Works matching AU Nadler, Jerry

Results: 74

Inflammatory mechanisms of diabetic complications.

Published in:

2007

By:

Williams, Michael;
Nadler, Jerry;
Williams, Michael D;
Nadler, Jerry L

Publication type:

journal article

Key Role of STAT4 Deficiency in the Hematopoietic Compartment in Insulin Resistance and Adipose Tissue Inflammation.

Published in:

Mediators of Inflammation, 2017, p. 1, doi. 10.1155/2017/5420718

By:

Dobrian, Anca D.;
Ma, Kaiwen;
Glenn, Lindsey M.;
Hatcher, Margaret A.;
Haynes, Bronson A.;
Lehrer, Eric J.;
Kaplan, Mark H.;
Nadler, Jerry L.

Publication type:

Article

STAT4 Play A Critical Role in Aging and High Fat Diet‐Associated Decline in Long‐Term, Activity‐Dependent Potentiation of Synaptic Transmission.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R3145

By:

Stanton, Patric K.;
Nadler, Jerry L.;
Zhang, Xiao‐lei;
Hollander, Callie;
Ma, Haoqin;
Yang, Xinyuan;
D'silva, Melinee;
Stahr, Natalie;
Moriarty, Alina;
Keeter, Coles;
Galkina, Elena V.

Publication type:

Article

12-Lipoxygenase Inhibition Improves Glycemia and Obesity-associated Inflammation in Male Human Gene Replacement Mice.

Published in:

Endocrinology, 2025, v. 166, n. 6, p. 1, doi. 10.1210/endocr/bqaf069

By:

Kaylan, Kerim B;
Nargis, Titli;
Figatner, Kayla;
Wang, Jiayi E;
Pratuangtham, Sarida;
Chakraborty, Advaita;
Casimiro, Isabel;
Nadler, Jerry L;
Boxer, Matthew B;
Maloney, David J;
Anderson, Ryan M;
Mirmira, Raghavendra G;
Tersey, Sarah A

Publication type:

Article

Eliminating or blocking 12/15-lipoxygenase reduces neutrophil recruitment in mouse models of acute lung inju.

Published in:

Critical Care, 2012, v. 16, n. 5, p. 1, doi. 10.1186/cc11518

By:

Rossaint, Jan;
Nadler, Jerry L.;
Ley, Klaus;
Zarbock, Alexander

Publication type:

Article

Eliminating or blocking 12/15-lipoxygenase reduces neutrophil recruitment in mouse models of acute lung injury.

Published in:

2012

By:

Rossaint, Jan;
Nadler, Jerry L;
Ley, Klaus;
Zarbock, Alexander

Publication type:

journal article

Role of inflammatory pathways in the development and cardiovascular complications of type 2 diabetes.

Published in:

Current Diabetes Reports, 2002, v. 2, n. 5, p. 396, doi. 10.1007/s11892-002-0103-5

By:

Huerta, Milagros;
Nadler, Jerry

Publication type:

Article

Response to Comment on Sims et al. Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes. Diabetes Care 2019;42:258-264.

Published in:

2019

By:

Sims, Emily K.;
Bahnson, Henry T.;
Nyalwidhe, Julius;
Haataja, Leena;
Davis, Asa K.;
Speake, Cate;
DiMeglio, Linda A.;
Blum, Janice;
Morris, Margaret A.;
Mirmira, Raghavendra G.;
Nadler, Jerry;
Mastracci, Teresa L.;
Marcovina, Santica;
Wei-Jun Qian;
Lian Yi;
Swensen, Adam C.;
Yip-Schneider, Michele;
Schmidt, C. Max;
Considine, Robert V.;
Arvan, Peter

Publication type:

Letter

Proinsulin Secretion Is a Persistent Feature of Type 1 Diabetes.

Published in:

2019

By:

Sims, Emily K.;
Bahnson, Henry T.;
Nyalwidhe, Julius;
Haataja, Leena;
Davis, Asa K.;
Speake, Cate;
DiMeglio, Linda A.;
Blum, Janice;
Morris, Margaret A.;
Mirmira, Raghavendra G..;
Nadler, Jerry;
Mastracci, Teresa L.;
Marcovina, Santica;
Wei-Jun Qian;
Lian Yi;
Swensen, Adam C.;
Yip-Schneider, Michele;
Schmidt, C. Max;
Considine, Robert V.;
Arvan, Peter

Publication type:

journal article

The unique hypusine modification of eIF5A promotes islet beta cell inflammation and dysfunction in mice.

