Works matching AU Munoz-Sanjuan, Ignacio


Results: 41
    1

    Quantifying autophagy using novel LC3B and p62 TR-FRET assays.

    Published in:
    PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0194423
    By:
    • Bresciani, Alberto;
    • Spiezia, Maria Carolina;
    • Boggio, Roberto;
    • Cariulo, Cristina;
    • Nordheim, Anja;
    • Altobelli, Roberta;
    • Kuhlbrodt, Kirsten;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Wityak, John;
    • Fodale, Valentina;
    • Marchionini, Deanna M.;
    • Weiss, Andreas
    Publication type:
    Article
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    Establishment of an in Vitro Human Blood-Brain Barrier Model Derived from Induced Pluripotent Stem Cells and Comparison to a Porcine Cell-Based System.

    Published in:
    Cells (2073-4409), 2020, v. 9, n. 4, p. 994, doi. 10.3390/cells9040994
    By:
    • Di Marco, Annalise;
    • Vignone, Domenico;
    • Gonzalez Paz, Odalys;
    • Fini, Ivan;
    • Battista, Maria Rosaria;
    • Cellucci, Antonella;
    • Bracacel, Elena;
    • Auciello, Giulio;
    • Veneziano, Maria;
    • Khetarpal, Vinod;
    • Rose, Mark;
    • Rosa, Alessandro;
    • Gloaguen, Isabelle;
    • Monteagudo, Edith;
    • Herbst, Todd;
    • Dominguez, Celia;
    • Muñoz-Sanjuán, Ignacio
    Publication type:
    Article
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    Quantification Assays for Total and Polyglutamine-Expanded Huntingtin Proteins.

    Published in:
    PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096854
    By:
    • Macdonald, Douglas;
    • Tessari, Michela A.;
    • Boogaard, Ivette;
    • Smith, Melanie;
    • Pulli, Kristiina;
    • Szynol, Agnieszka;
    • Albertus, Faywell;
    • Lamers, Marieke B. A. C.;
    • Dijkstra, Sipke;
    • Kordt, Daniel;
    • Reindl, Wolfgang;
    • Herrmann, Frank;
    • McAllister, George;
    • Fischer, David F.;
    • Munoz-Sanjuan, Ignacio
    Publication type:
    Article
    9

    A Monoclonal Antibody TrkB Receptor Agonist as a Potential Therapeutic for Huntington’s Disease.

    Published in:
    PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0087923
    By:
    • Todd, Daniel;
    • Gowers, Ian;
    • Dowler, Simon J.;
    • Wall, Michael D.;
    • McAllister, George;
    • Fischer, David F.;
    • Dijkstra, Sipke;
    • Fratantoni, Silvina A.;
    • van de Bospoort, Rhea;
    • Veenman-Koepke, Jessica;
    • Flynn, Geraldine;
    • Arjomand, Jamshid;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Wityak, John;
    • Bard, Jonathan A.
    Publication type:
    Article
    10

    Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease.

    Published in:
    PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0050717
    By:
    • Heikkinen, Taneli;
    • Lehtimäki, Kimmo;
    • Vartiainen, Nina;
    • Puoliväli, Jukka;
    • Hendricks, Susan J.;
    • Glaser, Jack R.;
    • Bradaia, Amyaouch;
    • Wadel, Kristian;
    • Touller, Chrystelle;
    • Kontkanen, Outi;
    • Yrjänheikki, Juha M.;
    • Buisson, Bruno;
    • Howland, David;
    • Beaumont, Vahri;
    • Munoz-Sanjuan, Ignacio;
    • Park, Larry C.
    Publication type:
    Article
    11

    Oral Administration of the Pimelic Diphenylamide HDAC Inhibitor HDACi 4b Is Unsuitable for Chronic Inhibition of HDAC Activity in the CNS In Vivo.

