Works by Nakao, Ryuji

Results: 28

Quality control of PET radiopharmaceuticals by high-performance liquid chromatography with tris(2,2′-bipyridyl)ruthenium(II) electrogenerated chemiluminescence detection.

Published in:

Biomedical Chromatography, 2010, v. 24, n. 2, p. 202, doi. 10.1002/bmc.1274

By:

Nakao, Ryuji;
Furutsuka, Kenji;
Fukumura, Toshimitsu;
Yamaguchi, Masatoshi;
Suzuki, Kazutoshi

Publication type:

Article

In vivo mapping of substance P receptors in brains of laboratory animals by high-resolution imaging systems.

Published in:

Synapse, 2007, v. 61, n. 4, p. 205, doi. 10.1002/syn.20363

By:

Haneda, Eisuke;
Higuchi, Makoto;
Maeda, Jun;
Inaji, Motoki;
Okauchi, Takashi;
Ando, Kiyoshi;
Obayashi, Shigeru;
Nagai, Yuji;
Narazaki, Michiko;
Ikehira, Hiroo;
Nakao, Ryuji;
Zhang, Ming-Rong;
Suzuki, Kazutoshi;
Suzuki, Hidenori;
Suhara, Tetsuya

Publication type:

Article

Identification of PET radiometabolites by cytochrome P450, UHPLC/Q-ToF-MS and fast radio-LC: applied to the PET radioligands [C]flumazenil, [F]FE-PE2I, and [C]PBR28.

Published in:

Analytical & Bioanalytical Chemistry, 2013, v. 405, n. 4, p. 1303, doi. 10.1007/s00216-012-6541-2

By:

Amini, Nahid;
Nakao, Ryuji;
Schou, Magnus;
Halldin, Christer

Publication type:

Article

A Nonhuman Primate PET Study: Measurement of Brain PDE4 Occupancy by Roflumilast Using (R)-[11C]Rolipram.

Published in:

2018

By:

Takano, Akihiro;
Uz, Tolga;
Garcia-Segovia, Jesus;
Tsai, Max;
Lahu, Gezim;
Amini, Nahid;
Nakao, Ryuji;
Jia, Zhisheng;
Halldin, Christer

Publication type:

journal article

Molecular Imaging of PDE10A Knockout Mice with a Novel PET Radiotracer: [(11)C]T-773.

Published in:

2015

By:

Tóth, Miklós;
Häggkvist, Jenny;
Stepanov, Vladimir;
Takano, Akihiro;
Nakao, Ryuji;
Amini, Nahid;
Miura, Shotaro;
Kimura, Haruhide;
Taniguchi, Takahiko;
Gulyás, Balázs;
Halldin, Christer

Publication type:

journal article

Molecular Imaging of PDE10A Knockout Mice with a Novel PET Radiotracer: [C]T-773.

Published in:

Molecular Imaging & Biology, 2015, v. 17, n. 4, p. 445, doi. 10.1007/s11307-015-0822-z

By:

Tóth, Miklós;
Häggkvist, Jenny;
Stepanov, Vladimir;
Takano, Akihiro;
Nakao, Ryuji;
Amini, Nahid;
Miura, Shotaro;
Kimura, Haruhide;
Taniguchi, Takahiko;
Gulyás, Balázs;
Halldin, Christer

Publication type:

Article

Synthesis, radiolabeling, and in vivo pharmacokinetic evaluation of the amyloid beta radioligand [11C]AZD4694 in nonhuman primates.

Published in:

2014

By:

Schou, Magnus;
Varnäs, Katarina;
Sandell, Johan;
Johnström, Peter;
Cselenyi, Zsolt;
Svensson, Samuel;
Nakao, Ryuji;
Amini, Nahid;
Bergman, Linda;
Sumic, Anna;
Gulyas, Balazs;
Lindström-Böö, Eva;
Halldin, Christer;
Farde, Lars

Publication type:

journal article

Synthesis, Radiolabeling, and In Vivo Pharmacokinetic Evaluation of the Amyloid Beta Radioligand [C]AZD4694 in Nonhuman Primates.

Published in:

Molecular Imaging & Biology, 2014, v. 16, n. 2, p. 173, doi. 10.1007/s11307-013-0666-3

By:

Schou, Magnus;
Varnäs, Katarina;
Sandell, Johan;
Johnström, Peter;
Cselenyi, Zsolt;
Svensson, Samuel;
Nakao, Ryuji;
Amini, Nahid;
Bergman, Linda;
Sumic, Anna;
Gulyas, Balazs;
Lindström-Böö, Eva;
Halldin, Christer;
Farde, Lars

Publication type:

Article

Amphetamine Decreases α2C-Adrenoceptor Binding of [11C]ORM-13070: A PET Study in the Primate Brain.

