Works by Navratilova, Edita

Results: 45

Evaluation of reward from pain relief.

Published in:

Annals of the New York Academy of Sciences, 2013, v. 1282, n. 1, p. 1, doi. 10.1111/nyas.12095

By:

Navratilova, Edita;
Xie, Jennifer Yanhua;
King, Tamara;
Porreca, Frank

Publication type:

Article

Shared Mechanisms of Chronic Pain and Emotional-Motivational Problems: From Basic Science to the Clinics.

Published in:

2018

By:

Becker, Susanne;
Navratilova, Edita;
Nees, Frauke;
Van Damme, Stefaan

Publication type:

Editorial

Emotional and Motivational Pain Processing: Current State of Knowledge and Perspectives in Translational Research.

Published in:

2018

By:

Becker, Susanne;
Navratilova, Edita;
Nees, Frauke;
Van Damme, Stefaan

Publication type:

journal article

Endogenous Opioid Activity in the Anterior Cingulate Cortex Is Required for Relief of Pain.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 18, p. 7264, doi. 10.1523/JNEUROSCI.3862-14.2015

By:

Navratilova, Edita;
Xie, Jennifer Yanhua;
Meske, Diana;
Qu, Chaoling;
Morimura, Kozo;
Okun, Alec;
Arakawa, Naohisa;
Ossipov, Michael;
Fields, Howard L.;
Porreca, Frank

Publication type:

Article

Chemogenetic Manipulation of Amygdala Kappa Opioid Receptor Neurons Modulates Amygdala Neuronal Activity and Neuropathic Pain Behaviors.

Published in:

Cells (2073-4409), 2024, v. 13, n. 8, p. 705, doi. 10.3390/cells13080705

By:

Ji, Guangchen;
Presto, Peyton;
Kiritoshi, Takaki;
Chen, Yong;
Navratilova, Edita;
Porreca, Frank;
Neugebauer, Volker

Publication type:

Article

Relief of neuropathic pain by cell-specific manipulation of nucleus accumbens dopamine D1- and D2-receptor-expressing neurons.

Published in:

Molecular Brain, 2022, v. 15, n. 1, p. 1, doi. 10.1186/s13041-021-00896-2

By:

Sato, Daisuke;
Narita, Michiko;
Hamada, Yusuke;
Mori, Tomohisa;
Tanaka, Kenichi;
Tamura, Hideki;
Yamanaka, Akihiro;
Matsui, Ryosuke;
Watanabe, Dai;
Suda, Yukari;
Senba, Emiko;
Watanabe, Moe;
Navratilova, Edita;
Porreca, Frank;
Kuzumaki, Naoko;
Narita, Minoru

Publication type:

Article

Time-Dependent Changes in Protein Composition of Medial Prefrontal Cortex in Rats with Neuropathic Pain.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 2, p. 955, doi. 10.3390/ijms23020955

By:

Ujcikova, Hana;
Robles, Dagoberto;
Yue, Xu;
Svoboda, Petr;
Lee, Yeon Sun;
Navratilova, Edita

Publication type:

Article

Kappa Opioid Receptor Blockade in the Amygdala Mitigates Pain Like-Behaviors by Inhibiting Corticotropin Releasing Factor Neurons in a Rat Model of Functional Pain.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.903978

By:

Yakhnitsa, Vadim;
Ji, Guangchen;
Hein, Matthew;
Presto, Peyton;
Griffin, Zack;
Ponomareva, Olga;
Navratilova, Edita;
Porreca, Frank;
Neugebauer, Volker

Publication type:

Article

Reward and motivation in pain and pain relief.

Published in:

Nature Neuroscience, 2014, v. 17, n. 10, p. 1304, doi. 10.1038/nn.3811

By:

Navratilova, Edita;
Porreca, Frank

Publication type:

Article

Positive emotions and brain reward circuits in chronic pain.

Published in:

Journal of Comparative Neurology, 2016, v. 524, n. 8, p. 1646, doi. 10.1002/cne.23968

By:

Navratilova, Edita;
Morimura, Kozo;
Xie, Jennifer Y.;
Atcherley, Christopher W.;
Ossipov, Michael H.;
Porreca, Frank

Publication type:

Article

Extracellular N-acetylaspartylglutamate released in the nucleus accumbens modulates the pain sensation: Analysis using a microdialysis/mass spectrometry integrated system.

