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Structural basis of a redox-dependent conformational switch that regulates the stress kinase p38α.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43763-5
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- Article
Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39051-x
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- Article
Synthesis and Biological Activity of a VHL-Based PROTAC Specific for p38α.
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- Cancers, 2023, v. 15, n. 3, p. 611, doi. 10.3390/cancers15030611
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- Article
Stress signaling boosts interferon-induced gene transcription in macrophages.
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- Science Signaling, 2022, v. 15, n. 764, p. 1, doi. 10.1126/scisignal.abq5389
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- Article
Macrophage inflammation resolution requires CPEB4-directed offsetting of mRNA degradation.
- Published in:
- eLife, 2022, p. 1, doi. 10.7554/eLife.75873
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- Article
IκBα deficiency imposes a fetal phenotype to intestinal stem cells.
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- EMBO Reports, 2020, v. 21, n. 6, p. 1, doi. 10.15252/embr.201949708
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- Article
A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia.
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- Blood Cancer Journal, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41408-019-0270-0
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- Publication type:
- Article
Neuronal p38α mediates age‐associated neural stem cell exhaustion and cognitive decline.
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- Aging Cell, 2019, v. 18, n. 6, p. N.PAG, doi. 10.1111/acel.13044
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- Article
Author Correction: Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor.
- Published in:
- 2019
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- Correction Notice
Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11594-y
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- Publication type:
- Article
Regulation of tumor angiogenesis and mesenchymal–endothelial transition by p38α through TGF-β and JNK signaling.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10946-y
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- Publication type:
- Article
Regulation of tumor angiogenesis and mesenchymal–endothelial transition by p38α through TGF-β and JNK signaling.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10946-y
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- Publication type:
- Article
Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10830-9
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- Publication type:
- Article
Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism.
- Published in:
- Frontiers in Neurology, 2019, p. N.PAG, doi. 10.3389/fneur.2019.00675
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- Publication type:
- Article
Autophagy-induced senescence is regulated by p38α signaling.
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- Cell Death & Disease, 2019, v. 10, n. 6, p. N.PAG, doi. 10.1038/s41419-019-1607-0
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- Article
Regulation of death receptor signaling by the autophagy protein TP53INP2.
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- EMBO Journal, 2019, v. 38, n. 10, p. N.PAG, doi. 10.15252/embj.201899300
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- Article
P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05955-2
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- Publication type:
- Article
p38α blocks brown adipose tissue thermogenesis through p38δ inhibition.
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- PLoS Biology, 2018, p. 1, doi. 10.1371/journal.pbio.2004455
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- Article
Myeloid p38α signaling promotes intestinal IGF‐1 production and inflammation‐associated tumorigenesis.
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- EMBO Molecular Medicine, 2018, v. 10, n. 7, p. 1, doi. 10.15252/emmm.201708403
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- Publication type:
- Article
p38α regulates cytokine-induced IFNγ secretion via the Mnk1/eIF4E pathway in Th1 cells.
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- Immunology & Cell Biology, 2017, v. 95, n. 9, p. 814, doi. 10.1038/icb.2017.51
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- Publication type:
- Article
Changes in the free-energy landscape of p38α MAP kinase through its canonical activation and binding events as studied by enhanced molecular dynamics simulations.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.22175.001
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- Publication type:
- Article
Neuronal p38α mediates synaptic and cognitive dysfunction in an Alzheimer's mouse model by controlling β-amyloid production.
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- Scientific Reports, 2017, p. 45306, doi. 10.1038/srep45306
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- Publication type:
- Article
p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging.
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- PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0171738
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- Article
Essential role of the Cdk2 activator RingoA in meiotic telomere tethering to the nuclear envelope.
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- Nature Communications, 2016, v. 7, n. 3, p. 11084, doi. 10.1038/ncomms11084
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- Article
Oxidative Stress Is a Central Target for Physical Exercise Neuroprotection Against Pathological Brain Aging.
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- 2016
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- Publication type:
- journal article
Roles of p38α mitogen-activated protein kinase in mouse models of inflammatory diseases and cancer.
- Published in:
- FEBS Journal, 2015, v. 282, n. 10, p. 1841, doi. 10.1111/febs.13250
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- Publication type:
- Article
Roles of p38α mitogen-activated protein kinase in mouse models of inflammatory diseases and cancer.
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- FEBS Journal, 2015, v. 282, n. 9, p. 1841, doi. 10.1111/febs.13250
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- Publication type:
- Article
Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH.
- Published in:
- Nature Cell Biology, 2014, v. 16, n. 7, p. 685, doi. 10.1038/ncb2977
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- Publication type:
- Article
Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK.
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- EMBO Molecular Medicine, 2013, v. 5, n. 11, p. 1759, doi. 10.1002/emmm.201302732
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- Publication type:
- Article
Cover Picture: Multi-phosphorylation of the Intrinsically Disordered Unique Domain of c-Src Studied by In-Cell and Real-Time NMR Spectroscopy (ChemBioChem 14/2013).
