Works by Nagaraj, Ram H.

Results: 39

Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease.

Published in:

Redox Report, 2010, v. 15, n. 4, p. 161, doi. 10.1179/174329210X12650506623645

By:

Bonda, David J.;
Mailankot, Maneesh;
Stone, Jeremy G.;
Garrett, Matthew R.;
Staniszewska, Magdalena;
Castellani, Rudy J.;
Siedlak, Sandra L.;
Xiongwei Zhu;
Hyoung-gon Lee;
Perry, George;
Nagaraj, Ram H.;
Smith, Mark A.

Publication type:

Article

Mechanisms contributing to inhibition of retinal ganglion cell death by cell permeable peptain-1 under glaucomatous stress.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-02070-8

By:

Johnson, Gretchen A.;
Kodati, Bindu;
Nahomi, Rooban B.;
Pham, Jennifer H.;
Krishnamoorthy, Vignesh R.;
Phillips, Nicole R.;
Krishnamoorthy, Raghu R.;
Nagaraj, Ram H.;
Stankowska, Dorota L.

Publication type:

Article

Lens capsule advanced glycation end products induce senescence in epithelial cells: Implications for secondary cataracts.

Published in:

Aging Cell, 2024, v. 23, n. 10, p. 1, doi. 10.1111/acel.14249

By:

Cooksley, Grace;
Nam, Mi‐Hyun;
Nahomi, Rooban B.;
Rankenberg, Johanna;
Smith, Andrew J. O.;
Wormstone, Yvette M.;
Wormstone, I. Michael;
Nagaraj, Ram H.

Publication type:

Article

Aggrelyte‐2 promotes protein solubility and decreases lens stiffness through lysine acetylation and disulfide reduction: Implications for treating presbyopia.

Published in:

Aging Cell, 2023, v. 22, n. 4, p. 1, doi. 10.1111/acel.13797

By:

Panja, Sudipta;
Nahomi, Rooban B.;
Rankenberg, Johanna;
Michel, Cole R.;
Gaikwad, Hanmant;
Nam, Mi‐Hyun;
Nagaraj, Ram H.

Publication type:

Article

AGEs in human lens capsule promote the TGFβ2-mediated EMT of lens epithelial cells: implications for age-associated fibrosis.

Published in:

Aging Cell, 2016, v. 15, n. 3, p. 465, doi. 10.1111/acel.12450

By:

Raghavan, Cibin T.;
Smuda, Mareen;
Smith, Andrew J. O.;
Howell, Scott;
Smith, Dawn G.;
Singh, Annapurna;
Gupta, Pankaj;
Glomb, Marcus A.;
Wormstone, Ian Michael;
Nagaraj, Ram H.

Publication type:

Article

Correction: Systemically administered peptain-1 inhibits retinal ganglion cell death in animal models: implications for neuroprotection in glaucoma.

Published in:

2019

By:

Stankowska, Dorota L.;
Nam, Mi-Hyun;
Nahomi, Rooban B.;
Chaphalkar, Renuka M.;
Nandi, Sandip K.;
Fudala, Rafal;
Krishnamoorthy, Raghu R.;
Nagaraj, Ram H.

Publication type:

Correction Notice

Systemically administered peptain-1 inhibits retinal ganglion cell death in animal models: implications for neuroprotection in glaucoma.

Published in:

Cell Death Discovery, 2019, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41420-019-0194-2

By:

Stankowska, Dorota L.;
Nam, Mi-Hyun;
Nahomi, Rooban B.;
Chaphalkar, Renuka M.;
Nandi, Sandip K.;
Fudala, Rafal;
Krishnamoorthy, Raghu R.;
Nagaraj, Ram H.

Publication type:

Article

Peptains block retinal ganglion cell death in animal models of ocular hypertension: implications for neuroprotection in glaucoma.

Published in:

Cell Death & Disease, 2022, v. 13, n. 11, p. 1, doi. 10.1038/s41419-022-05407-2

By:

Nam, Mi-Hyun;
Stankowska, Dorota L.;
Johnson, Gretchen A.;
Nahomi, Rooban B.;
Pantcheva, Mina B.;
Nagaraj, Ram H.

Publication type:

Article

UVA Light-mediated Ascorbate Oxidation in Human Lenses.

Published in:

Photochemistry & Photobiology, 2017, v. 93, n. 4, p. 1091, doi. 10.1111/php.12717

By:

Rakete, Stefan;
Nagaraj, Ram H.

