Works by Naldini, Luigi

Results: 133

Deletion in a (T)8 microsatellite abrogates expression regulation by 3′‐UTR.

Published in:

Nucleic Acids Research, 2003, v. 31, n. 22, p. 6561, doi. 10.1093/nar/gkg858

By:

Ruggiero, Tina;
Olivero, Martina;
Follenzi, Antonia;
Naldini, Luigi;
Calogero, Raffaele;
Di Renzo, Maria Flavia

Publication type:

Article

Development and maturation of invariant NKT cells in the presence of lysosomal engulfment.

Published in:

European Journal of Immunology, 2009, v. 39, n. 10, p. 2748, doi. 10.1002/eji.200939639

By:

Plati, Tiziana;
Visigalli, Ilaria;
Capotondo, Alessia;
Buono, Mario;
Naldini, Luigi;
Cosma, Maria Pia;
Biffi, Alessandra

Publication type:

Article

A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors.

Published in:

Cancers, 2021, v. 13, n. 2, p. 230, doi. 10.3390/cancers13020230

By:

Costa, Barbara;
Fletcher, Michael N. C.;
Boskovic, Pavle;
Ivanova, Ekaterina L.;
Eisemann, Tanja;
Lohr, Sabrina;
Bunse, Lukas;
Löwer, Martin;
Burchard, Stefanie;
Korshunov, Andrey;
Coltella, Nadia;
Cusimano, Melania;
Naldini, Luigi;
Liu, Hai-Kun;
Platten, Michael;
Radlwimmer, Bernhard;
Angel, Peter;
Peterziel, Heike

Publication type:

Article

BAR-Seq clonal tracking of gene-edited cells.

Published in:

Nature Protocols, 2021, v. 16, n. 6, p. 2991, doi. 10.1038/s41596-021-00529-x

By:

Ferrari, Samuele;
Beretta, Stefano;
Jacob, Aurelien;
Cittaro, Davide;
Albano, Luisa;
Merelli, Ivan;
Naldini, Luigi;
Genovese, Pietro

Publication type:

Article

Lentiviral vectors: excellent tools for experimental gene transfer and promising candidates for gene therapy.

Published in:

Journal of Gene Medicine, 2000, v. 2, n. 5, p. 308, doi. 10.1002/1521-2254(200009/10)2:5<308::AID-JGM131>3.0.CO;2-3

By:

Vigna, Elisa;
Naldini, Luigi

Publication type:

Article

Interferon gene therapy reprograms the leukemia microenvironment inducing protective immunity to multiple tumor antigens.

Published in:

Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-05315-0

By:

Escobar, Giulia;
Barbarossa, Luigi;
Barbiera, Giulia;
Norelli, Margherita;
Genua, Marco;
Ranghetti, Anna;
Plati, Tiziana;
Camisa, Barbara;
Brombin, Chiara;
Cittaro, Davide;
Annoni, Andrea;
Bondanza, Attilio;
Ostuni, Renato;
Gentner, Bernhard;
Naldini, Luigi

Publication type:

Article

Lentiviral gene transfer ameliorates disease progression in Long-Evans cinnamon rats: An animal model for Wilson disease.

Published in:

Scandinavian Journal of Gastroenterology, 2006, v. 41, n. 8, p. 974, doi. 10.1080/00365520600554790

By:

Merle, Uta;
Enckea, Jens;
Tuma, Sabine;
Volkmann, Martin;
Naldini, Luigi;
Stremmel, Wolfgang

Publication type:

Article

Genetic engineering of hematopoiesis: current stage of clinical translation and future perspectives.

Published in:

EMBO Molecular Medicine, 2019, v. 11, n. 3, p. N.PAG, doi. 10.15252/emmm.201809958

By:

Naldini, Luigi

Publication type:

Article

Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next‐generation human artificial chromosomes for Duchenne muscular dystrophy.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 2, p. 254, doi. 10.15252/emmm.201607284

By:

Benedetti, Sara;
Uno, Narumi;
Hoshiya, Hidetoshi;
Ragazzi, Martina;
Ferrari, Giulia;
Kazuki, Yasuhiro;
Moyle, Louise Anne;
Tonlorenzi, Rossana;
Lombardo, Angelo;
Chaouch, Soraya;
Mouly, Vincent;
Moore, Marc;
Popplewell, Linda;
Kazuki, Kanako;
Katoh, Motonobu;
Naldini, Luigi;
Dickson, George;
Messina, Graziella;
Oshimura, Mitsuo;
Cossu, Giulio

Publication type:

Article

Therapeutic gene editing in CD34+ hematopoietic progenitors from Fanconi anemia patients.

