Works by Mykkänen, Juha

Results: 33

Association of leisure time physical activity with gut microbiota composition in early adulthood.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-02287-2

By:

Boelius, Hanna-Mari;
Aatsinki, Anna-Katariina;
Heiskanen, Marja A.;
Haapala, Eero A.;
Munukka, Eveliina;
Mykkänen, Juha;
Kartiosuo, Noora;
Lahti, Leo;
Keskitalo, Anniina;
Huovinen, Pentti;
Niinikoski, Harri;
Viikari, Jorma;
Rönnemaa, Tapani;
Lagström, Hanna;
Jula, Antti;
Rovio, Suvi P.;
Raitakari, Olli T.;
Pahkala, Katja

Publication type:

Article

Association of leisure time physical activity with gut microbiota composition in early adulthood.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-02287-2

By:

Boelius, Hanna-Mari;
Aatsinki, Anna-Katariina;
Heiskanen, Marja A.;
Haapala, Eero A.;
Munukka, Eveliina;
Mykkänen, Juha;
Kartiosuo, Noora;
Lahti, Leo;
Keskitalo, Anniina;
Huovinen, Pentti;
Niinikoski, Harri;
Viikari, Jorma;
Rönnemaa, Tapani;
Lagström, Hanna;
Jula, Antti;
Rovio, Suvi P.;
Raitakari, Olli T.;
Pahkala, Katja

Publication type:

Article

Childhood exposure to parental smoking and life-course overweight and central obesity.

Published in:

Annals of Medicine, 2021, v. 53, n. 1, p. 208, doi. 10.1080/07853890.2020.1853215

By:

Jaakkola, Johanna M.;
Rovio, Suvi P.;
Pahkala, Katja;
Viikari, Jorma;
Rönnemaa, Tapani;
Jula, Antti;
Niinikoski, Harri;
Mykkänen, Juha;
Juonala, Markus;
Hutri-Kähönen, Nina;
Kähönen, Mika;
Lehtimäki, Terho;
Raitakari, Olli T.

Publication type:

Article

Childhood exposure to parental smoking and life-course overweight and central obesity.

Published in:

Annals of Medicine, 2021, v. 53, n. 1, p. 208, doi. 10.1080/07853890.2020.1853215

By:

Jaakkola, Johanna M.;
Rovio, Suvi P.;
Pahkala, Katja;
Viikari, Jorma;
Rönnemaa, Tapani;
Jula, Antti;
Niinikoski, Harri;
Mykkänen, Juha;
Juonala, Markus;
Hutri-Kähönen, Nina;
Kähönen, Mika;
Lehtimäki, Terho;
Raitakari, Olli T.

Publication type:

Article

Exploring machine learning strategies for predicting cardiovascular disease risk factors from multi-omic data.

Published in:

BMC Medical Informatics & Decision Making, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12911-024-02521-3

By:

Drouard, Gabin;
Mykkänen, Juha;
Heiskanen, Jarkko;
Pohjonen, Joona;
Ruohonen, Saku;
Pahkala, Katja;
Lehtimäki, Terho;
Wang, Xiaoling;
Ollikainen, Miina;
Ripatti, Samuli;
Pirinen, Matti;
Raitakari, Olli;
Kaprio, Jaakko

Publication type:

Article

Association of Human Bocavirus 1 Infection with Respiratory Disease in Childhood Follow-up Study, Finland.

Published in:

Emerging Infectious Diseases, 2012, v. 18, n. 2, p. 264, doi. 10.3201/eid1802.111293

By:

Meriluoto, Mira;
Hedman, Lea;
Tanner, Laura;
Simell, Ville;
Mäkinen, Marjaana;
Simell, Satu;
Mykkänen, Juha;
Korpelainen, Jan;
Ruuskanen, Olli;
Ilonen, Jorma;
Knip, Mikael;
Simell, Olli;
Hedman, Klaus;
Söderlund-Venermo, María

Publication type:

Article

Genetic homogeneity of lysinuric protein intolerance.

Published in:

European Journal of Human Genetics, 1998, v. 6, n. 6, p. 612, doi. 10.1038/sj.ejhg.5200236

By:

Lauteala, Tuija;
Mykkänen, Juha;
Sperandeo, Maria Pia;
Gasparini, Paolo;
Savontaus, Marja-Liisa;
Simell, Olli;
Andria, Generoso;
Sebastio, Gianfranco;
Aula, Pentti

Publication type:

Article

Blood pressure in childhood, young- and mid-adulthood: association with carotid plaque severity.

