Works by NISKANEN, LEO

Results: 143

Renal Hyperfiltration as a New Mechanism of Smoking-Related Mortality Open Access.

Published in:

Nicotine & Tobacco Research, 2025, v. 27, n. 6, p. 1092, doi. 10.1093/ntr/ntae136

By:

Aissani, Mohamed Smail;
Niskanen, Leo;
Tuomainen, Tomi-Pekka;
Setti, Mounir Ould

Publication type:

Article

Reduced Serum Adiponectin Levels in Alexithymia.

Published in:

Neuroimmunomodulation, 2014, v. 21, n. 5, p. 234, doi. 10.1159/000357051

By:

Honkalampi, Kirsi;
Viinamäki, Heimo;
Niskanen, Leo;
Koivumaa-Honkanen, Heli;
Valkonen-Korhonen, Minna;
Elomaa, antti-Pekka;
Harvima, Ilkka;
Herzig, Karl-Heinz;
Lehto, Soili M.

Publication type:

Article

Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels.

Published in:

Nature Medicine, 1998, v. 4, n. 12, p. 1434, doi. 10.1038/4027

By:

Karvonen, Matti K.;
Pesonen, Ullamari;
Koulu, Markku;
Niskanen, Leo;
Laakso, Markku;
Rissanen, Aila;
Dekker, Jacqueline M.;
Hart, Leen M ´t;
Valve, Raisa;
Uusitupa, Matti I.J.

Publication type:

Article

Quality of Life in Treated Patients with Acromegaly.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2006, v. 91, n. 10, p. 3891, doi. 10.1210/jc.2006-0676

By:

Kauppinen-Mäkelin, Ritva;
Sane, Timo;
Sintonen, Harri;
Markkanen, Helene;
Välimäki, Matti J.;
Löyttyniemi, Eliisa;
Niskanen, Leo;
Reunanen, Antti;
Stenman, Ulf-Håkan

Publication type:

Article

A Nationwide Survey of Mortality in Acromegaly.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 7, p. 4081, doi. 10.1210/jc.2004-1381

By:

Kauppinen-Mäkelin, Ritva;
Sane, Timo;
Reunanen, Antti;
Välimäki, Matti J.;
Niskanen, Leo;
Markkanen, Helene;
Löyttyniemi, Eliisa;
Ebeling, Tapani;
Jaatinen, Pia;
Laine, Hanna;
Nuutila, Pirjo;
Salmela, Pasi;
Salmi, Jorma;
Stenman, Ulf-Håkan;
Viikari, Jorma;
Voutilainen, Erkki

Publication type:

Article

The Metabolic Syndrome and Smoking in Relation to Hypogonadism in Middle-Aged Men: A Prospective Cohort Study.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2005, v. 90, n. 2, p. 712, doi. 10.1210/jc.2004-0970

By:

Laaksonen, David E.;
Niskanen, Leo;
Punnonen, Kari;
Nyyssönen, Kristiina;
Tuomainen, Tomi-Pekka;
Valkonen, Veli-Pekka;
Salonen, Jukka T.

Publication type:

Article

Expression and Prognostic Value of α-, β-, and γ-Catenins in Differentiated Thyroid Carcinoma.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2000, v. 85, n. 12, p. 4806, doi. 10.1210/jc.85.12.4806

By:

BÖHM, JAN;
NISKANEN, LEO;
KIRALY, KARI;
KELLOKOSKI, JARI;
ESKELINEN, MATTI;
HOLLMEN, SINIKKA;
ALHAVA, ESKO;
KOSMA, VELI-MATTI

Publication type:

Article

Leucine 7 to Proline 7 Polymorphism in the Neuropeptide Y Gene Is Associated with Enhanced Carotid Atherosclerosis in Elderly Patients with Type 2 Diabetes and Control Subjects.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2000, v. 85, n. 6, p. 2266, doi. 10.1210/jcem.85.6.6633

By:

NISKANEN, LEO;
KARVONEN, MATTI K.;
VALVE, RAISA;
KOULU, MARKKU;
PESONEN, ULLAMARI;
MERCURI, MICHELE;
RAURAMAA, RAINER;
TÖYRY, JARI;
LAAKSO, MARKKU;
UUSITUPA, MATTI I. J.

