Works by Nagren, Kjell

Results: 96

Human dosimetry of carbon-11 labeled N-butan-2-yl-1-(2-chlorophenyl)-N-methylisoquinoline-3-carboxamide extrapolated from whole-body distribution kinetics and radiometabolism in rats.

Published in:

2010

By:

Luoto, Pauliina;
Laitinen, Iina;
Suilamo, Sami;
Någren, Kjell;
Roivainen, Anne;
Någren, Kjell

Publication type:

journal article

Insular dopamine D2 receptors and novelty seeking personality in Parkinson's disease.

Published in:

2004

By:

Kaasinen, Valtteri;
Aalto, Sargo;
Någren, Kjell;
Rinne, Juha O.;
Någren, Kjell

Publication type:

journal article

Prolonged Central μ-Opioid Receptor Occupancy after Single and Repeated Nalmefene Dosing.

Published in:

Neuropsychopharmacology, 2005, v. 30, n. 12, p. 2245, doi. 10.1038/sj.npp.1300790

By:

Ingman, Kimmo;
Hagelberg, Nora;
Aalto, Sargo;
Någren, Kjell;
Juhakoski, Auni;
Karhuvaara, Sakari;
Kallio, Antero;
Oikonen, Vesa;
Hietala, Jarmo;
Scheinin, Harry

Publication type:

Article

Effects of intravenous glucose on dopaminergic function in the human brain in vivo.

Published in:

Synapse, 2007, v. 61, n. 9, p. 748, doi. 10.1002/syn.20418

By:

Haltia, Lauri T.;
Rinne, Juha O.;
Merisaari, Harri;
Maguire, Ralph P.;
Savontaus, Eriika;
Helin, Semi;
Någren, Kjell;
Kaasinen, Valtteri

Publication type:

Article

μ-Receptor agonism with alfentanil increases striatal dopamine D2 receptor binding in man.

Published in:

Synapse, 2002, v. 45, n. 1, p. 25, doi. 10.1002/syn.10078

By:

Hagelberg, Nora;
Kajander, Jaana K.;
Någren, Kjell;
Hinkka, Susanna;
Hietala, Jarmo;
Scheinin, Harry

Publication type:

Article

PET examination of the monoamine transporter with [11c]β-CIT and [11c]β-CFT in early parkinson's disease.

Published in:

Synapse, 1995, v. 21, n. 2, p. 97, doi. 10.1002/syn.890210202

By:

Rinne, Juha O.;
Laihinen, Arto;
Någren, Kjell;
Ruottinen, Hanna;
Ruotsawnen, Ulla;
Rinne, Urpo K.

Publication type:

Article

Correlations between amyloid and metabolic pet imaging in cognitively normal adults with a family history of late-onset Alzheimer's disease

Published in:

2011

By:

Cummings, Megan;
Rinne, Juha;
Mosconi, Lisa;
Tsui, Wai;
Murray, John;
Li, Yi;
Glodzik, Lidia;
McHugh, Pauline;
Williams, Schantel;
Goldsmith, Stanley;
Vallabhajosula, Shankar;
Scheinin, Noora;
Viljanen, Tapio;
Nagren, Kjell;
De Leon, Mony

Publication type:

Abstract

P2-093: The effects of the E4 allele of apolipoprotein E and the K variant of butyrylcholinesterase on cerebral butyrylcholinesterase activity in patients with Alzheimer's disease

Published in:

2008

By:

Virta, Jere R.;
Någren, Kjell;
Jarvenpaa, Tarja;
Roivainen, Anne;
Oikonen, Vesa;
Mononen, Nina;
Mattila, Kari M.;
Lehtimaki, Terho;
Kurki, Timo;
Rinne, Juha O.

Publication type:

Abstract

P2-073: Reproducibility of automated ROI analysis of PET amyloid ligand [11C]PIB uptake

Published in:

2008

By:

Scheinin, Noora M.;
Aalto, Sargo;
Wilson, Ian A.;
Kemppainen, Nina;
Någren, Kjell;
Kailajärvi, Marita;
Scheinin, Mika;
Rinne, Juha O.