Published in:

EMBO Molecular Medicine, 2017, v. 9, n. 11, p. 1574, doi. 10.15252/emmm.201707540

By:

Diez, Begoña;
Genovese, Pietro;
Roman‐Rodriguez, Francisco J;
Alvarez, Lara;
Schiroli, Giulia;
Ugalde, Laura;
Rodriguez‐Perales, Sandra;
Sevilla, Julian;
Diaz de Heredia, Cristina;
Holmes, Michael C;
Lombardo, Angelo;
Naldini, Luigi;
Bueren, Juan Antonio;
Rio, Paula

Publication type:

Article

Genome editing for scalable production of alloantigen-free lentiviral vectors for in vivo gene therapy.

Published in:

EMBO Molecular Medicine, 2017, v. 9, n. 11, p. 1558, doi. 10.15252/emmm.201708148

By:

Milani, Michela;
Annoni, Andrea;
Bartolaccini, Sara;
Biffi, Mauro;
Russo, Fabio;
Di Tomaso, Tiziano;
Raimondi, Andrea;
Lengler, Johannes;
Holmes, Michael C;
Scheiflinger, Friedrich;
Lombardo, Angelo;
Cantore, Alessio;
Naldini, Luigi

Publication type:

Article

Lentiviral vectors escape innate sensing but trigger p53 in human hematopoietic stem and progenitor cells.

Published in:

EMBO Molecular Medicine, 2017, v. 9, n. 9, p. 1198, doi. 10.15252/emmm.201707922

By:

Piras, Francesco;
Riba, Michela;
Petrillo, Carolina;
Lazarevic, Dejan;
Cuccovillo, Ivan;
Bartolaccini, Sara;
Stupka, Elia;
Gentner, Bernhard;
Cittaro, Davide;
Naldini, Luigi;
Kajaste‐Rudnitski, Anna

Publication type:

Article

Gene therapy for ADA-SCID, the first marketing approval of an ex vivo gene therapy in Europe: paving the road for the next generation of advanced therapy medicinal products.

Published in:

EMBO Molecular Medicine, 2017, v. 9, n. 6, p. 737, doi. 10.15252/emmm.201707573

By:

Aiuti, Alessandro;
Roncarolo, Maria Grazia;
Naldini, Luigi

Publication type:

Article

Pervasive supply of therapeutic lysosomal enzymes in the CNS of normal and Krabbe-affected non-human primates by intracerebral lentiviral gene therapy.

Published in:

EMBO Molecular Medicine, 2016, v. 8, n. 5, p. 489, doi. 10.15252/emmm.201505850

By:

Meneghini, Vasco;
Lattanzi, Annalisa;
Tiradani, Luigi;
Bravo, Gabriele;
Morena, Francesco;
Sanvito, Francesca;
Calabria, Andrea;
Bringas, John;
Fisher‐Perkins, Jeanne M;
Dufour, Jason P;
Baker, Kate C;
Doglioni, Claudio;
Montini, Eugenio;
Bunnell, Bruce A;
Bankiewicz, Krystof;
Martino, Sabata;
Naldini, Luigi;
Gritti, Angela

Publication type:

Article

IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment.

Published in:

EMBO Molecular Medicine, 2016, v. 8, n. 2, p. 155, doi. 10.15252/emmm.201505395

By:

Catarinella, Mario;
Monestiroli, Andrea;
Escobar, Giulia;
Fiocchi, Amleto;
Tran, Ngoc Lan;
Aiolfi, Roberto;
Marra, Paolo;
Esposito, Antonio;
Cipriani, Federica;
Aldrighetti, Luca;
Iannacone, Matteo;
Naldini, Luigi;
Guidotti, Luca G;
Sitia, Giovanni

Publication type:

Article

Targeted gene therapy and cell reprogramming in Fanconi anemia.

Published in:

EMBO Molecular Medicine, 2014, v. 6, n. 6, p. 835, doi. 10.15252/emmm.201303374

By:

Rio, Paula;
Baños, Rocio;
Lombardo, Angelo;
Quintana‐Bustamante, Oscar;
Alvarez, Lara;
Garate, Zita;
Genovese, Pietro;
Almarza, Elena;
Valeri, Antonio;
Díez, Begoña;
Navarro, Susana;
Torres, Yaima;
Trujillo, Juan P;
Murillas, Rodolfo;
Segovia, Jose C;
Samper, Enrique;
Surralles, Jordi;
Gregory, Philip D;
Holmes, Michael C;
Naldini, Luigi

Publication type:

Article

Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice.

