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Longitudinal Pharmacokinetic-Pharmacodynamic Biomarkers Correlate With Treatment Outcome in Drug-Sensitive Pulmonary Tuberculosis: A Population Pharmacokinetic-Pharmacodynamic Analysis.
Published in:
Open Forum Infectious Diseases, 2020, v. 7, n. 7, p. 1, doi. 10.1093/ofid/ofaa218
By:
- Kloprogge, Frank;
- Mwandumba, Henry C;
- Banda, Gertrude;
- Kamdolozi, Mercy;
- Shani, Doris;
- Corbett, Elizabeth L;
- Kontogianni, Nadia;
- Ward, Steve;
- Khoo, Saye H;
- Davies, Geraint R;
- Sloan, Derek J
Publication type:
Article
Intracellular survival of Streptococcus pneumoniae in human alveolar macrophages is augmented with HIV infection.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.992659
By:
- Nyazika, Tinashe K.;
- Sibale, Lusako;
- Phiri, Joseph;
- De Ste Croix, Megan;
- Jasiunaite, Zydrune;
- Mkandawire, Christopher;
- Malamba, Rose;
- Kankwatira, Anstead;
- Manduwa, Miriam;
- Ferreira, Daniela M.;
- Nyirenda, Tonney S.;
- Oggioni, Marco R.;
- Mwandumba, Henry C.;
- Jambo, Kondwani C.
Publication type:
Article
The significant gap between international standards and stroke management practices at Queen Elizabeth Central Hospital (Malawi): An audit report.
Published in:
Malawi Medical Journal, 2019, v. 31, n. 4, p. 249, doi. 10.4314/mmj.v31i4.6
By:
- Gadama, Yohane;
- Kamtchum-Tatuene, Joseph;
- Benjamin, Laura;
- Phiri, Tamara;
- Mwandumba, Henry C.
Publication type:
Article
Challenges of stroke management in resource-limited settings: A case-based reflection.
Published in:
Malawi Medical Journal, 2017, v. 29, n. 2, p. 189, doi. 10.4314/mmj.v29i2.21
By:
- Gadama, Yohane G.;
- Mwangalika, Gloria;
- Kinley, Louis B.;
- Jackson, Beth;
- Mwandumba, Henry C.;
- Mallewa, Jane;
- Solomon, Tom;
- Simister, Rob;
- Benjamin, Laura A.;
- Vargas, Maria I.;
- Kamtchum-Tatuene, Joseph;
- Phiri, Tamara
Publication type:
Article
Tuberculosis Immunoreactivity Surveillance in Malawi (Timasamala)—A protocol for a cross-sectional Mycobacterium tuberculosis immunoreactivity survey in Blantyre, Malawi.
Published in:
PLoS ONE, 2024, v. 19, n. 5, p. 1, doi. 10.1371/journal.pone.0291215
By:
- Rickman, Hannah M.;
- Phiri, Mphatso D.;
- Feasey, Helena R. A.;
- Mbale, Hannah;
- Nliwasa, Marriott;
- Semphere, Robina;
- Chagaluka, George;
- Fielding, Katherine;
- Mwandumba, Henry C.;
- Horton, Katherine C.;
- Nightingale, Emily S.;
- Henrion, Marc Y. R.;
- Mbendera, Kuzani;
- Mpunga, James A.;
- Corbett, Elizabeth L.;
- MacPherson, Peter
Publication type:
Article
Correction to: AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial.
Published in:
2019
By:
- Lawrence, David S.;
- Youssouf, Nabila;
- Molloy, Síle F.;
- Alanio, Alexandre;
- Alufandika, Melanie;
- Boulware, David R.;
- Boyer-Chammard, Timothée;
- Chen, Tao;
- Dromer, Francoise;
- Hlupeni, Admire;
- Hope, William;
- Hosseinipour, Mina C.;
- Kanyama, Cecilia;
- Lortholary, Oliver;
- Loyse, Angela;
- Meya, David B.;
- Mosepele, Mosepele;
- Muzoora, Conrad;
- Mwandumba, Henry C.;
- Ndhlovu, Chiratidzo E.
Publication type:
journal article
AMBIsome Therapy Induction OptimisatioN (AMBITION): High Dose AmBisome for Cryptococcal Meningitis Induction Therapy in sub-Saharan Africa: Study Protocol for a Phase 3 Randomised Controlled Non-Inferiority Trial.
