Works by Narendra, Derek P

Results: 22

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin.

Published in:

PLoS Biology, 2010, v. 8, n. 1, p. 1, doi. 10.1371/journal.pbio.1000298

By:

Narendra, Derek P.;
Seok Min Jin;
Tanaka, Atsushi;
Der-Fen Suen;
Gautier, Clement A.;
Jie Shen;
Cookson, Mark R.;
Youle, Richard J.

Publication type:

Article

A Woman in Her 40s With Headache and New-Onset Seizures.

Published in:

JAMA Neurology, 2017, v. 74, n. 4, p. 476, doi. 10.1001/jamaneurol.2016.2961

By:

Graham, Maya S.;
Pudusseri, Anita;
Helgager, Jeffrey;
Narendra, Derek P.;
De Girolami, Umberto;
Pinkus, Geraldine S.;
Sanchorawala, Vaishali;
Miyawaki, Edison

Publication type:

Article

DELE1 maintains muscle proteostasis to promote growth and survival in mitochondrial myopathy.

Published in:

EMBO Journal, 2024, v. 43, n. 22, p. 5548, doi. 10.1038/s44318-024-00242-x

By:

Lin, Hsin-Pin;
Petersen, Jennifer D;
Gilsrud, Alexandra J;
Madruga, Angelo;
D'Silva, Theresa M;
Huang, Xiaoping;
Shammas, Mario K;
Randolph, Nicholas P;
Johnson, Kory R;
Li, Yan;
Jones, Drew R;
Pacold, Michael E;
Narendra, Derek P

Publication type:

Article

Midbrain on Fire: mtDNA Ignites Neuroinflammation in PRKN-P.

Published in:

2022

By:

Narendra, Derek P.;
Thayer, Julia A.

Publication type:

Editorial

α‐Synuclein Deposition in Sympathetic Nerve Fibers in Genetic Forms of Parkinson's Disease.

Published in:

Movement Disorders, 2021, v. 36, n. 10, p. 2346, doi. 10.1002/mds.28667

By:

Isonaka, Risa;
Goldstein, David S.;
Zhu, William;
Yoon, Esther;
Ehrlich, Debra;
Schindler, Alice B.;
Kokkinis, Angela D.;
Sabir, Marya S.;
Scholz, Sonja W.;
Bandres‐Ciga, Sara;
Blauwendraat, Cornelis;
Gonzalez‐Alegre, Pedro;
Lopez, Grisel;
Sidransky, Ellen;
Narendra, Derek P.

Publication type:

Article

Neurodegeneration: Trouble in the cell's powerhouse.

Published in:

Nature, 2012, v. 483, n. 7390, p. 418, doi. 10.1038/nature10952

By:

Narendra, Derek P.;
Youle, Richard J.

Publication type:

Article

Mechanisms of mitophagy.

Published in:

Nature Reviews Molecular Cell Biology, 2011, v. 12, n. 1, p. 9, doi. 10.1038/nrm3028

By:

Youle, Richard J.;
Narendra, Derek P.

Publication type:

Article

CHCHD10 mutations induce tissue-specific mitochondrial DNA deletions with a distinct signature.

Published in:

Human Molecular Genetics, 2024, v. 33, n. 1, p. 91, doi. 10.1093/hmg/ddad161

By:

Shammas, Mario K;
Nie, Yu;
Gilsrud, Alexandra;
Huang, Xiaoping;
Narendra, Derek P;
Chinnery, Patrick F

Publication type:

Article

Loss of CHCHD2 and CHCHD10 activates OMA1 peptidase to disrupt mitochondrial cristae phenocopying patient mutations.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 9, p. 1547, doi. 10.1093/hmg/ddaa077

By:

Liu, Yi-Ting;
Huang, Xiaoping;
Nguyen, Diana;
Shammas, Mario K;
Wu, Beverly P;
Dombi, Eszter;
Springer, Danielle A;
Poulton, Joanna;
Sekine, Shiori;
Narendra, Derek P

Publication type:

Article

CHCHD2 accumulates in distressed mitochondria and facilitates oligomerization of CHCHD10.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 2, p. 349, doi. 10.1093/hmg/ddy340

By:

Huang, Xiaoping;
Wu, Beverly P;
Nguyen, Diana;
Liu, Yi-Ting;
Marani, Melika;
Hench, Jürgen;
Bénit, Paule;
Kozjak-Pavlovic, Vera;
Rustin, Pierre;
Frank, Stephan;
Narendra, Derek P

Publication type:

Article

PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding.

Published in:

Journal of Cell Biology, 2013, v. 200, n. 2, p. 163, doi. 10.1083/jcb.201210111

By:

Lazarou, Michael;
Narendra, Derek P.;
Jin, Seok Min;
Tekle, Ephrem;
Banerjee, Soojay;
Youle, Richard J.

