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Combination of monoammonium glycyrrhizinate and cysteine hydrochloride protects mice against acetaminophen-induced liver injury via Keap1/Nrf2/ARE pathway.
Published in:
Journal of Pharmacy & Pharmacology, 2022, v. 74, n. 5, p. 730, doi. 10.1093/jpp/rgab180
By:
- Li, Juntong;
- Gao, Yan;
- Cui, Liyuan;
- He, Hongyuan;
- Zheng, Jianyong;
- Mo, Shu;
- Zhou, Xin;
- Chu, Shifeng;
- Sun, Xiaoyun;
- Chen, Naihong;
- Wang, Hong
Publication type:
Article
Ginsenoside Rg3 ameliorates acetaminophen-induced hepatotoxicity by suppressing inflammation and oxidative stress.
Published in:
Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 3, p. 322, doi. 10.1093/jpp/rgaa069
By:
- Yan Gao;
- Jiaqing Yan;
- Juntong Li;
- Xun Li;
- Songwei Yang;
- Naihong Chen;
- Lin Li;
- Lan Zhang
Publication type:
Article
Insight into Medicinal Chemistry Behind Traditional Chinese Medicines: p-Hydroxybenzyl Alcohol-Derived Dimers and Trimers from Gastrodia elata.
Published in:
Natural Products & Bioprospecting, 2021, v. 11, n. 1, p. 31, doi. 10.1007/s13659-020-00258-w
By:
- Wang, Yanan;
- Zhang, Min;
- Zhou, Xue;
- Xu, Chengbo;
- Zhu, Chenggen;
- Yuan, Yuhe;
- Chen, Naihong;
- Yang, Yongchun;
- Guo, Qinglan;
- Shi, Jiangong
Publication type:
Article
A Review of Research on the Association between Neuron–Astrocyte Signaling Processes and Depressive Symptoms.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 8, p. 6985, doi. 10.3390/ijms24086985
By:
- Yao, Jiao;
- Chen, Cong;
- Guo, Yi;
- Yang, Yantao;
- Liu, Xinya;
- Chu, Shifeng;
- Ai, Qidi;
- Zhang, Zhao;
- Lin, Meiyu;
- Yang, Songwei;
- Chen, Naihong
Publication type:
Article
Novel Antidepressant Mechanism of Ginsenoside Rg1 in Regulating the Dysfunction of the Glutamatergic System in Astrocytes.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 575, doi. 10.3390/ijms24010575
By:
- Zhang, Ningning;
- Jiang, Hong;
- Wang, Huiqin;
- Wang, Yating;
- Peng, Ye;
- Liu, Yangbo;
- Xia, Congyuan;
- Yan, Xu;
- Chu, Shifeng;
- Zhang, Yi;
- Wang, Zhenzhen;
- Chen, Naihong
Publication type:
Article
IMM-H004 Protects against Cerebral Ischemia Injury and Cardiopulmonary Complications via CKLF1 Mediated Inflammation Pathway in Adult and Aged Rats.
Published in:
International Journal of Molecular Sciences, 2019, v. 20, n. 7, p. 1661, doi. 10.3390/ijms20071661
By:
- Ai, Qidi;
- Chen, Naihong;
- Chen, Chen;
- Chu, Shifeng;
- Zhang, Zhao;
- Zhang, Shuai;
- Yang, Pengfei;
- Gao, Yan;
- Zhang, Xiaoling;
- Luo, Yun
Publication type:
Article
The mechanism of programmed death and endoplasmic reticulum stress in pulmonary hypertension.