Published in:
2018
By:
- Lawrence, David S.;
- Youssouf, Nabila;
- Molloy, Síle L. F.;
- Alanio, Alexandre;
- Alufandika, Melanie;
- Boulware, David R.;
- Boyer-Chammard, Timothée;
- Chen, Tao;
- Dromer, Francoise;
- Hlupeni, Admire;
- Hope, William;
- Hosseinipour, Mina C.;
- Kanyama, Cecilia;
- Lortholary, Oliver;
- Loyse, Angela;
- Meya, David B.;
- Mosepele, Mosepele;
- Muzoora, Conrad;
- Mwandumba, Henry C.;
- Ndhlovu, Chiratidzo E.
Publication type:
journal article
Mycobacterium and the coat of many lipids.
Published in:
Journal of Cell Biology, 2002, v. 158, n. 3, p. 421, doi. 10.1083/jcb.200205034
By:
- Russell, David G.;
- Mwandumba, Henry C.;
- Rhoades, Elizabeth E.
Publication type:
Article
Etiology and Risk Factors for Mortality in an Adult Community-acquired Pneumonia Cohort in Malawi.
Published in:
2019
By:
- Aston, Stephen J.;
- Ho, Antonia;
- Jary, Hannah;
- Huwa, Jacqueline;
- Mitchell, Tamara;
- Ibitoye, Sarah;
- Greenwood, Simon;
- Joekes, Elizabeth;
- Daire, Arthur;
- Mallewa, Jane;
- Everett, Dean;
- Nyirenda, Mulinda;
- Faragher, Brian;
- Mwandumba, Henry C.;
- Heyderman, Robert S.;
- Gordon, Stephen B.
Publication type:
journal article
Inflammatory pathways amongst people living with HIV in Malawi differ according to socioeconomic status.
Published in:
PLoS ONE, 2021, v. 16, n. 8, p. 1, doi. 10.1371/journal.pone.0256576
By:
- Kelly, Christine;
- Tinago, Willard;
- Alber, Dagmar;
- Hunter, Patricia;
- Luckhurst, Natasha;
- Connolly, Jake;
- Arrigoni, Francesca;
- Garcia Abner, Alejandro;
- Kamn'gona, Raphael;
- Sheha, Irene;
- Chammudzi, Mishek;
- Jambo, Kondwani;
- Mallewa, Jane;
- Rapala, Alicja;
- Mallon, Patrick W. G.;
- Mwandumba, Henry;
- Klein, Nigel;
- Khoo, Saye
Publication type:
Article
Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state.
Published in:
2018
By:
- Mitsi, Elena;
- Kamng'ona, Raphael;
- Rylance, Jamie;
- Solórzano, Carla;
- Jesus Reiné, J.;
- Mwandumba, Henry C.;
- Ferreira, Daniela M.;
- Jambo, Kondwani C.
Publication type:
Letter
The macrophage marches on its phagosome: dynamic assays of phagosome function.
Published in:
2009
By:
- Russell, David G.;
- VanderVen, Brian C.;
- Glennie, Sarah;
- Mwandumba, Henry;
- Heyderman, Robert S.
Publication type:
research
A cross-sectional feasibility study of neurovascular ultrasound in Malawian adults with acute stroke-like syndrome.
Published in:
PLoS ONE, 2020, v. 15, n. 2, p. 1, doi. 10.1371/journal.pone.0229033
By:
- Kamtchum-Tatuene, Joseph;
- Mwandumba, Henry C.;
- Mwangalika Kachingwe, Gloria;
- Bonnett, Laura J.;
- Kayange, Noel;
- Solomon, Tom;
- Benjamin, Laura A.
Publication type:
Article
Something Old, Something New: Ion Channel Blockers as Potential Anti-Tuberculosis Agents.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.665785
By:
- Mitini-Nkhoma, Steven C.;
- Chimbayo, Elizabeth T.;
- Mzinza, David T.;
- Mhango, David V.;
- Chirambo, Aaron P.;
- Mandalasi, Christine;
- Lakudzala, Agness E.;
- Tembo, Dumizulu L.;
- Jambo, Kondwani C.;
- Mwandumba, Henry C.
Publication type:
Article
Intrapulmonary Pharmacokinetics of First-line Anti-tuberculosis Drugs in Malawian Patients With Tuberculosis.
