Works by NIGI, LAURA

Results: 26

Serum Levels of miR-148a and miR-21-5p Are Increased in Type 1 Diabetic Patients and Correlated with Markers of Bone Strength and Metabolism.

Published in:

Non-Coding RNA, 2018, v. 4, n. 4, p. 1, doi. 10.3390/ncrna4040037

By:

Grieco, Giuseppina E.;
Cataldo, Dorica;
Ceccarelli, Elena;
Nigi, Laura;
Catalano, Giovanna;
Brusco, Noemi;
Mancarella, Francesca;
Ventriglia, Giuliana;
Fondelli, Cecilia;
Guarino, Elisa;
Crisci, Isabella;
Sebastiani, Guido;
Dotta, Francesco

Publication type:

Article

Circulating microRNAs Signature for Predicting Response to GLP1-RA Therapy in Type 2 Diabetic Patients: A Pilot Study.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9454, doi. 10.3390/ijms22179454

By:

Formichi, Caterina;
Fignani, Daniela;
Nigi, Laura;
Grieco, Giuseppina Emanuela;
Brusco, Noemi;
Licata, Giada;
Sabato, Claudia;
Ferretti, Elisabetta;
Sebastiani, Guido;
Dotta, Francesco

Publication type:

Article

Non-Coding RNAs: Novel Players in Insulin Resistance and Related Diseases.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 14, p. 7716, doi. 10.3390/ijms22147716

By:

Formichi, Caterina;
Nigi, Laura;
Grieco, Giuseppina Emanuela;
Maccora, Carla;
Fignani, Daniela;
Brusco, Noemi;
Licata, Giada;
Sebastiani, Guido;
Dotta, Francesco

Publication type:

Article

The Landscape of microRNAs in βCell: Between Phenotype Maintenance and Protection.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 2, p. 803, doi. 10.3390/ijms22020803

By:

Grieco, Giuseppina Emanuela;
Brusco, Noemi;
Licata, Giada;
Fignani, Daniela;
Formichi, Caterina;
Nigi, Laura;
Sebastiani, Guido;
Dotta, Francesco

Publication type:

Article

MicroRNA Expression in the Aqueous Humor of Patients with Diabetic Macular Edema.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7328, doi. 10.3390/ijms21197328

By:

Grieco, Giuseppina Emanuela;
Sebastiani, Guido;
Eandi, Chiara Maria;
Neri, Giovanni;
Nigi, Laura;
Brusco, Noemi;
D'Aurizio, Romina;
Posarelli, Matteo;
Bacci, Tommaso;
De Benedetto, Elena;
Fruschelli, Mario;
Orlandini, Maurizio;
Galvagni, Federico;
Dotta, Francesco;
Tosi, Gian Marco

Publication type:

Article

Targeting microRNAs as a Therapeutic Strategy to Reduce Oxidative Stress in Diabetes.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 24, p. 6358, doi. 10.3390/ijms20246358

By:

Grieco, Giuseppina Emanuela;
Brusco, Noemi;
Licata, Giada;
Nigi, Laura;
Formichi, Caterina;
Dotta, Francesco;
Sebastiani, Guido

Publication type:

Article

MicroRNAs as Regulators of Insulin Signaling: Research Updates and Potential Therapeutic Perspectives in Type 2 Diabetes.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 12, p. 3705, doi. 10.3390/ijms19123705

By:

Nigi, Laura;
Grieco, Giuseppina Emanuela;
Ventriglia, Giuliana;
Brusco, Noemi;
Mancarella, Francesca;
Formichi, Caterina;
Dotta, Francesco;
Sebastiani, Guido

Publication type:

Article

12-Month Time in Tight Range Improvement with Advanced Hybrid-Closed Loop System in Adults with Type 1 Diabetes.

Published in:

Diabetes Therapy, 2024, v. 15, n. 12, p. 2557, doi. 10.1007/s13300-024-01656-w

By:

Nigi, Laura;
Simon Batzibal, Maria De Los Angeles;
Cataldo, Dorica;
Dotta, Francesco

Publication type:

Article

From immunohistological to anatomical alterations of human pancreas in type 1 diabetes: New concepts on the stage.

Published in:

2020

By:

Nigi, Laura;
Maccora, Carla;
Dotta, Francesco;
Sebastiani, Guido

Publication type:

journal article

MicroRNA expression profiles of human iPSCs differentiation into insulin-producing cells.

Published in:

Acta Diabetologica, 2017, v. 54, n. 3, p. 265, doi. 10.1007/s00592-016-0955-9

By:

Sebastiani, Guido;
Valentini, Marco;
Grieco, Giuseppina;
Ventriglia, Giuliana;
Nigi, Laura;
Mancarella, Francesca;
Pellegrini, Silvia;
Martino, Gianvito;
Sordi, Valeria;
Piemonti, Lorenzo;
Dotta, Francesco

Publication type:

Article

Comprehensive sequencing profile and functional analysis of IsomiRs in human pancreatic islets and beta cells.