Published in:

Molecular Pain, 2018, v. 14, p. 1, doi. 10.1177/1744806918754934

By:

Moe Watanabe;
Yuki Sugiura;
Eiji Sugiyama;
Michiko Narita;
Navratilova, Edita;
Takashige Kondo;
Naohiko Uchiyama;
Akihiro Yamanaka;
Naoko Kuzumaki;
Porreca, Frank;
Minoru Narita

Publication type:

Article

Activation of ventral tegmental area dopaminergic neurons reverses pathological allodynia resulting from nerve injury or bone cancer.

Published in:

Molecular Pain, 2018, v. 14, p. 1, doi. 10.1177/1744806918756406

By:

Moe Watanabe;
Michiko Narita;
Yusuke Hamada;
Akira Yamashita;
Hideki Tamura;
Daigo Ikegami;
Takashige Kondo;
Tatsuto Shinzato;
Takatsune Shimizu;
Yumi Fukuchi;
Akihiro Muto;
Hideyuki Okano;
Akihiro Yamanaka;
Vivianne L. Tawfik;
Naoko Kuzumaki;
Edita Navratilova;
Frank Porreca;
Minoru Narita

Publication type:

Article

Parallel synthesis and biological evaluation of different sizes of bicyclo<sup>[2,3]</sup>-Leu-enkephalin analogues.

Published in:

Biopolymers, 2005, v. 80, n. 2/3, p. 151, doi. 10.1002/bip.20208

By:

Gu, Xuyuan;
Ying, Jinfa;
Min, Byoung;
Cain, James P.;
Davis, Peg;
Willey, Patrick;
Navratilova, Edita;
Yamamura, Henry I.;
Porreca, Frank;
Hruby, Victor J.

Publication type:

Article

Preclinical Assessment of the Analgesic Pharmacology of NKTR-181 in Rodents.

Published in:

Cellular & Molecular Neurobiology, 2021, v. 41, n. 5, p. 949, doi. 10.1007/s10571-020-00816-3

By:

Kopruszinski, Caroline M.;
Swiokla, Juliana;
Lee, Yeon Sun;
Navratilova, Edita;
VanderVeen, Laurie;
Yang, Miao;
Liu, Yi;
Miyazaki, Takahiro;
Schmidt, William K.;
Zalevsky, Jonathan;
Porreca, Frank

Publication type:

Article

Efficacy of MEDI0618, a pH-dependent monoclonal antibody targeting PAR2, in preclinical models of migraine.

Published in:

Brain: A Journal of Neurology, 2025, v. 148, n. 4, p. 1345, doi. 10.1093/brain/awae344

By:

Kopruszinski, Caroline M;
Linley, John E;
Thornton, Peter;
Walker, Alison S;
Newton, Philip;
Podichetty, Sadhana;
Ruparel, Radhey Hemendra;
Souza, Luiz Henrique Moreira de;
Navratilova, Edita;
Meno-Tetang, Guy;
Gurrell, Ian;
Dodick, David W;
Dobson, Claire;
Chessell, Tharani;
Porreca, Frank;
Chessell, Iain

Publication type:

Article

Nociceptors are functionally male or female: from mouse to monkey to man.

Published in:

Brain: A Journal of Neurology, 2024, v. 147, n. 12, p. 4280, doi. 10.1093/brain/awae179

By:

Stratton, Harrison;
Lee, Grace;
Dolatyari, Mahdi;
Ghetti, Andre;
Cotta, Tamara;
Mitchell, Stefanie;
Yue, Xu;
Ibrahim, Mohab;
Dumaire, Nicolas;
Salih, Lyuba;
Moutal, Aubin;
François-Moutal, Liberty;
Martin, Laurent;
Navratilova, Edita;
Porreca, Frank

Publication type:

Article

Chronic pain recruits hypothalamic dynorphin/kappa opioid receptor signalling to promote wakefulness and vigilance.

Published in:

Brain: A Journal of Neurology, 2023, v. 146, n. 3, p. 1186, doi. 10.1093/brain/awac153

By:

Ito, Hisakatsu;
Navratilova, Edita;
Vagnerova, Barbora;
Watanabe, Moe;
Kopruszinski, Carol;
Souza, Luiz H Moreira de;
Yue, Xu;
Ikegami, Daigo;
Moutal, Aubin;
Patwardhan, Amol;
Khanna, Rajesh;
Yamazaki, Mitsuaki;
Guerrero, Miguel;
Rosen, Hugh;
Roberts, Ed;
Neugebauer, Volker;
Dodick, David W;
Porreca, Frank

Publication type:

Article

Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine.