Published in:
Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01373-6
By:
- Sun, Yang;
- Liu, Shasha;
- Chen, Chen;
- Yang, Songwei;
- Pei, Gang;
- Lin, Meiyu;
- Wang, Ting;
- Long, Junpeng;
- Yan, Qian;
- Yao, Jiao;
- Lin, Yuting;
- Yi, Fan;
- Meng, Lei;
- Tan, Yong;
- Ai, Qidi;
- Chen, Naihong;
- Yang, Yantao
Publication type:
Article
CZK, a novel alkaloid derivative from Clausena lansium, alleviates ischemic stroke injury through Nrf2-mediated antioxidant effects.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-32999-2
By:
- Chen, Haodong;
- Liu, Yangbo;
- Feng, Juling;
- Wang, Hongyun;
- Yang, Yantao;
- Ai, Qidi;
- Zhang, Zhao;
- Chu, Shifeng;
- Chen, Naihong
Publication type:
Article
New perspective on sustained antidepressant effect: focus on neurexins regulating synaptic plasticity.
Published in:
Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01974-9
By:
- Ruan, Yuan;
- Yuan, Ruolan;
- He, Jiaqi;
- Jiang, Yutong;
- Chu, Shifeng;
- Chen, Naihong
Publication type:
Article
Targeting pyroptosis as a preventive and therapeutic approach for stroke.
Published in:
Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01440-y
By:
- Long, Junpeng;
- Sun, Yang;
- Liu, Shasha;
- Yang, Songwei;
- Chen, Chen;
- Zhang, Zhao;
- Chu, Shifeng;
- Yang, Yantao;
- Pei, Gang;
- Lin, Meiyu;
- Yan, Qian;
- Yao, Jiao;
- Lin, Yuting;
- Yi, Fan;
- Meng, Lei;
- Tan, Yong;
- Ai, Qidi;
- Chen, Naihong
Publication type:
Article
Mechanism of Dihydromyricetin on Inflammatory Diseases.
Published in:
Frontiers in Pharmacology, 2022, v. 12, p. 1, doi. 10.3389/fphar.2021.794563
By:
- Sun, Yang;
- Liu, Shasha;
- Yang, Songwei;
- Chen, Chen;
- Yang, Yantao;
- Lin, Meiyu;
- Liu, Chao;
- Wang, Wenmao;
- Zhou, Xudong;
- Ai, Qidi;
- Wang, Wei;
- Chen, Naihong
Publication type:
Article
Ginsenoside Rg1 Ameliorates Neuroinflammation via Suppression of Connexin43 Ubiquitination to Attenuate Depression.
Published in:
Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.709019
By:
- Wang, Huiqin;
- Yang, Yantao;
- Yang, Songwei;
- Ren, Siyu;
- Feng, Juling;
- Liu, Yangbo;
- Chen, Haodong;
- Chen, Naihong
Publication type:
Article
The Anti-Neuroinflammatory Effect of Fuzi and Ganjiang Extraction on LPS-Induced BV2 Microglia and Its Intervention Function on Depression-Like Behavior of Cancer-Related Fatigue Model Mice.
Published in:
Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.670586
By:
- Yang, Songwei;
- Yang, Yantao;
- Chen, Cong;
- Wang, Huiqin;
- Ai, Qidi;
- Lin, Meiyu;
- Zeng, Qi;
- Zhang, Yi;
- Gao, Yan;
- Li, Xun;
- Chen, Naihong
Publication type:
Article
Neuroinflammatory In Vitro Cell Culture Models and the Potential Applications for Neurological Disorders.
Published in:
Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.671734
By:
- Peng, Ye;
- Chu, Shifeng;
- Yang, Yantao;
- Zhang, Zhao;
- Pang, Zongran;
- Chen, Naihong
Publication type:
Article
Tyrosine 402 Phosphorylation of Pyk2 Is Involved in Ionomycin-Induced Neurotransmitter Release.
Published in:
PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0094574
By:
- Zhang, Zhao;
- Zhang, Yun;
- Mou, Zheng;
- Chu, Shifeng;
- Chen, Xiaoyu;
- He, Wenbin;
- Guo, Xiaofeng;
- Yuan, Yuhe;
- Takahashi, Masami;
- Chen, Naihong
Publication type:
Article
Comparative Proteomic Characterization of Ventral Hippocampus in Susceptible and Resilient Rats Subjected to Chronic Unpredictable Stress.