Published in:

International Journal of Neuropsychopharmacology, 2015, v. 18, n. 3, p. 1, doi. 10.1093/ijnp/pyu081

By:

Finnema, Sjoerd J;
Hughes, Zoë A;
Haaparanta-Solin, Merja;
Stepanov, Vladimir;
Nakao, Ryuji;
Varnäs, Katarina;
Varrone, Andrea;
Arponen, Eveliina;
Marjamäki, Päivi;
Pohjanoksa, Katariina;
Vuorilehto, Lauri;
Babalola, Phebian A;
Solin, Olof;
Grimwood, Sarah;
Sallinen, Jukka;
Farde, Lars;
Scheinin, Mika;
Halldin, Christer

Publication type:

Article

Quantitative Analysis of 18F-(E)-N-(3-Iodoprop-2-Enyl)-2β Carbofluoroethoxy-3β-(4'-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease.

Published in:

Journal of Nuclear Medicine, 2015, v. 56, n. 5, p. 714, doi. 10.2967/jnumed.114.152421

By:

Fazio, Patrik;
Svenningsson, Per;
Forsberg, Anton;
Jönsson, Erik G.;
Amini, Nahid;
Nakao, Ryuji;
Nag, Sangram;
Halldin, Christer;
Farde, Lars;
Varrone, Andrea

Publication type:

Article

18F-MCL-524, an 18F-Labeled Dopamine D2 and D3 Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study.

Published in:

Journal of Nuclear Medicine, 2014, v. 55, n. 7, p. 1164, doi. 10.2967/jnumed.113.133876

By:

Finnema, Sjoerd J.;
Stepano, Vladimir;
Ryuji Nakao;
Sromek, Anna W.;
Zhang, Tangzhi;
Neumeyer, John L.;
George, Susan R.;
Seeman, Philip;
Stabin, Michael G.;
Jonsson, Cathrine;
Farde, Lars;
Halldin, Christer

Publication type:

Article

Quantification of Dopamine Transporter in Human Brain Using PET with 18F-FE-PE2I.

Published in:

Journal of Nuclear Medicine, 2012, v. 53, n. 7, p. 1065, doi. 10.2967/jnumed.111.101626

By:

Sasaki, Takeshi;
Ito, Hiroshi;
Kimura, Yasuyuki;
Arakawa, Ryosuke;
Takano, Harumasa;
Seki, Chie;
Kodaka, Fumitoshi;
Fujie, Saori;
Takahata, Keisuke;
Nogami, Tsuyoshi;
Suzuki, Masayuki;
Fujiwara, Hironobu;
Takahashit, Hidehiko;
Nakao, Ryuji;
Fukumura, Toshimitsu;
Varrone, Andrea;
Halldin, Christer;
Nishikawa, Toru;
Suhara, Tetsuya

Publication type:

Article

Imaging of the Striatal and Extrastriatal Dopamine Transporter with 18F-LBT-999: Quantification, Biodistribution, and Radiation Dosimetry in Nonhuman Primates.

Published in:

Journal of Nuclear Medicine, 2011, v. 52, n. 8, p. 1313, doi. 10.2967/jnumed.111.089953

By:

Varrone, Andrea;
Stepanov, Vladimir;
Nakao, Ryuji;
Tóth, Miklós;
Gulyás, Balázs;
Emond, Patrik;
Deloye, Jean Bernard;
Vercouillie, Johnny;
Stabin, Michael G.;
Jonsson, Cathrine;
Guilloteau, Denis;
Halldin, Christer

Publication type:

Article

Quantitative Analysis of Peripheral Benzodiazepine Receptor in the Human Brain Using PET with 11C-AC-5216.

Published in:

Journal of Nuclear Medicine, 2009, v. 50, n. 7, p. 1095, doi. 10.2967/jnumed.109.062554

By:

Miyoshi, Michie;
Ito, Hiroshi;
Arakawa, Ryosuke;
Takahashi, Hidehiko;
Takano, Harumasa;
Higuchi, Makoto;
Okumura, Masaki;
Otsuka, Tatsui;
Kodaka, Fumitoshi;
Sekine, Mizuho;
Sasaki, Takeshi;
Fujie, Saori;
Seki, Chie;
Maeda, Jun;
Nakao, Ryuji;
Ming-Rong Zhang;
Fukumura, Toshimitsu;
Matsumoto, Masayasu;
Suhara, Tetsuya

Publication type:

Article

Quantitative PET Analysis of the Dopamine D2 Receptor Agonist Radioligand 11C-(R)-2-CH3O-N-n-Propylnorapomorphine in the Human Brain.