Published in:

2010

By:

Maier, Bernhard;
Ogihara, Takeshi;
Trace, Anthony P.;
Tersey, Sarah A.;
Robbins, Reiesha D.;
Chakrabarti, Swarup K.;
Nunemaker, Craig S.;
Stull, Natalie D.;
Taylor, Catherine A.;
Thompson, John E.;
Dondero, Richard S.;
Lewis, Eli C.;
Dinarello, Charles A.;
Nadler, Jerry L.;
Mirmira, Raghavendra G.

Publication type:

journal article

Diabetes and Vascular Disease.

Published in:

Seminars in Cardiothoracic & Vascular Anesthesia, 2003, v. 7, n. 3, p. 295, doi. 10.1177/108925320300700306

By:

Plante, Deborah K.;
Nadler, Jerry L.

Publication type:

Article

Prevention, but not cure, of autoimmune diabetes in a NOD. scid transfer model by FTY720 despite effective modulation of blood T cells.

Published in:

Autoimmunity, 2011, v. 44, n. 2, p. 115, doi. 10.3109/08916934.2010.499885

By:

Morris, Margaret A.;
McDuffie, Marcia;
Nadler, Jerry L.;
Ley, Klaus

Publication type:

Article

Insulin Sensitivity and Insulin Clearance Are Heritable and Have Strong Genetic Correlation in Mexican Americans.

Published in:

Obesity (19307381), 2014, v. 22, n. 4, p. 1157, doi. 10.1002/oby.20639

By:

Goodarzi, Mark O.;
Langefeld, Carl D.;
Xiang, Anny H.;
Chen, Yii‐Der I.;
Guo, Xiuqing;
Hanley, Anthony J. G.;
Raffel, Leslie J.;
Kandeel, Fouad;
Nadler, Jerry L.;
Buchanan, Thomas A.;
Norris, Jill M.;
Fingerlin, Tasha E.;
Lorenzo, Carlos;
Rewers, Marian J.;
Haffner, Steven M.;
Bowden, Donald W.;
Rich, Stephen S.;
Bergman, Richard N.;
Rotter, Jerome I.;
Watanabe, Richard M.

Publication type:

Article

12/15-Lipoxygenase Products Induce Inflammation and Impair Insulin Signaling in 3T3-L1 Adipocytes.

Published in:

Obesity (19307381), 2009, v. 17, n. 9, p. 1657, doi. 10.1038/oby.2009.192

By:

Chakrabarti, Swarup K.;
Cole, Banumathi K.;
Yeshao Wen;
Keller, Susanna R.;
Nadler, Jerry L.

Publication type:

Article

Complement Activation and STAT4 Expression Are Associated with Early Inflammation in Diabetic Wounds.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0170500

By:

Cunnion, Kenji M.;
Krishna, Neel K.;
Pallera, Haree K.;
Pineros-Fernandez, Angela;
Rivera, Magdielis Gregory;
Hair, Pamela S.;
Lassiter, Brittany P.;
Huyck, Ryan;
Clements, Mary A.;
Hood, Antoinette F.;
Rodeheaver, George T.;
Cottler, Patrick S.;
Nadler, Jerry L.;
Dobrian, Anca D.

Publication type:

Article

Macrophage-specific lipoxygenase deletion amplify cardiac repair activating T<sub>reg</sub> cells in chronic heart failure.

Published in:

Journal of Leukocyte Biology, 2024, v. 116, n. 4, p. 864, doi. 10.1093/jleuko/qiae113

By:

Kain, Vasundhara;
Grilo, Gabriel Araujo;
Upadhyay, Gunjan;
Nadler, Jerry L;
Serhan, Charles N;
Halade, Ganesh V

Publication type:

Article

Magnesium Deficiency Is Associated With Insulin Resistance in Obese Children.