Published in:
Clinical Infectious Diseases, 2021, v. 73, n. 9, p. e3365, doi. 10.1093/cid/ciaa1265
By:
- McCallum, Andrew D;
- Pertinez, Henry E;
- Else, Laura J;
- Dilly-Penchala, Sujan;
- Chirambo, Aaron P;
- Sheha, Irene;
- Chasweka, Madalitso;
- Chitani, Alex;
- Malamba, Rose D;
- Meghji, Jamilah Z;
- Gordon, Stephen B;
- Davies, Geraint R;
- Khoo, Saye H;
- Sloan, Derek J;
- Mwandumba, Henry C
Publication type:
Article
Tuberculosis in Hospitalized Patients With Human Immunodeficiency Virus: Clinical Characteristics, Mortality, and Implications From the Rapid Urine-based Screening for Tuberculosis to Reduce AIDS Related Mortality in Hospitalized Patients in Africa.
Published in:
Clinical Infectious Diseases, 2020, v. 71, n. 10, p. 2618, doi. 10.1093/cid/ciz1133
By:
- Gupta-Wright, Ankur;
- Fielding, Katherine;
- Wilson, Douglas;
- Oosterhout, Joep J van;
- Grint, Daniel;
- Mwandumba, Henry C;
- Alufandika-Moyo, Melanie;
- Peters, Jurgens A;
- Chiume, Lingstone;
- Lawn, Stephen D;
- Corbett, Elizabeth L
Publication type:
Article
Inflammatory Phenotypes Predict Changes in Arterial Stiffness Following Antiretroviral Therapy Initiation.
Published in:
Clinical Infectious Diseases, 2020, v. 71, n. 9, p. 2389, doi. 10.1093/cid/ciaa186
By:
- Kelly, Christine;
- Tinago, Willard;
- Alber, Dagmar;
- Hunter, Patricia;
- Luckhurst, Natasha;
- Connolly, Jake;
- Arrigoni, Francesca;
- Abner, Alejandro Garcia;
- Kamngona, Ralph;
- Sheha, Irene;
- Chammudzi, Mishek;
- Jambo, Kondwani;
- Mallewa, Jane;
- Rapala, Alicja;
- Heyderman, Robert S;
- Mallon, Patrick W G;
- Mwandumba, Henry;
- Walker, A Sarah;
- Klein, Nigel;
- Khoo, Saye
Publication type:
Article
Pharmacodynamic Modeling of Bacillary Elimination Rates and Detection of Bacterial Lipid Bodies in Sputum to Predict and Understand Outcomes in Treatment of Pulmonary Tuberculosis.
Published in:
Clinical Infectious Diseases, 2015, v. 61, n. 1, p. 1, doi. 10.1093/cid/civ195
By:
- Sloan, Derek J.;
- Mwandumba, Henry C.;
- Garton, Natalie J.;
- Khoo, Saye H.;
- Butterworth, Anthony E.;
- Allain, Theresa J.;
- Heyderman, Robert S.;
- Corbett, Elizabeth L.;
- Barer, Mike R.;
- Davies, Geraint R.
Publication type:
Article
Asymptomatic HIV-infected individuals on antiretroviral therapy exhibit impaired lung CD4(+) T-cell responses to mycobacteria.
Published in:
2014
By:
- Jambo, Kondwani C;
- Banda, Dominic H;
- Afran, Louise;
- Kankwatira, Anstead M;
- Malamba, Rose D;
- Allain, Theresa J;
- Gordon, Stephen B;
- Heyderman, Robert S;
- Russell, David G;
- Mwandumba, Henry C
Publication type:
journal article
Asymptomatic HIV-infected Individuals on Antiretroviral Therapy Exhibit Impaired Lung CD4<sup>+</sup> T-Cell Responses to Mycobacteria.
Published in:
American Journal of Respiratory & Critical Care Medicine, 2014, v. 190, n. 8, p. 938, doi. 10.1164/rccm.201405-0864OC
By:
- Jambo, Kondwani C.;
- Banda, Dominic H.;
- Afran, Louise;
- Kankwatira, Anstead M.;
- Malamba, Rose D.;
- Allain, Theresa J.;
- Gordon, Stephen B.;
- Heyderman, Robert S.;
- Russell, David G.;
- Mwandumba, Henry C.
Publication type:
Article
TZM-gfp cells: a tractable fluorescent tool for analysis of rare and early HIV-1 infection.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-76422-6
By:
- Gludish, David W.;
- Boliar, Saikat;
- Caldwell, Shannon;
- Tembo, Dumizulu L.;
- Chimbayo, Elizabeth T.;
- Jambo, Kondwani C.;
- Mwandumba, Henry C.;
- Russell, David G.