Published in:

European Heart Journal, 2025, v. 46, n. 24, p. 2306, doi. 10.1093/eurheartj/ehaf139

By:

Meng, Yaxing;
Koskinen, Juhani S;
Thomson, Russell;
Juonala, Markus;
Pahkala, Katja;
Mykkänen, Juha;
Rovio, Suvi P;
Kähönen, Mika;
Lehtimäki, Terho;
Viikari, Jorma S A;
Raitakari, Olli T;
Magnussen, Costan G

Publication type:

Article

Randomized 20-year infancy-onset dietary intervention, life-long cardiovascular risk factors and retinal microvasculature.

Published in:

European Heart Journal, 2024, v. 45, n. 33, p. 3072, doi. 10.1093/eurheartj/ehae423

By:

Repo, Oskari;
Juonala, Markus;
Niinikoski, Harri;
Rovio, Suvi;
Mykkänen, Juha;
Lagström, Hanna;
Cheung, Carol Y;
Yang, Dawei;
Vaahtoranta-Lehtonen, Hanna;
Jula, Antti;
Nevalainen, Jaakko;
Rönnemaa, Tapani;
Viikari, Jorma;
Raitakari, Olli;
Tapp, Robyn;
Pahkala, Katja

Publication type:

Article

Identification of SLC7A7, encoding y<sup>+</sup>LAT-1, as the lysinuric protein intolerance gene.

Published in:

Nature Genetics, 1999, v. 21, n. 3, p. 293, doi. 10.1038/6809

By:

Torrents, David;
Mykkänen, Juha;
Pineda, Marta;
Feliubadaló, Lidia;
Estévez, Raúl;
Cid, Rafael de;
Sanjurjo, Pablo;
Zorzano, Antonio;
Nunes, Virginia;
Huoponen, Kirsi;
Reinikainen, Arja;
Simell, Olli;
Savontaus, Marja-Liisa;
Aula, Pertti;
Palacín, Manuel

Publication type:

Article

Type 1 Diabetes in Children With Genetic Risk May Be Predicted Very Early With a Blood miRNA.

Published in:

2022

By:

Suomi, Tomi;
Kalim, Ubaid Ullah;
Rasool, Omid;
Laiho, Asta;
Kallionpää, Henna;
Vähä-Mäkilä, Mari;
Nurmio, Mirja;
Mykkänen, Juha;
Härkőnen, Taina;
Hyőty, Heikki;
Ilonen, Jorma;
Veijola, Riitta;
Toppari, Jorma;
Knip, Mikael;
Elo, Laura L.;
Lahesmaa, Riitta;
Härkönen, Taina;
Hyöty, Heikki

Publication type:

Letter

Systematic Literature Review on Empirical Results and Practical Implementations of Healthcare Recommender Systems: Lessons Learned and a Novel Proposal.

Published in:

International Journal of Healthcare Information Systems & Informatics, 2015, v. 10, n. 4, p. 1, doi. 10.4018/IJHISI.2015100101

By:

Afolabi, Adekunle Oluseyi;
Toivanen, Pekka;
Haataja, Keijo;
Mykkänen, Juha

Publication type:

Article

Metabolic transition from childhood to adulthood based on two decades of biochemical time series in three longitudinal cohorts.

Published in:

International Journal of Epidemiology, 2025, v. 54, n. 2, p. 1, doi. 10.1093/ije/dyaf026

By:

Mäkinen, Ville-Petteri;
Kähönen, Mika;
Lehtimäki, Terho;
Hutri, Nina;
Rönnemaa, Tapani;
Viikari, Jorma;
Pahkala, Katja;
Rovio, Suvi;
Niinikoski, Harri;
Mykkänen, Juha;
Raitakari, Olli;
Ala-Korpela, Mika

Publication type:

Article

Evaluating the direct effects of childhood adiposity on adult systemic metabolism: a multivariable Mendelian randomization analysis.

