nefzger, Christian M;
- Akhtar, Reyhan;
- Gridley, Thomas;
- Berx, Geert;
- Haigh, Jody J;
- Barker, Nick;
- Polo, Jose M;
- Hime, Gary R;
- Abud, Helen E
Publication type:
Article
Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity.
Published in:
PLoS Biology, 2021, v. 19, n. 9, p. 1, doi. 10.1371/journal.pbio.3001394
By:
- Wang, Jueqiong;
- Farkas, Carlos;
- Benyoucef, Aissa;
- Carmichael, Catherine;
- Haigh, Katharina;
- Wong, Nick;
- Huylebroeck, Danny;
- Stemmler, Marc P.;
- Brabletz, Simone;
- Brabletz, Thomas;
- Nefzger, Christian M.;
- Goossens, Steven;
- Berx, Geert;
- Polo, Jose M.;
- Haigh, Jody J.
Publication type:
Article
Probing transcription factor diffusion dynamics in the living mammalian embryo with photoactivatable fluorescence correlation spectroscopy.
Published in:
Nature Communications, 2013, v. 4, n. 3, p. 1637, doi. 10.1038/ncomms2657
By:
- Kaur, Gurpreet;
- Costa, Mauro W.;
- Nefzger, Christian M.;
- Silva, Juan;
- Fierro-González, Juan Carlos;
- Polo, Jose M.;
- Bell, Toby D.M.;
- Plachta, Nicolas
Publication type:
Article
Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release.
Published in:
Science Signaling, 2023, v. 16, n. 782, p. 1, doi. 10.1126/scisignal.abq1366
By:
- Labzin, Larisa I.;
- Chew, Keng Yih;
- Eschke, Kathrin;
- Wang, Xiaohui;
- Esposito, Tyron;
- Stocks, Claudia J.;
- Rae, James;
- Patrick, Ralph;
- Mostafavi, Helen;
- Hill, Brittany;
- Yordanov, Teodor E.;
- Holley, Caroline L.;
- Emming, Stefan;
- Fritzlar, Svenja;
- Mordant, Francesca L.;
- Steinfort, Daniel P.;
- Subbarao, Kanta;
- Nefzger, Christian M.;
- Lagendijk, Anne K.;
- Gordon, Emma J.
Publication type:
Article
Organization of gene programs revealed by unsupervised analysis of diverse gene–trait associations.
Published in:
Nucleic Acids Research, 2022, v. 50, n. 15, p. e87, doi. 10.1093/nar/gkac413
By:
- Mizikovsky, Dalia;
- Naval Sanchez, Marina;
- Nefzger, Christian M;
- Cuellar Partida, Gabriel;
- Palpant, Nathan J
Publication type:
Article
Identification of dynamic undifferentiated cell states within the male germline.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04827-z
By:
- La, Hue M.;
- Mäkelä, Juho-Antti;
- Ai-Leen Chan;
- Rossello, Fernando J.;
- Nefzger, Christian M.;
- Legrand, Julien M. D.;
- De Seram, Mia;
- Polo, Jose M.;
- Hobbs, Robin M.
Publication type:
Article
Intestinal stem cell aging signature reveals a reprogramming strategy to enhance regenerative potential.
Published in:
NPJ Regenerative Medicine, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41536-022-00226-7
By:
- Nefzger, Christian M.;
- Jardé, Thierry;
- Srivastava, Akanksha;
- Schroeder, Jan;
- Rossello, Fernando J.;
- Horvay, Katja;
- Prasko, Mirsada;
- Paynter, Jacob M.;
- Chen, Joseph;
- Weng, Chen-Fang;
- Sun, Yu B. Y.;
- Liu, Xiaodong;
- Chan, Eva;
- Deshpande, Nikita;
- Chen, Xiaoli;
- Li, Y. Jinhua;
- Pflueger, Jahnvi;
- Engel, Rebekah M.;
- Knaupp, Anja S.;
- Tsyganov, Kirill
Publication type:
Article

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