Works matching AU Nazio, Francesca

Results: 31

Medulloblastoma: Molecular Targets and Innovative Theranostic Approaches.

Published in:

Pharmaceutics, 2025, v. 17, n. 6, p. 736, doi. 10.3390/pharmaceutics17060736

By:

Foti, Alice;
Allia, Fabio;
Briglia, Marilena;
Malaguarnera, Roberta;
Tamburrini, Gianpiero;
Cecconi, Francesco;
Pagliarini, Vittoria;
Nazio, Francesca;
Graziano, Adriana Carol Eleonora

Publication type:

Article

TFG: a novel regulator of ULK1-dependent autophagy.

Published in:

Molecular & Cellular Oncology, 2021, v. 8, n. 4, p. 1, doi. 10.1080/23723556.2021.1945895

By:

Cecconi, Francesco;
Nazio, Francesca

Publication type:

Article

Zebrafish ambra1b knockout reveals a novel role for Ambra1 in primordial germ cells survival, sex differentiation and reproduction.

Published in:

Biological Research, 2023, v. 56, n. 1, p. 1, doi. 10.1186/s40659-023-00430-9

By:

Fontana, Camilla Maria;
Terrin, Francesca;
Facchinello, Nicola;
Meneghetti, Giacomo;
Dinarello, Alberto;
Gambarotto, Lisa;
Zuccarotto, Annalisa;
Caichiolo, Micol;
Brocca, Ginevra;
Verin, Ranieri;
Nazio, Francesca;
Carnevali, Oliana;
Cecconi, Francesco;
Bonaldo, Paolo;
Dalla Valle, Luisa

Publication type:

Article

Rapamycin and fasting sustain autophagy response activated by ischemia/reperfusion injury and promote retinal ganglion cell survival.

Published in:

Cell Death & Disease, 2018, v. 9, n. 10, p. 1, doi. 10.1038/s41419-018-1044-5

By:

Russo, Rossella;
Varano, Giuseppe Pasquale;
Adornetto, Annagrazia;
Nazio, Francesca;
Tettamanti, Gianluca;
Girardello, Rossana;
Cianfanelli, Valentina;
Cavaliere, Federica;
Morrone, Luigi Antonio;
Corasaniti, Maria Tiziana;
Cecconi, Francesco;
Bagetta, Giacinto;
Nucci, Carlo

Publication type:

Article

Effects of caloric restriction on neuropathic pain, peripheral nerve degeneration and inflammation in normometabolic and autophagy defective prediabetic Ambra1 mice.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0208596

By:

Coccurello, Roberto;
Nazio, Francesca;
Rossi, Claudia;
De Angelis, Federica;
Vacca, Valentina;
Giacovazzo, Giacomo;
Procacci, Patrizia;
Magnaghi, Valerio;
Ciavardelli, Domenico;
Marinelli, Sara

Publication type:

Article

The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy.

Published in:

Journal of Cell Biology, 2010, v. 191, n. 1, p. 155, doi. 10.1083/jcb.201002100

By:

Di Bartolomeo, Sabrina;
Corazzari, Marco;
Nazio, Francesca;
Oliverio, Serafina;
Lisi, Gaia;
Antonioli, Manuela;
Pagliarini, Vittoria;
Matteoni, Silvia;
Fuoco, Claudia;
Giunta, Luigi;
D'Amelio, Marcello;
Nardacci, Roberta;
Romagnoli, Alessandra;
Piacentini, Mauro;
Cecconi, Francesco;
Fimia, Gian Maria

Publication type:

Article

Autophagy up and down by outsmarting the incredible ULK.

Published in:

Autophagy, 2017, v. 13, n. 5, p. 967, doi. 10.1080/15548627.2017.1285473

By:

Nazio, Francesca;
Cecconi, Francesco

Publication type:

Article

Prosurvival AMBRA1 turns into a proapoptotic BH3-like protein during mitochondrial apoptosis.

Published in:

Autophagy, 2016, v. 12, n. 6, p. 963, doi. 10.1080/15548627.2016.1164359

By:

Strappazzon, Flavie;
Di Rita, Anthea;
Cianfanelli, Valentina;
D'Orazio, Melania;
Nazio, Francesca;
Fimia, Gian Maria;
Cecconi, Francesco

Publication type:

Article

Canonical and Noncanonical Roles of Fanconi Anemia Proteins: Implications in Cancer Predisposition.