Publication type:

Article

Biochemical Bone Markers and Bone Mineral Density during Postmenopausal Hormone Replacement Therapy with and without Vitamin D<sub>3</sub>: A Prospective, Controlled, Randomized Study.

Published in:

Journal of Clinical Endocrinology & Metabolism, 1997, v. 82, n. 8, p. 2476, doi. 10.1210/jcem.82.8.4177

By:

HEIKKINEN, ANNA-MARI;
PARVIAINEN, MARKKU;
NISKANEN, LEO;
KOMULAINEN, MARJA;
TUPPURAINEN, MARJO T.;
KRÖGER, HEIKKI;
SAARIKOSKI, SEPPO

Publication type:

Article

Divergent pathologies and treatment options for diabetic neuropathies.

Published in:

2020

By:

Uusitupa, Matti;
Niskanen, Leo;
Laitinen, Tomi

Publication type:

Letter

Androgen receptor gene CAG repeat length in women with metabolic syndrome.

Published in:

Gynecological Endocrinology, 2008, v. 24, n. 7, p. 411, doi. 10.1080/09513590802210865

By:

Jääskeläinen, Jarmo;
Korhonen, Seija;
Kuulasmaa, Tiina;
Kurl, Sangita;
Niskanen, Leo;
Vanhala, Matti;
Hippeläinen, Maritta;
Voutilainen, Raimo;
Heinonen, Seppo

Publication type:

Article

A nationwide study on parathyroid carcinoma.

Published in:

Acta Oncologica, 2017, v. 56, n. 7, p. 991, doi. 10.1080/0284186X.2017.1306103

By:

Ryhänen, Eeva M.;
Leijon, Helena;
Metso, Saara;
Eloranta, Eija;
Korsoff, Pirkko;
Ahtiainen, Petteri;
Kekäläinen, Päivi;
Tamminen, Marjo;
Ristamäki, Raija;
Knutar, Otto;
Löyttyniemi, Eliisa;
Niskanen, Leo;
Väisänen, Mika;
Heiskanen, Ilkka;
Välimäki, Matti J.;
Laakso, Markku;
Haglund, Caj;
Arola, Johanna;
Schalin-Jäntti, Camilla

Publication type:

Article

Improved control of blood pressure and albuminuria among patients with type-2 diabetes in Finnish open care.

Published in:

Blood Pressure, 2017, v. 26, n. 2, p. 67, doi. 10.1080/08037051.2016.1190917

By:

Varis, Juha;
Metsärinne, Kaj;
Koivisto, Veikko;
Niskanen, Leo;
Rissanen, Aila;
Virkamäki, Antti;
Appelroth, Tina;
Pöntynen, Nora;
Poussa, Tuija;
Kantola, Ilkka

Publication type:

Article

Plasma aldosterone to renin ratio predicts treatment response in primary aldosteronism: Is volume loading needed?

Published in:

Blood Pressure, 2005, v. 14, n. 4, p. 245, doi. 10.1080/08037050510034329

By:

Juutilainen, Auni M.;
Voutilainen, Erkki T.;
Mykkänen, Leena;
Niskanen, Leo

Publication type:

Article

The Captopril Prevention Project (CAPPP) in Hypertension-Baseline Data and Current Status.

Published in:

Blood Pressure, 1997, v. 6, n. 6, p. 365, doi. 10.3109/08037059709062096

By:

Hansson, Lennart;
Hedner, Thomas;
Lindholm, Lars;
Niklason, Anders;
Luomanmäki, Kimmo;
Niskanen, Leo;
Lanke, Jan;
Dahlöf, Björn;
Faire, Ulf De;
Mörlin, Claes;
Karlberg, Bengt E.;
Wester, P. O.;
Björck, Jan-Erik;
The Cappp Study Group

Publication type:

Article

The effectiveness of teriparatide in the clinical practice-attenuation of the bone mineral density outcome by increasing age and bisphosphonate pretreatment.

Published in:

Annals of Medicine, 2013, v. 45, n. 3, p. 230, doi. 10.3109/07853890.2012.742560

By:

Koski, Anna-Mari;
Löyttyniemi, Eliisa;
Väänänen, Hannu;
Laine, Hanna;
Niskanen, Leo;
Nevalainen, Pasi I.;
Korpi-Hyövälti, Eeva;
Välimäki, Matti J.