Published in:

EMBO Molecular Medicine, 2013, v. 5, n. 11, p. 1684, doi. 10.1002/emmm.201302857

By:

Annoni, Andrea;
Cantore, Alessio;
Della Valle, Patrizia;
Goudy, Kevin;
Akbarpour, Mahzad;
Russo, Fabio;
Bartolaccini, Sara;
D'Angelo, Armando;
Roncarolo, Maria Grazia;
Naldini, Luigi

Publication type:

Article

TIE2-expressing monocytes/macrophages regulate revascularization of the ischemic limb.

Published in:

EMBO Molecular Medicine, 2013, v. 5, n. 6, p. 858, doi. 10.1002/emmm.201302752

By:

Patel, Ashish S.;
Smith, Alberto;
Nucera, Silvia;
Biziato, Daniela;
Saha, Prakash;
Attia, Rizwan Q.;
Humphries, Julia;
Mattock, Katherine;
Grover, Steven P.;
Lyons, Oliver T.;
Guidotti, Luca G.;
Siow, Richard;
Ivetic, Aleksandar;
Egginton, Stuart;
Waltham, Matthew;
Naldini, Luigi;
De Palma, Michele;
Modarai, Bijan

Publication type:

Article

Unbiased assessment of genome integrity and purging of adverse outcomes at the target locus upon editing of CD4+ T‐cells for the treatment of Hyper IgM1.

Published in:

EMBO Journal, 2023, v. 42, n. 23, p. 1, doi. 10.15252/embj.2023114188

By:

Canarutto, Daniele;
Asperti, Claudia;
Vavassori, Valentina;
Porcellini, Simona;
Rovelli, Elisabetta;
Paulis, Marianna;
Ferrari, Samuele;
Varesi, Angelica;
Fiumara, Martina;
Jacob, Aurelien;
Sergi Sergi, Lucia;
Visigalli, Ilaria;
Ferrua, Francesca;
González‐Granado, Luis Ignacio;
Lougaris, Vassilios;
Finocchi, Andrea;
Villa, Anna;
Radrizzani, Marina;
Naldini, Luigi

Publication type:

Article

Identification of Hematopoietic Stem Cell-Specific miRNAs Enables Gene Therapy of Globoid Cell Leukodystrophy.

Published in:

Science Translational Medicine, 2010, v. 2, n. 58, p. 1, doi. 10.1126/scitranslmed.3001522

By:

Gentner, Bernhard;
Visigalli, Ilaria;
Hiramatsu, Hidefumi;
Lechman, Eric;
Ungari, Silvia;
Giustacchini, Alice;
Schira, Giulia;
Amendola, Mario;
Quattrini, Angelo;
Martino, Sabata;
Orlacchio, Aldo;
Dick, John E.;
Biffi, Alessandra;
Naldini, Luigi

Publication type:

Article

Lentiviral Vector Gene Transfer Is Limited by the Proteasome at Postentry Steps in Various Types of Stem Cells.

Published in:

Stem Cells, 2008, v. 26, n. 8, p. 2142, doi. 10.1634/stemcells.2007-0705

By:

de Sio, Francesca Romana Santoni;
Gritti, Angela;
Cascio, Paolo;
Neri, Margherita;
Sampaolesi, Maurilio;
Galli, Cesare;
Luban, Jeremy;
Naldini, Luigi

Publication type:

Article

Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences.

Published in:

Nature Genetics, 2000, v. 25, n. 2, p. 217, doi. 10.1038/76095

By:

Follenzi, Antonia;
Ailles, Laurie E.;
Bakovic, Silvia;
Geuna, Massimo;
Naldini, Luigi

Publication type:

Article

Efficient lentiviral transduction of liver requires cell cycling in vivo.

Published in:

Nature Genetics, 2000, v. 24, n. 1, p. 49, doi. 10.1038/71673

By:

Park, Frank;
Ohashi, Kazuo;
Chiu, Winnie;
Naldini, Luigi;
Kay, Mark A.

Publication type:

Article

RNAi technology and lentiviral delivery as a powerful tool to suppress Tpr-Met-mediated tumorigenesis.