    Published in:
    PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0044498
    By:
    • Beconi, Maria;
    • Aziz, Omar;
    • Matthews, Kim;
    • Moumné, Lara;
    • O'Connell, Catherine;
    • Yates, Dawn;
    • Clifton, Steven;
    • Pett, Hannah;
    • Vann, Julie;
    • Crowley, Lynsey;
    • Haughan, Alan F.;
    • Smith, Donna L.;
    • Woodman, Ben;
    • Bates, Gillian P.;
    • Brookfield, Fred;
    • Bürli, Roland W.;
    • McAllister, George;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Beaumont, Vahri
    Publication type:
    Article
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    Preclinical evaluation of the novel [<sup>18</sup>F]CHDI-650 PET ligand for non-invasive quantification of mutant huntingtin aggregates in Huntington's disease.

    Published in:
    European Journal of Nuclear Medicine & Molecular Imaging, 2024, v. 52, n. 1, p. 122, doi. 10.1007/s00259-024-06880-x
    By:
    • Zajicek, Franziska;
    • Verhaeghe, Jeroen;
    • De Lombaerde, Stef;
    • Van Eetveldt, Annemie;
    • Miranda, Alan;
    • Munoz-Sanjuan, Ignacio;
    • Dominguez, Celia;
    • Khetarpal, Vinod;
    • Bard, Jonathan;
    • Liu, Longbin;
    • Staelens, Steven;
    • Bertoglio, Daniele
    Publication type:
    Article
    16

    Biodistribution and dosimetry in human healthy volunteers of the PET radioligands [<sup>11</sup>C]CHDI-00485180-R and [<sup>11</sup>C]CHDI-00485626, designed for quantification of cerebral aggregated mutant huntingtin.

    Published in:
    European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 50, n. 1, p. 48, doi. 10.1007/s00259-022-05945-z
    By:
    • Delva, Aline;
    • Koole, Michel;
    • Serdons, Kim;
    • Bormans, Guy;
    • Liu, Longbin;
    • Bard, Jonathan;
    • Khetarpal, Vinod;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Wood, Andrew;
    • Skinbjerg, Mette;
    • Wang, Yuchuan;
    • Vandenberghe, Wim;
    • Van Laere, Koen
    Publication type:
    Article
    17

    The PDE1/5 Inhibitor SCH51866 Does Not Modify Disease Progression in the R6/2 Mouse Model of Huntington's Disease.

    Published in:
    PLoS Currents, 2014, p. 572, doi. 10.1371/currents.hd.3304e87e460b4bb0dc519a29f4deccca
    By:
    • Beaumont, Vahri;
    • Park, Larry;
    • Rassoulpour, Arash;
    • Dijkman, Ulrike;
    • Heikkinen, Taneli;
    • Lehtimaki, Kimmo;
    • Kontkanen, Outi;
    • Nackkash, Rand Al;
    • Bates, Gillian P.;
    • Gleyzes, Melanie;
    • Steidl, Esther;
    • Ramboz, Sylvie;
    • Murphy, Carol;
    • Beconi, Maria G.;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio
    Publication type:
    Article
    18

    Pharmacokinetics of memantine in rats and mice.

    Published in:
    PLoS Currents, 2011, p. 495, doi. 10.1371/currents.RRN1291
    By:
    • Beconi, Maria G.;
    • Howland, David;
    • Park, Larry;
    • Lyons, Kathryn;
    • Giuliano, Joseph;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Pacifici, Robert
    Publication type:
    Article
    19

    In Vivo Cerebral Imaging of Mutant Huntingtin Aggregates Using <sup>11</sup>C-CHDI-180R PET in a Nonhuman Primate Model of Huntington Disease.

    Published in:
    Journal of Nuclear Medicine, 2023, v. 64, n. 10, p. 1581, doi. 10.2967/jnumed.123.265569
    By:
    • Bertoglio, Daniele;
    • Weiss, Alison R.;
    • Liguore, William;
    • Martin, Lauren Drew;
    • Hobbs, Theodore;
    • Templon, John;
    • Srinivasan, Sathya;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Khetarpal, Vinod;
    • Verhaeghe, Jeroen;
    • Staelens, Steven;
    • Link, Jeanne;
    • Liu, Longbin;
    • Bard, Jonathan A.;
    • McBride, Jodi L.
    Publication type:
    Article
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    Longitudinal Small-Animal PET Imaging of the zQ175 Mouse Model of Huntington Disease Shows In Vivo Changes of Molecular Targets in the Striatum and Cerebral Cortex.