Publication type:

Article

Time-resolved and Steady-state Fluorescence Spectroscopic Studies of the Human Lens with Comparison to Argpyrimidine, Pentosidine and 3-OH-kynurenine.

Published in:

Photochemistry & Photobiology, 2002, v. 76, n. 5, p. 549, doi. 10.1562/0031-8655(2002)0760549TRASSF2.0.CO2

By:

Kessel, Line;
Kalinin, Stanislav;
Nagaraj, Ram H.;
Larsen, Michael;
Johansson, Lennart B.-Å.

Publication type:

Article

Developmental aspects of galectin-3 expression in the lens.

Published in:

Histochemistry & Cell Biology, 2003, v. 119, n. 3, p. 219, doi. 10.1007/s00418-003-0508-5

By:

Dahm, Ralf;
Bramke, Silvia;
Dawczynski, Jens;
Nagaraj, Ram H.;
Kasper, Michael

Publication type:

Article

Transforming growth factor-ß2-mediated mesenchymal transition in lens epithelial cells is repressed in the absence of RAGE.

Published in:

Biochemical Journal, 2021, v. 478, n. 12, p. 2285, doi. 10.1042/BCJ20210069

By:

Mi-Hyun Nam;
Pantcheva, Mina B.;
Rankenberg, Johanna;
Nagaraj, Ram H.

Publication type:

Article

Aspirin inhibits TGFβacetylation of K56 and K122 in histone H3.

Published in:

Biochemical Journal, 2020, v. 477, n. 1, p. 75, doi. 10.1042/BCJ20190540

By:

Mi-Hyun Nam;
Smith, Andrew J. O.;
Pantcheva, Mina B.;
Ko Uoon Park;
Brzezinski IV, Joseph A.;
Galligan, James J.;
Fritz, Kristofer;
Wormstone, I. Michael;
Nagaraj, Ram H.

Publication type:

Article

Matrix-bound AGEs enhance TGFβ2-mediated mesenchymal transition of lens epithelial cells via the noncanonical pathway: implications for secondary cataract formation.

Published in:

Biochemical Journal, 2018, v. 475, n. 8, p. 1427, doi. 10.1042/BCJ20170856

By:

Mi-Hyun Nam;
Nagaraj, Ram H.

Publication type:

Article

αB-crystallin is essential for the TGF-β2-mediated epithelial to mesenchymal transition of lens epithelial cells.

Published in:

Biochemical Journal, 2016, v. 473, n. 10, p. 1455, doi. 10.1042/BCJ20160128

By:

Nahomi, Rooban B.;
Pantcheva, Mina B.;
Nagaraj, Ram H.

Publication type:

Article

Identification of peptides in human Hsp20 and Hsp27 that possess molecular chaperone and anti-apoptotic activities.

Published in:

Biochemical Journal, 2015, v. 465, n. 1, p. 115, doi. 10.1042/BJ20140837

By:

Nahomi, Rooban B.;
DiMauro, Michael A.;
Wang, Benlian;
Nagaraj, Ram H.

Publication type:

Article

The role of HIF‐1α in the TGF‐β2‐mediated epithelial‐to‐mesenchymal transition of human lens epithelial cells.

Published in:

Journal of Cellular Biochemistry, 2018, v. 119, n. 8, p. 6814, doi. 10.1002/jcb.26877

By:

Nahomi, Rooban B.;
Nagaraj, Ram H.

Publication type:

Article

The role of HIF‐1α in the TGF‐β2‐mediated epithelial‐to‐mesenchymal transition of human lens epithelial cells.

Published in:

Journal of Cellular Biochemistry, 2018, v. 119, n. 8, p. 6814, doi. 10.1002/jcb.26877

By:

Nahomi, Rooban B.;
Nagaraj, Ram H.

Publication type:

Article

Pyridoxamine Inhibits Maillard Reactions in Diabetic Rat Lenses.

Published in:

Ophthalmic Research, 2006, v. 38, n. 5, p. 294, doi. 10.1159/000095773

By:

Padival, Simi;
Nagaraj, Ram H.

Publication type:

Article

Immunolocalization and quantification of advanced glycation end products in retinal neovascular membranes and serum: A possible role in ocular neovascularization.

