Works matching AU Nada, Hossam

Results: 20

Development of New Meridianin/Leucettine-Derived Hybrid Small Molecules as Nanomolar Multi-Kinase Inhibitors with Antitumor Activity.

Published in:

Biomedicines, 2021, v. 9, n. 9, p. 1131, doi. 10.3390/biomedicines9091131

By:

Elsherbeny, Mohamed H.;
Elkamhawy, Ahmed;
Nada, Hossam;
Abdellattif, Magda H.;
Lee, Kyeong;
Roh, Eun Joo

Publication type:

Article

Small Molecules in Parkinson's Disease Therapy: From Dopamine Pathways to New Emerging Targets.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 12, p. 1688, doi. 10.3390/ph17121688

By:

Lee, Hwayoung;
Elkamhawy, Ahmed;
Rakhalskaya, Polina;
Lu, Qili;
Nada, Hossam;
Quan, Guofeng;
Lee, Kyeong

Publication type:

Article

Design, Synthesis and Biological Evaluation of Novel MDH Inhibitors Targeting Tumor Microenvironment.

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 5, p. 683, doi. 10.3390/ph16050683

By:

Godesi, Sreenivasulu;
Han, Jeong-Ran;
Kim, Jang-Keun;
Kwak, Dong-Ik;
Lee, Joohan;
Nada, Hossam;
Kim, Minkyoung;
Yang, Hyun-A;
Im, Joo-Young;
Ban, Hyun Seung;
Lee, Chang Hoon;
Choi, Yongseok;
Won, Misun;
Lee, Kyeong

Publication type:

Article

Hit Identification of a Novel Quinazoline Sulfonamide as a Promising EphB3 Inhibitor: Design, Virtual Combinatorial Library, Synthesis, Biological Evaluation, and Docking Simulation Studies.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 12, p. 1247, doi. 10.3390/ph14121247

By:

Lee, Kyeong;
Nada, Hossam;
Byun, Hyun Jung;
Lee, Chang Hoon;
Elkamhawy, Ahmed

Publication type:

Article

4-Anilinoquinazoline-based benzenesulfonamides as nanomolar inhibitors of carbonic anhydrase isoforms I, II, IX, and XII: design, synthesis, in-vitro, and in-silico biological studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 994, doi. 10.1080/14756366.2022.2055553

By:

Nada, Hossam;
Elkamhawy, Ahmed;
Abdellattif, Magda H.;
Angeli, Andrea;
Chang Hoon Lee;
Supuran, Claudiu T.;
Kyeong Lee

Publication type:

Article

Inhibition studies on a panel of human carbonic anhydrases with N1-substituted secondary sulfonamides incorporating thiazolinone or imidazolone-indole tails.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 629, doi. 10.1080/14756366.2018.1446432

By:

Awadallah, Fadi M.;
Bua, Silvia;
Mahmoud, Walaa R.;
Nada, Hossam H.;
Nocentini, Alessio;
Supuran, Claudiu T.

Publication type:

Article

Small Molecule c-KIT Inhibitors for the Treatment of Gastrointestinal Stromal Tumors: A Review on Synthesis, Design Strategies, and Structure–Activity Relationship (SAR).

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9450, doi. 10.3390/ijms24119450

By:

Godesi, Sreenivasulu;
Lee, Joohan;
Nada, Hossam;
Quan, Guofeng;
Elkamhawy, Ahmed;
Choi, Yongseok;
Lee, Kyeong

Publication type:

Article

Identification of Novel and Potent Indole-Based Benzenesulfonamides as Selective Human Carbonic Anhydrase II Inhibitors: Design, Synthesis, In Vitro, and In Silico Studies.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 5, p. 2540, doi. 10.3390/ijms23052540

By:

Elkamhawy, Ahmed;
Woo, Jiyu;
Nada, Hossam;
Angeli, Andrea;
Bedair, Tarek M.;
Supuran, Claudiu T.;
Lee, Kyeong

Publication type:

Article

The Journey of DDR1 and DDR2 Kinase Inhibitors as Rising Stars in the Fight Against Cancer.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 12, p. 6535, doi. 10.3390/ijms22126535

By:

Elkamhawy, Ahmed;
Lu, Qili;
Nada, Hossam;
Woo, Jiyu;
Quan, Guofeng;
Lee, Kyeong

Publication type:

Article

New insights into protein–protein interaction modulators in drug discovery and therapeutic advance.