Published in:

2021

By:

Richardson, Tom G;
Mykkänen, Juha;
Pahkala, Katja;
Ala-Korpela, Mika;
Bell, Joshua A;
Taylor, Kurt;
Viikari, Jorma;
Lehtimäki, Terho;
Raitakari, Olli;
Smith, George Davey;
Davey Smith, George

Publication type:

journal article

Functional analysis of novel mutations in y[sup +]LAT-1 amino acid transporter gene causing lysinuric protein intolerance (LPI).

Published in:

Human Molecular Genetics, 2000, v. 9, n. 3, p. 431, doi. 10.1093/hmg/9.3.431

By:

Mykkänen, Juha

Publication type:

Article

Glycoprotein Acetyls: A Novel Inflammatory Biomarker of Early Cardiovascular Risk in the Young.

Published in:

2022

By:

Chiesa, Scott T.;
Charakida, Marietta;
Georgiopoulos, Georgios;
Roberts, Justin D.;
Stafford, Simon J.;
Park, Chloe;
Mykkänen, Juha;
Kähönen, Mika;
Lehtimäki, Terho;
Korpela, Mika Ala;
Raitakari, Olli;
Pietiäinen, Milla;
Pussinen, Pirkko;
Muthurangu, Vivek;
Hughes, Alun D.;
Sattar, Naveed;
Timpson, Nicholas J.;
Deanfield, John E.;
Ala-Korpela, Mika

Publication type:

journal article

Bacteroides dorei dominates gut microbiome prior to autoimmunity in Finnish children at high risk for type 1 diabetes.

Published in:

Frontiers in Microbiology, 2014, v. 5, p. 1, doi. 10.3389/fmicb.2014.00678

By:

Davis-Richardson, Austin G.;
Ardissone, Alexandria N.;
Dias, Raquel;
Simell, Ville;
Leonard, Michael T.;
Kemppainen, Kaisa M.;
Drew, Jennifer C.;
Schatz, Desmond;
Atkinson, Mark A.;
Kolaczkowski, Bryan;
Ilonen, Jorma;
Knip, Mikael;
Toppari, Jorma;
Nurminen, Noora;
Hyöty, Heikki;
Veijola, Riitta;
Simell, Tuula;
Mykkänen, Juha;
Simell, Olli;
Triplett, Eric W.

Publication type:

Article

Serum 25-Hydroxyvitamin D Concentrations in Children Progressing to Autoimmunity and Clinical Type 1 Diabetes.

Published in:

2016

By:

Mäkinen, Marjaana;
Mykkänen, Juha;
Koskinen, Maarit;
Simell, Ville;
Veijola, Riitta;
Hyöty, Heikki;
Ilonen, Jorma;
Knip, Mikael;
Simell, Olli;
Toppari, Jorma

Publication type:

journal article

An increase in serum 25-hydroxyvitamin D concentrations preceded a plateau in type 1 diabetes incidence in Finnish children.

Published in:

2014

By:

Mäkinen, Marjaana;
Simell, Ville;
Mykkänen, Juha;
Ilonen, Jorma;
Veijola, Riitta;
Hyöty, Heikki;
Knip, Mikael;
Simell, Olli;
Toppari, Jorma;
Hermann, Robert

Publication type:

journal article

Umbilical cord blood DNA methylation in children who later develop type 1 diabetes.

Published in:

Diabetologia, 2022, v. 65, n. 9, p. 1534, doi. 10.1007/s00125-022-05726-1

By:

Laajala, Essi;
Kalim, Ubaid Ullah;
Grönroos, Toni;
Rasool, Omid;
Halla-aho, Viivi;
Konki, Mikko;
Kattelus, Roosa;
Mykkänen, Juha;
Nurmio, Mirja;
Vähä-Mäkilä, Mari;
Kallionpää, Henna;
Lietzén, Niina;
Ghimire, Bishwa R.;
Laiho, Asta;
Hyöty, Heikki;
Elo, Laura L.;
Ilonen, Jorma;
Knip, Mikael;
Lund, Riikka J.;
Orešič, Matej

Publication type:

Article

Enterovirus-associated changes in blood transcriptomic profiles of children with genetic susceptibility to type 1 diabetes.