Published in:

Diabetes Care, 2005, v. 28, n. 5, p. 1175, doi. 10.2337/diacare.28.5.1175

By:

Huerta, Milagros G.;
Roemmich, James N.;
Kington, Marit L.;
Bovbjerg, Viktor E.;
Weltman, Arthur L.;
Holmes, Viola F.;
Patrie, James T.;
Rogol, Alan D.;
Nadler, Jerry L.

Publication type:

Article

Translating lifestyle intervention to practice in obese patients with type 2 diabetes: Improving Control with Activity and Nutrition (ICAN) study.

Published in:

2004

By:

Wolf AM;
Conaway MR;
Crowther JQ;
Hazen KY;
Nadler JL;
Oneida B;
Bovbjerg VE;
Wolf, Anne M;
Conaway, Mark R;
Crowther, Jayne Q;
Hazen, Kristen Y;
L Nadler, Jerry;
Oneida, Beverly;
Bovbjerg, Viktor E;
Improving Control with Activity and Nutrition (ICAN) Study

Publication type:

journal article

Translating Lifestyle Intervention to Practice in Obese Patients With Type 2 Diabetes.

Published in:

Diabetes Care, 2004, v. 27, n. 7, p. 1570, doi. 10.2337/diacare.27.7.1570

By:

Wolf, Anne M.;
Conaway, Mark R.;
Crowther, Jayne Q.;
Hazen, Kristen Y.;
Nadler, Jerry L.;
Oneida, Beverly;
Bovbjerg, Viktor E.

Publication type:

Article

A new dietary approach to reduce the risk of type 2 diabetes?

Published in:

2004

By:

Nadler, Jerry L.

Publication type:

commentary

Comparative quantitative proteomic analysis of disease stratified laser captured microdissected human islets identifies proteins and pathways potentially related to type 1 diabetes.

Published in:

PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0183908

By:

Nyalwidhe, Julius O.;
Grzesik, Wojciech J.;
Burch, Tanya C.;
Semeraro, Michele L.;
Waseem, Tayab;
Gerling, Ivan C.;
Mirmira, Raghavendra G.;
Morris, Margaret A.;
Nadler, Jerry L.

Publication type:

Article

Evidence for 12-lipoxygenase induction in the vessel wall following balloon injury.

Published in:

Cardiovascular Research, 1999, v. 41, n. 2, p. 489, doi. 10.1016/S0008-6363(98)00312-5

By:

Natarajan, Rama;
Pei, Hong;
Gu, Jia-Li;
Sarma, Jonnalegedda M.;
Nadler, Jerry

Publication type:

Article

Bariatric Surgery Decreases Monocyte-Platelet Aggregates in Blood: a Pilot Study.

Published in:

Obesity Surgery, 2014, v. 24, n. 8, p. 1410, doi. 10.1007/s11695-014-1278-y

By:

Periasamy, Monica;
Lieb, David;
Butcher, Matthew;
Kuhn, Norine;
Galkina, Elena;
Fontana, Mark;
Wohlgemuth, Stephen;
Nadler, Jerry;
Dobrydneva, Yuliya

Publication type:

Article

Adipose Tissue-Specific Deletion of 12/15-Lipoxygenase Protects Mice from the Consequences of a High-Fat Diet.

Published in:

Mediators of Inflammation, 2012, v. 2012, p. 1, doi. 10.1155/2012/851798

By:

Cole, Banumathi K.;
Morris, Margaret A.;
Grzesik, Wojciech J.;
Leone, Kendall A.;
Nadler, Jerry L.

Publication type:

Article

Insulin resistance elicited in postpubertal primate offspring deprived of estrogen in utero.

Published in:

Endocrine (1355008X), 2016, v. 54, n. 3, p. 788, doi. 10.1007/s12020-016-1145-9

By:

Pepe, Gerald;
Maniu, Adina;
Aberdeen, Graham;
Lynch, Terrie;
Kim, Soon;
Nadler, Jerry;
Albrecht, Eugene

Publication type:

Article

12-Lipoxygenase Inhibitor Improves Functions of Cytokine-Treated Human Islets and Type 2 Diabetic Islets.