Published in:

Current Eye Research, 2002, v. 25, n. 3, p. 139, doi. 10.1076/ceyr.25.3.139.13480

By:

Swamy-Mruthinti, S.;
Miriam, K. Coral;
Kumar, S. Krishna;
Biswas, Jyotirmay;
Ramakrishnan, S.;
Nagaraj, Ram H.;
Sulochana, K.N.

Publication type:

Article

High concentrations of glucose induce synthesis of argpyrimidine in retinalendothelial cells.

Published in:

Current Eye Research, 2001, v. 23, n. 2, p. 106, doi. 10.1076/ceyr.23.2.106.5472

By:

Padayatti, Pius S.;
Jiang, Chunling;
Glomb, Marcus A.;
Uchida, Koji;
Nagaraj, Ram H.

Publication type:

Article

Chemical Modulation of the Chaperone Function of Human αA-Crystallin.

Published in:

Journal of Biochemistry, 2008, v. 144, n. 1, p. 21, doi. 10.1093/jb/mvn037

By:

Biswas, Ashis;
Lewis, Shawn;
Benlian Wang;
Miyagi, Masaru;
Santoshkumar, Puttur;
Gangadhariah, Mahesha H.;
Nagaraj, Ram H.

Publication type:

Article

Promotion of Protein Solubility and Reduction in Stiffness in Human Lenses by Aggrelyte-1: Implications for Reversing Presbyopia.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2196, doi. 10.3390/ijms24032196

By:

Panja, Sudipta;
Gaikwad, Hanmant;
Rankenberg, Johanna;
Nam, Mi-Hyun;
Nagaraj, Ram H.

Publication type:

Article

Kynurenic Acid Protects Against Ischemia/Reperfusion-Induced Retinal Ganglion Cell Death in Mice.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 5, p. 1795, doi. 10.3390/ijms21051795

By:

Nahomi, Rooban B.;
Nam, Mi-Hyun;
Rankenberg, Johanna;
Rakete, Stefan;
Houck, Julie A.;
Johnson, Ginger C.;
Stankowska, Dorota L.;
Pantcheva, Mina B.;
MacLean, Paul S.;
Nagaraj, Ram H.

Publication type:

Article

The Other Side of the Maillard Reaction.

Published in:

Annals of the New York Academy of Sciences, 2008, v. 1126, p. 107, doi. 10.1196/annals.1433.045

By:

Nagaraj, Ram H.;
Biswas, Ashis;
Miller, Antonia;
Oya‐Ito, Tomoko;
Bhat, Manjunatha

Publication type:

Article

Dicarbonyl Stress and Apoptosis of Vascular Cells: Prevention by αB-Crystallin.

Published in:

Annals of the New York Academy of Sciences, 2005, v. 1043, n. 1, p. 158, doi. 10.1196/annals.1333.020

By:

NAGARAJ, RAM H.;
OYA‐ITO, TOMOKO;
BHAT, MANJUNATHA;
LIU, BINGFEN

Publication type:

Article

Effects of photobleaching on selected advanced glycation end products in the human lens.

Published in:

BMC Research Notes, 2015, v. 8, n. 1, p. 223, doi. 10.1186/s13104-015-0977-3

By:

Holm, Thomas;
Raghavan, Cibin T.;
Nahomi, Rooban;
Nagaraj, Ram H.;
Kessel, Line

Publication type:

Article

The role of the cysteine residue in the chaperone and anti-apoptotic functions of human Hsp27.

Published in:

Journal of Cellular Biochemistry, 2010, v. 110, n. 2, p. 408, doi. 10.1002/jcb.22552

By:

Pasupuleti, NagaRekha;
Gangadhariah, Mahesha;
Padmanabha, Smitha;
Santhoshkumar, Puttur;
Nagaraj, Ram H.

Publication type:

Article

Effect of methylglyoxal modification and phosphorylation on the chaperone and anti‐apoptotic properties of heat shock protein 27.

Published in:

Journal of Cellular Biochemistry, 2006, v. 99, n. 1, p. 279, doi. 10.1002/jcb.20781

By:

Tomoko Oya‐Ito;
Bing‐Fen Liu;
Ram H. Nagaraj

Publication type:

Article

Hydroimidazolone Modification of the Conserved Arg12 in Small Heat Shock Proteins: Studies on the Structure and Chaperone Function Using Mutant Mimics.

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0030257

By:

Nagaraj, Ram H.;
Panda, Alok Kumar;
Shanthakumar, Shilpa;
Santhoshkumar, Puttur;
Pasupuleti, NagaRekha;
Wang, Benlian;
Biswas, Ashis

Publication type:

Article

Peptain-1 blocks ischemia/reperfusion-induced retinal capillary degeneration in mice.