Published in:

2022

By:

Watanabe, Moe;
Kopruszinski, Caroline M;
Moutal, Aubin;
Ikegami, Daigo;
Khanna, Rajesh;
Chen, Yanxia;
Ross, Sarah;
Mackenzie, Kimberly;
Stratton, Jennifer;
Dodick, David W;
Navratilova, Edita;
Porreca, Frank

Publication type:

journal article

Female-selective mechanisms promoting migraine.

Published in:

Journal of Headache & Pain, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s10194-024-01771-w

By:

Singh, Shagun;
Kopruszinski, Caroline M.;
Watanabe, Moe;
Dodick, David W.;
Navratilova, Edita;
Porreca, Frank

Publication type:

Article

Exploring the neurobiology of the premonitory phase of migraine preclinically – a role for hypothalamic kappa opioid receptors?

Published in:

Journal of Headache & Pain, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s10194-022-01497-7

By:

Kopruszinski, Caroline M.;
Vizin, Robson;
Watanabe, Moe;
Martinez, Ashley L.;
de Souza, Luiz Henrique Moreira;
Dodick, David W.;
Porreca, Frank;
Navratilova, Edita

Publication type:

Article

Unraveling the directional relationship of sleep and migraine-like pain.

Published in:

Brain Communications, 2024, v. 6, n. 2, p. 1, doi. 10.1093/braincomms/fcae051

By:

Vizin, Robson C Lillo;
Kopruszinski, Caroline M;
Redman, Paula M;
Ito, Hisakatsu;
Rau, Jill;
Dodick, David W;
Navratilova, Edita;
Porreca, Frank

Publication type:

Article

Sexual dimorphism in functional pain syndromes.

Published in:

Science Translational Medicine, 2021, v. 13, n. 619, p. 1, doi. 10.1126/scitranslmed.abj7180

By:

Navratilova, Edita;
Fillingim, Roger B.;
Porreca, Frank

Publication type:

Article

The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females.

Published in:

Science Translational Medicine, 2020, v. 12, n. 529, p. 1, doi. 10.1126/scitranslmed.aay7550

By:

Chen, Yanxia;
Moutal, Aubin;
Navratilova, Edita;
Kopruszinski, Caroline;
Yue, Xu;
Ikegami, Megumi;
Chow, Michele;
Kanazawa, Iori;
Bellampalli, Shreya Sai;
Xie, Jennifer;
Patwardhan, Amol;
Rice, Kenner;
Fields, Howard;
Akopian, Armen;
Neugebauer, Volker;
Dodick, David;
Khanna, Rajesh;
Porreca, Frank

Publication type:

Article

Cortical kappa opioid receptors integrate negative affect and sleep disturbance.

Published in:

Translational Psychiatry, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41398-024-03123-3

By:

Lillo Vizin, Robson C.;
Ito, Hisakatsu;
Kopruszinski, Caroline M.;
Ikegami, Megumi;
Ikegami, Daigo;
Yue, Xu;
Navratilova, Edita;
Moutal, Aubin;
Cowen, Stephen L.;
Porreca, Frank

Publication type:

Article

Longitudinal analysis of pain-induced brain activations in post-traumatic headache.

Published in:

Cephalalgia, 2025, v. 45, n. 5, p. 1, doi. 10.1177/03331024251345160

By:

Ku, Dohyun;
Mao, Lingchao;
Nikolova, Simona;
Dumkrieger, Gina M.;
Ross, Katherine B.;
Huentelman, Matthew;
Anderson, Trent;
Porreca, Frank;
Navratilova, Edita;
Starling, Amaal;
Wu, Teresa;
Li, Jing;
Chong, Catherine D.;
Schwedt, Todd J.

Publication type:

Article

Advancing understanding of migraine pathophysiology and therapy by consideration of patient sex.

Published in:

Cephalalgia, 2025, v. 45, n. 5, p. 1, doi. 10.1177/03331024251339466

By:

Porreca, Frank;
Navratilova, Edita;
Dodick, David W

Publication type:

Article

Sex differences in effectiveness of CGRP receptor antagonism for treatment of acute and persistent headache-like pain in a mouse model of mild traumatic brain injury.