Published in:

2017

By:

Ma, Kaiwen;
Park, So Hyun;
Lindsey, Glenn;
Laura, Jackson;
Tatvam, Barot;
Weaver, Jessica R;
Taylor-Fishwick, David A;
Luci, Diane K;
Maloney, David J;
Mirmira, Raghavendra G;
Imai, Yumi;
Nadler, Jerry L;
Xiao, An;
Glenn, Lindsey;
Jackson, Laura;
Barot, Tatvam

Publication type:

journal article

Expression pattern of 12-lipoxygenase in human islets with type 1 diabetes and type 2 diabetes.

Published in:

2015

By:

Grzesik, Wojciech J;
Nadler, Joseph L;
Machida, Yui;
Nadler, Jerry L;
Imai, Yumi;
Morris, Margaret A

Publication type:

journal article

Adipose tissue 12/15 lipoxygenase pathway in human obesity and diabetes.

Published in:

2014

By:

Lieb, David C;
Brotman, Joshua J;
Hatcher, Margaret A;
Aye, Myo S;
Cole, Banumathi K;
Haynes, Bronson A;
Wohlgemuth, Stephen D;
Fontana, Mark A;
Beydoun, Hind;
Nadler, Jerry L;
Dobrian, Anca D

Publication type:

journal article

12-Lipoxygenase Promotes Obesity-Induced Oxidative Stress in Pancreatic Islets.

Published in:

Molecular & Cellular Biology, 2014, v. 34, n. 19, p. 3735, doi. 10.1128/MCB.00157-14

By:

Tersey, Sarah A.;
Maier, Bernhard;
Yurika Nishiki;
Maganti, Aarthi V.;
Nadler, Jerry L.;
Mirmira, Raghavendra G.

Publication type:

Article

Joint analysis of the nPOD-Virus Group data: the association of enterovirus with type 1 diabetes is supported by multiple markers of infection in pancreas tissue.

Published in:

Diabetologia, 2025, v. 68, n. 6, p. 1226, doi. 10.1007/s00125-025-06401-x

By:

Richardson, Sarah J.;
Rodriguez-Calvo, Teresa;
Laiho, Jutta E.;
Kaddis, John S.;
Nyalwidhe, Julius O.;
Kusmartseva, Irina;
Morfopoulou, Sofia;
Petrosino, Joseph F.;
Plagnol, Vincent;
Maedler, Kathrin;
Morris, Margaret A.;
Nadler, Jerry L.;
Atkinson, Mark A.;
von Herrath, Matthias;
Lloyd, Richard E.;
Hyoty, Heikki;
Morgan, Noel G.;
Pugliese, Alberto

Publication type:

Article

Lipids and immunoinflammatory pathways of beta cell destruction.

Published in:

Diabetologia, 2016, v. 59, n. 4, p. 673, doi. 10.1007/s00125-016-3890-y

By:

Imai, Yumi;
Dobrian, Anca;
Morris, Margaret;
Taylor-Fishwick, David;
Nadler, Jerry

Publication type:

Article

Selective inhibition of 12-lipoxygenase protects islets and beta cells from inflammatory cytokine-mediated beta cell dysfunction.

Published in:

Diabetologia, 2015, v. 58, n. 3, p. 549, doi. 10.1007/s00125-014-3452-0

By:

Taylor-Fishwick, David;
Weaver, Jessica;
Glenn, Lindsey;
Kuhn, Norine;
Rai, Ganesha;
Jadhav, Ajit;
Simeonov, Anton;
Dudda, Angela;
Schmoll, Dieter;
Holman, Theodore;
Maloney, David;
Nadler, Jerry

Publication type:

Article

The AAV-PCSK9 murine model of atherosclerosis and metabolic dysfunction.

Published in:

European Heart Journal Open, 2022, v. 2, n. 3, p. 1, doi. 10.1093/ehjopen/oeac028

By:

Keeter, William Coles;
Carter, Nigeste M.;
Nadler, Jerry L.;
Galkina, Elena V.

