Works matching AU Nakashima, Yu

Results: 29

A Tryptophan Prenyltransferase with Broad Substrate Tolerance from Bacillus subtilis subsp. natto.

Published in:

ChemBioChem, 2018, v. 19, n. 13, p. 1396, doi. 10.1002/cbic.201800174

By:

Sugita, Tomotoshi;
Okada, Masahiro;
Nakashima, Yu;
Tian, Tian;
Abe, Ikuro

Publication type:

Article

Physiological and Psychological Effects of Volatile Organic Compounds from Dried Common Rush (Juncus effusus L. var. decipiens Buchen.) on Humans.

Published in:

International Journal of Environmental Research & Public Health, 2022, v. 19, n. 3, p. 1856, doi. 10.3390/ijerph19031856

By:

Sun, Minkai;
Nakashima, Taisuke;
Yoshimura, Yuri;
Honden, Akiyoshi;
Nakagawa, Toshinori;
Nakashima, Yu;
Kawaguchi, Makoto;
Takamori, Yukimitsu;
Koshi, Yoshitaka;
Sawada, Rimpei;
Nishida, Shinsuke;
Ohnuki, Koichiro;
Shimizu, Kuniyoshi

Publication type:

Article

Human Oxygenase Variants Employing a Single Protein FeII Ligand Are Catalytically Active.

Published in:

Angewandte Chemie, 2021, v. 133, n. 26, p. 14778, doi. 10.1002/ange.202103711

By:

Brasnett, Amelia;
Pfeffer, Inga;
Brewitz, Lennart;
Chowdhury, Rasheduzzaman;
Nakashima, Yu;
Tumber, Anthony;
McDonough, Michael A.;
Schofield, Christopher J.

Publication type:

Article

Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-27971-z

By:

Wang, Xiao-Hui;
Gao, Bo-Wen;
Nakashima, Yu;
Mori, Takahiro;
Zhang, Zhong-Xiu;
Kodama, Takeshi;
Lee, Yuan-E;
Zhang, Ze-Kun;
Wong, Chin-Piow;
Liu, Qian-Qian;
Qi, Bo-Wen;
Wang, Juan;
Li, Jun;
Liu, Xiao;
Abe, Ikuro;
Morita, Hiroyuki;
Tu, Peng-Fei;
Shi, She-Po

Publication type:

Article

2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26673-2

By:

Nakashima, Yu;
Brewitz, Lennart;
Tumber, Anthony;
Salah, Eidarus;
Schofield, Christopher J.

Publication type:

Article

Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by ‘Entotheonella’.

Published in:

PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164468

By:

Nakashima, Yu;
Egami, Yoko;
Kimura, Miki;
Wakimoto, Toshiyuki;
Abe, Ikuro

Publication type:

Article

Phenolic Derivatives with Anti‐Acetylcholinesterase Inhibitory Activities from Galeola nudifolia in Vietnam.

Published in:

Chemistry & Biodiversity, 2023, v. 20, n. 12, p. 1, doi. 10.1002/cbdv.202301482

By:

Do, Kiep Minh;
Nakashima, Yu;
Kodama, Takeshi;
Lee, Yuan‐E;
Nguyen, Hien Minh;
Ikumi, Naotaka;
Morita, Hiroyuki

Publication type:

Article

Human Oxygenase Variants Employing a Single Protein FeII Ligand Are Catalytically Active.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 26, p. 14657, doi. 10.1002/anie.202103711

By:

Brasnett, Amelia;
Pfeffer, Inga;
Brewitz, Lennart;
Chowdhury, Rasheduzzaman;
Nakashima, Yu;
Tumber, Anthony;
McDonough, Michael A.;
Schofield, Christopher J.

Publication type:

Article

Innenrücktitelbild: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. 40/2024).

Published in:

Angewandte Chemie, 2024, v. 136, n. 40, p. 1, doi. 10.1002/ange.202414504

By:

Wu, Yue;
Chen, Yafen;
Corner, Thomas P.;
Nakashima, Yu;
Salah, Eidarus;
Li, Zhihong;
Zhang, Linjian;
Yang, Le;
Tumber, Anthony;
Sun, Zhuoli;
Wen, Yukang;
Zhong, Ailin;
Yang, Fulai;
Li, Xiang;
Zhang, Zhihong;
Schofield, Christopher J.;
Zhang, Xiaojin

Publication type:

Article

A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity.