Published in:
Frontiers in Neuroscience, 2021, p. 1, doi. 10.3389/fnins.2021.675430
By:
- Zhang, Yani;
- Zhang, Xiaoling;
- Liu, Nuo;
- Ren, Siyu;
- Xia, Congyuan;
- Yang, Xiong;
- Lou, Yuxia;
- Wang, Huiqin;
- Zhang, Ningning;
- Yan, Xu;
- Zhang, Zhao;
- Zhang, Yi;
- Wang, Zhenzhen;
- Chen, Naihong
Publication type:
Article
Efficacy of Lidan Tang on high-fat-diet induced gallstone in mice and possible mechanism.
Published in:
Journal of Traditional Chinese Medicine, 2020, v. 40, n. 4, p. 584
By:
- Gao Yan;
- Liu Caipin;
- Li Juntong;
- Zhai Yingying;
- Lin Meiyu;
- Wu Qinglin;
- Chu Shifeng;
- Zhang Zhao;
- Li Jianping;
- Zhou Xin;
- Li Yueting;
- Chen Naihong
Publication type:
Article
Antidepressant-like effect of active fraction of Polyrhachisvicina Roger in a rat depression model.
Published in:
Journal of Traditional Chinese Medicine, 2018, v. 38, n. 1, p. 12, doi. 10.1016/j.jtcm.2018.02.001
By:
- Wei Guining;
- Chu Shifeng;
- Su Qibiao;
- Su Hua;
- Lin Meiyu;
- He Fei;
- Lu Wenjie;
- Lu Guoshou;
- Huang Zhoufeng;
- Tan Xiao;
- Lin Xiao;
- Zeng Xianbiao;
- Wei Baowei;
- Chen Naihong
Publication type:
Article
Protein kinase-based neural signaling pathways for ginsenosides: a retrospective review.
Published in:
Journal of Traditional Chinese Medicine, 2015, v. 35, n. 3, p. 349, doi. 10.1016/s0254-6272(15)30109-6
By:
- He Wenbin;
- Zhang Junlong;
- Chen Naihong
Publication type:
Article
Liposoluble constituents from lodes cirrhosa and their neuroprotective and potassium channel-blocking activity.
Published in:
China Journal of Chinese Materia Medica, 2011, v. 36, n. 9, p. 1183, doi. 10.4268/cjcmm20110916
By:
- GAN Maoluo;
- LIN Sheng;
- ZHANG Yanling;
- ZI Jiachen;
- Song Weixia;
- Hu Jinfeng;
- Chen Naihong;
- Wang Ling;
- Wang Xiaoliang;
- Shi Jiangong
Publication type:
Article
Aromatic constituents of Heteroplexis micocephal and their bioactivities.
Published in:
China Journal of Chinese Materia Medica, 2011, v. 36, n. 1, p. 48, doi. 10.4268/cjcmm20110111
By:
- FAN Xiaona;
- LIN Sheng;
- ZHU Chenggen;
- LIU Yang;
- HU Jinfeng;
- CHEN Xiaoguang;
- WANG Wenjie;
- CHEN Naihong;
- SHI Jiangong
Publication type:
Article
Chemical constituents of stems and branches of Adina polycephala.
Published in:
China Journal of Chinese Materia Medica, 2010, v. 35, n. 10, p. 1261, doi. 10.4268/cjcmm20101010
By:
- ZHANG Yanling;
- CAN Maoluo;
- LI Shuai;
- WANG Sujuan;
- ZHU Chenggen;
- YANG Yongchun;
- HU Jinfeng;
- CHEN Naihong;
- SHI Jiangong
Publication type:
Article
Targeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease.