Publication type:
Article
Functional Analysis of Phagocyte Activity in Whole Blood from HIV/Tuberculosis-Infected Individuals Using a Novel Flow Cytometry-Based Assay.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01222
By:
- Gupta-Wright, Ankur;
- Tembo, Dumizulu;
- Jambo, Kondwani C.;
- Chimbayo, Elizabeth;
- Mvaya, Leonard;
- Caldwell, Shannon;
- Russell, David G.;
- Mwandumba, Henry C.
Publication type:
Article
Perceptions of Research Bronchoscopy in Malawian Adults with Pulmonary Tuberculosis: A Cross-Sectional Study.
Published in:
PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0165734
By:
- McCallum, Andrew D.;
- Nyirenda, Deborah;
- Lora, Wezzie;
- Khoo, Saye H.;
- Sloan, Derek J.;
- Mwandumba, Henry C.;
- Desmond, Nicola;
- Davies, Geraint R.
Publication type:
Article
How Applicable Is the Single-Dose AMBITION Regimen for Human Immunodeficiency Virus–Associated Cryptococcal Meningitis to High-Income Settings?
Published in:
Clinical Infectious Diseases, 2023, v. 76, n. 5, p. 944, doi. 10.1093/cid/ciac792
By:
- Harrison, Thomas S;
- Lawrence, David S;
- Mwandumba, Henry C;
- Boulware, David R;
- Hosseinipour, Mina C;
- Lortholary, Olivier;
- Meintjes, Graeme;
- Mosepele, Mosepele;
- Jarvis, Joseph N
Publication type:
Article
High Intrapulmonary Rifampicin and Isoniazid Concentrations Are Associated With Rapid Sputum Bacillary Clearance in Patients With Pulmonary Tuberculosis.
Published in:
Clinical Infectious Diseases, 2022, v. 75, n. 9, p. 1520, doi. 10.1093/cid/ciac228
By:
- McCallum, Andrew D;
- Pertinez, Henry E;
- Chirambo, Aaron P;
- Sheha, Irene;
- Chasweka, Madalitso;
- Malamba, Rose;
- Shani, Doris;
- Chitani, Alex;
- Mallewa, Jane E;
- Meghji, Jamilah Z;
- Ghany, Jehan F;
- Corbett, Elizabeth L;
- Gordon, Stephen B;
- Davies, Geraint R;
- Khoo, Saye H;
- Sloan, Derek J;
- Mwandumba, Henry C
Publication type:
Article
AstraZeneca COVID-19 vaccine induces robust broadly cross-reactive antibody responses in Malawian adults previously infected with SARS-CoV-2.
Published in:
2022
By:
- Chibwana, Marah G;
- Moyo-Gwete, Thandeka;
- Kwatra, Gaurav;
- Mandolo, Jonathan;
- Hermanaus, Tandile;
- Motlou, Thopisang;
- Mzindle, Nonkululeko;
- Ayres, Frances;
- Chaponda, Mphatso;
- Tembo, Godwin;
- Mwenechanya, Percy;
- Mitole, Ndaona;
- Jassi, Chisomo;
- Kamng'ona, Raphael;
- Afran, Louise;
- Mzinza, David;
- Mwandumba, Henry C;
- Gordon, Stephen B;
- Jere, Khuzwayo;
- Madhi, Shabir
Publication type:
journal article
Serum concentration of anti-Cytomegalovirus IgG and ischaemic stroke in patients with advanced HIV infection in Malawi.
Published in:
PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0208040
By:
- Kamtchum-Tatuene, Joseph;
- Al-Bayati, Zaid;
- Mwandumba, Henry Charles;
- Solomon, Tom;
- Christmas, Stephen E.;
- Benjamin, Laura A.
Publication type:
Article
Defective Monocyte Enzymatic Function and an Inhibitory Immune Phenotype in Human Immunodeficiency Virus-Exposed Uninfected African Infants in the Era of Antiretroviral Therapy.
Published in:
2022
By:
- Afran, Louise;
- Jambo, Kondwani C;
- Nedi, Wilfred;
- Miles, David J C;
- Kiran, Anmol;
- Banda, Dominic H;
- Kamg'ona, Ralph;
- Tembo, Dumizulu;
- Pachnio, Annette;
- Nastouli, Eleni;
- Ferne, Brigit;
- Mwandumba, Henry C;
- Moss, Paul;
- Goldblatt, David;
- Rowland-Jones, Sarah;
- Finn, Adam;
- Heyderman, Robert S
Publication type:
journal article
Incidence of Cardiometabolic Diseases in People With and Without Human Immunodeficiency Virus in the United Kingdom: A Population-Based Matched Cohort Study.
