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CTLA-4 antibody-drug conjugate reveals autologous destruction of B-lymphocytes associated with regulatory T cell impairment.
- Published in:
- eLife, 2023, p. 1, doi. 10.7554/eLife.87281
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- Article
Soluble CTLA-4 mutants ameliorate immune-related adverse events but preserve efficacy of CTLA-4– and PD-1–targeted immunotherapy.
- Published in:
- Science Translational Medicine, 2023, v. 15, n. 685, p. 1, doi. 10.1126/scitranslmed.abm5663
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- Article
S-15 in combination of Akt inhibitor promotes the expansion of CD45RA<sup>−</sup>CCR7<sup>+</sup> tumor infiltrating lymphocytes with high cytotoxic potential and downregulating PD-1<sup>+</sup>Tim-3<sup>+</sup> cells as well as regulatory T cells.
- Published in:
- Cancer Cell International, 2019, v. 19, n. 1, p. N.PAG, doi. 10.1186/s12935-019-1043-3
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- Article
Donor substrate promiscuity of the N-acetylglucosaminyltransferase activities of Pasteurella multocida heparosan synthase 2 (PmHS2) and Escherichia coli K5 KfiA.
- Published in:
- Applied Microbiology & Biotechnology, 2014, v. 98, n. 3, p. 1127, doi. 10.1007/s00253-013-4947-1
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- Article
Substrate Specificity Provides Insights into the Sugar Donor Recognition Mechanism of <i>O</i>-GlcNAc Transferase (OGT)
- Published in:
- PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063452
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- Article