Published in:

Cephalalgia, 2025, v. 45, n. 2, p. 1, doi. 10.1177/03331024251321087

By:

Navratilova, Edita;
Kopruszinski, Caroline M.;
Oyarzo, Janice;
Barber, Kara R.;
Anderson, Trent;
Dodick, David W.;
Schwedt, Todd J.;
Porreca, Frank

Publication type:

Article

Chronification of migraine sensitizes to CGRP in male and female mice.

Published in:

Cephalalgia, 2025, v. 45, n. 2, p. 1, doi. 10.1177/03331024251317446

By:

Guzman, Gege;
Kopruszinski, Caroline M.;
Barber, Kara R.;
Lillo Vizin, Robson C.;
Dodick, David W.;
Navratilova, Edita;
Porreca, Frank

Publication type:

Article

Prolactin-induced sensitization of trigeminal nociceptors promotes migraine co-morbidity in endometriosis.

Published in:

Cephalalgia, 2025, v. 45, n. 1, p. 1, doi. 10.1177/03331024241313378

By:

Lee, Grace J.;
Hode, Veronica;
Georgieva, Teodora;
Rau, Jill;
Dodick, David W.;
Schwedt, Todd J.;
Neugebauer, Volker;
Porreca, Frank;
Navratilova, Edita

Publication type:

Article

A male-specific mechanism of meningeal nociceptor sensitization promoting migraine headache.

Published in:

Cephalalgia, 2024, v. 44, n. 9, p. 1, doi. 10.1177/03331024241281493

By:

Kopruszinski, Caroline M.;
Lee, Grace;
Martin, Laurent K.;
Barber, Kara R.;
Moutal, Aubin;
Dodick, David W.;
Navratilova, Edita;
Porreca, Frank

Publication type:

Article

Evaluation of outcomes of calcitonin gene-related peptide (CGRP)-targeting therapies for acute and preventive migraine treatment based on patient sex.

Published in:

Cephalalgia, 2024, v. 44, n. 3, p. 1, doi. 10.1177/03331024241238153

By:

Porreca, Frank;
Navratilova, Edita;
Hirman, Joe;
van den Brink, Antoinette Maassen;
Lipton, Richard B;
Dodick, David W

Publication type:

Article

Identification of brain areas in mice with peak neural activity across the acute and persistent phases of post-traumatic headache.

Published in:

Cephalalgia, 2023, v. 43, n. 11, p. 1, doi. 10.1177/03331024231217469

By:

Rudolph, Megan;
Kopruszinski, Caroline;
Wu, Chen;
Navratilova, Edita;
Schwedt, Todd J.;
Dodick, David W.;
Porreca, Frank;
Anderson, Trent

Publication type:

Article

Preclinical assessment of onabotulinumtoxinA for the treatment of mild traumatic brain injury-related acute and persistent post-traumatic headache.

Published in:

Cephalalgia, 2022, v. 42, n. 11/12, p. 1194, doi. 10.1177/03331024221099841

By:

Navratilova, Edita;
Oyarzo, Janice;
Anderson, Trent;
Broide, Ron S;
Subramaniam, Sudhakar R;
Vazquez-Cintron, Edwin J;
Brin, Mitchell F;
Schwedt, Todd J;
Dodick, David W;
Porreca, Frank

Publication type:

Article

A prolactin-dependent sexually dimorphic mechanism of migraine chronification.

Published in:

Cephalalgia, 2022, v. 42, n. 3, p. 197, doi. 10.1177/03331024211039813

By:

Ikegami, Daigo;
Navratilova, Edita;
Yue, Xu;
Moutal, Aubin;
Kopruszinski, Caroline M;
Khanna, Rajesh;
Patwardhan, Amol;
Dodick, David W;
Porreca, Frank

Publication type:

Article

CGRP monoclonal antibody prevents the loss of diffuse noxious inhibitory controls (DNIC) in a mouse model of post-traumatic headache.

Published in:

Cephalalgia, 2021, v. 41, n. 6, p. 749, doi. 10.1177/0333102420981688

By:

Kopruszinski, Caroline M;
Turnes, Joelle M;
Swiokla, Juliana;
Weinstein, Troy J;
Schwedt, Todd J;
Dodick, David W;
Anderson, Trent;
Navratilova, Edita;
Porreca, Frank

Publication type:

Article

A novel, injury-free rodent model of vulnerability for assessment of acute and preventive therapies reveals temporal contributions of CGRP-receptor activation in migraine-like pain.