Published in:

Angewandte Chemie, 2024, v. 136, n. 40, p. 1, doi. 10.1002/ange.202410438

By:

Wu, Yue;
Chen, Yafen;
Corner, Thomas P.;
Nakashima, Yu;
Salah, Eidarus;
Li, Zhihong;
Zhang, Linjian;
Yang, Le;
Tumber, Anthony;
Sun, Zhuoli;
Wen, Yukang;
Zhong, Ailin;
Yang, Fulai;
Li, Xiang;
Zhang, Zhihong;
Schofield, Christopher J.;
Zhang, Xiaojin

Publication type:

Article

Structure of lasso peptide epimerase MslH reveals metal-dependent acid/base catalytic mechanism.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40232-x

By:

Nakashima, Yu;
Kawakami, Atsushi;
Ogasawara, Yasushi;
Maeki, Masatoshi;
Tokeshi, Manabu;
Dairi, Tohru;
Morita, Hiroyuki

Publication type:

Article

Structural basis for binding of the renal carcinoma target hypoxia‐inducible factor 2α to prolyl hydroxylase domain 2.

Published in:

Proteins, 2023, v. 91, n. 11, p. 1510, doi. 10.1002/prot.26541

By:

Figg, William D.;
Fiorini, Giorgia;
Chowdhury, Rasheduzzaman;
Nakashima, Yu;
Tumber, Anthony;
McDonough, Michael A.;
Schofield, Christopher J.

Publication type:

Article

A human protein hydroxylase that accepts D-residues.

Published in:

Communications Chemistry, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42004-020-0290-5

By:

Choi, Hwanho;
Hardy, Adam P.;
Leissing, Thomas M.;
Chowdhury, Rasheduzzaman;
Nakashima, Yu;
Ge, Wei;
Markoulides, Marios;
Scotti, John S.;
Gerken, Philip A.;
Thorbjornsrud, Helen;
Kang, Dahye;
Hong, Sungwoo;
Lee, Joongoo;
McDonough, Michael A.;
Park, Hwangseo;
Schofield, Christopher J.

Publication type:

Article

Prevention of Acute Upper Respiratory Infections by Consumption of Catechins in Healthcare Workers: A Randomized, Placebo-Controlled Trial.

Published in:

Nutrients, 2020, v. 12, n. 1, p. 4, doi. 10.3390/nu12010004

By:

Furushima, Daisuke;
Nishimura, Takuma;
Takuma, Norikata;
Iketani, Ryo;
Mizuno, Tomohito;
Matsui, Yuji;
Yamaguchi, Tohru;
Nakashima, Yu;
Yamamoto, Shinji;
Hibi, Masanobu;
Yamada, Hiroshi

Publication type:

Article

Specific expression of MUC21 in micropapillary elements of lung adenocarcinomas – Implications for the progression of EGFR-mutated lung adenocarcinomas.

Published in:

PLoS ONE, 2019, v. 14, n. 4, p. 1, doi. 10.1371/journal.pone.0215237

By:

Matsumura, Mai;
Okudela, Koji;
Nakashima, Yu;
Mitsui, Hideaki;
Denda-Nagai, Kaori;
Suzuki, Takehisa;
Arai, Hiromasa;
Umeda, Shigeaki;
Tateishi, Yoko;
Koike, Chihiro;
Kataoka, Toshiaki;
Irimura, Tatsuro;
Ohashi, Kenichi

Publication type:

Article

Molecular Insight into the Mg2+‐Dependent Allosteric Control of Indole Prenylation by Aromatic Prenyltransferase AmbP1.

Published in:

Angewandte Chemie, 2018, v. 130, n. 23, p. 6926, doi. 10.1002/ange.201800855

By:

Awakawa, Takayoshi;
Mori, Takahiro;
Nakashima, Yu;
Zhai, Rui;
Wong, Chin Piow;
Hillwig, Matthew L.;
Liu, Xinyu;
Abe, Ikuro

Publication type:

Article

Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3.

Published in:

Angewandte Chemie, 2018, v. 130, n. 2, p. 569, doi. 10.1002/ange.201710682

By:

Wong, Chin Piow;
Awakawa, Takayoshi;
Nakashima, Yu;
Mori, Takahiro;
Zhu, Qin;
Liu, Xinyu;
Abe, Ikuro

Publication type:

Article

Which modality is better to diagnose high-grade transformation in retroperitoneal liposarcoma? Comparison of computed tomography, positron emission tomography, and magnetic resonance imaging.