Published in:

Cancer Gene Therapy, 2005, v. 12, n. 5, p. 456, doi. 10.1038/sj.cgt.7700815

By:

Taulli, Riccardo;
Accornero, Paolo;
Follenzi, Antonia;
Mangano, Tony;
Morotti, Alessandro;
Scuoppo, Claudio;
Forni, Paolo E;
Bersani, Francesca;
Crepaldi, Tiziana;
Chiarle, Roberto;
Naldini, Luigi;
Ponzetto, Carola

Publication type:

Article

Development of lentiviral vectors for antiangiogenic gene delivery.

Published in:

Cancer Gene Therapy, 2001, v. 8, n. 11, p. 879, doi. 10.1038/sj.cgt.7700388

By:

Shichinohe, Toshiaki;
Bochner, Bernard H;
Mizutani, Kazuo;
Nishida, Miyako;
Hegerich-Gilliam, Susan;
Naldini, Luigi;
Kasahara, Noriyuki

Publication type:

Article

Genome Editing: A Tool For Research and Therapy: Targeted genome editing hits the clinic.

Published in:

Nature Medicine, 2014, v. 20, n. 10, p. 1101, doi. 10.1038/nm.3721

By:

Lombardo, Angelo;
Naldini, Luigi

Publication type:

Article

Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer.

Published in:

Nature Medicine, 2012, v. 18, n. 5, p. 807, doi. 10.1038/nm.2700

By:

Provasi, Elena;
Genovese, Pietro;
Lombardo, Angelo;
Magnani, Zulma;
Liu, Pei-Qi;
Reik, Andreas;
Chu, Victoria;
Paschon, David E;
Zhang, Lei;
Kuball, Jurgen;
Camisa, Barbara;
Bondanza, Attilio;
Casorati, Giulia;
Ponzoni, Maurilio;
Ciceri, Fabio;
Bordignon, Claudio;
Greenberg, Philip D;
Holmes, Michael C;
Gregory, Philip D;
Naldini, Luigi

Publication type:

Article

Endogenous microRNA regulation suppresses transgene expression in hematopoietic lineages and enables stable gene transfer.

Published in:

Nature Medicine, 2006, v. 12, n. 5, p. 585, doi. 10.1038/nm1398

By:

Brown, Brian D.;
Venneri, Mary Anna;
Zingale, Anna;
Sergi, Lucia Sergi;
Naldini, Luigi

Publication type:

Article

Inserting optimism into gene therapy.

Published in:

Nature Medicine, 2006, v. 12, n. 4, p. 386, doi. 10.1038/nm0406-386

By:

Naldini, Luigi

Publication type:

Article

Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells.

Published in:

Nature Medicine, 2003, v. 9, n. 6, p. 789, doi. 10.1038/nm871

By:

De Palma, Michele;
Venneri, Mary Anna;
Roca, Cristina;
Naldini, Luigi

Publication type:

Article

In vivo gene therapy of metachromatic leukodystrophy by lentiviral vectors: correction of neuropathology and protection against learning impairments in affected mice.

Published in:

Nature Medicine, 2001, v. 7, n. 3, p. 310, doi. 10.1038/85454

By:

Consiglio, Antonella;
Quattrini, Angelo;
Martino, Sabata;
Bensadoun, Jean Charles;
Dolcetta, Diego;
Trojani, Alessandra;
Benaglia, Giuliana;
Marchesini, Sergio;
Cestari, Vincenzo;
Oliverio, Alberto;
Bordignon, Claudio;
Naldini, Luigi

Publication type:

Article

Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics.

Published in:

Nature Medicine, 2001, v. 7, n. 1, p. 33, doi. 10.1038/83324

By:

Kay, Mark A.;
Glorioso, Joseph C;
Naldini, Luigi

Publication type:

Article

Characterization of new arylsulfatase A gene mutations reinforces genotype-phenotype correlation in metachromatic leukodystrophy.

Published in:

Human Mutation, 2009, v. 30, n. 10, p. E936, doi. 10.1002/humu.21093

By:

Cesani, Martina;
Capotondo, Alessia;
Plati, Tiziana;
Sergi, Lucia Sergi;
Fumagalli, Francesca;
Roncarolo, Maria Grazia;
Naldini, Luigi;
Comi, Giancarlo;
Sessa, Maria;
Biffi, Alessandra

Publication type:

Article

Gene therapy returns to centre stage.

Published in:

Nature, 2015, v. 526, n. 7573, p. 351, doi. 10.1038/nature15818

By:

Naldini, Luigi

Publication type:

Article

Targeted genome editing in human repopulating haematopoietic stem cells.