Publication type:

Article

Viral IL-10-Mediated Immune Regulation in Pancreatic Islet Transplantation

Published in:

Molecular Therapy, 2005, v. 12, n. 2, p. 360, doi. 10.1016/j.ymthe.2005.02.030

By:

Carter, Jeffrey D.;
Ellett, Justin D.;
Chen, Meng;
Smith, Kellie M.;
Fialkow, Lawrence B.;
McDuffie, Marcia J.;
Tung, Kenneth S.;
Nadler, Jerry L.;
Yang, Zandong

Publication type:

Article

Regulation of Tissue Inflammation by 12-Lipoxygenases.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 5, p. 717, doi. 10.3390/biom11050717

By:

Kulkarni, Abhishek;
Nadler, Jerry L.;
Mirmira, Raghavendra G.;
Casimiro, Isabel;
Kokotos, George;
Ramanadham, Sasanka

Publication type:

Article

The severity of SARS‐CoV‐2 infection in K18‐hACE2 mice is attenuated by a novel steroid‐derivative in a gender‐specific manner.

Published in:

British Journal of Pharmacology, 2023, v. 180, n. 20, p. 2677, doi. 10.1111/bph.16155

By:

Gupte, Sachin A.;
Bakshi, Chandra Shekhar;
Blackham, Emma;
Duhamel, Gerald E.;
Jordan, Allan;
Salgame, Padmini;
D'silva, Melinee;
Khan, Mohammad Y.;
Nadler, Jerry;
Gupte, Rakhee

Publication type:

Article

12-Lipoxygenase is increased in glucose-stimulated mesangial cells and in experimental diabetic nephropathy.

Published in:

Kidney International, 2001, v. 59, n. 4, p. 1354, doi. 10.1046/j.1523-1755.2001.0590041354.x

By:

Kang, Shin-Wook;
Adler, Sharon G.;
Nast, Cynthia C.;
Lapage, Janine;
Gu, Jia-Li;
Nadler, Jerry L.;
Natarajan, Rama

Publication type:

Article

Inhibition of STAT4 Activation by Lisofylline Is Associated with the Protection of Autoimmune Diabetes.

Published in:

Annals of the New York Academy of Sciences, 2003, v. 1005, n. 1, p. 409, doi. 10.1196/annals.1288.069

By:

YANG, ZANDONG;
CHEN, MENG;
FIALKOW, LAWRENCE B.;
ELLETT, JUSTIN D.;
WU, RUNPEI;
NADLER, JERRY L.

Publication type:

Article

Lifestyle Intervention in Obese Patients with Type 2 Diabetes: Impact of the Patient's Educational Background<sup>*</sup>.

Published in:

Obesity (19307381), 2006, v. 14, n. 6, p. 1085, doi. 10.1038/oby.2006.124

By:

Gurka, Matthew J.;
Wolf, Anne M.;
Conaway, Mark R.;
Crowther, Jayne Q.;
Nadler, Jerry L.;
Bovbjerg, Viktor E.

Publication type:

Article

Weight‐loss surgery rapidly alleviates platelet hyperactivity in morbid obesity.

Published in:

FASEB Journal, 2013, v. 27, p. 1114.1, doi. 10.1096/fasebj.27.1_supplement.1114.1

By:

Dobrydneva, Yuliya;
Periasamy, Monica;
Butcher, Matthew;
Galkina, Elena;
Kuhn, Norine;
Lieb, David;
Fontana, Mark;
Wohlgemuth, Steven;
Nadler, Jerry

Publication type:

Article

12/15-lipoxygenase and diabetic neuropathy.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1273, doi. 10.1096/fasebj.21.6.a1273-a

By:

Obrosova, Irina G.;
Jeho Shin;
Lyzogubov, Valeriy V.;
Nadler, Jerry L.;
Drel, Viktor R.

Publication type:

Article

A key role of 12/15-Lipoxygenase in acute lung injury (ALI).

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1202, doi. 10.1096/fasebj.21.6.a1202

By:

Zarbock, Alexander;
Smith, Emily;
Kronke, Gerhard;
Harry, Brian;
Hedrick, Catherine;
Nadler, Jerry;
Ley, Klaus

Publication type:

Article

Inhibition of 12/15-Lipoxygenase Protects Against β-Cell Oxidative Stress and Glycemic Deterioration in Mouse Models of Type 1 Diabetes.