Publication type:

Abstract

P2-033: Pet amyloid ligand [11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease

Published in:

2008

By:

Koivunen, Jaana;
Verkkoniemi, Auli;
Aalto, Sargo;
Paetau, Anders;
Ahonen, Jukka-Pekka;
Viitanen, Matti;
Nagren, Kjell;
Kalimo, Hannu;
Rinne, Juha

Publication type:

Abstract

IC-P2-133: Reproducibility of automated ROI analysis of PET amyloid ligand [11C]PIB uptake

Published in:

2008

By:

Scheinin, Noora M.;
Aalto, Sargo;
Wilson, Ian;
Kemppainen, Nina;
Någren, Kjell;
Kailajärvi, Marita;
Scheinin, Mika;
Rinne, Juha O.

Publication type:

Abstract

Metabolic Imaging of Ovarian Tumors with Carbon-11-Methionine: A PET Study.

Published in:

Journal of Nuclear Medicine, 1995, v. 36, n. 12, p. 2196

By:

Lapela, Maria;
Leskinen-Kallio, Sirkku;
Varpula, Matti;
Grénman, Seija;
Salmi, Tuula;
Alanen, Kalle;
Någren, Kjell;
Lehikoinen, Pertti;
Ruotsalainen, Ulla;
Teräs, Mika;
Joensuu, Heikki

Publication type:

Article

Carbon-11-Methionine PET Imaging of Malignant Melanoma.

Published in:

Journal of Nuclear Medicine, 1995, v. 36, n. 10, p. 1806

By:

Lindholm, Paula;
Leskinen, Sirkku;
Någren, Kjell;
Lehikoinen, Pertti;
Ruotsalainen, Ulla;
Teräs, Mika;
Joensuu, Heikki

Publication type:

Article

PET Studies on Brain Monoamine Transporters with Carbon-11-β-CIT in Parkinson's Disease.

Published in:

Journal of Nuclear Medicine, 1995, v. 36, n. 7, p. 1263

By:

Laihinen, Arto O.;
Rinne, Juha O.;
Någren, Kjell Å.;
Lehikoinen, Pertti K.;
Oikonen, Vesa J.;
Ruotsalainen, Ulla H.;
Ruottinen, Hanna M.;
Rinne, Urpo K.

Publication type:

Article

PET Studies on Dopamine D1 Receptors in the Human Brain with Carbon-11-SCH 39166 and Carbon-11-NNC 756.

Published in:

Journal of Nuclear Medicine, 1994, v. 35, n. 12, p. 1916

By:

Laihinen, Arto O.;
Rinne, Juha O.;
Ruottinen, Hanna M.;
Någren, Kjell Å.;
Lehikoinen, Pertti K.;
Oikonen, Vesa J.;
Ruotsalainen, Ulla H.;
Rinne, Urpo K.

Publication type:

Article

Imaging of Uterine Carcinoma by Carbon-11-Methionine and PET.

Published in:

Journal of Nuclear Medicine, 1994, v. 35, n. 10, p. 1618

By:

Lapela, Maria;
Leskinen-Kallio, Sirkku;
Varpula, Matti;
Grenman, Seija;
Alanen, Kalle;
Någren, Kjell;
Lehikoinen, Pertti;
Ruotsalainen, Ulla;
Teräs, Mika;
Joensuu, Heikki

Publication type:

Article

Comparison of Fluorine-18-Fluorodeoxyglucose and Carbon-11-Methionine in Head and Neck Cancer.

Published in:

Journal of Nuclear Medicine, 1993, v. 34, n. 10, p. 1711

By:

Lindholm, Paula;
Leskinen-Kalilo, Sirkku;
Minn, Heikki;
Bergman, Jorgen;
Haaparanta, Merja;
Lehikoinen, Perth;
NAgren, Kjell;
Ruotsalainen, Ulla;
Terä, Mika;
Joensuu, Heikki

Publication type:

Article

Uptake of Carbon-11-Methionine and Fluorodeoxyglucose in Non-Hodgkin's Lymphoma: A PET Study.

