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Mechanisms of Immune Evasion and Bone Tissue Colonization That Make Staphylococcus aureus the Primary Pathogen in Osteomyelitis.
Published in:
Current Osteoporosis Reports, 2019, v. 17, n. 6, p. 395, doi. 10.1007/s11914-019-00548-4
By:
- Muthukrishnan, Gowrishankar;
- Masters, Elysia A.;
- Daiss, John L.;
- Schwarz, Edward M.
Publication type:
Article
Humanized Mouse Models of Bacterial Infections.
Published in:
Antibiotics (2079-6382), 2024, v. 13, n. 7, p. 640, doi. 10.3390/antibiotics13070640
By:
- McDonald, Katya;
- Rodriguez, Adryiana;
- Muthukrishnan, Gowrishankar
Publication type:
Article
Development of Bisphosphonate-Conjugated Antibiotics to Overcome Pharmacodynamic Limitations of Local Therapy: Initial Results with Carbamate Linked Sitafloxacin and Tedizolid.
Published in:
Antibiotics (2079-6382), 2021, v. 10, n. 6, p. 732, doi. 10.3390/antibiotics10060732
By:
- Adjei-Sowah, Emmanuela;
- Peng, Yue;
- Weeks, Jason;
- Jonason, Jennifer H.;
- de Mesy Bentley, Karen L.;
- Masters, Elysia;
- Morita, Yugo;
- Muthukrishnan, Gowrishankar;
- Cherian, Philip;
- Hu, X. Eric;
- McKenna, Charles E.;
- Ebetino, Frank H.;
- Sun, Shuting;
- Schwarz, Edward M.;
- Xie, Chao
Publication type:
Article
Evidence of Neutralizing and Non-Neutralizing Anti-Glucosaminidase Antibodies in Patients With S. Aureus Osteomyelitis and Their Association With Clinical Outcome Following Surgery in a Clinical Pilot.
Published in:
Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.876898
By:
- Sherchand, Shardulendra Prasad;
- Adhikari, Rajan P.;
- Muthukrishnan, Gowrishankar;
- Kanipakala, Tulasikumari;
- Owen, John R.;
- Chao Xie;
- Aman, M. Javad;
- Proctor, Richard A.;
- Schwarz, Edward M.;
- Kates, Stephen L.
Publication type:
Article
Staphylococcus aureus isolates from children with clinically differentiated osteomyelitis exhibit distinct transcriptomic signatures.
Published in:
PLoS ONE, 2023, v. 18, n. 9, p. 1, doi. 10.1371/journal.pone.0288758
By:
- Hachem, Ahmad A.;
- Filkins, Laura M.;
- Kidane, Yared H.;
- Raj, Prithvi;
- Tareen, Naureen G.;
- Arana, Carlos A.;
- Muthukrishnan, Gowrishankar;
- Copley, Lawson A.
Publication type:
Article
Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation.
Published in:
Bone Research, 2022, v. 10, n. 1, p. 1, doi. 10.1038/s41413-022-00228-7
By:
- Morita, Yugo;
- Saito, Motoo;
- Rangel-Moreno, Javier;
- Franchini, Anthony M.;
- Owen, John R.;
- Martinez, John C.;
- Daiss, John L.;
- de Mesy Bentley, Karen L.;
- Kates, Stephen L.;
- Schwarz, Edward M.;
- Muthukrishnan, Gowrishankar
Publication type:
Article
Staphylococcus aureus Cell Wall Biosynthesis Modulates Bone Invasion and Osteomyelitis Pathogenesis.
Published in:
Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.723498
By:
- Masters, Elysia A.;
- Muthukrishnan, Gowrishankar;
- Ho, Lananh;
- Gill, Ann Lindley;
- de Mesy Bentley, Karen L.;
- Galloway, Chad A.;
- McGrath, James L.;
- Awad, Hani A.;
- Gill, Steven R.;
- Schwarz, Edward M.
Publication type:
Article
Evolutionary Analyses of Staphylococcus aureus Identify Genetic Relationships between Nasal Carriage and Clinical Isolates.
Published in:
PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016426
By:
- Lamers, Ryan P.;
- Stinnett, Jason W.;
- Muthukrishnan, Gowrishankar;
- Parkinson, Christopher L.;
- Cole, Alexander M.
Publication type:
Article
Longitudinal genetic analyses of Staphylococcus aureus nasal carriage dynamics in a diverse population.