Published in:

Cephalalgia, 2021, v. 41, n. 3, p. 305, doi. 10.1177/0333102420959794

By:

Kopruszinski, Caroline M;
Navratilova, Edita;
Swiokla, Juliana;
Dodick, David W;
Chessell, Iain P;
Porreca, Frank

Publication type:

Article

Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine.

Published in:

Cephalalgia, 2020, v. 40, n. 14, p. 1535, doi. 10.1177/0333102420966581

By:

Kopruszinski, Caroline M;
Thornton, Peter;
Arnold, Joanne;
Newton, Philip;
Lowne, David;
Navratilova, Edita;
Swiokla, Juliana;
Dodick, David W;
Dobson, Claire;
Gurrell, Ian;
Chessell, Iain Patrick;
Porreca, Frank

Publication type:

Article

Ubrogepant does not induce latent sensitization in a preclinical model of medication overuse headache.

Published in:

2020

By:

Navratilova, Edita;
Behravesh, Sasan;
Oyarzo, Janice;
Dodick, David W;
Banerjee, Pradeep;
Porreca, Frank

Publication type:

journal article

Evaluation of LY573144 (lasmiditan) in a preclinical model of medication overuse headache.

Published in:

2020

By:

Rau, Jill C;
Navratilova, Edita;
Oyarzo, Janice;
Johnson, Kirk W;
Aurora, Sheena K;
Schwedt, Todd J;
Dodick, David W;
Porreca, Frank

Publication type:

journal article

Cannabinoids induce latent sensitization in a preclinical model of medication overuse headache.

Published in:

2020

By:

Kopruszinski, Caroline M;
Navratilova, Edita;
Vagnerova, Barbora;
Swiokla, Juliana;
Patwardhan, Amol;
Dodick, David;
Porreca, Frank

Publication type:

journal article

CGRP-dependent and independent mechanisms of acute and persistent post-traumatic headache following mild traumatic brain injury in mice.

Published in:

2019

By:

Navratilova, Edita;
Rau, Jill;
Oyarzo, Janice;
Tien, Jason;
Mackenzie, Kimberly;
Stratton, Jennifer;
Remeniuk, Bethany;
Schwedt, Todd;
Anderson, Trent;
Dodick, David;
Porreca, Frank

Publication type:

journal article

Sustained exposure to acute migraine medications combined with repeated noxious stimulation dysregulates descending pain modulatory circuits: Relevance to medication overuse headache.

Published in:

2019

By:

Nation, Kelsey M;
Dodick, David W;
Navratilova, Edita;
Porreca, Frank

Publication type:

journal article

Anatomy and immunochemical characterization of the non-arterial peptidergic diffuse dural innervation of the rat and Rhesus monkey: Implications for functional regulation and treatment in migraine.

Published in:

2017

By:

Rice, Frank L.;
Xie, Jennifer Y.;
Albrecht, Phillip J.;
Acker, Emily;
Bourgeois, Justin;
Navratilova, Edita;
Dodick, David W.;
Porreca, Frank

Publication type:

journal article

Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention.

Published in:

2017

By:

Xie, Jennifer Y.;
De Felice, Milena;
Kopruszinski, Caroline M.;
Eyde, Nathan;
Lavigne, Justin;
Remeniuk, Bethany;
Hernandez, Pablo;
Xu Yue;
Naomi Goshima;
Ossipov, Michael;
King, Tamara;
Streicher, John M.;
Navratilova, Edita;
Dodick, David;
Rosen, Hugh;
Roberts, Ed;
Porreca, Frank;
Yue, Xu;
Goshima, Naomi

Publication type:

journal article

Discovery and characterization of prolactin neutralizing monoclonal antibodies for the treatment of female-prevalent pain disorders.

Published in:

2023

By:

Maciuba, Stephanie;
Bowden, Gregory D.;
Stratton, Harrison J.;
Wisniewski, Kazimierz;
Schteingart, Claudio D.;
Almagro, Juan C.;
Valadon, Philippe;
Lowitz, Joshua;
Glaser, Scott M.;
Lee, Grace;
Dolatyari, Mahdi;
Navratilova, Edita;
Porreca, Frank;
Rivière, Pierre J.M.

Publication type:

Report