- Published in:
- ChemBioChem, 2013, v. 14, n. 14, p. 1669, doi. 10.1002/cbic.201390050
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- Publication type:
- Article
Multi-phosphorylation of the Intrinsically Disordered Unique Domain of c-Src Studied by In-Cell and Real-Time NMR Spectroscopy.
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- ChemBioChem, 2013, v. 14, n. 14, p. 1820, doi. 10.1002/cbic.201300139
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- Publication type:
- Article
The p57 CDKi integrates stress signals into cell-cycle progression to promote cell survival upon stress.
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- EMBO Journal, 2012, v. 31, n. 13, p. 2952, doi. 10.1038/emboj.2012.122
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- Article
Essential role of p18<sup>Hamlet</sup>/SRCAP-mediated histone H2A.Z chromatin incorporation in muscle differentiation.
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- EMBO Journal, 2010, v. 29, n. 12, p. 2014, doi. 10.1038/emboj.2010.85
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- Publication type:
- Article
UV-induced downregulation of the CDC25B protein in human cells
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- FEBS Letters, 2010, v. 584, n. 6, p. 1199, doi. 10.1016/j.febslet.2010.02.043
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- Article
Whole genome analysis of p38 SAPK-mediatedgene expression upon stress.
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- BMC Genomics, 2010, v. 11, p. 144, doi. 10.1186/1471-2164-11-144
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- Publication type:
- Article
Cell cycle regulation of the mammalian CDK activator RINGO/Speedy A
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- FEBS Letters, 2009, v. 583, n. 17, p. 2772, doi. 10.1016/j.febslet.2009.07.028
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- Article
Signal integration by JNK and p38 MAPK pathways in cancer development.
- Published in:
- 2009
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- Publication type:
- journal article
p38α MAPK inhibits JNK activation and collaborates with IκB kinase 2 to prevent endotoxin-induced liver failure.
- Published in:
- EMBO Reports, 2008, v. 9, n. 10, p. 1048, doi. 10.1038/embor.2008.149
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- Publication type:
- Article
p38α MAPK can positively or negatively regulate Rac-1 activity depending on the presence of serum
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- FEBS Letters, 2007, v. 581, n. 20, p. 3819, doi. 10.1016/j.febslet.2007.06.078
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- Publication type:
- Article
A combination of neutral loss and targeted product ion scanning with two enzymatic digestions facilitates the comprehensive mapping of phosphorylation sites.
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- Proteomics, 2007, v. 7, n. 15, p. 2522, doi. 10.1002/pmic.200700026
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- Publication type:
- Article
p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation.
- Published in:
- Nature Genetics, 2007, v. 39, n. 6, p. 750, doi. 10.1038/ng2037
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- Article
A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis.
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- EMBO Journal, 2007, v. 26, n. 8, p. 2115, doi. 10.1038/sj.emboj.7601657
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- Publication type:
- Article
Meiotic regulation of the CDK activator RINGO/Speedy by ubiquitin-proteasome-mediated processing and degradation.
- Published in:
- Nature Cell Biology, 2006, v. 8, n. 10, p. 1084, doi. 10.1038/ncb1472
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- Publication type:
- Article
Proteomic analysis of p38α mitogen-activated protein kinase-regulated changes in membrane fractions of RAS-transformed fibroblasts.
- Published in:
- Proteomics, 2006, v. 6, n. 0, p. S262, doi. 10.1002/pmic.200500350
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- Publication type:
- Article
p38α MAPK is required for contact inhibition.
- Published in:
- Oncogene, 2005, v. 24, n. 53, p. 7941, doi. 10.1038/sj.onc.1208948
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- Publication type:
- Article
Phosphorylation of EEA1 by p38 MAP kinase regulates μ opioid receptor endocytosis.
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- EMBO Journal, 2005, v. 24, n. 18, p. 3235, doi. 10.1038/sj.emboj.7600799
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- Publication type:
- Article
Phosphorylation of MRF4 transactivation domain by p38 mediates repression of specific myogenic genes.
- Published in:
- EMBO Journal, 2004, v. 23, n. 2, p. 365, doi. 10.1038/sj.emboj.7600056
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- Publication type:
- Article
Xp38γ/SAPK3 promotes meiotic G<sub>2</sub>/M transition in Xenopus oocytes and activates Cdc25C.
- Published in:
- EMBO Journal, 2003, v. 22, n. 21, p. 5746, doi. 10.1093/emboj/cdg559
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- Publication type:
- Article
Feedback control of the protein kinase TAK1 by SAPK2a/p38α.
- Published in:
- EMBO Journal, 2003, v. 22, n. 21, p. 5793, doi. 10.1093/emboj/cdg552
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- Publication type:
- Article
Xkid chromokinesin is required for the meiosis I to meiosis II transition in Xenopus laevis oocytes.
- Published in:
- Nature Cell Biology, 2002, v. 4, n. 10, p. 737, doi. 10.1038/ncb850
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- Publication type:
- Article