Published in:

Diabetologia, 2025, v. 68, n. 6, p. 1261, doi. 10.1007/s00125-025-06397-4

By:

Auddino, Stefano;
Aiello, Elena;
Grieco, Giuseppina E.;
Fignani, Daniela;
Licata, Giada;
Bruttini, Marco;
Mori, Alessia;
Berteramo, Andrea F.;
Pedace, Erika;
Nigi, Laura;
Formichi, Caterina;
Guay, Claudiane;
Quero, Giuseppe;
Tondolo, Vincenzo;
Di Giuseppe, Gianfranco;
Soldovieri, Laura;
Ciccarelli, Gea;
Mari, Andrea;
Giaccari, Andrea;
Mezza, Teresa

Publication type:

Article

Intra-islet insulin synthesis defects are associated with endoplasmic reticulum stress and loss of beta cell identity in human diabetes.

Published in:

Diabetologia, 2023, v. 66, n. 2, p. 354, doi. 10.1007/s00125-022-05814-2

By:

Brusco, Noemi;
Sebastiani, Guido;
Di Giuseppe, Gianfranco;
Licata, Giada;
Grieco, Giuseppina E.;
Fignani, Daniela;
Nigi, Laura;
Formichi, Caterina;
Aiello, Elena;
Auddino, Stefano;
Quero, Giuseppe;
Cefalo, Chiara M. A.;
Cinti, Francesca;
Mari, Andrea;
Ferraro, Pietro M.;
Pontecorvi, Alfredo;
Alfieri, Sergio;
Giaccari, Andrea;
Dotta, Francesco;
Mezza, Teresa

Publication type:

Article

Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells.

Published in:

Diabetologia, 2018, v. 61, n. 11, p. 2344, doi. 10.1007/s00125-018-4704-1

By:

Ifie, Eseoghene;
Russell, Mark A.;
Dhayal, Shalinee;
Leete, Pia;
Sebastiani, Guido;
Nigi, Laura;
Dotta, Francesco;
Marjomäki, Varpu;
Eizirik, Decio L.;
Morgan, Noel G.;
Richardson, Sarah J.

Publication type:

Article

Reduced miR-184-3p expression protects pancreatic β-cells from lipotoxic and proinflammatory apoptosis in type 2 diabetes via CRTC1 upregulation.

Published in:

Cell Death Discovery, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41420-022-01142-x

By:

Grieco, Giuseppina E.;
Brusco, Noemi;
Fignani, Daniela;
Nigi, Laura;
Formichi, Caterina;
Licata, Giada;
Marselli, Lorella;
Marchetti, Piero;
Salvini, Laura;
Tinti, Laura;
Po, Agnese;
Ferretti, Elisabetta;
Sebastiani, Guido;
Dotta, Francesco

Publication type:

Article

Neutrophils in Type 1 Diabetes: Untangling the Intricate Web of Pathways and Hypothesis.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 4, p. 505, doi. 10.3390/biom15040505

By:

Nigi, Laura;
Pedace, Erika;
Dotta, Francesco;
Sebastiani, Guido

Publication type:

Article

SARS-CoV-2 Receptor Angiotensin I-Converting Enzyme Type 2 (ACE2) Is Expressed in Human Pancreatic β -Cells and in the Human Pancreas Microvasculature.

Published in:

Frontiers in Endocrinology, 2020, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.596898

By:

Fignani, Daniela;
Licata, Giada;
Brusco, Noemi;
Nigi, Laura;
Grieco, Giuseppina E.;
Marselli, Lorella;
Overbergh, Lut;
Gysemans, Conny;
Colli, Maikel L.;
Marchetti, Piero;
Mathieu, Chantal;
Eizirik, Decio L.;
Sebastiani, Guido;
Dotta, Francesco

Publication type:

Article

Pancreatic Alpha-Cells Contribute Together With Beta-Cells to CXCL10 Expression in Type 1 Diabetes.

Published in:

Frontiers in Endocrinology, 2020, v. 11, p. N.PAG, doi. 10.3389/fendo.2020.00630

By:

Nigi, Laura;
Brusco, Noemi;
Grieco, Giuseppina E.;
Licata, Giada;
Krogvold, Lars;
Marselli, Lorella;
Gysemans, Conny;
Overbergh, Lut;
Marchetti, Piero;
Mathieu, Chantal;
Dahl Jørgensen, Knut;
Sebastiani, Guido;
Dotta, Francesco

Publication type:

Article

Towards an Earlier and Timely Diagnosis of Type 1 Diabetes: Is it Time to Change Criteria to Define Disease Onset?