Publication type:

Article

Long-term repeatability of measures of early insulin secretion derived from an intravenous glucose tolerance test and conversion from impaired glucose tolerance to diabetes.

Published in:

Annals of Medicine, 2008, v. 40, n. 4, p. 303, doi. 10.1080/07853890701879808

By:

Laaksonen, David E.;
Niskanen, Leo;
Mykkänen, Hannu;
Juntunen, Katri S.;
Schwab, Ursula;
Kolehmainen, Marjukka;
Rauramaa, Rainer;
Tuomilehto, Jaakko;
Uusitupa, Matti

Publication type:

Article

Epidemiology and treatment of the metabolic syndrome.

Published in:

Annals of Medicine, 2004, v. 36, n. 5, p. 332, doi. 10.1080/07853890410031849

By:

Laaksonen, David E.;
Niskanen, Leo;
Lakka, Hanna-Maaria;
Lakka, Timo A.;
Uusitupa, Matti

Publication type:

Article

Association of Serum 25-Hydroxyvitamin D with Lifestyle Factors and Metabolic and Cardiovascular Disease Markers: Population-Based Cross-Sectional Study (FIN-D2D).

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0100235

By:

Miettinen, Maija E.;
Kinnunen, Leena;
Leiviskä, Jaana;
Keinänen-Kiukaanniemi, Sirkka;
Korpi-Hyövälti, Eeva;
Niskanen, Leo;
Oksa, Heikki;
Saaristo, Timo;
Tuomilehto, Jaakko;
Vanhala, Mauno;
Uusitupa, Matti;
Peltonen, Markku

Publication type:

Article

A pharmacoepidemiological nested case-control study of risk factors for venous thromboembolism with the focus on diabetes, cancer, socioeconomic group, medications, and comorbidities.

Published in:

Diabetes & Vascular Disease Research, 2024, v. 21, n. 3, p. 1, doi. 10.1177/14791641241236894

By:

Myllylahti, Lasse;
Niskanen, Leo;
Lassila, Riitta;
Haukka, Jari

Publication type:

Article

C-reactive protein in the prediction of cardiovascular and overall mortality in middle-aged men: a population-based cohort study.

Published in:

European Heart Journal, 2005, v. 26, n. 17, p. 1783, doi. 10.1093/eurheartj/ehi237

By:

Laaksonen, David E.;
Niskanen, Leo;
Nyyssönen, Kristiina;
Punnonen, Kari;
Tuomainen, Tomi-Pekka;
Salonen, Jukka T.

Publication type:

Article

Alexithymia and tissue inflammation.

Published in:

2011

By:

Honkalampi, Kirsi;
Lehto, Soili M;
Koivumaa-Honkanen, Heli;
Hintikka, Jukka;
Niskanen, Leo;
Valkonen-Korhonen, Minna;
Viinamäki, Heimo

Publication type:

Journal Article

Alexithymia and Tissue Inflammation.

Published in:

Psychotherapy & Psychosomatics, 2011, v. 80, n. 6, p. 359, doi. 10.1159/000327583

By:

Honkalampi, Kirsi;
Lehto, Soili M.;
Koivumaa-Honkanen, Heli;
Hintikka, Jukka;
Niskanen, Leo;
Valkonen-Korhonen, Minna;
Viinamäki, Heimo

Publication type:

Article

Symptoms of Depression and Alexithymic Burden in Middle-Aged Men.

Published in:

Psychotherapy & Psychosomatics, 2010, v. 79, n. 4, p. 259, doi. 10.1159/000315132

By:

Kirsi Honkalampi;
Soili M. Lehto;
Jukka Hintikka;
Heli Koivumaa-Honkanen;
Leo Niskanen;
Heimo ViinamÃ¤ki

Publication type:

Article

Psychotherapy in Patients with Poorly Controlled Type 1 (Insulin-Dependent) Diabetes.