Published in:

Diabetologia, 2018, v. 61, n. 2, p. 381, doi. 10.1007/s00125-017-4460-7

By:

Lietzen, Niina;
An, Le T. T.;
Jaakkola, Maria K.;
Kallionpää, Henna;
Oikarinen, Sami;
Mykkänen, Juha;
Knip, Mikael;
Veijola, Riitta;
Ilonen, Jorma;
Toppari, Jorma;
Hyöty, Heikki;
Lahesmaa, Riitta;
Elo, Laura L.

Publication type:

Article

Reduced β-cell function in early preclinical type 1 diabetes.

Published in:

European Journal of Endocrinology, 2016, v. 174, n. 3, p. 251, doi. 10.1530/EJE-15-0674

By:

Koskinen, Maarit K.;
Helminen, Olli;
Matomäki, Jaakko;
Aspholm, Susanna;
Mykkänen, Juha;
Makinen, Marjaana;
Simell, Ville;
Vähä-Mäkilä, Mari;
Simell, Tuula;
Ilonen, Jorma;
Knip, Mikael;
Veijola, Riitta;
Toppari, Jorma;
Simell, Olli

Publication type:

Article

Association of Serum Trimethylamine-N-Oxide Concentration from Childhood to Early Adulthood with Age and Sex.

Published in:

Clinical Chemistry, 2024, v. 70, n. 9, p. 1162, doi. 10.1093/clinchem/hvae087

By:

Almer, Gunter;
Enko, Dietmar;
Kartiosuo, Noora;
Niinikoski, Harri;
Lehtimäki, Terho;
Munukka, Eveliina;
Viikari, Jorma;
Rönnemaa, Tapani;
Rovio, Suvi P;
Mykkänen, Juha;
Lagström, Hanna;
Jula, Antti;
Herrmann, Markus;
Raitakari, Olli T;
Meinitzer, Andreas;
Pahkala, Katja

Publication type:

Article

Serum Proteomes Distinguish Children Developing Type 1 Diabetes in a Cohort With HLA-Conferred Susceptibility.

Published in:

Diabetes, 2015, v. 64, n. 6, p. 2265, doi. 10.2337/db14-0983

By:

Moulder, Robert;
Bhosale, Santosh D.;
Erkkilä, Timo;
Laajala, Essi;
Salmi, Jussi;
Nguyen, Elizabeth V.;
Kallionpää, Henna;
Mykkänen, Juha;
Vähä-Mäkilä, Mari;
Hyöty, Heikki;
Veijola, Riitta;
Ilonen, Jorma;
Simell, Tuula;
Toppari, Jorma;
Knip, Mikael;
Goodlett, David R.;
Lähdesmäki, Harri;
Simell, Olli;
Lahesmaa, Riitta

Publication type:

Article

Role of Type 1 Diabetes-Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study.

Published in:

Diabetes, 2015, v. 64, n. 5, p. 1818, doi. 10.2337/db14-1497

By:

Törn, Carina;
Hadley, David;
Hye-Seung Lee;
Hagopian, William;
Lernmark, Åke;
Simell, Olli;
Rewers, Marian;
Ziegler, Anette;
Schatz, Desmond;
Akolkar, Beena;
Onengut-Gumuscu, Suna;
Wei-Min Chen;
Toppari, Jorma;
Mykkänen, Juha;
Ilonen, Jorma;
Rich, Stephen S.;
Jin-Xiong She;
Steck, Andrea K.;
Krischer, Jeffrey

Publication type:

Article

Innate Immune Activity Is Detected Prior to Seroconversion in Children With HLA-Conferred Type 1 Diabetes Susceptibility.

Published in:

Diabetes, 2014, v. 63, n. 7, p. 2402, doi. 10.2337/db13-1775

By:

Kallionpää, Henna;
Elo, Laura L.;
Laajala, Essi;
Mykkänen, Juha;
Ricaño-Ponce, Isis;
Vaarma, Matti;
Laajala, Teemu D.;
Hyöty, Heikki;
Ilonen, Jorma;
Veijola, Riitta;
Simell, Tuula;
Wijmenga, Cisca;
Knip, Mikael;
Lähdesmäki, Harri;
Simell, Olli;
Lahesmaa, Riitta

Publication type:

Article

Cord Serum Lipidome in Prediction of Islet Autoimmunity and Type 1 Diabetes.