Published in:

2017

By:

Hernandez-Perez, Marimar;
Chopra, Gaurav;
Fine, Jonathan;
Conteh, Abass M.;
Anderson, Ryan M.;
Linnemann, Amelia K.;
Benjamin, Chanelle;
Nelson, Jennifer B.;
Benninger, Kara S.;
Nadler, Jerry L.;
Maloney, David J.;
Tersey, Sarah A.;
Mirmira, Raghavendra G.

Publication type:

journal article

STAT4 Deficiency Reduces Obesity-Induced Insulin Resistance and Adipose Tissue Inflammation.

Published in:

Diabetes, 2013, v. 62, n. 12, p. 4109, doi. 10.2337/db12-1275

By:

Dobrian, Anca D.;
Galkina, Elena V.;
Ma, Qian;
Hatcher, Margaret;
Aye, Sabai Myo;
Butcher, Mathew J.;
Ma, Kaiwen;
Haynes, Bronson A.;
Kaplan, Mark H.;
Nadler, Jerry L.

Publication type:

Article

5-Lipoxygenase, but Not 12/15-Lipoxygenase, Contributes to Degeneration of Retinal Capillaries in a Mouse Model of Diabetic Retinopathy.

Published in:

Diabetes, 2008, v. 57, n. 5, p. 1387, doi. 10.2337/db07-1217

By:

Gubitosi-Klug, Rose A.;
Talahalli, Ramaprasad;
Du, Yunpeng;
Nadler, Jerry L.;
Kern, Timothy S.

Publication type:

Article

Nonobese Diabetic (NOD) Mice Congenic for a Targeted Deletion of 12/15-Lipoxygenase Are Protected From Autoimmune Diabetes.

Published in:

Diabetes, 2008, v. 57, n. 1, p. 199, doi. 10.2337/db07-0830

By:

McDuffie, Marcia;
Maybee, Nelly A.;
Keller, Susanna R.;
Stevens, Brian K.;
Garmey, James C.;
Morris, Margaret A.;
Kropf, Elizabeth;
Rival, Claudia;
Ma, Kaiwen;
Carter, Jeffrey D.;
Tersey, Sarah A.;
Nunemaker, Craig S.;
Nadler, Jerry L.

Publication type:

Article

High-fat diet induced neuropathy of pre-diabetes and obesity: effects of "healthy" diet and aldose reductase inhibition.

Published in:

2007

By:

Obrosova IG;
Ilnytska O;
Lyzogubov VV;
Pavlov IA;
Mashtalir N;
Nadler JL;
Drel VR;
Obrosova, Irina G;
Ilnytska, Olga;
Lyzogubov, Valeriy V;
Pavlov, Ivan A;
Mashtalir, Nazar;
Nadler, Jerry L;
Drel, Viktor R

Publication type:

journal article

High-Fat Diet-Induced Neuropathy of Pre-Diabetes and Obesity.

Published in:

Diabetes, 2007, v. 56, n. 10, p. 2598, doi. 10.2337/db06-1176

By:

Obrosova, Irina G.;
Ilnytska, Olga;
Lyzogubov, Valeriy V.;
Pavlov, Ivan A.;
Mashtalir, Nazar;
Nadler, Jerry L.;
Drel, Viktor R.

Publication type:

Article

Role of Inflammation, Oxidative Stress and Adipokines in the Development of Insulin Resistance and Altered Glucose Homeostasis in Obese Youth.

Published in:

Diabetes, 2007, v. 56, p. A487

By:

Huerta, Milagros;
Jaques, Cory;
Mendosa, Pamela;
Wasserfall, Clive;
Silverstein, Janet;
Atkinson, Mark;
Nadler, Jerry

Publication type:

Article

Pancreatic Islets From Mice Overexpressing 12-Lipoxygenase Show Increased Cell Death.

Published in:

Diabetes, 2007, v. 56, p. A441

By:

Nunemaker, Craig S.;
Wu, Runpei;
Jahanshahi, Pooya;
Carter, Jeffrey D.;
Chakrabarti, Swarup K.;
Nadler, Jerry L.

Publication type:

Article