Published in:

Psychotherapy & Psychosomatics, 1991, v. 56, n. 1/2, p. 24, doi. 10.1159/000288526

By:

Viinamäki, Heimo;
Niskanen, Leo

Publication type:

Article

Physical Activity in the Prevention of Type 2 Diabetes.

Published in:

Diabetes, 2005, v. 54, n. 1, p. 158

By:

Laaksonen, David E.;
Lindström, Jaana;
Lakka, Timo A.;
Eriksson, Johan G.;
Niskanen, Leo;
Wikström, Katja;
Aunola, Sirkka;
Keinänen-Kiukaanniemi, Sirkka;
Laakso, Mauri;
Valle, Timo T.;
Ilanne-Parikka, Pirjo;
Louheranta, Anne;
Hämäläinen, Helena;
Rastas, Merja;
Salminen, Virpi;
Cepaitis, Zygimantas;
Hakumäki, Martti;
Kaikkonen, Hannu;
Härkönen, Pirjo;
Sundvall, Jouko

Publication type:

Article

Power spectral analysis of heart rate variability during hyperinsulinemia in nondiabetic offspring of type 2 diabetic patients: evidence for possible early autonomic dysfunction in insulin-resistant subjects.

Published in:

1999

By:

Laitinen, Tomi;
Vauhkonen, Ilkka K.J.;
Niskanen, Leo K.;
Hartikainen, Juha E.K.;
Lamsimies, Esko A.;
Uusitupa, Matti I.J.;
Laakso, Markku;
Laitinen, T;
Vauhkonen, I K;
Niskanen, L K;
Hartikainen, J E;
Länsimies, E A;
Uusitupa, M I;
Laakso, M

Publication type:

journal article

Occurrence, Predictors, and Clinical Significance of Autonomic Neuropathy in NIDDM.

Published in:

Diabetes, 1996, v. 45, n. 3, p. 308, doi. 10.2337/diab.45.3.308

By:

Töyry, Jari P.;
Niskanen, Leo K.;
Mäntysaari, Matti J.;
Länsimies, Esko A.;
Uusitupa, Matti I. J.

Publication type:

Article

Markers of absorption and synthesis of cholesterol in men with type 1 diabetes.

Published in:

Diabetes/Metabolism Research & Reviews, 2007, v. 23, n. 5, p. 372, doi. 10.1002/dmrr.697

By:

Gylling, Helena;
Laaksonen, David E.;
Atalay, Mustafa;
Hallikainen, Maarit;
Niskanen, Leo;
Miettinen, Tatu A.

Publication type:

Article

Increased cancer incidence in acromegaly – a nationwide survey.

Published in:

Clinical Endocrinology, 2010, v. 72, n. 2, p. 278, doi. 10.1111/j.1365-2265.2009.03619.x

By:

Kauppinen-Mäkelin, Ritva;
Sane, Timo;
Välimäki, Matti J.;
Markkanen, Helene;
Niskanen, Leo;
Ebeling, Tapani;
Jaatinen, Pia;
Juonala, Markus

Publication type:

Article

Cultured Allogeneic Skin Cells are Effective in the Treatment of Chronic Diabetic Leg and Foot Ulcers.

Published in:

Acta Dermato-Venereologica, 1999, v. 79, n. 3, p. 217, doi. 10.1080/000155599750011011

By:

Harvima, Ilkka T.;
Virnes, Suoma;
Kauppinen, Leena;
Huttunen, Maria;
Kivinen, Petri;
Niskanen, Leo;
Horsmanheimo, Maija

Publication type:

Article

Salivary matrix metalloproteinase (MMP-8) levels and gelatinase (MMP-9) activities in patients with type 2 diabetes mellitus.

Published in:

Journal of Periodontal Research, 2000, v. 35, n. 5, p. 259, doi. 10.1034/j.1600-0765.2000.035005259.x

By:

Coltin, Hannas-Leena;
Sorsa, Timo;
Meurman, Jukka H.;
Niskanen, Leo;
Saio, Tuula;
Ränkã, Hanne;
Konttinen, Yrjö T.;
Koivisto, Anna-Maija;
Uusitupa, Matti

Publication type:

Article

Trends in clinical characteristics, medication use, and glycemic control in insulin‐treated patients with type 1 and type 2 diabetes in Finland in 2012–2019: Nationwide real‐world evidence study.