Publication type:

Article

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin.

Published in:

Journal of Cell Biology, 2010, v. 191, n. 7, p. 1367, doi. 10.1083/jcb.201007013

By:

Tanaka, Atsushi;
Cleland, Megan M.;
Shan Xu;
Narendra, Derek P.;
Der-Fen Suen;
Karbowski, Mariusz;
Youle, Richard J.

Publication type:

Article

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL.

Published in:

Journal of Cell Biology, 2010, v. 191, n. 5, p. 933, doi. 10.1083/jcb.201008084

By:

Jin, Seok Min;
Lazarou, Michael;
Wang, Chunxin;
Kane, Lesley A.;
Narendra, Derek P.;
Youle, Richard J.

Publication type:

Article

Coupling APEX labeling to imaging mass spectrometry of single organelles reveals heterogeneity in lysosomal protein turnover.

Published in:

Journal of Cell Biology, 2020, v. 219, n. 1, p. 1, doi. 10.1083/jcb.201901097

By:

Narendra, Derek P.;
Guillermier, Christelle;
Gyngard, Frank;
Huang, Xiaoping;
Ward, Michael E.;
Steinhauser, Matthew L.

Publication type:

Article

PINK1 rendered temperature sensitive by disease-associated and engineered mutations.

Published in:

Human Molecular Genetics, 2013, v. 22, n. 13, p. 2572, doi. 10.1093/hmg/ddt106

By:

Narendra, Derek P.;
Wang, Chunxin;
Youle, Richard J.;
Walker, John E.

Publication type:

Article

How to treat a "sweetheart" in mitochondrial cardiomyopathy.

Published in:

EMBO Molecular Medicine, 2024, v. 16, n. 6, p. 1226, doi. 10.1038/s44321-024-00070-w

By:

Lin, Hsin-Pin;
Narendra, Derek P

Publication type:

Article

CHCHD2 and CHCHD10-related neurodegeneration: molecular pathogenesis and the path to precision therapy.

Published in:

Biochemical Society Transactions, 2023, v. 51, n. 2, p. 797, doi. 10.1042/BST20221365

By:

Shammas, Mario K.;
Tzu-Hsiang Huang;
Narendra, Derek P.

Publication type:

Article

Structural and Functional Characterization of the Most Frequent Pathogenic PRKN Substitution p.R275W.

Published in:

Cells (2073-4409), 2024, v. 13, n. 18, p. 1540, doi. 10.3390/cells13181540

By:

Bustillos, Bernardo A.;
Cocker, Liam T.;
Coban, Mathew A.;
Weber, Caleb A.;
Bredenberg, Jenny M.;
Boneski, Paige K.;
Siuda, Joanna;
Slawek, Jaroslaw;
Puschmann, Andreas;
Narendra, Derek P.;
Graff-Radford, Neill R.;
Wszolek, Zbigniew K.;
Dickson, Dennis W.;
Ross, Owen A.;
Caulfield, Thomas R.;
Springer, Wolfdieter;
Fiesel, Fabienne C.

Publication type:

Article

Comment on "mt-Keima detects PINK1-PRKN mitophagy in vivo with greater sensitivity than mito-QC".

Published in:

Autophagy, 2021, v. 17, n. 12, p. 4484, doi. 10.1080/15548627.2021.1909999

By:

Liu, Yi-Ting;
Sliter, Danielle A.;
Shammas, Mario K;
Huang, Xiaoping;
Wang, Chunxin;
Calvelli, Hannah;
Maric, Dragan S.;
Narendra, Derek P.

Publication type:

Article

Mt-Keima detects PINK1-PRKN mitophagy in vivo with greater sensitivity than mito-QC.

Published in:

Autophagy, 2021, v. 17, n. 11, p. 3753, doi. 10.1080/15548627.2021.1896924

By:

Liu, Yi-Ting;
Sliter, Danielle A.;
Shammas, Mario K.;
Huang, Xiaoping;
Wang, Chunxin;
Calvelli, Hannah;
Maric, Dragan S.;
Narendra, Derek P.

Publication type:

Article

Heterozygous PRKN mutations are common but do not increase the risk of Parkinson's disease.

Published in:

2022

By:

Zhu, William;
Huang, Xiaoping;
Yoon, Esther;
Bandres-Ciga, Sara;
Blauwendraat, Cornelis;
Billingsley, Kimberly J;
Cade, Joshua H;
Wu, Beverly P;
Williams, Victoria H;
Schindler, Alice B;
Brooks, Janet;
Gibbs, J Raphael;
Hernandez, Dena G;
Ehrlich, Debra;
Singleton, Andrew B;
Narendra, Derek P

Publication type:

journal article

Sorting out Parkinson's disease: one cell at a time.

Published in:

2022

By:

Lin, Hsin-Pin;
Narendra, Derek P.

Publication type:

Editorial