Published in:
BMC Infectious Diseases, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2334-13-221
By:
- Muthukrishnan, Gowrishankar;
- Lamers, Ryan P.;
- Ellis, Austin;
- Paramanandam, Vanathy;
- Persaud, Alana B.;
- Tafur, Sergio;
- Parkinson, Christopher L.;
- Cole, Alexander M.
Publication type:
Article
Longitudinal genetic analyses of Staphylococcus aureus nasal carriage dynamics in a diverse population.
Published in:
2013
By:
- Muthukrishnan, Gowrishankar;
- Lamers, Ryan P;
- Ellis, Austin;
- Paramanandam, Vanathy;
- Persaud, Alana B;
- Tafur, Sergio;
- Parkinson, Christopher L;
- Cole, Alexander M
Publication type:
journal article
Cutibacterium acnes invades submicron osteocyte lacuno‐canalicular networks following implant‐associated osteomyelitis.
Published in:
Journal of Orthopaedic Research, 2024, v. 42, n. 11, p. 2593, doi. 10.1002/jor.25929
By:
- Botros, Mina;
- de Mesy Bentley, Karen L.;
- Schloemann, Derek T.;
- Saito, Motoo;
- Constantine, Robert;
- Ricciardi, Benjamin F.;
- Muthukrishnan, Gowrishankar
Publication type:
Article
The 2023 Orthopaedic Research Society's International Consensus Meeting on musculoskeletal infection: Summary from the host immunity section.
Published in:
Journal of Orthopaedic Research, 2024, v. 42, n. 3, p. 518, doi. 10.1002/jor.25758
By:
- Schwarz, Edward M.;
- Archer, Nathan K.;
- Atkins, Gerald J.;
- Bentley, Karen L. de Mesy;
- Botros, Mina;
- Cassat, James E.;
- Chisari, Emanuele;
- Coraça‐Huber, Débora C.;
- Daiss, John L.;
- Gill, Steven R.;
- Goodman, Stuart B.;
- Harro, Janette;
- Hernandez, Christopher J.;
- Ivashkiv, Lionel B.;
- Kates, Stephen L.;
- Marques, Cláudia N. H.;
- Masters, Elysia A.;
- Muthukrishnan, Gowrishankar;
- Owen, John R.;
- Raafat, Dina
Publication type:
Article
Longitudinal intravital imaging of the bone marrow for analysis of the race for the surface in a murine osteomyelitis model.
Published in:
Journal of Orthopaedic Research, 2024, v. 42, n. 3, p. 531, doi. 10.1002/jor.25716
By:
- Xie, Chao;
- Ren, Youliang;
- Weeks, Jason;
- Rainbolt, Joshua;
- Kenney, Howard M.;
- Xue, Thomas;
- Allen, Faith;
- Shu, Ye;
- Tay, Allie J. H.;
- Lekkala, Sashank;
- Yeh, Shu‐Chi A.;
- Muthukrishnan, Gowrishankar;
- Gill, Ann L.;
- Gill, Steven R.;
- Kim, Minsoo;
- Kates, Stephen L.;
- Schwarz, Edward M.
Publication type:
Article
Low albumin level is more strongly associated with adverse outcomes and Staphylococcus aureus infection than hemoglobin A1C or smoking tobacco.
Published in:
Journal of Orthopaedic Research, 2022, v. 40, n. 11, p. 2670, doi. 10.1002/jor.25282
By:
- Campbell, Michael P.;
- Mott, Makinzie D.;
- Owen, John R.;
- Reznicek, Julie E.;
- Beck, Christopher A.;
- Muthukrishnan, Gowrishankar;
- Golladay, Gregory J.;
- Kates, Stephen L.
Publication type:
Article
Serum antibodies against Staphylococcus aureus can prognose treatment success in patients with bone infections.
Published in:
Journal of Orthopaedic Research, 2021, v. 39, n. 10, p. 2169, doi. 10.1002/jor.24955
By:
- Muthukrishnan, Gowrishankar;
- Beck, Christopher A.;
- Owen, John R.;
- Xie, Chao;
- Kates, Stephen L.;
- Daiss, John L.
Publication type:
Article
Emerging electron microscopy and 3D methodologies to interrogate Staphylococcus aureus osteomyelitis in murine models.