Published in:

Journal of Nuclear Medicine, 2009, v. 50, n. 5, p. 703, doi. 10.2967/jnumed.108.058503

By:

Otsuka, Tatsui;
Ito, Hiroshi;
Halldin, Christer;
Takahashi, Hidehiko;
Takano, Harumasa;
Arakawa, Ryosuke;
Okumura, Masaki;
Kodaka, Fumitoshi;
Miyoshi, Michie;
Sekine, Mizuho;
Seki, Chie;
Nakao, Ryuji;
Suzuki, Kazutoshi;
Finnema, Sjoerd;
Hirayasu, Yoshio;
Suhara, Tetsuya;
Farde, Lars

Publication type:

Article

Quantitative Analysis of NK1 Receptor in the Human Brain Using PET with 18F-FE-SPA-RQ.

Published in:

Journal of Nuclear Medicine, 2008, v. 49, n. 11, p. 1749, doi. 10.2967/jnumed.108.054353

By:

Okumura, Masaki;
Arakawa, Ryosuke;
Ito, Hiroshi;
Seki, Chie;
Takahashi, Hidehiko;
Takano, Harumasa;
Haneda, Eisuke;
Nakao, Ryuji;
Suzuki, Hidenori;
Suzuki, Kazutoshi;
Okubo, Yoshiro;
Suhara, Tetsuya

Publication type:

Article

Quantitative Analysis of Norepinephrine Transporter in the Human Brain Using PET with (S,S)-18F-FMeNER-D2.

Published in:

Journal of Nuclear Medicine, 2008, v. 49, n. 8, p. 1270, doi. 10.2967/jnumed.108.051292

By:

Arakawa, Ryosuke;
Okumura, Masaki;
Ito, Hiroshi;
Seki, Chie;
Takahashi, Hidehiko;
Takano, Harumasa;
Nakao, Ryuji;
Suzuki, Kazutoshi;
Okubo, Yoshiro;
Halldin, Christer;
Suhara, Tetsuya

Publication type:

Article

Quantitative Analysis of 11C-Verapamil Transfer at the Human Blood--Brain Barrier for Evaluation of P-glycoprotein Function.

Published in:

Journal of Nuclear Medicine, 2006, v. 47, n. 9, p. 1531

By:

Ikoma, Yoko;
Takano, Akihiro;
Ito, Hiroshi;
Kusuhara, Hiroyuki;
Sugiyama, Yuichi;
Arakawa, Ryosuke;
Fukumura, Toshimitsu;
Nakao, Ryuji;
Suzuki, Kazutoshi;
Suhara, Tetsuya

Publication type:

Article

Quantitative Analyses of 18F-FEDAA1106 Binding to Peripheral Benzodiazepine Receptors in Living Human Brain.

Published in:

Journal of Nuclear Medicine, 2006, v. 47, n. 1, p. 43

By:

Fujimura, Yota;
Ikoma, Yoko;
Yasuno, Fumihiko;
Suhara, Tetsuya;
Ota, Miho;
Matsumoto, Ryohei;
Nozaki, Shoko;
Takano, Akihiro;
Kosaka, Jun;
Zhang, Ming-Rong;
Nakao, Ryuji;
Suzuki, Kazutoshi;
Kato, Nobumasa;
Ito, Hiroshi

Publication type:

Article

Positron emission tomography measurement of brain MAO-B inhibition in patients with Alzheimer's disease and elderly controls after oral administration of sembragiline.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2017, v. 44, n. 3, p. 382, doi. 10.1007/s00259-016-3510-6

By:

Sturm, Stefan;
Forsberg, Anton;
Nave, Stephane;
Stenkrona, Per;
Seneca, Nicholas;
Varrone, Andrea;
Comley, Robert;
Fazio, Patrik;
Jamois, Candice;
Nakao, Ryuji;
Ejduk, Zbigniew;
Al-Tawil, Nabil;
Akenine, Ulrika;
Halldin, Christer;
Andreasen, Niels;
Ricci, Benedicte

Publication type:

Article

Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [F]FEMPA in Alzheimer's disease patients and control subjects.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2015, v. 42, n. 3, p. 438, doi. 10.1007/s00259-014-2955-8

By:

Varrone, Andrea;
Oikonen, Vesa;
Forsberg, Anton;
Joutsa, Juho;
Takano, Akihiro;
Solin, Olof;
Haaparanta-Solin, Merja;
Nag, Sangram;
Nakao, Ryuji;
Al-Tawil, Nabil;
Wells, Lisa;
Rabiner, Eugenii;
Valencia, Ray;
Schultze-Mosgau, Marcus;
Thiele, Andrea;
Vollmer, Sonja;
Dyrks, Thomas;
Lehmann, Lutz;
Heinrich, Tobias;
Hoffmann, Anja

Publication type:

Article

Radiolabeling and Preliminary In Vivo Evaluation of the Candidate CCR2 Targeting PET Radioligand [ 11 C]AZD2423.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 2, p. 135, doi. 10.3390/ph18020135

By:

Dahl, Kenneth;
Johnström, Peter;
Tóth, Miklós;
Bolin, Martin;
Varnäs, Katarina;
Nakao, Ryuji;
Takano, Akihiro;
Khani Meynaq, Yasir;
Bayrakdarian, Malken;
Cselényi, Zsolt;
Halldin, Christer;
Farde, Lars;
Schou, Magnus

Publication type:

Article

Brain PET measurement of PDE10A occupancy by TAK-063, a new PDE10A inhibitor, using [11C]T-773 in nonhuman primates.

Published in:

Synapse, 2016, v. 70, n. 6, p. 253, doi. 10.1002/syn.21896

By:

Takano, Akihiro;
Stepanov, Vladimir;
Nakao, Ryuji;
Amini, Nahid;
Gulyás, Balázs;
Kimura, Haruhide;
Halldin, Christer

Publication type:

Article

Evaluation of a novel PDE10 A PET radioligand, [11 C] T-773, in nonhuman primates: Brain and whole body PET and brain autoradiography.

Published in:

Synapse, 2015, v. 69, n. 7, p. 345, doi. 10.1002/syn.21821

By:

Takano, Akihiro;
Stepanov, Vladimir;
Gulyás, Balázs;
Nakao, Ryuji;
Amini, Nahid;
Miura, Shotaro;
Kimura, Haruhide;
Taniguchi, Takahiko;
Halldin, Christer

Publication type:

Article

Neuroimaging and Physiological Evidence for Involvement of Glutamatergic Transmission in Regulation of the Striatal Dopaminergic System.

Published in:

Journal of Neuroscience, 2009, v. 29, n. 6, p. 1887, doi. 10.1523/JNEUROSCI.2559-08.2009

By:

Tokunaga, Masaki;
Seneca, Nicholas;
Ryong-Moon Shin;
Maeda, Jun;
Obayashi, Shigeru;
Okauchi, Takashi;
Nagai, Yuji;
Ming-Rong Zhang;
Nakao, Ryuji;
Ito, Hiroshi;
Innis, Robert B.;
Halldin, Christer;
Suzuki, Kazutoshi;
Higuchi, Makoto;
Suhara, Tetsuya

Publication type:

Article

Microdialysis with radiometric monitoring of L-[β-11C]DOPA to assess dopaminergic metabolism: effect of inhibitors of L-amino acid decarboxylase, monoamine oxidase, and catechol-O-methyltransferase on rat striatal dialysate.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2011, v. 31, n. 1, p. 124, doi. 10.1038/jcbfm.2010.58

By:

Okada, Maki;
Nakao, Ryuji;
Hosoi, Rie;
Zhang, Ming-Rong;
Fukumura, Toshimitsu;
Suzuki, Kazutoshi;
Inoue, Osamu

Publication type:

Article

Quantitative analysis for estimating binding potential of the peripheral benzodiazepine receptor with [11C]DAA1106.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2007, v. 27, n. 1, p. 173, doi. 10.1038/sj.jcbfm.9600325

By:

Ikoma, Yoko;
Yasuno, Fumihiko;
Ito, Hiroshi;
Suhara, Tetsuya;
Ota, Miho;
Toyama, Hinako;
Fujimura, Yota;
Takano, Akihiro;
Maeda, Jun;
Ming-Rong Zhang;
Nakao, Ryuji;
Suzuki, Kazutoshi

Publication type:

Article

Development of a series of novel carbon-11 labeled PDE10A inhibitors.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2015, v. 58, n. 5, p. 202, doi. 10.1002/jlcr.3284

By:

Stepanov, Vladimir;
Miura, Shotaro;
Takano, Akihiro;
Amini, Nahid;
Nakao, Ryuji;
Hasui, Tomoaki;
Nakashima, Kosuke;
Taniguchi, Takahiko;
Kimura, Haruhide;
Kuroita, Takanobu;
Halldin, Christer

Publication type:

Article

Works by Nakao, Ryuji

Quality control of PET radiopharmaceuticals by high-performance liquid chromatography with tris(2,2′-bipyridyl)ruthenium(II) electrogenerated chemiluminescence detection.