Published in:

Frontiers in Cellular Neuroscience, 2024, p. 1, doi. 10.3389/fncel.2024.1441924

By:

Mi-Hyun Nam;
Dhillon, Armaan;
Nahomi, Rooban B.;
Carrillo, Noelle L.;
Hougen, Clarinda S.;
Nagaraj, Ram H.

Publication type:

Article

Glycation-mediated protein crosslinking and stiffening in mouse lenses are inhibited by carboxitin in vitro.

Published in:

Glycoconjugate Journal, 2021, v. 38, n. 3, p. 347, doi. 10.1007/s10719-020-09961-9

By:

Nandi, Sandip K.;
Rankenberg, Johanna;
Rakete, Stefan;
Nahomi, Rooban B.;
Glomb, Marcus A.;
Linetsky, Mikhail D.;
Nagaraj, Ram H.

Publication type:

Article

Advanced Glycation End Products Upregulate CD40 in Human Retinal Endothelial and Müller Cells: Relevance to Diabetic Retinopathy.

Published in:

Cells (2073-4409), 2024, v. 13, n. 5, p. 429, doi. 10.3390/cells13050429

By:

Portillo, Jose-Andres C.;
Pfaff, Amelia;
Vos, Sarah;
Weng, Matthew;
Nagaraj, Ram H.;
Subauste, Carlos S.

Publication type:

Article

Quantifying Protein Acetylation in Diabetic Nephropathy from Formalin‐Fixed Paraffin‐Embedded Tissue.

Published in:

Proteomics - Clinical Applications, 2024, v. 18, n. 6, p. 1, doi. 10.1002/prca.202400018

By:

Schwab, Stefanie K.;
Harris, Peter S.;
Michel, Cole;
McGinnis, Courtney D.;
Nahomi, Rooban B.;
Assiri, Mohammed A.;
Reisdorph, Richard;
Henriksen, Kammi;
Orlicky, David J.;
Levi, Moshe;
Rosenberg, Avi;
Nagaraj, Ram H.;
Fritz, Kristofer S.

Publication type:

Article

Methylglyoxal modifies heat shock protein 27 in glomerular mesangial cells

Published in:

FEBS Letters, 2003, v. 551, n. 1-3, p. 113, doi. 10.1016/S0014-5793(03)00874-3

By:

Padival, Anoop K.;
Crabb, John W.;
Nagaraj, Ram H.

Publication type:

Article

A Neuroprotective Peptide Modulates Retinal cAMP Response Element-Binding Protein (CREB), Synapsin I (SYN1), and Growth-Associated Protein 43 (GAP43) in Rats with Silicone Oil-Induced Ocular Hypertension.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 2, p. 219, doi. 10.3390/biom15020219

By:

Johnson, Gretchen A.;
Krishnamoorthy, Raghu R.;
Nagaraj, Ram H.;
Stankowska, Dorota L.

Publication type:

Article

New Horizons in Research on Diabetic Complications of the Eye: Special Emphasis on Diabetic Cataracts and Retinopathy.

Published in:

Journal of Ophthalmology, 2010, p. 1, doi. 10.1155/2010/979040

By:

Hegde, Kavita R.;
Kowluru, Renu A.;
Mohr, Susanne;
Nagaraj, Ram H.;
Petrash, J. Mark

Publication type:

Article

Inhibition of Methylglyoxal-Mediated Protein Modification in Glyoxalase I Overexpressing Mouse Lenses.

Published in:

Journal of Ophthalmology, 2010, p. 1, doi. 10.1155/2010/274317

By:

Gangadhariah, Mahesha H.;
Mailankot, Maneesh;
Reneker, Lixing;
Nagaraj, Ram H.

Publication type:

Article

Candesartan Attenuates Diabetic Retinal Vascular Pathology by Restoring Glyoxalase-I Function.

Published in:

Diabetes, 2010, v. 59, n. 12, p. 3208, doi. 10.2337/db10-0552

By:

Miller, Antonia G.;
Tan, Genevieve;
Binger, Katrina J.;
Pickering, Raelene J.;
Thomas, Merlin C.;
Nagaraj, Ram H.;
Cooper, Mark E.;
Wilkinson-Berka, Jennifer L.

Publication type:

Article