Published in:

Journal of Nuclear Medicine, 1991, v. 32, n. 6, p. 1211

By:

Leskinen-Kallio, Sirkku;
Ruotsalainen, Ulla;
Någren, Kjell;
Teräs, Mika;
Joensuu, Heikki

Publication type:

Article

Synthesis of L- and D-[Methyl-11C] Methionine.

Published in:

Journal of Nuclear Medicine, 1987, v. 28, n. 6, p. 1037

By:

Långström, Bengt;
Antoni, Gunnar;
Gullberg, Per;
Halldin, Christer;
Malmborg, Fetter;
Någren, Kjell;
Rimland, Annika;
Svärd, Hans

Publication type:

Article

Substantial Thalamostriatal Dopaminergic Defect in Unverricht-Lundborg Disease.

Published in:

Epilepsia (Series 4), 2007, v. 48, n. 9, p. 1768, doi. 10.1111/j.1528-1167.2007.01118.x

By:

Korja, Miikka;
Kaasinen, Valtteri;
Lamusuo, Salla;
Parkkola, Riitta;
Någren, Kjell;
Marttila, Reijo J.

Publication type:

Article

A PET Study on the Acute Effect of Ethanol on Striatal D2 Dopamine Receptors with [[sup 11] C]Raclopride in Healthy Males.

Published in:

Human Psychopharmacology: Clinical & Experimental, 1997, v. 12, n. 2, p. 145, doi. 10.1002/(SICI)1099-1077(199703/04)12:2<145::AID-HUP851>3.0.CO;2-L

By:

Salonen, Iiris;
Hietala, Jarmo;
Laihinen, Arto;
Lehikoinen, Pertti;
Leino, Lasse;
Någren, Kjell;
Ruotsalainen, Ulla;
Oikonen, Vesa;
Tuokkola, Terhi;
Näntö, Veikko

Publication type:

Article

Frontal and Temporal Dopamine Release during Working Memory and Attention Tasks in Healthy Humans: a Positron Emission Tomography Study Using the High-Affinity Dopamine D2 Receptor Ligand [11C]FLB 457.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 10, p. 2471, doi. 10.1523/JNEUROSCI.2097-04.2005

By:

Aalto, Sargo;
Brück, Anna;
Laine, Matti;
Någren, Kjell;
Rinne, Juha O.

Publication type:

Article

Cognitive reserve hypothesis: Pittsburgh Compound B and fluorodeoxyglucose positron emission tomography in relation to education in mild Alzheimer's disease.

Published in:

Annals of Neurology, 2008, v. 63, n. 1, p. 112, doi. 10.1002/ana.21212

By:

Kemppainen, Nina M.;
Aalto, Sargo;
Karrasch, Mira;
Någren, Kjell;
Savisto, Nina;
Oikonen, Vesa;
Viitanen, Matti;
Parkkola, Riitta;
Rinne, Juha O.

Publication type:

Article

Decreased binding of [11C]flumazenil in Angelman syndrome patients with GABA(A) receptor beta3 subunit deletions.

Published in:

2001

By:

Holopainen, Irma E.;
Metsähonkala, E.-Liisa;
Kokkonen, Hannaleena;
Parkkola, Riitta K.;
Manner, Tuula E.;
Någren, Kjell;
Korpi, Esa R.;
Holopainen, I E;
Metsähonkala, E L;
Kokkonen, H;
Parkkola, R K;
Manner, T E;
Någren, K;
Korpi, E R

Publication type:

journal article

Striatal dopamine D2/D3 receptor availability correlates with individual response characteristics to pain.

Published in:

European Journal of Neuroscience, 2004, v. 20, n. 6, p. 1587, doi. 10.1111/j.1460-9568.2004.03622.x

By:

Pertovaara, Antti;
Martikainen, Ilkka K.;
Hagelberg, Nora;
Mansikka, Heikki;
Någren, Kjell;
Hietala, Jarmo;
Scheinin, Harry

Publication type:

Article

Expectation of caffeine induces dopaminergic responses in humans.