Published in:
Journal of Orthopaedic Research, 2021, v. 39, n. 2, p. 376, doi. 10.1002/jor.24968
By:
- Mesy Bentley, Karen L.;
- Galloway, Chad A.;
- Muthukrishnan, Gowrishankar;
- Echternacht, Scott R.;
- Masters, Elysia A.;
- Zeiter, Stephan;
- Schwarz, Edward M.;
- Leckenby, Jonathan I.
Publication type:
Article
Distinct expression trend of signature antigens of Staphylococcus aureus osteomyelitis correlated with clinical outcomes.
Published in:
Journal of Orthopaedic Research, 2021, v. 39, n. 2, p. 265, doi. 10.1002/jor.24961
By:
- Fu, Wei;
- He, Wenbin;
- Ren, Youliang;
- Li, Zhengdao;
- Liu, Jinyue;
- Liu, Yi;
- Xie, Zhao;
- Xu, Jianzhong;
- Bi, Qing;
- Kong, Mingxiang;
- Lee, Charles C.;
- Daiss, John L.;
- Muthukrishnan, Gowrishankar;
- Owen, John R.;
- Kates, Stephen L.;
- Peng, Jiachen;
- Xie, Chao
Publication type:
Article
New developments and future challenges in prevention, diagnosis, and treatment of prosthetic joint infection.
Published in:
Journal of Orthopaedic Research, 2020, v. 38, n. 7, p. 1423, doi. 10.1002/jor.24595
By:
- Ricciardi, Benjamin F.;
- Muthukrishnan, Gowrishankar;
- Masters, Elysia A.;
- Kaplan, Nathan;
- Daiss, John L.;
- Schwarz, Edward M.
Publication type:
Article
Interleukin-27 and Its Diverse Effects on Bacterial Infections.
Published in:
Frontiers in Immunology, 2021, v. 12, p. N.PAG, doi. 10.3389/fimmu.2021.678515
By:
- Morita, Yugo;
- Masters, Elysia A.;
- Schwarz, Edward M.;
- Muthukrishnan, Gowrishankar
Publication type:
Article
Humanized Mice Exhibit Exacerbated Abscess Formation and Osteolysis During the Establishment of Implant-Associated Staphylococcus aureus Osteomyelitis.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.651515
By:
- Muthukrishnan, Gowrishankar;
- Wallimann, Alexandra;
- Rangel-Moreno, Javier;
- Bentley, Karen L. de Mesy;
- Hildebrand, Maria;
- Mys, Karen;
- Kenney, H. Mark;
- Sumrall, Eric T.;
- Daiss, John L.;
- Zeiter, Stephan;
- Richards, R. Geoff;
- Schwarz, Edward M.;
- Moriarty, T. Fintan
Publication type:
Article
Increased myocellular lipid and IGFBP‐3 expression in a pre‐clinical model of pancreatic cancer‐related skeletal muscle wasting.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2021, v. 12, n. 3, p. 731, doi. 10.1002/jcsm.12699
By:
- Cole, Calvin L.;
- Bachman, John F.;
- Ye, Jian;
- Murphy, Joseph;
- Gerber, Scott A.;
- Beck, Christopher A.;
- Boyce, Brendan F.;
- Muthukrishnan, Gowrishankar;
- Chakkalakal, Joe V.;
- Schwarz, Edward M.;
- Linehan, David
Publication type:
Article
Phylogenetic relationships among Staphylococcus species and refinement of cluster groups based on multilocus data.
Published in:
BMC Evolutionary Biology, 2012, v. 12, n. 1, p. 171, doi. 10.1186/1471-2148-12-171
By:
- Lamers, Ryan P;
- Muthukrishnan, Gowrishankar;
- Castoe, Todd A;
- Tafur, Sergio;
- Cole, Alexander M;
- Parkinson, Christopher L
Publication type:
Article
Staphylococcus aureus Panton-Valentine Leukocidin worsens acute implant-associated osteomyelitis in humanized BRGSF mice.
Published in:
JBMR Plus, 2024, v. 8, n. 2, p. 1, doi. 10.1093/jbmrpl/ziad005
By:
- Hofstee, Marloes I;
- Siverino, Claudia;
- Saito, Motoo;
- Meghwani, Himanshu;
- Tapia-Dean, James;
- Arveladze, Samson;
- Hildebrand, Maria;
- Rangel-Moreno, Javier;
- Riool, Martijn;
- Zeiter, Stephan;
- Zaat, Sebastian A J;
- Moriarty, T Fintan;
- Muthukrishnan, Gowrishankar
Publication type:
Article

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