Published in:

Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-02036-3

By:

Nada, Hossam;
Choi, Yongseok;
Kim, Sungdo;
Jeong, Kwon Su;
Meanwell, Nicholas A.;
Lee, Kyeong

Publication type:

Article

Cantharidin-Based Verbenone Derivatives as a Novel Insecticide against Plutella xylostella : Design, Synthesis, Insecticidal Activity Evaluation, and 3D QSAR Study.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 8, p. 1272, doi. 10.3390/biom13081272

By:

Lee, Kwanshik;
Nada, Hossam;
Kim, Minkyoung;
Park, Hyejun;
Lee, Kiho;
Seo, Dongho;
Lee, Kyeong;
Choi, Yongseok

Publication type:

Article

Identification of 1H-purine-2,6-dione derivative as a potential SARS-CoV-2 main protease inhibitor: molecular docking, dynamic simulations, and energy calculations.

Published in:

PeerJ, 2022, p. 1, doi. 10.7717/peerj.14120

By:

Nada, Hossam;
Elkamhawy, Ahmed;
Kyeong Lee

Publication type:

Article

Melatonin Analogues Potently Inhibit MAO-B and Protect PC12 Cells against Oxidative Stress.

Published in:

Antioxidants, 2021, v. 10, n. 10, p. 1604, doi. 10.3390/antiox10101604

By:

Elkamhawy, Ahmed;
Woo, Jiyu;
Gouda, Noha A.;
Kim, Jushin;
Nada, Hossam;
Roh, Eun Joo;
Park, Ki Duk;
Cho, Jungsook;
Lee, Kyeong

Publication type:

Article

Virtual screening: hope, hype, and the fine line in between.

Published in:

Expert Opinion on Drug Discovery, 2025, v. 20, n. 2, p. 145, doi. 10.1080/17460441.2025.2458666

By:

Nada, Hossam;
Meanwell, Nicholas A.;
Gabr, Moustafa T.

Publication type:

Article

Chalcone‐based benzenesulfonamides as potent and selective inhibitors for human carbonic anhydrase II: Design, synthesis, in vitro, and in silico studies.

Published in:

Archiv der Pharmazie, 2024, v. 357, n. 11, p. 1, doi. 10.1002/ardp.202400069

By:

Lee, Hwa Young;
Elkamhawy, Ahmed;
Al‐Karmalawy, Ahmed A.;
Nada, Hossam;
Giovannuzzi, Simone;
Supuran, Claudiu T.;
Lee, Kyeong

Publication type:

Article

A novel indole derivative, 2‐{3‐[1‐(benzylsulfonyl)piperidin‐4‐yl]‐2‐methyl‐1H‐indol‐1‐yl}‐1‐(pyrrolidin‐1‐yl)ethenone, suppresses hedgehog signaling and drug‐resistant tumor growth

Published in:

Archiv der Pharmazie, 2024, v. 357, n. 10, p. 1, doi. 10.1002/ardp.202400218

By:

Jung, Joo Hyun;
Lee, Hwayoung;
Jeon, Jiyeon;
Lee, Yoon Ji;
Nada, Hossam;
Kim, Minkyoung;
Lee, Hankyu;
Bhattarai, Deepak;
Lee, Kyeong;
Ko, Hyuk Wan

Publication type:

Article

Natural products as IL‐6 inhibitors for inflammatory diseases: Synthetic and SAR perspective.

Published in:

Medicinal Research Reviews, 2024, v. 44, n. 4, p. 1683, doi. 10.1002/med.22022

By:

Harmalkar, Dipesh S.;
Sivaraman, Aneesh;
Nada, Hossam;
Lee, Joohan;
Kang, Hyeseul;
Choi, Yongseok;
Lee, Kyeong

Publication type:

Article

Discovery and optimization of natural-based nanomolar c-Kit inhibitors via in silico and in vitro studies.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 21, p. 11904, doi. 10.1080/07391102.2022.2164061

By:

Nada, Hossam;
Kim, Sungdo;
Godesi, Sreenivasulu;
Lee, Joohan;
Lee, Kyeong

Publication type:

Article

Integration of Hybridization Strategies in Pyridine–Urea Scaffolds for Novel Anticancer Agents: Design, Synthesis, and Mechanistic Insights.

Published in:

Molecules, 2023, v. 28, n. 13, p. 4952, doi. 10.3390/molecules28134952

By:

Godesi, Sreenivasulu;
Nada, Hossam;
Lee, Joohan;
Kang, Joon-Hee;
Kim, Soo-Youl;
Choi, Yongseok;
Lee, Kyeong

Publication type:

Article

Structure Activity Relationship of Key Heterocyclic Anti-Angiogenic Leads of Promising Potential in the Fight against Cancer.

Published in:

Molecules, 2021, v. 26, n. 3, p. 553, doi. 10.3390/molecules26030553

By:

Nada, Hossam;
Elkamhawy, Ahmed;
Lee, Kyeong;
Muñoz-Torrero, Diego

Publication type:

Article