Published in:

Journal of Diabetes, 2024, v. 16, n. 5, p. 1, doi. 10.1111/1753-0407.13491

By:

Niskanen, Leo;
Hannula, Minna;
Kysenius, Kai;
Kaijala, Saara;
Lassenius, Mariann I.;
Valle, Timo T.

Publication type:

Article

Lower rates of hypoglycemia during maintenance treatment with insulin degludec/insulin aspart versus biphasic insulin aspart 30: a combined analysis of two Phase 3a studies in type 2 diabetes.

Published in:

Journal of Diabetes, 2016, v. 8, n. 5, p. 720, doi. 10.1111/1753-0407.12355

By:

Christiansen, Jens Sandahl;
Niskanen, Leo;
Rasmussen, Søren;
Johansen, Thue;
Fulcher, Greg

Publication type:

Article

Depression and Associated Factors in Coronary Heart Disease.

Published in:

Scandinavian Cardiovascular Journal, 2001, v. 35, n. 4, p. 259, doi. 10.1080/14017430152581378

By:

Valkamo, Mari;
Hintikka, Jukka;
Niskanen, Leo;
Koivumaa-Honkanen, Heli;
Honkalampi, Kirsi;
Viinamäki, Heimo

Publication type:

Article

Excess mortality in Finnish diabetic subjects due to alcohol, accidents and suicide: a nationwide study.

Published in:

European Journal of Endocrinology, 2018, v. 179, n. 5, p. 299, doi. 10.1530/EJE-18-0351

By:

Niskanen, Leo;
Partonen, Timo;
Auvinen, Anssi;
Haukka, Jari

Publication type:

Article

Comparison of a soluble co-formulation of insulin degludec/insulin aspart vs biphasic insulin aspart 30 in type 2 diabetes: a randomised trial.

Published in:

2012

By:

Niskanen, Leo;
Leiter, Lawrence A.;
Franek, Edward;
Weng, Jianping;
Damci, Taner;
Muñoz-Torres, Manuel;
Donnet, Jean-Paul;
Endahl, Lars;
Skjøth, Trine Vang;
Vaag, Allan

Publication type:

Correction Notice

Comparison of a soluble co-formulation of insulin degludec/insulin aspart vs biphasic insulin aspart 30 in type 2 diabetes: a randomised trial.

Published in:

European Journal of Endocrinology, 2012, v. 167, n. 2, p. 287, doi. 10.1530/EJE-12-0293

By:

Niskanen, Leo;
Leiter, Lawrence A.;
Franek, Edward;
Jianping Weng;
Damci, Taner;
Muñoz-Torres, Manuel;
Donnet, Jean-Paul;
Endahl, Lars;
Skjøth, Trine Vang;
Vaag, Allan

Publication type:

Article

Sex hormones, inflammation and the metabolic syndrome: a population-based study.

Published in:

European Journal of Endocrinology, 2003, v. 149, n. 6, p. 0601

By:

David E Laaksonen;
Leo Niskanen;
Kari Punnonen;
Kristiina Nyyssonen;
Tomi-Pekka Tuomainen;
Riitta Salonen;
Rainer Rauramaa;
Jukka T Salonen

Publication type:

Article

Low levels of leisure-time physical activity and cardiorespiratory fitness predict development of the metabolic syndrome.

Published in:

2002

By:

Laaksonen, David E.;
Lakka, Hanna-Maaria;
Salonen, Jukka T.;
Niskanen, Leo K.;
Rauramaa, Rainer;
Lakka, Timo A.

Publication type:

journal article

ACE Inhibitor as One of Several Possible First-Line Agents Is Reasonable for Diabetic Patients With Hypertension.

Published in:

Diabetes Care, 2002, v. 25, n. 8, p. 1488, doi. 10.2337/diacare.25.8.1488-a

By:

Niskanen, Leo;
Hedner, Thomas;
Hansson, Lennart;
Lanke, Jan;
Niklason, Anders

Publication type:

Article

Carriers of an inactivating beta-cell ATP-sensitive K(+) channel mutation have normal glucose tolerance and insulin sensitivity and appropriate insulin secretion.

