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Untargeted Liquid Chromatography–High-Resolution Mass Spectrometry Metabolomic Investigation Reveals Altered Lipid Content in Leishmania infantum Lacking Lipid Droplet Protein Kinase.
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- Tropical Medicine & Infectious Disease, 2024, v. 9, n. 9, p. 208, doi. 10.3390/tropicalmed9090208
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- Article
Disruption of multiple copies of the Prostaglandin F2alpha synthase gene affects oxidative stress response and infectivity in Trypanosoma cruzi.
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- PLoS Neglected Tropical Diseases, 2022, v. 16, n. 10, p. 1, doi. 10.1371/journal.pntd.0010845
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Transcriptomic analysis of benznidazole-resistant and susceptible Trypanosoma cruzi populations.
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- Parasites & Vectors, 2023, v. 16, n. 1, p. 1, doi. 10.1186/s13071-023-05775-4
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- Article
Trypanosoma cruzi iron superoxide dismutases: insights from phylogenetics to chemotherapeutic target assessment.
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- Parasites & Vectors, 2022, v. 15, n. 1, p. 1, doi. 10.1186/s13071-022-05319-2
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- Article
Mapping Alterations Induced by Long-Term Axenic Cultivation of Leishmania amazonensis Promastigotes With a Multiplatform Metabolomic Fingerprint Approach.
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- Frontiers in Cellular & Infection Microbiology, 2019, v. 9, p. 1, doi. 10.3389/fcimb.2019.00403
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Unlocking the in vitro anti-Trypanosoma cruzi activity of halophyte plants from the southern Portugal.
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- Asian Pacific Journal of Tropical Medicine, 2016, v. 9, n. 8, p. 735, doi. 10.1016/j.apjtm.2016.06.015
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In Vitro Trypanocidal and Antibacterial Activities of Essential Oils from Four Species of the Family Annonaceae.
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- Chemistry & Biodiversity, 2019, v. 16, n. 11, p. N.PAG, doi. 10.1002/cbdv.201900359
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- Article
Anti- Trypanosoma cruzi Activity, Mutagenicity, Hepatocytotoxicity and Nitroreductase Enzyme Evaluation of 3-Nitrotriazole, 2-Nitroimidazole and Triazole Derivatives.
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- Molecules, 2023, v. 28, n. 22, p. 7461, doi. 10.3390/molecules28227461
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Trypanocidal Activity of Flavanone Derivatives.
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- Molecules, 2020, v. 25, n. 2, p. 397, doi. 10.3390/molecules25020397
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Synthesis of Xylitan Derivatives and Preliminary Evaluation of in Vitro Trypanocidal Activity.
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- Molecules, 2016, v. 21, n. 10, p. 1342, doi. 10.3390/molecules21101342
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- Article
In-Depth Quantitative Proteomics Characterization of In Vitro Selected Miltefosine Resistance in Leishmania infantum.
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- Proteomes, 2022, v. 10, n. 2, p. N.PAG, doi. 10.3390/proteomes10020010
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- Article
Growth arrested live-attenuated Leishmania infantum KHARON1 null mutants display cytokinesis defect and protective immunity in mice.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-30076-7
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- Article
Deletion of the lipid droplet protein kinase gene affects lipid droplets biogenesis, parasite infectivity, and resistance to trivalent antimony in Leishmania infantum.
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- PLoS Neglected Tropical Diseases, 2024, v. 18, n. 1, p. 1, doi. 10.1371/journal.pntd.0011880
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Impact of Genetic Diversity and Genome Plasticity of Leishmania spp. in Treatment and the Search for Novel Chemotherapeutic Targets.
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- Frontiers in Cellular & Infection Microbiology, 2022, p. 1, doi. 10.3389/fcimb.2022.826287
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- Article
Downregulation of FeSOD-A expression in Leishmania infantum alters trivalent antimony and miltefosine susceptibility.
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- Parasites & Vectors, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13071-021-04838-8
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Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines.
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- Parasites & Vectors, 2020, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13071-020-04486-4
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- Article
New 2‐nitroimidazole‐N‐acylhydrazones, analogs of benznidazole, as anti‐Trypanosoma cruzi agents.
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- Archiv der Pharmazie, 2024, v. 357, n. 7, p. 1, doi. 10.1002/ardp.202400059
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Perspectives From Systems Biology to Improve Knowledge of Leishmania Drug Resistance.
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- Frontiers in Cellular & Infection Microbiology, 2021, v. 11, p. N.PAG, doi. 10.3389/fcimb.2021.653670
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Aldo-keto reductase and alcohol dehydrogenase contribute to benznidazole natural resistance in Trypanosoma cruzi.
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- Molecular Microbiology, 2017, v. 106, n. 5, p. 704, doi. 10.1111/mmi.13830
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Evaluation and discovery of novel benzothiazole derivatives as promising hits against Leishmania infantum.
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- Chemical Biology & Drug Design, 2024, v. 103, n. 4, p. 1, doi. 10.1111/cbdd.14525
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Design, synthesis, molecular modelling, and in vitro evaluation of tricyclic coumarins against Trypanosoma cruzi.
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- Chemical Biology & Drug Design, 2019, v. 93, n. 3, p. 337, doi. 10.1111/cbdd.13420
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Fungi in glacial ice of Antarctica: diversity, distribution and bioprospecting of bioactive compounds.
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- Extremophiles, 2020, v. 24, n. 3, p. 367, doi. 10.1007/s00792-020-01161-5
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Synthesis, Design, and Structure‐Activity Relationship of a Benzenesulfonylpiperazine Series against Trypanosoma cruzi.
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- ChemMedChem, 2022, v. 17, n. 19, p. 1, doi. 10.1002/cmdc.202200211
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Mannosyltransferase (GPI-14) overexpression protects promastigote and amastigote forms of Leishmania braziliensis against trivalent antimony.
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- Parasites & Vectors, 2019, v. 12, n. 1, p. 1, doi. 10.1186/s13071-019-3305-2
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- Article