Published in:
2022
By:
- Gooden, Tiffany E;
- Gardner, Mike;
- Wang, Jingya;
- Jolly, Kate;
- Lane, Deirdre A;
- Benjamin, Laura A;
- Mwandumba, Henry C;
- Kandoole, Vanessa;
- Lwanga, Isaac B;
- Taylor, Stephen;
- Manaseki-Holland, Semira;
- Lip, Gregory Y H;
- Nirantharakumar, Krishnarajah;
- Thomas, G Neil
Publication type:
journal article
HIV-Related Arterial Stiffness in Malawian Adults Is Associated With the Proportion of PD-1-Expressing CD8+ T Cells and Reverses With Antiretroviral Therapy.
Published in:
2019
By:
- Kelly, Christine;
- Mwandumba, Henry C;
- Heyderman, Robert S;
- Jambo, Kondwani;
- Kamng'ona, Raphael;
- Chammudzi, Mishek;
- Sheha, Irene;
- Peterson, Ingrid;
- Rapala, Alicja;
- Mallewa, Jane;
- Walker, A Sarah;
- Klein, Nigel;
- Khoo, Saye
Publication type:
journal article
Population pharmacokinetics and CSF penetration of flucytosine in adults with HIV-associated cryptococcal meningoencephalitis.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 4, p. 1015, doi. 10.1093/jac/dkad038
By:
- Stott, Katharine E;
- Ahmadu, Ajisa;
- Kajanga, Cheusisime;
- Moyo, Melanie;
- Gondwe, Ebbie;
- Chimang'anga, Wezzie;
- Chasweka, Madalitso;
- Unsworth, Jennifer;
- Jimenez-Valverde, Ana;
- Jagota, Bhavana;
- Shah, Reya V;
- Lawrence, David S;
- Lalloo, David G;
- Harrison, Tom;
- Jarvis, Joseph N;
- Hope, William;
- Mwandumba, Henry C
Publication type:
Article
Population pharmacokinetics of liposomal amphotericin B in adults with HIV-associated cryptococcal meningoencephalitis.
Published in:
Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 1, p. 276, doi. 10.1093/jac/dkac389
By:
- Stott, Katharine E;
- Moyo, Melanie;
- Ahmadu, Ajisa;
- Kajanga, Cheusisime;
- Gondwe, Ebbie;
- Chimang'anga, Wezzie;
- Chasweka, Madalitso;
- Leeme, Tshepo B;
- Molefi, Mooketsi;
- Chofle, Awilly;
- Bidwell, Gabriella;
- Changalucha, John;
- Unsworth, Jenny;
- Jimenez-Valverde, Ana;
- Lawrence, David S;
- Mwandumba, Henry C;
- Lalloo, David G;
- Harrison, Thomas S;
- Jarvis, Joseph N;
- Hope, William
Publication type:
Article
Heterogeneous loss of HIV transcription and proviral DNA from 8E5/LAV lymphoblastic leukemia cells revealed by RNA FISH:FLOW analyses.
Published in:
Retrovirology, 2016, v. 13, p. 1, doi. 10.1186/s12977-016-0289-2
By:
- Wilburn, Kaley M.;
- Mwandumba, Henry C.;
- Jambo, Kondwani C.;
- Boliar, Saikat;
- Solouki, Sabrina;
- Russell, David G.;
- Gludish, David W.
Publication type:
Article
A comparison of four epidemic waves of COVID-19 in Malawi; an observational cohort study.
Published in:
BMC Infectious Diseases, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12879-022-07941-y
By:
- Anscombe, Catherine;
- Lissauer, Samantha;
- Thole, Herbert;
- Rylance, Jamie;
- Dula, Dingase;
- Menyere, Mavis;
- Kutambe, Belson;
- van der Veer, Charlotte;
- Phiri, Tamara;
- Banda, Ndaziona P.;
- Mndolo, Kwazizira S.;
- Mponda, Kelvin;
- Phiri, Chimota;
- Mallewa, Jane;
- Nyirenda, Mulinda;
- Katha, Grace;
- Mwandumba, Henry;
- Gordon, Stephen B.;
- Jambo, Kondwani C.;
- Cornick, Jennifer
Publication type:
Article

Found: 34