Published in:

Diabetes, 2013, v. 62, n. 9, p. 3268, doi. 10.2337/db13-0159

By:

Orešič, Matej;
Gopalacharyulu, Peddinti;
Mykkänen, Juha;
Lietzen, Niina;
Mäkinen, Marjaana;
Nygren, Heli;
Simell, Satu;
Simell, Ville;
Hyöty, Heikki;
Veijola, Riitta;
Ilonen, Jorma;
Sysi-Aho, Marko;
Knip, Mikael;
Hyötyläinen, Tuulia;
Simell, Olli

Publication type:

Article

Feasibility of prenatal diagnosis of lysinuric protein intolerance by linkage analysis: a case report.

Published in:

Prenatal Diagnosis, 1999, v. 19, n. 8, p. 771, doi. 10.1002/(SICI)1097-0223(199908)19:8<771::AID-PD612>3.0.CO;2-J

By:

Sperandeo, Maria Pia;
Buoninconti, Anna;
Passariello, Annalisa;
Scala, Iris;
Adami, Andrea;
Lauteala, Tuija;
Mykkänen, Juha;
Andria, Generoso;
Sebastio, Gianfranco

Publication type:

Article

Serum 25-Hydroxyvitamin D Concentrations at Birth in Children Screened for HLA-DQB1 Conferred Risk for Type 1 Diabetes.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2019, v. 104, n. 6, p. 2277, doi. 10.1210/jc.2018-02094

By:

Mäkinen, Marjaana;
Löyttyniemi, Eliisa;
Koskinen, Maarit;
Vähä-Mäkilä, Mari;
Siljander, Heli;
Nurmio, Mirja;
Mykkänen, Juha;
Virtanen, Suvi M.;
Simell, Olli;
Hyöty, Heikki;
Ilonen, Jorma;
Knip, Mikael;
Veijola, Riitta;
Toppari, Jorma

Publication type:

Article

Serum 25-Hydroxyvitamin D Concentrations at Birth in Children Screened for HLA-DQB1 Conferred Risk for Type 1 Diabetes.

Published in:

2019

By:

Mäkinen, Marjaana;
Löyttyniemi, Eliisa;
Koskinen, Maarit;
Vähä-Mäkilä, Mari;
Siljander, Heli;
Nurmio, Mirja;
Mykkänen, Juha;
Virtanen, Suvi M;
Simell, Olli;
Hyöty, Heikki;
Ilonen, Jorma;
Knip, Mikael;
Veijola, Riitta;
Toppari, Jorma

Publication type:

journal article

Systematic Literature Review on Empirical Results and Practical Implementations of Healthcare Recommender Systems: Lessons Learned and a Novel Proposal.

Published in:

Journal of Database Management, 2015, p. 1, doi. 10.4018/IJHISI.2015100101

By:

Afolabi, Adekunle Oluseyi;
Toivanen, Pekka;
Haataja, Keijo;
Mykkänen, Juha

Publication type:

Article

Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study.

Published in:

Scientific Reports, 2016, p. 27887, doi. 10.1038/srep27887

By:

Törn, Carina;
Liu, Xiang;
Hagopian, William;
Lernmark, Åke;
Simell, Olli;
Rewers, Marian;
Ziegler, Anette-G;
Schatz, Desmond;
Akolkar, Beena;
Onengut-Gumuscu, Suna;
Chen, Wei-Min;
Toppari, Jorma;
Mykkänen, Juha;
Ilonen, Jorma;
Rich, Stephen S.;
She, Jin-Xiong;
Sharma, Ashok;
Steck, Andrea;
Krischer, Jeffrey

Publication type:

Article

Permutation-based significance analysis reduces the type 1 error rate in bisulphite sequencing data analysis of human umbilical cord blood samples.

Published in:

Epigenetics, 2022, v. 17, n. 12, p. 1608, doi. 10.1080/15592294.2022.2044127

By:

Laajala, Essi;
Halla-aho, Viivi;
Grönroos, Toni;
Kalim, Ubaid Ullah;
Vähä-Mäkilä, Mari;
Nurmio, Mirja;
Kallionpää, Henna;
Lietzén, Niina;
Mykkänen, Juha;
Rasool, Omid;
Toppari, Jorma;
Orešič, Matej;
Knip, Mikael;
Lund, Riikka;
Lahesmaa, Riitta;
Lähdesmäki, Harri

Publication type:

Article