Published in:

European Journal of Neuroscience, 2004, v. 19, n. 8, p. 2352, doi. 10.1111/j.1460-9568.2004.03310.x

By:

Kaasinen, Valtteri;
Aalto, Sargo;
Någren, Kjell;
Rinne, Juha O.

Publication type:

Article

Measurement of Cortical Dopamine D1 Receptor Binding With [11C]SCH 23390: A Test-Retest Analysis.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2001, v. 21, n. 10, p. 1146, doi. 10.1097/00004647-200110000-00002

By:

Hirvonen, Jussi;
Någren, Kjell;
Kajander, Jaana;
Hietala, Jarmo

Publication type:

Article

Measurement of Striatal D2 Dopamine Receptor Density and Affinity with [11C]-Raclopride in Vivo: A Test-Retest Analysis.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 1999, v. 19, n. 2, p. 210, doi. 10.1097/00004647-199902000-00012

By:

Hietala, Jarmo;
Någren, Kjell;
Lehikoinen, Pertti;
Ruotsalainen, Ulla;
Syvälahti, Erkka

Publication type:

Article

Decrease in Human Striatal Dopamine D2 Receptor Density with Age: A PET Study with [11C]Raclopride.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 1993, v. 13, n. 2, p. 310, doi. 10.1038/jcbfm.1993.39

By:

Rinne, Juha O.;
Hietala, Jarmo;
Ruotsalainen, Ulla;
Säkö, Erkki;
Laihinen, Arto;
Någren, Kjell;
Lehikoinen, Pertti;
Oikonen, Vesa;
Syvälahti, Erkka

Publication type:

Article

COMT Val158Met genotype does not alter cortical or striatal dopamine D2 receptor availability in vivo.

Published in:

2010

By:

Hirvonen, Mika M;
Någren, Kjell;
Rinne, Juha O;
Pesonen, Ullamari;
Vahlberg, Tero;
Hagelberg, Nora;
Hietala, Jarmo

Publication type:

journal article

Effects of fluoxetine on dopamine D2 receptors in the human brain: a positron emission tomography study with [11C]raclopride.

Published in:

International Journal of Neuropsychopharmacology, 2004, v. 7, n. 4, p. 431, doi. 10.1017/s146114570400450x

By:

Jani Penttilä;
Jaana Kajander;
Sargo Aalto;
Jussi Hirvonen;
Kjell Någren;
Tuula Ilonen;
Erkka Syvälahti

Publication type:

Article

Effects of lorazepam administration on striatal dopamine D[sub 2] receptor binding characteristics in man - a positron emission tomography study.

Published in:

Psychopharmacology, 1997, v. 132, n. 4, p. 361, doi. 10.1007/s002130050356

By:

Hietala, J.;
Kuoppamäki, Mikko;
Någren, Kjell;
Lehikoinen, Pertti;
Syvälahti, Erkka

Publication type:

Article

Myocardial efficiency during levosimendan infusion in congestive heart failure*.

Published in:

Clinical Pharmacology & Therapeutics, 2000, v. 68, n. 5, p. 522, doi. 10.1067/mcp.2000.110972

By:

Ukkonen, Heikki;
Saraste, Markku;
Akkila, Juha;
Knuuti, Juhani;
Karanko, Meri;
Iida, Hidehiro;
Lehikoinen, Pertti;
Någren, Kjell;
Lehtonen, Lasse;
Voipio-Pulkki, Liisa-Maria

Publication type:

Article

Myocardial efficiency during calcium sensitization with levosimendan: A noninvasive study with positron emission tomography and echocardiography in healthy volunteers*.

Published in:

Clinical Pharmacology & Therapeutics, 1997, v. 61, n. 5, p. 596, doi. 10.1016/S0009-9236(97)90139-9

By:

Ukkonen, Heikki;
Saraste, Markku;
Akkila, Juha;
Knuuti, M. Juhani;
Lehikoinen, Pertti;
Någren, Kjell;
Lehtonen, Lasse;
Voipio-Pulkki, Liisa-Maria

Publication type:

Article

A PET Tracer for Brain α2C Adrenoceptors, 11C-ORM-13070: Radiosynthesis and Preclinical Evaluation in Rats and Knockout Mice.