Published in:
Journal of Translational Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12967-023-04361-7
By:
- Yan, Qian;
- Liu, Shasha;
- Sun, Yang;
- Chen, Chen;
- Yang, Songwei;
- Lin, Meiyu;
- Long, Junpeng;
- Yao, Jiao;
- Lin, Yuting;
- Yi, Fan;
- Meng, Lei;
- Tan, Yong;
- Ai, Qidi;
- Chen, Naihong;
- Yang, Yantao
Publication type:
Article
Early Stage Functions of Mitochondrial Autophagy and Oxidative Stress in Acetaminophen-Induced Liver Injury.
Published in:
Journal of Cellular Biochemistry, 2017, v. 118, n. 10, p. 3130, doi. 10.1002/jcb.25788
By:
- Gao, Yan;
- Chu, Shifeng;
- Zhang, Zhao;
- Zuo, Wei;
- Xia, Congyuan;
- Ai, Qidi;
- Luo, Piao;
- Cao, Peng;
- Chen, Naihong
Publication type:
Article
Hypouricemic and Nephroprotective Effects of an Active Fraction from <bold><italic>Polyrhachis Vicina Roger</italic></bold> On Potassium Oxonate-Induced Hyperuricemia in Rats.
Published in:
Kidney & Blood Pressure Research, 2018, v. 43, n. 1, p. 220, doi. 10.1159/000487675
By:
- Su, Qibiao;
- Su, Hua;
- Nong, Zhihuan;
- Li, Dongmei;
- Wang, Laiyou;
- Chu, Shifeng;
- Liao, Lizhen;
- Zhao, Jie;
- Zeng, Xianbiao;
- Ya, Qikang;
- He, Fei;
- Lu, Wenjie;
- Wei, Baowei;
- Wei, Guining;
- Chen, Naihong
Publication type:
Article
Mahonia Alkaloids (MA) Ameliorate Depression Induced Gap Junction Dysfunction by miR-205/Cx43 Axis.
Published in:
Neurochemical Research, 2022, v. 47, n. 12, p. 3761, doi. 10.1007/s11064-022-03761-3
By:
- He, Junhui;
- Li, Dongmei;
- Wei, Jie;
- Wang, Sheng;
- Chu, Shifeng;
- Zhang, Zhao;
- He, Fei;
- Wei, Dongmei;
- Li, Yi;
- Xie, Jiaxiu;
- Lai, Kedao;
- Chen, Naihong;
- Wei, Guining
Publication type:
Article
Neuroprotective Effects of Anthraquinones from Rhubarb in Central Nervous System Diseases.
Published in:
Evidence-based Complementary & Alternative Medicine (eCAM), 2019, p. 1, doi. 10.1155/2019/3790728
By:
- Li, Xun;
- Chu, Shifeng;
- Liu, Yinjiao;
- Chen, Naihong
Publication type:
Article
Metabolism of IMM-H004 and Its Pharmacokinetic-Pharmacodynamic Analysis in Cerebral Ischemia/Reperfusion Injured Rats.
Published in:
Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00631
By:
- Zhang, Ziqian;
- Liu, Dandan;
- Jiang, Jianwei;
- Song, Xiuyun;
- Zou, Xiaowen;
- Chu, Shifeng;
- Xie, Kebo;
- Dai, Jungui;
- Chen, Naihong;
- Sheng, Li;
- Li, Yan
Publication type:
Article
The Active Glucuronide Metabolite of the Brain Protectant IMM-H004 with Poor Blood–Brain Barrier Permeability Demonstrates a High Partition in the Rat Brain via Multiple Mechanisms.
Published in:
Pharmaceutics, 2024, v. 16, n. 3, p. 330, doi. 10.3390/pharmaceutics16030330
By:
- Jiang, Jianwei;
- Luo, Lijun;
- Zhang, Ziqian;
- Liu, Xiao;
- Chen, Naihong;
- Li, Yan;
- Sheng, Li
Publication type:
Article
Chemokine-like factor 1 (CKLF1) is expressed in myocardial ischemia injury in vivo and in vitro.