Published in:

2002

By:

Huopio, Hanna;
Vauhkonen, Ilkka;
Komulainen, Jorma;
Niskanen, Leo;
Otonkoski, Timo;
Laakso, Markku

Publication type:

journal article

Reduced cardiovascular morbidity and mortality in hypertensive diabetic patients on first-line therapy with an ACE inhibitor compared with a diuretic/beta-blocker-based treatment regimen: a subanalysis of the Captopril Prevention Project.

Published in:

2001

By:

Niskanen, Leo;
Hedner, Thomas;
Hansson, Lennart;
Lanke, Jan;
Niklason, Anders;
Niskanen, L;
Hedner, T;
Hansson, L;
Lanke, J;
Niklason, A;
CAPPP Study Group

Publication type:

journal article

Age-Related Macular Degeneration in Newly Diagnosed Type 2 Diabetic Patients and Control Subjects.

Published in:

Diabetes Care, 2000, v. 23, n. 11, p. 1672, doi. 10.2337/diacare.23.11.1672

By:

Voutilainen-Kaunisto, Raija M.;
Terasvirta, Markku E.;
Uusitupa, Matti I. J.;
Niskanen, Leo K.

Publication type:

Article

Variants in the Hepatocyte Nuclear Factor-1 alpha and -4 alpha Genes in Finnish and Chinese Subjects With Late-Onset Type 2 Diabetes.

Published in:

Diabetes Care, 2000, v. 23, n. 10, p. 1533, doi. 10.2337/diacare.23.10.1533

By:

Rissanen, Johanna;
Wang, Hua;
Miettinen, Raija;
Karkkainen, Paivi;
Kekalainen, Paivi;
Mykkanen, Leena;
Kuusisto, Johanna;
Karhapaa, Pauli;
Niskanen, Leo;
Uusitupa, Matti;
Laakso, Markku

Publication type:

Article

Sulfonylurea receptor 1 gene variants are associated with gestational diabetes and type 2 diabetes but not with altered secretion of insulin.

Published in:

2000

By:

Rissanen, Johanna;
Markkanen, Anu;
Kärkkäinen, Päivi;
Pihlajamäki, Jussi;
Kekäläinen, Päivi;
Mykkänen, Leena;
Kuusisto, Johanna;
Karhapää, Pauli;
Niskanen, Leo;
Laakso, Markku;
Rissanen, J;
Markkanen, A;
Kärkkäinen, P;
Pihlajamäki, J;
Kekäläinen, P;
Mykkänen, L;
Kuusisto, J;
Karhapää, P;
Niskanen, L;
Laakso, M

Publication type:

journal article

Hyperglycemia and compositional lipoprotein abnormalities as predictors of cardiovascular mortality in type 2 diabetes: a 15-year follow-up from the time of diagnosis.

Published in:

1998

By:

Niskanen, Leo;
Turpeinen, Anu;
Penttilä, Ilkka;
Uusitupa, Matti I.J.;
Niskanen, L;
Turpeinen, A;
Penttilä, I;
Uusitupa, M I

Publication type:

journal article

Increased Resting and Exercise-Induced Oxidative Stress in Young IDDM Men.

Published in:

Diabetes Care, 1996, v. 19, n. 6, p. 569, doi. 10.2337/diacare.19.6.569

By:

Laaksonen, David E.;
Atalay, Mustafa;
Niskanen, Leo;
Uusitupa, Matti;
Hånninen, Osmo;
Sen, Chandan K.

Publication type:

Article

Evolution, Risk Factors, and Prognostic Implications of Albuminuria in NIDDM.

Published in:

Diabetes Care, 1996, v. 19, n. 5, p. 486, doi. 10.2337/diacare.19.5.486

By:

Niskanen, Leo K.;
Penttilä, Ilkka;
Parviainen, Markku;
Uusitupa, Matti I. J.

Publication type:

Article

GAD Antibodies in NIDDM.

Published in:

Diabetes Care, 1995, v. 18, n. 12, p. 1557, doi. 10.2337/diacare.18.12.1557

By:

Niskanen, Leo K.;
Tuomi, Tiinamaija;
Karjalainen, Jukka;
Groop, Leif C.;
Uusitupa, Matti I. J.

Publication type:

Article