Published in:

Cancers, 2020, v. 12, n. 9, p. 2684, doi. 10.3390/cancers12092684

By:

Milletti, Giacomo;
Strocchio, Luisa;
Pagliara, Daria;
Girardi, Katia;
Carta, Roberto;
Mastronuzzi, Angela;
Locatelli, Franco;
Nazio, Francesca

Publication type:

Article

ULK1 ubiquitylation is regulated by phosphorylation on its carboxy terminus.

Published in:

Cell Cycle, 2017, v. 16, n. 19, p. 1744, doi. 10.1080/15384101.2017.1361063

By:

Nazio, Francesca;
Carinci, Marianna;
Cecconi, Francesco

Publication type:

Article

mTOR, AMBRA1, and autophagy.

Published in:

Cell Cycle, 2013, v. 12, n. 16, p. 2524, doi. 10.4161/cc.25835

By:

Nazio, Francesca;
Cecconi, Francesco

Publication type:

Article

Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation.

Published in:

Journal of Cell Biology, 2016, v. 215, n. 6, p. 841, doi. 10.1083/jcb.201605089

By:

Nazio, Francesca;
Carinci, Marianna;
Valacca, Cristina;
Bielli, Pamela;
Strappazzon, Flavie;
Antonioli, Manuela;
Ciccosanti, Fabiola;
Rodolfo, Carlo;
Campello, Silvia;
Fimia, Gian Maria;
Sette, Claudio;
Bonaldo, Paolo;
Cecconi, Francesco

Publication type:

Article

The Role of Autophagy During Development in Higher Eukaryotes.

Published in:

Traffic, 2010, v. 11, n. 10, p. 1280, doi. 10.1111/j.1600-0854.2010.01103.x

By:

Di Bartolomeo, Sabrina;
Nazio, Francesca;
Cecconi, Francesco

Publication type:

Article

Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage.

Published in:

Autophagy, 2012, v. 8, n. 2, p. 222, doi. 10.4161/auto.8.2.18599

By:

Viscomi, Maria Teresa;
D'Amelio, Marcello;
Cavallucci, Virve;
Latini, Laura;
Bisicchia, Elisa;
Nazio, Francesca;
Fanelli, Francesca;
Maccarrone, Mauro;
Moreno, Sandra;
Cecconi, Francesco;
Molinari, Marco

Publication type:

Article

Neuroblastoma-secreted exosomes carrying miR‐375 promote osteogenic differentiation of bone-marrow mesenchymal stromal cells.

Published in:

Journal of Extracellular Vesicles, 2020, v. 9, n. 1, p. 1, doi. 10.1080/20013078.2020.1774144

By:

Colletti, Marta;
Tomao, Luigi;
Galardi, Angela;
Paolini, Alessandro;
Di Paolo, Virginia;
De Stefanis, Cristiano;
Mascio, Paolo;
Nazio, Francesca;
Petrini, Stefania;
Castellano, Aurora;
Russo, Ida;
Caruso, Roberta;
Piga, Simone;
De Vito, Rita;
Pascucci, Luisa;
Peinado, Hector;
Masotti, Andrea;
Locatelli, Franco;
Di Giannatale, Angela

Publication type:

Article

Neuroblastoma‐secreted exosomes carrying miR‐375 promote osteogenic differentiation of bone‐marrow mesenchymal stromal cells.

Published in:

Journal of Extracellular Vesicles, 2020, v. 9, n. 1, p. 1, doi. 10.1080/20013078.2020.1774144

By:

Colletti, Marta;
Tomao, Luigi;
Galardi, Angela;
Paolini, Alessandro;
Di Paolo, Virginia;
De Stefanis, Cristiano;
Mascio, Paolo;
Nazio, Francesca;
Petrini, Stefania;
Castellano, Aurora;
Russo, Ida;
Caruso, Roberta;
Piga, Simone;
De Vito, Rita;
Pascucci, Luisa;
Peinado, Hector;
Masotti, Andrea;
Locatelli, Franco;
Di Giannatale, Angela

Publication type:

Article

The Close interconnection between Mitochondrial Dynamics and Mitophagy in Cancer.