Published in:

International Journal of Clinical Oncology, 2023, v. 28, n. 3, p. 482, doi. 10.1007/s10147-022-02287-6

By:

Nakashima, Yu;
Yokoyama, Yukihiro;
Ogawa, Hiroshi;
Sakakibara, Ayako;
Sunagawa, Masaki;
Nishida, Yoshihiro;
Mizuno, Takashi;
Yamaguchi, Junpei;
Onoe, Shunsuke;
Watanabe, Nobuyuki;
Kawakatsu, Shoji;
Igami, Tsuyoshi;
Ebata, Tomoki

Publication type:

Article

Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02371-w

By:

Yu Nakashima;
Takahiro Mori;
Hitomi Nakamura;
Takayoshi Awakawa;
Shotaro Hoshino;
Ikuro Abe;
Miki Senda;
Toshiya Senda

Publication type:

Article

Crystallographic and Selectivity Studies on the Approved HIF Prolyl Hydroxylase Inhibitors Desidustat and Enarodustat.

Published in:

ChemMedChem, 2024, v. 19, n. 24, p. 1, doi. 10.1002/cmdc.202400504

By:

Corner, Thomas P.;
Salah, Eidarus;
Tumber, Anthony;
Kaur, Samanpreet;
Nakashima, Yu;
Allen, Mark D.;
Schnaubelt, Lara I.;
Fiorini, Giorgia;
Brewitz, Lennart;
Schofield, Christopher J.

Publication type:

Article

Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat.

Published in:

ChemMedChem, 2021, v. 16, n. 13, p. 2082, doi. 10.1002/cmdc.202100133

By:

Figg, William D.;
McDonough, Michael A.;
Chowdhury, Rasheduzzaman;
Nakashima, Yu;
Zhang, Zhihong;
Holt‐Martyn, James P.;
Krajnc, Alen;
Schofield, Christopher J.

Publication type:

Article

Arginase inhibitory activities of guaiane sesquiterpenoids from Curcuma comosa rhizomes.

Published in:

Journal of Natural Medicines, 2023, v. 77, n. 4, p. 891, doi. 10.1007/s11418-023-01731-9

By:

Hoang, Nhat Nam;
Kodama, Takeshi;
Nakashima, Yu;
Do, Kiep Minh;
Hnin, Saw Yu Yu;
Lee, Yuan-E;
Prema;
Ikumi, Naotaka;
Morita, Hiroyuki

Publication type:

Article

Enzymatic formation of a prenyl β-carboline by a fungal indole prenyltransferase.

Published in:

Journal of Natural Medicines, 2022, v. 76, n. 4, p. 873, doi. 10.1007/s11418-022-01635-0

By:

Hamdy, Sherif Ahmed;
Kodama, Takeshi;
Nakashima, Yu;
Han, Xiaojie;
Matsui, Takashi;
Morita, Hiroyuki

Publication type:

Article

Molecular Insight into the Mg2+‐Dependent Allosteric Control of Indole Prenylation by Aromatic Prenyltransferase AmbP1.

Published in:

Angewandte Chemie International Edition, 2018, v. 57, n. 23, p. 6810, doi. 10.1002/anie.201800855

By:

Awakawa, Takayoshi;
Mori, Takahiro;
Nakashima, Yu;
Zhai, Rui;
Wong, Chin Piow;
Hillwig, Matthew L.;
Liu, Xinyu;
Abe, Ikuro

Publication type:

Article

Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3.

Published in:

Angewandte Chemie International Edition, 2018, v. 57, n. 2, p. 560, doi. 10.1002/anie.201710682

By:

Wong, Chin Piow;
Awakawa, Takayoshi;
Nakashima, Yu;
Mori, Takahiro;
Zhu, Qin;
Liu, Xinyu;
Abe, Ikuro

Publication type:

Article

Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont.

Published in:

Nature Chemical Biology, 2014, v. 10, n. 8, p. 648, doi. 10.1038/nchembio.1573

By:

Wakimoto, Toshiyuki;
Egami, Yoko;
Nakashima, Yu;
Wakimoto, Yukihiko;
Mori, Takahiro;
Awakawa, Takayoshi;
Ito, Takuya;
Kenmoku, Hiromichi;
Asakawa, Yoshinori;
Piel, Jörn;
Abe, Ikuro

Publication type:

Article

Using a Minimal Parameter Set for Early Diagnosis of Hemophagocytic Lymphohistiocytosis in Non-European Children.