Published in:

Journal of Nuclear Medicine, 2014, v. 55, n. 7, p. 1171, doi. 10.2967/jnumed.113.135574

By:

Arponen, Eveliina;
Helin, Semi;
Marjamaki, Paivi;
Gronroos, Tove;
Holm, Patrik;
Loyttyniemi, Eliisa;
Nagren, Kjell;
Scheinin, Mika;
Haaparanta-Solin, Merja;
Sallinen, Jukka;
Solin, Olof

Publication type:

Article

Assessment of Islet Specificity of Dihydrotetrabenazine Radiotracer Binding in Rat Pancreas and Human Pancreas.

Published in:

Journal of Nuclear Medicine, 2010, v. 51, n. 9, p. 1439, doi. 10.2967/jnumed.109.074492

By:

Fagerholm, Veronica;
Mikkola, Kirsi K.;
Ishizu, Tamiko;
Arponen, Eveliina;
Kauhanen, Saila;
Någren, Kjell;
Solin, Olof;
Nuutila, Pirjo;
Haaparanta, Merja

Publication type:

Article

Uptake of 11C-Choline in Mouse Atherosclerotic Plaques.

Published in:

Journal of Nuclear Medicine, 2010, v. 51, n. 5, p. 798, doi. 10.2967/jnumed.109.071704

By:

Laitinen, Iina E. K.;
Luoto, Pauliina;
Någren, Kjell;
Marjamäki, Paivi M.;
Silvola, Johanna M. U.;
Hellberg, Sanna;
Laine, V. Jukka O.;
Ylä-Herttuala, Seppo;
Knuuti, Juhani;
Roivainen, Anne

Publication type:

Article

1-11C-Methyl-4-Piperidinyl-N-Butyrate Radiation Dosimetry in Humans by Dynamic Organ-Specific Evaluation.

Published in:

Journal of Nuclear Medicine, 2008, v. 49, n. 3, p. 347, doi. 10.2967/jnumed.107.047233

By:

Virta, Jere R.;
Tolvanen, Tuula;
Någren, Kjell;
Brück, Anna;
Roivainen, Anne;
Rinne, Juha O.

Publication type:

Article

Biodistribution and Radiation Dosimetry of the Amyloid Imaging Agent 11C-PIB in Humans.

Published in:

Journal of Nuclear Medicine, 2007, v. 48, n. 1, p. 128

By:

Scheinin, Noora M.;
Tolvanen, Tuula K.;
Wilson, Ian A.;
Arponen, Eveliina M.;
Någren, Kjell Å.;
Rinne, Juha O.

Publication type:

Article

Biodistribution and Blood Metabolism of 1-11C-Methyl-4-Piperidinyl n-Butyrate in Humans: An Imaging Agent for In Vivo Assessment of Butyrylcholinesterase Activity with PET.

Published in:

Journal of Nuclear Medicine, 2004, v. 45, n. 12, p. 2032

By:

Roivainen, Anne;
Rinne, Juha;
Virta, Jere;
Järvenpää, Tarja;
Salomäki, Satu;
Miexiang Yu;
Någren, Kjell

Publication type:

Article

Imaging of Adrenal Incidentalomas with PET Using 11C-Metomidate and 18F-FDG.

Published in:

Journal of Nuclear Medicine, 2004, v. 45, n. 6, p. 972

By:

Minn, Heikki;
Salonen, Anna;
Friberg, Johan;
Roivainen, Anne;
Viljanen, Tapio;
Långsjö, Jaakko;
Salmi, Jorma;
Välimäki, Matti;
Någren, Kjell;
Nuutila, Pirjo

Publication type:

Article

Exercise Training in Chronic Heart Failure: Beneficial Effects on Cardiac 11C-Hydroxyephedrine PET, Autonomic Nervous Control, and Ventricular Repolarization.