Published in:

Nature, 2014, v. 510, n. 7504, p. 235, doi. 10.1038/nature13420

By:

Genovese, Pietro;
Schiroli, Giulia;
Escobar, Giulia;
Di Tomaso, Tiziano;
Firrito, Claudia;
Calabria, Andrea;
Moi, Davide;
Mazzieri, Roberta;
Bonini, Chiara;
Holmes, Michael C.;
Gregory, Philip D.;
van der Burg, Mirjam;
Gentner, Bernhard;
Montini, Eugenio;
Lombardo, Angelo;
Naldini, Luigi

Publication type:

Article

Constitutive IL-1RA production by modified immune cells protects against IL-1–mediated inflammatory disorders.

Published in:

Science Translational Medicine, 2023, v. 15, n. 698, p. 1, doi. 10.1126/scitranslmed.ade3856

By:

Colantuoni, Mariasilvia;
Jofra Hernandez, Raisa;
Pettinato, Emanuela;
Basso-Ricci, Luca;
Magnani, Laura;
Andolfi, Grazia;
Rigamonti, Chiara;
Finardi, Annamaria;
Romeo, Valentina;
Soldi, Monica;
Sergi Sergi, Lucia;
Rocchi, Martina;
Scala, Serena;
Hoffman, Hal M.;
Gregori, Silvia;
Kajaste-Rudnitski, Anna;
Sanvito, Francesca;
Muzio, Luca;
Naldini, Luigi;
Aiuti, Alessandro

Publication type:

Article

Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models.

Published in:

Science Translational Medicine, 2022, v. 14, n. 653, p. 1, doi. 10.1126/scitranslmed.abl4106

By:

Birocchi, Filippo;
Cusimano, Melania;
Rossari, Federico;
Beretta, Stefano;
Rancoita, Paola M. V.;
Ranghetti, Anna;
Colombo, Stefano;
Costa, Barbara;
Angel, Peter;
Sanvito, Francesca;
Callea, Marcella;
Norata, Rossana;
Chaabane, Linda;
Canu, Tamara;
Spinelli, Antonello;
Genua, Marco;
Ostuni, Renato;
Merelli, Ivan;
Coltella, Nadia;
Naldini, Luigi

Publication type:

Article

Therapeutic liver repopulation by transient acetaminophen selection of gene-modified hepatocytes.

Published in:

Science Translational Medicine, 2021, v. 13, n. 597, p. 1, doi. 10.1126/scitranslmed.abg3047

By:

Vonada, Anne;
Tiyaboonchai, Amita;
Nygaard, Sean;
Posey, Jeffrey;
Peters, Alexander Mack;
Winn, Shelley R.;
Cantore, Alessio;
Naldini, Luigi;
Harding, Cary O.;
Grompe, Markus

Publication type:

Article

Phagocytosis-shielded lentiviral vectors improve liver gene therapy in nonhuman primates.

Published in:

Science Translational Medicine, 2019, v. 11, n. 493, p. N.PAG, doi. 10.1126/scitranslmed.aav7325

By:

Milani, Michela;
Annoni, Andrea;
Moalli, Federica;
Liu, Tongyao;
Cesana, Daniela;
Calabria, Andrea;
Bartolaccini, Sara;
Biffi, Mauro;
Russo, Fabio;
Visigalli, Ilaria;
Raimondi, Andrea;
Patarroyo-White, Susannah;
Drager, Douglas;
Cristofori, Patrizia;
Ayuso, Eduard;
Montini, Eugenio;
Peters, Robert;
Iannacone, Matteo;
Cantore, Alessio;
Naldini, Luigi

Publication type:

Article

Mobilization-based engraftment of haematopoietic stem cells: a new perspective for chemotherapy-free gene therapy and transplantation.

Published in:

British Medical Bulletin, 2023, v. 147, n. 1, p. 108, doi. 10.1093/bmb/ldad017

By:

Canarutto, Daniele;
Javed, Attya Omer;
Pedrazzani, Gabriele;
Ferrari, Samuele;
Naldini, Luigi

Publication type:

Article

Lentiviral vector-based insertional mutagenesis identifies genes associated with liver cancer.

Published in:

Nature Methods, 2013, v. 10, n. 2, p. 155, doi. 10.1038/nmeth.2331

By:

Ranzani, Marco;
Cesana, Daniela;
Bartholomae, Cynthia C;
Sanvito, Francesca;
Pala, Mauro;
Benedicenti, Fabrizio;
Gallina, Pierangela;
Sergi, Lucia Sergi;
Merella, Stefania;
Bulfone, Alessandro;
Doglioni, Claudio;
von Kalle, Christof;
Kim, Yoon Jun;
Schmidt, Manfred;
Tonon, Giovanni;
Naldini, Luigi;
Montini, Eugenio

Publication type:

Article

Site-specific integration and tailoring of cassette design for sustainable gene transfer.