Published in:

Frontiers in Oncology, 2017, v. 7, p. 1, doi. 10.3389/fonc.2017.00081

By:

Bordi, Matteo;
Nazio, Francesca;
Campello, Silvia

Publication type:

Article

Recent Advances in Understanding the Role of Autophagy in Paediatric Brain Tumours.

Published in:

Diagnostics (2075-4418), 2021, v. 11, n. 3, p. 481, doi. 10.3390/diagnostics11030481

By:

Gatto, Francesca;
Milletti, Giacomo;
Carai, Andrea;
Mastronuzzi, Angela;
Nazio, Francesca;
Marchetti, Dario

Publication type:

Article

Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12094-9

By:

Holdgaard, Søs Grønbæk;
Cianfanelli, Valentina;
Pupo, Emanuela;
Lambrughi, Matteo;
Lubas, Michal;
Nielsen, Julie C.;
Eibes, Susana;
Maiani, Emiliano;
Harder, Lea M.;
Wesch, Nicole;
Foged, Mads Møller;
Maeda, Kenji;
Nazio, Francesca;
de la Ballina, Laura R.;
Dötsch, Volker;
Brech, Andreas;
Frankel, Lisa B.;
Jäättelä, Marja;
Locatelli, Franco;
Barisic, Marin

Publication type:

Article

Trimetazidine Improves Mitochondrial Dysfunction in SOD1 G93A Cellular Models of Amyotrophic Lateral Sclerosis through Autophagy Activation.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 6, p. 3251, doi. 10.3390/ijms25063251

By:

Salvatori, Illari;
Nesci, Valentina;
Spalloni, Alida;
Marabitti, Veronica;
Muzzi, Maurizio;
Zenuni, Henri;
Scaricamazza, Silvia;
Rosina, Marco;
Fenili, Gianmarco;
Goglia, Mariangela;
Boffa, Laura;
Massa, Roberto;
Moreno, Sandra;
Mercuri, Nicola Biagio;
Nazio, Francesca;
Longone, Patrizia;
Ferri, Alberto;
Valle, Cristiana

Publication type:

Article

Exploiting autophagy balance in T and NK cells as a new strategy to implement adoptive cell therapies.

Published in:

Molecular Cancer, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12943-023-01893-w

By:

Giansanti, Manuela;
Theinert, Tobias;
Boeing, Sarah Katharina;
Haas, Dorothee;
Schlegel, Paul-Gerhardt;
Vacca, Paola;
Nazio, Francesca;
Caruana, Ignazio

Publication type:

Article

Should I stay or should I go? Spatio-temporal control of cellular anchorage by hematopoietic factors orchestrates tumor metastatic cascade.

Published in:

Molecular Cancer, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12943-023-01851-6

By:

Marabitti, Veronica;
Caruana, Ignazio;
Nazio, Francesca

Publication type:

Article

Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling.

Published in:

Acta Neuropathologica, 2021, v. 142, n. 3, p. 537, doi. 10.1007/s00401-021-02347-7

By:

Nazio, Francesca;
Po, Agnese;
Abballe, Luana;
Ballabio, Claudio;
Diomedi Camassei, Francesca;
Bordi, Matteo;
Camera, Antonio;
Caruso, Simona;
Caruana, Ignazio;
Pezzullo, Marco;
Ferraina, Caterina;
Milletti, Giacomo;
Gianesello, Matteo;
Reddel, Sofia;
De Luca, Carmen Dolores;
Ceglie, Donatella;
Marinelli, Sara;
Campello, Silvia;
Papaleo, Elena;
Miele, Evelina

Publication type:

Article

Cancer Predisposition Syndromes and Medulloblastoma in the Molecular Era.

Published in:

Frontiers in Oncology, 2020, v. 11, p. N.PAG, doi. 10.3389/fonc.2020.566822

By:

Carta, Roberto;
Del Baldo, Giada;
Miele, Evelina;
Po, Agnese;
Besharat, Zein Mersini;
Nazio, Francesca;
Colafati, Giovanna Stefania;
Piccirilli, Eleonora;
Agolini, Emanuele;
Rinelli, Martina;
Lodi, Mariachiara;
Cacchione, Antonella;
Carai, Andrea;
Boccuto, Luigi;
Ferretti, Elisabetta;
Locatelli, Franco;
Mastronuzzi, Angela

Publication type:

Article

Corrigendum: AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation.