Published in:
Biocell, 2024, v. 48, n. 6, p. 981, doi. 10.32604/biocell.2024.050011
By:
- JULING FENG;
- HAODONG CHEN;
- YANGBO LIU;
- QIDI AI;
- YANTAO YANG;
- LEI ZHAO;
- SHIFENG CHU;
- NAIHONG CHEN
Publication type:
Article
New Therapeutic Approaches to and Mechanisms of Ginsenoside Rg1 against Neurological Diseases.
Published in:
Cells (2073-4409), 2022, v. 11, n. 16, p. 2529, doi. 10.3390/cells11162529
By:
- Sun, Yang;
- Yang, Yantao;
- Liu, Shasha;
- Yang, Songwei;
- Chen, Chen;
- Lin, Meiyu;
- Zeng, Qi;
- Long, Junpeng;
- Yao, Jiao;
- Yi, Fan;
- Meng, Lei;
- Ai, Qidi;
- Chen, Naihong
Publication type:
Article
A Narrative Review of Cancer-Related Fatigue (CRF) and Its Possible Pathogenesis.
Published in:
Cells (2073-4409), 2019, v. 8, n. 7, p. 738, doi. 10.3390/cells8070738
By:
- Yang, Songwei;
- Chu, Shifeng;
- Gao, Yan;
- Ai, Qidi;
- Liu, Yingjiao;
- Li, Xun;
- Chen, Naihong
Publication type:
Article
IMM-H004 prevents toxicity induced by delayed treatment of t PA in a rat model of focal cerebral ischemia involving PKA-and PI3 K-dependent Akt activation.
Published in:
European Journal of Neuroscience, 2014, v. 39, n. 12, p. 2107, doi. 10.1111/ejn.12551
By:
- Zuo, Wei;
- Chen, Jiao;
- Zhang, Shuai;
- Tang, Jia;
- Liu, Hang;
- Zhang, Dongming;
- Chen, Naihong
Publication type:
Article
Virtual Screening against Phosphoglycerate Kinase 1 in Quest of Novel Apoptosis Inhibitors.
Published in:
Molecules, 2017, v. 22, n. 6, p. 1029, doi. 10.3390/molecules22061029
By:
- Jie Xia;
- Bo Feng;
- Qianhang Shao;
- Yuhe Yuan;
- Xiang Simon Wang;
- Naihong Chen;
- Song Wu
Publication type:
Article
Perspective and Therapeutic Potential of the Noncoding RNA–Connexin Axis.
Published in:
International Journal of Molecular Sciences, 2024, v. 25, n. 11, p. 6146, doi. 10.3390/ijms25116146
By:
- Li, Xinmu;
- Wang, Zhenzhen;
- Chen, Naihong
Publication type:
Article
Polygalasaponin F inhibits neuronal apoptosis induced by oxygen‐glucose deprivation and reoxygenation through the PI3K/Akt pathway.
Published in:
Basic & Clinical Pharmacology & Toxicology, 2020, v. 127, n. 3, p. 196, doi. 10.1111/bcpt.13408
By:
- Xie, Wei;
- Wulin, Hade;
- Shao, Guo;
- Wei, Liqin;
- Qi, Ruifang;
- Ma, Baohui;
- Chen, Naihong;
- Shi, Ruili
Publication type:
Article
Ginsenoside Rg1 Ameliorates Neuroinflammation via Suppression of Connexin43 Ubiquitination to Attenuate Depression.
Published in:
Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2021.709019
By:
- Huiqin Wang;
- Yantao Yang;
- Songwei Yang;
- Siyu Ren;
- Juling Feng;
- Yangbo Liu;
- Haodong Chen;
- Naihong Chen
Publication type:
Article

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