Published in:

Journal of Nuclear Medicine, 2002, v. 43, n. 6, p. 773

By:

Pietilä, Mikko;
Malminiemi, Kimmo;
Vesalainen, Risto;
Jartti, Tuomas;
Teräs, Mika;
Någren, Kjell;
Lehikoinen, Pertti;
Voipio-Pulkki, Liisa-Maria

Publication type:

Article

Upregulation of Putaminal Dopamine D2 Receptors in Early Parkinson's Disease: A Comparative PET Study with [11C]Raclopride and [11C]N-Methylspiperone.

Published in:

Journal of Nuclear Medicine, 2000, v. 41, n. 1, p. 65

By:

Kaasinen, Valtteri;
Ruottinen, Hanna M.;
Någren, Kjell;
Lehikoinen, Pertti;
Oikonen, Vesa;
Rinne, Juha .

Publication type:

Article

Improved syntheses of the PET radioligands, [11C]FLB 457, [11C]MDL 100907 and [11C]β-CIT-FE, by the use of [11C]methyl triflate.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 1998, v. 41, n. 6, p. 545, doi. 10.1002/(SICI)1099-1344(199806)41:6<545::AID-JLCR99>3.0.CO;2-7

By:

Lundkvist, Camilla;
Sandell, Johan;
Någren, Kjell;
Pike, Victor W.;
Halldin, Christer

Publication type:

Article

Preparation of 4- and 6-[76Br] bromometaraminol, two potential radiotracers for the study of the myocardial norepinephrine neuronal reuptake system with PET.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 1997, v. 39, n. 10, p. 803, doi. 10.1002/(SICI)1099-1344(199710)39:10<803::AID-JLCR27>3.0.CO;2-R

By:

Langer, Oliver;
Dollé, Frédéric;
Loc'h, Christian;
Halldin, Christer;
Vaufrey, Françoise;
Coulon, Christine;
Crouzel, Christian;
Någren, Kjell;
Mazière, Bernard

Publication type:

Article

Preparation of the antioestrogenic compound N-[methyl-11C]-toremifene for the study of oestrogen-receptor positive tumors in vivo.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 1991, v. 29, n. 9, p. 1085, doi. 10.1002/jlcr.2580290915

By:

Någren, Kjell;
Takahashi, Toshihiro;
Lehikoinen, Pertti;
Bergman, Jörgen

Publication type:

Article

Synthesis of three 11C-labelled methionine-containing enkephal in analogues.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 1988, v. 25, n. 2, p. 149, doi. 10.1002/jlcr.2580250206

By:

Någren, Kjell;
Ragnarsson, Ulf;
Långström, Bengt

Publication type:

Article

Synthesis of D/L- and L-SE-[methyl-11C]selenomethionine.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 1988, v. 25, n. 2, p. 133, doi. 10.1002/jlcr.2580250204

By:

Någren, Kjell;
Långström, Bengt

Publication type:

Article

Cognitive Decline and Amyloid Accumulation in Patients with Mild Cognitive Impairment.

Published in:

Dementia & Geriatric Cognitive Disorders, 2012, v. 34, n. 1, p. 31, doi. 10.1159/000341580

By:

Koivunen, Jaana;
Karrasch, Mira;
Scheinin, Noora M.;
Aalto, Sargo;
Vahlberg, Tero;
Någren, Kjell;
Helin, Semi;
Viitanen, Matti;
Rinne, Juha O.

Publication type:

Article

Myocardial blood flow and adenosine A2A receptor density in endurance athletes and untrained men.

Published in:

Journal of Physiology, 2008, v. 586, n. 21, p. 5193, doi. 10.1113/jphysiol.2008.158113

By:

Heinonen, Ilkka;
Nesterov, Sergey V.;
Liukko, Kaisa;
Kemppainen, Jukka;
Någren, Kjell;
Luotolahti, Matti;
Virsu, Pauliina;
Oikonen, Vesa;
Nuutila, Pirjo;
Kujala, Urho M.;
Kainulainen, Heikki;
Boushel, Robert;
Knuuti, Juhani;
Kalliokoski, Kari K.

Publication type:

Article