Published in:

Nature Cell Biology, 2015, v. 17, n. 5, p. 706, doi. 10.1038/ncb3171

By:

Cianfanelli, Valentina;
Fuoco, Claudia;
Lorente, Mar;
Salazar, Maria;
Quondamatteo, Fabio;
Gherardini, Pier Federico;
De Zio, Daniela;
Nazio, Francesca;
Antonioli, Manuela;
D'Orazio, Melania;
Skobo, Tatjana;
Bordi, Matteo;
Rohde, Mikkel;
Valle, Luisa Dalla;
Helmer-Citterich, Manuela;
Gretzmeier, Christine;
Dengjel, Joern;
Fimia, Gian Maria;
Piacentini, Mauro;
Di Bartolomeo, Sabrina

Publication type:

Article

AMBRA1 links autophagy to cell proliferation and tumorigenesis by promoting c-Myc dephosphorylation and degradation.

Published in:

Nature Cell Biology, 2015, v. 17, n. 1, p. 20, doi. 10.1038/ncb3072

By:

Cianfanelli, Valentina;
Fuoco, Claudia;
Lorente, Mar;
Salazar, Maria;
Quondamatteo, Fabio;
Gherardini, Pier Federico;
De Zio, Daniela;
Nazio, Francesca;
Antonioli, Manuela;
D'Orazio, Melania;
Skobo, Tatjana;
Bordi, Matteo;
Rohde, Mikkel;
Dalla Valle, Luisa;
Helmer-Citterich, Manuela;
Gretzmeier, Christine;
Dengjel, Joern;
Fimia, Gian Maria;
Piacentini, Mauro;
Di Bartolomeo, Sabrina

Publication type:

Article

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.

Published in:

Nature Cell Biology, 2013, v. 15, n. 4, p. 406, doi. 10.1038/ncb2708

By:

Nazio, Francesca;
Strappazzon, Flavie;
Antonioli, Manuela;
Bielli, Pamela;
Cianfanelli, Valentina;
Bordi, Matteo;
Gretzmeier, Christine;
Dengjel, Joern;
Piacentini, Mauro;
Fimia, Gian Maria;
Cecconi, Francesco

Publication type:

Article

MYC up-regulation confers vulnerability to dual inhibition of CDK12 and CDK13 in high-risk Group 3 medulloblastoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2023, v. 42, n. 1, p. 1, doi. 10.1186/s13046-023-02790-2

By:

Pitolli, Consuelo;
Marini, Alberto;
Guerra, Marika;
Pieraccioli, Marco;
Marabitti, Veronica;
Palluzzi, Fernando;
Giacò, Luciano;
Tamburrini, Gianpiero;
Cecconi, Francesco;
Nazio, Francesca;
Sette, Claudio;
Pagliarini, Vittoria

Publication type:

Article

MYC up-regulation confers vulnerability to dual inhibition of CDK12 and CDK13 in high-risk Group 3 medulloblastoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2023, v. 42, n. 1, p. 1, doi. 10.1186/s13046-023-02790-2

By:

Pitolli, Consuelo;
Marini, Alberto;
Guerra, Marika;
Pieraccioli, Marco;
Marabitti, Veronica;
Palluzzi, Fernando;
Giacò, Luciano;
Tamburrini, Gianpiero;
Cecconi, Francesco;
Nazio, Francesca;
Sette, Claudio;
Pagliarini, Vittoria

Publication type:

Article

Macroautophagy inhibition maintains fragmented mitochondria to foster T cell receptor-dependent apoptosis.

Published in:

EMBO Journal, 2016, v. 35, n. 16, p. 1793, doi. 10.15252/embj.201593727

By:

Corrado, Mauro;
Mariotti, Francesca R;
Trapani, Laura;
Taraborrelli, Lucia;
Nazio, Francesca;
Cianfanelli, Valentina;
Soriano, Maria Eugenia;
Schrepfer, Emilie;
Cecconi, Francesco;
Scorrano, Luca;
Campello, Silvia

Publication type:

Article

Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy.

Published in:

EMBO Journal, 2011, v. 30, n. 7, p. 1195, doi. 10.1038/emboj.2011.49

By:

Strappazzon, Flavie;
Vietri-Rudan, Matteo;
Campello, Silvia;
Nazio, Francesca;
Florenzano, Fulvio;
Fimia, Gian Maria;
Piacentini, Mauro;
Levine, Beth;
Cecconi, Francesco

Publication type:

Article