Published in:

Nature Methods, 2011, v. 8, n. 10, p. 861, doi. 10.1038/nmeth.1674

By:

Lombardo, Angelo;
Cesana, Daniela;
Genovese, Pietro;
Di Stefano, Bruno;
Provasi, Elena;
Colombo, Daniele F;
Neri, Margherita;
Magnani, Zulma;
Cantore, Alessio;
Lo Riso, Pietro;
Damo, Martina;
Pello, Oscar M;
Holmes, Michael C;
Gregory, Philip D;
Gritti, Angela;
Broccoli, Vania;
Bonini, Chiara;
Naldini, Luigi

Publication type:

Article

Ex vivo gene transfer and correction for cell-based therapies.

Published in:

2011

By:

Naldini, Luigi

Publication type:

journal article

Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications.

Published in:

2009

By:

Brown, Brian D.;
Naldini, Luigi

Publication type:

journal article

Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1.

Published in:

Science Translational Medicine, 2017, v. 9, n. 411, p. 1, doi. 10.1126/scitranslmed.aan0820

By:

Schiroli, Giulia;
Ferrari, Samuele;
Conway, Anthony;
Jacob, Aurelien;
Capo, Valentina;
Albano, Luisa;
Plati, Tiziana;
Castiello, Maria C.;
Sanvito, Francesca;
Gennery, Andrew R.;
Bovolenta, Chiara;
Palchaudhuri, Rahul;
Scadden, David T.;
Holmes, Michael C.;
Villa, Anna;
Sitia, Giovanni;
Lombardo, Angelo;
Genovese, Pietro;
Naldini, Luigi

Publication type:

Article

Insulin B chain 9–23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs.

Published in:

Science Translational Medicine, 2015, v. 7, n. 289, p. 1, doi. 10.1126/scitranslmed.aaa3032

By:

Akbarpour, Mahzad;
Goudy, Kevin S.;
Cantore, Alessio;
Russo, Fabio;
Sanvito, Francesca;
Naldini, Luigi;
Annoni, Andrea;
Roncarolo, Maria Grazia

Publication type:

Article

Genetic Engineering of Hematopoiesis for Targeted IFN-α Delivery Inhibits Breast Cancer Progression.

Published in:

Science Translational Medicine, 2014, v. 6, n. 217, p. 1, doi. 10.1126/scitranslmed.3006353

By:

Escobar, Giulia;
Moi, Davide;
Ranghetti, Anna;
Ozkal-Baydin, Pinar;
Squadrito, Mario Leonardo;
Kajaste-Rudnitski, Anna;
Bondanza, Attilio;
Gentner, Bernhard;
De Palma, Michele;
Mazzieri, Roberta;
Naldini, Luigi

Publication type:

Article

CD4+ T Cells from IPEX Patients Convert into Functional and Stable Regulatory T Cells by FOXP3 Gene Transfer.

Published in:

Science Translational Medicine, 2013, v. 5, n. 215, p. 1, doi. 10.1126/scitranslmed.3007320

By:

Passerini, Laura;
Mel, Eva Rossi;
Sartirana, Claudia;
Fousteri, Georgia;
Bondanza, Attilio;
Naldini, Luigi;
Roncarolo, Maria Grazia;
Bacchetta, Rosa

Publication type:

Article

Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking.

Published in:

Nature Biotechnology, 2020, v. 38, n. 11, p. 1298, doi. 10.1038/s41587-020-0551-y

By:

Ferrari, Samuele;
Jacob, Aurelien;
Beretta, Stefano;
Unali, Giulia;
Albano, Luisa;
Vavassori, Valentina;
Cittaro, Davide;
Lazarevic, Dejan;
Brombin, Chiara;
Cugnata, Federica;
Kajaste-Rudnitski, Anna;
Merelli, Ivan;
Genovese, Pietro;
Naldini, Luigi

Publication type:

Article

Safer conditioning for blood stem cell transplants.

Published in:

Nature Biotechnology, 2016, v. 34, n. 7, p. 721, doi. 10.1038/nbt.3629

By:

Aiuti, Alessandro;
Naldini, Luigi

Publication type:

Article