In vivo mapping of substance P receptors in brains of laboratory animals by high-resolution imaging systems.

Identification of PET radiometabolites by cytochrome P450, UHPLC/Q-ToF-MS and fast radio-LC: applied to the PET radioligands [C]flumazenil, [F]FE-PE2I, and [C]PBR28.

A Nonhuman Primate PET Study: Measurement of Brain PDE4 Occupancy by Roflumilast Using (R)-[<sup>11</sup>C]Rolipram.

Molecular Imaging of PDE10A Knockout Mice with a Novel PET Radiotracer: [(11)C]T-773.

Molecular Imaging of PDE10A Knockout Mice with a Novel PET Radiotracer: [C]T-773.

Synthesis, radiolabeling, and in vivo pharmacokinetic evaluation of the amyloid beta radioligand [11C]AZD4694 in nonhuman primates.

Synthesis, Radiolabeling, and In Vivo Pharmacokinetic Evaluation of the Amyloid Beta Radioligand [C]AZD4694 in Nonhuman Primates.

Amphetamine Decreases α2C-Adrenoceptor Binding of [11C]ORM-13070: A PET Study in the Primate Brain.

Quantitative Analysis of <sup>18</sup>F-(E)-N-(3-Iodoprop-2-Enyl)-2β Carbofluoroethoxy-3β-(4'-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease.

<sup>18</sup>F-MCL-524, an <sup>18</sup>F-Labeled Dopamine D<sub>2</sub> and D<sub>3</sub> Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study.

Quantification of Dopamine Transporter in Human Brain Using PET with <sup>18</sup>F-FE-PE2I.

Imaging of the Striatal and Extrastriatal Dopamine Transporter with <sup>18</sup>F-LBT-999: Quantification, Biodistribution, and Radiation Dosimetry in Nonhuman Primates.

Quantitative Analysis of Peripheral Benzodiazepine Receptor in the Human Brain Using PET with <sup>11</sup>C-AC-5216.

Quantitative PET Analysis of the Dopamine D<sub>2</sub> Receptor Agonist Radioligand <sup>11</sup>C-(R)-2-CH<sub>3</sub>O-N-n-Propylnorapomorphine in the Human Brain.

Quantitative Analysis of NK<sub>1</sub> Receptor in the Human Brain Using PET with <sup>18</sup>F-FE-SPA-RQ.

Quantitative Analysis of Norepinephrine Transporter in the Human Brain Using PET with (S,S)-<sup>18</sup>F-FMeNER-D<sub>2</sub>.

Quantitative Analysis of <sup>11</sup>C-Verapamil Transfer at the Human Blood--Brain Barrier for Evaluation of P-glycoprotein Function.

Quantitative Analyses of <sup>18</sup>F-FEDAA1106 Binding to Peripheral Benzodiazepine Receptors in Living Human Brain.

Positron emission tomography measurement of brain MAO-B inhibition in patients with Alzheimer's disease and elderly controls after oral administration of sembragiline.

Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [F]FEMPA in Alzheimer's disease patients and control subjects.

Radiolabeling and Preliminary In Vivo Evaluation of the Candidate CCR2 Targeting PET Radioligand [ 11 C]AZD2423.

Brain PET measurement of PDE10A occupancy by TAK-063, a new PDE10A inhibitor, using [<sup>11</sup>C]T-773 in nonhuman primates.

Evaluation of a novel PDE10 A PET radioligand, [<sup>11</sup> C] T-773, in nonhuman primates: Brain and whole body PET and brain autoradiography.

Neuroimaging and Physiological Evidence for Involvement of Glutamatergic Transmission in Regulation of the Striatal Dopaminergic System.

Microdialysis with radiometric monitoring of L-[β-<sup>11</sup>C]DOPA to assess dopaminergic metabolism: effect of inhibitors of L-amino acid decarboxylase, monoamine oxidase, and catechol-O-methyltransferase on rat striatal dialysate.

Quantitative analysis for estimating binding potential of the peripheral benzodiazepine receptor with [<sup>11</sup>C]DAA1106.

Development of a series of novel carbon-11 labeled PDE10A inhibitors.