Published in:

2015

By:

Battaglia, Manuela;
Nigi, Laura;
Dotta, Francesco

Publication type:

journal article

Extracellular Vesicles in Immune System Regulation and Type 1 Diabetes: Cell-to-Cell Communication Mediators, Disease Biomarkers, and Promising Therapeutic Tools.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.682948

By:

Grieco, Giuseppina Emanuela;
Fignani, Daniela;
Formichi, Caterina;
Nigi, Laura;
Licata, Giada;
Maccora, Carla;
Brusco, Noemi;
Sebastiani, Guido;
Dotta, Francesco

Publication type:

Article

Islet-reactive CD8<sup>+</sup> T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors.

Published in:

Science Immunology, 2018, v. 3, n. 20, p. 1, doi. 10.1126/sciimmunol.aao4013

By:

Culina, Slobodan;
Lalanne, Ana Ines;
Afonso, Georgia;
Cerosaletti, Karen;
Pinto, Sheena;
Sebastiani, Guido;
Kuranda, Klaudia;
Nigi, Laura;
Eugster, Anne;
Østerbye, Thomas;
Maugein, Alicia;
McLaren, James E.;
Ladell, Kristin;
Larger, Etienne;
Beressi, Jean-Paul;
Lissina, Anna;
Appay, Victor;
Davidson, Howard W.;
Buus, Søren;
Price, David A.

Publication type:

Article

MicroRNAs: Novel Players in the Dialogue between Pancreatic Islets and Immune System in Autoimmune Diabetes.

Published in:

BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/749734

By:

Ventriglia, Giuliana;
Nigi, Laura;
Sebastiani, Guido;
Dotta, Francesco

Publication type:

Article

Prospective Validation of ATA and ETA Sonographic Pattern Risk of Thyroid Nodules Selected for FNAC.

Published in:

2018

By:

Maino, Fabio;
Forleo, Raffaella;
Martinelli, Martina;
Fralassi, Noemi;
Barbato, Filomena;
Pilli, Tania;
Capezzone, Marco;
Brilli, Lucia;
Ciuoli, Cristina;
Di Cairano, Giovanni;
Nigi, Laura;
Pacini, Furio;
Castagna, Maria Grazia

Publication type:

journal article

CD8<sup>+</sup> T Cells Variably Recognize Native Versus Citrullinated GRP78 Epitopes in Type 1 Diabetes.

Published in:

2021

By:

Azoury, Marie Eliane;
Samassa, Fatoumata;
Buitinga, Mijke;
Nigi, Laura;
Brusco, Noemi;
Callebaut, Aïsha;
Giraud, Matthieu;
Irla, Magali;
Lalanne, Ana Ines;
Carré, Alexia;
Afonso, Georgia;
Zhou, Zhicheng;
Brandao, Barbara;
Colli, Maikel L.;
Sebastiani, Guido;
Dotta, Francesco;
Nakayama, Maki;
Eizirik, Decio L.;
You, Sylvaine;
Pinto, Sheena

Publication type:

journal article

290-OR: Altered In-Situ Expression of Proinsulin-Insulin in Pancreatic Islets Reflects Metabolic and Molecular Defects in Type 2 Diabetic and Glucose-Intolerant Living Donors.

Published in:

Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-290-OR

By:

BRUSCO, NOEMI;
SEBASTIANI, GUIDO;
LICATA, GIADA;
GRIECO, GIUSEPPINA E.;
GIUSEPPE, GIANFRANCO DI;
NIGI, LAURA;
FIGNANI, DANIELA;
MOFFA, SIMONA;
CINTI, FRANCESCA;
CEFALO, CHIARA MARIA ASSUNTA;
CAPECE, UMBERTO;
IMPRONTA, FLAVIA;
MARI, ANDREA;
DOTTA, FRANCESCO;
GIACCARI, ANDREA;
MEZZA, TERESA

Publication type:

Article

1795-P: Proinsulin-Insulin Pancreatic Islets In-situ Expression Mirrors Metabolic Defects Observed in Type 2 Diabetic and Glucose Intolerant Living Donors.

Published in:

Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1795-P

By:

BRUSCO, NOEMI;
SEBASTIANI, GUIDO;
LICATA, GIADA;
GRIECO, GIUSEPPINA E.;
NIGI, LAURA;
FIGNANI, DANIELA;
MOFFA, SIMONA;
SORICE, GIAN PIO;
DI GIUSEPPE, GIANFRANCO;
ASSUNTA CEFALO JR., CHIARA MARIA;
MARI, ANDREA;
DOTTA, FRANCESCO;
GIACCARI, ANDREA;
MEZZA, TERESA

Publication type:

Article

Increased Expression of Viral Sensor MDA5 in Pancreatic Islets and in Hormone-Negative Endocrine Cells in Recent Onset Type 1 Diabetic Donors.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.833141

By:

Nigi, Laura;
Brusco, Noemi;
Grieco, Giuseppina E.;
Fignani, Daniela;
Licata, Giada;
Formichi, Caterina;
Aiello, Elena;
Marselli, Lorella;
Marchetti, Piero;
Krogvold, Lars;
Jorgensen, Knut Dahl;
Sebastiani, Guido;
Dotta, Francesco

Publication type:

Article