Published in:

2022

By:

Yu Nakashima;
Hiroshi Koga

Publication type:

Case Study

Inside Back Cover: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. Int. Ed. 40/2024).

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 40, p. 1, doi. 10.1002/anie.202414504

By:

Wu, Yue;
Chen, Yafen;
Corner, Thomas P.;
Nakashima, Yu;
Salah, Eidarus;
Li, Zhihong;
Zhang, Linjian;
Yang, Le;
Tumber, Anthony;
Sun, Zhuoli;
Wen, Yukang;
Zhong, Ailin;
Yang, Fulai;
Li, Xiang;
Zhang, Zhihong;
Schofield, Christopher J.;
Zhang, Xiaojin

Publication type:

Article

A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 40, p. 1, doi. 10.1002/anie.202410438

By:

Wu, Yue;
Chen, Yafen;
Corner, Thomas P.;
Nakashima, Yu;
Salah, Eidarus;
Li, Zhihong;
Zhang, Linjian;
Yang, Le;
Tumber, Anthony;
Sun, Zhuoli;
Wen, Yukang;
Zhong, Ailin;
Yang, Fulai;
Li, Xiang;
Zhang, Zhihong;
Schofield, Christopher J.;
Zhang, Xiaojin

Publication type:

Article

Works matching AU Nakashima, Yu

A Tryptophan Prenyltransferase with Broad Substrate Tolerance from Bacillus subtilis subsp. natto.

Physiological and Psychological Effects of Volatile Organic Compounds from Dried Common Rush (Juncus effusus L. var. decipiens Buchen.) on Humans.

Human Oxygenase Variants Employing a Single Protein Fe<sup>II</sup> Ligand Are Catalytically Active.

Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood.

2-Oxoglutarate derivatives can selectively enhance or inhibit the activity of human oxygenases.

Metagenomic Analysis of the Sponge Discodermia Reveals the Production of the Cyanobacterial Natural Product Kasumigamide by ‘Entotheonella’.

Phenolic Derivatives with Anti‐Acetylcholinesterase Inhibitory Activities from Galeola nudifolia in Vietnam.

Human Oxygenase Variants Employing a Single Protein Fe<sup>II</sup> Ligand Are Catalytically Active.

Innenrücktitelbild: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. 40/2024).

A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity.

Structure of lasso peptide epimerase MslH reveals metal-dependent acid/base catalytic mechanism.

Structural basis for binding of the renal carcinoma target hypoxia‐inducible factor 2α to prolyl hydroxylase domain 2.

A human protein hydroxylase that accepts D-residues.

Prevention of Acute Upper Respiratory Infections by Consumption of Catechins in Healthcare Workers: A Randomized, Placebo-Controlled Trial.

Specific expression of MUC21 in micropapillary elements of lung adenocarcinomas – Implications for the progression of EGFR-mutated lung adenocarcinomas.

Molecular Insight into the Mg<sup>2+</sup>‐Dependent Allosteric Control of Indole Prenylation by Aromatic Prenyltransferase AmbP1.

Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3.

Which modality is better to diagnose high-grade transformation in retroperitoneal liposarcoma? Comparison of computed tomography, positron emission tomography, and magnetic resonance imaging.

Structure function and engineering of multifunctional non-heme iron dependent oxygenases in fungal meroterpenoid biosynthesis.

Crystallographic and Selectivity Studies on the Approved HIF Prolyl Hydroxylase Inhibitors Desidustat and Enarodustat.

Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat.

Arginase inhibitory activities of guaiane sesquiterpenoids from Curcuma comosa rhizomes.

Enzymatic formation of a prenyl β-carboline by a fungal indole prenyltransferase.

Molecular Insight into the Mg<sup>2+</sup>‐Dependent Allosteric Control of Indole Prenylation by Aromatic Prenyltransferase AmbP1.

Two Distinct Substrate Binding Modes for the Normal and Reverse Prenylation of Hapalindoles by the Prenyltransferase AmbP3.

Calyculin biogenesis from a pyrophosphate protoxin produced by a sponge symbiont.

Using a Minimal Parameter Set for Early Diagnosis of Hemophagocytic Lymphohistiocytosis in Non-European Children.

Inside Back Cover: A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity (Angew. Chem. Int. Ed. 40/2024).

A Small‐Molecule Inhibitor of Factor Inhibiting HIF Binding to a Tyrosine‐Flip Pocket for the Treatment of Obesity.