    Published in:
    Journal of Nuclear Medicine, 2017, v. 58, n. 4, p. 617, doi. 10.2967/jnumed.116.180497
    By:
    • Häggkvist, Jenny;
    • Tóth, Miklós;
    • Tari, Lenke;
    • Varnäs, Katarina;
    • Svedberg, Marie;
    • Forsberg, Anton;
    • Nag, Sangram;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Bard, Jonathan;
    • Wityak, John;
    • Varrone, Andrea;
    • Halldin, Christer;
    • Mrzljak, Ladislav
    Publication type:
    Article
    24

    Validation and noninvasive kinetic modeling of [ 11 C]UCB-J PET imaging in mice.

    Published in:
    Journal of Cerebral Blood Flow & Metabolism, 2020, v. 40, n. 6, p. 1351, doi. 10.1177/0271678X19864081
    By:
    • Bertoglio, Daniele;
    • Verhaeghe, Jeroen;
    • Miranda, Alan;
    • Kertesz, Istvan;
    • Cybulska, Klaudia;
    • Korat, Špela;
    • Wyffels, Leonie;
    • Stroobants, Sigrid;
    • Mrzljak, Ladislav;
    • Dominguez, Celia;
    • Liu, Longbin;
    • Skinbjerg, Mette;
    • Munoz-Sanjuan, Ignacio;
    • Staelens, Steven
    Publication type:
    Article
    25

    Longitudinal preclinical evaluation of the novel radioligand [11C]CHDI-626 for PET imaging of mutant huntingtin aggregates in Huntington's disease.

    Published in:
    European Journal of Nuclear Medicine & Molecular Imaging, 2022, v. 49, n. 4, p. 1166, doi. 10.1007/s00259-021-05578-8
    By:
    • Bertoglio, Daniele;
    • Verhaeghe, Jeroen;
    • Miranda, Alan;
    • Wyffels, Leonie;
    • Stroobants, Sigrid;
    • Mrzljak, Ladislav;
    • Khetarpal, Vinod;
    • Skinbjerg, Mette;
    • Liu, Longbin;
    • Dominguez, Celia;
    • Munoz-Sanjuan, Ignacio;
    • Bard, Jonathan;
    • Staelens, Steven
    Publication type:
    Article
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    Longitudinal alterations in brain perfusion and vascular reactivity in the zQ175DN mouse model of Huntington's disease.

    Published in:
    Journal of Biomedical Science, 2024, v. 31, n. 1, p. 1, doi. 10.1186/s12929-024-01028-3
    By:
    • Vasilkovska, Tamara;
    • Salajeghe, Somaie;
    • Vanreusel, Verdi;
    • Van Audekerke, Johan;
    • Verschuuren, Marlies;
    • Hirschler, Lydiane;
    • Warnking, Jan;
    • Pintelon, Isabel;
    • Pustina, Dorian;
    • Cachope, Roger;
    • Mrzljak, Ladislav;
    • Muñoz-Sanjuan, Ignacio;
    • Barbier, Emmanuel L.;
    • De Vos, Winnok H.;
    • Van der Linden, Annemie;
    • Verhoye, Marleen
    Publication type:
    Article
    28

    Longitudinal alterations in brain perfusion and vascular reactivity in the zQ175DN mouse model of Huntington's disease.

    Published in:
    Journal of Biomedical Science, 2024, v. 31, p. 1, doi. 10.1186/s12929-024-01028-3
    By:
    • Vasilkovska, Tamara;
    • Salajeghe, Somaie;
    • Vanreusel, Verdi;
    • Van Audekerke, Johan;
    • Verschuuren, Marlies;
    • Hirschler, Lydiane;
    • Warnking, Jan;
    • Pintelon, Isabel;
    • Pustina, Dorian;
    • Cachope, Roger;
    • Mrzljak, Ladislav;
    • Muñoz-Sanjuan, Ignacio;
    • Barbier, Emmanuel L.;
    • De Vos, Winnok H.;
    • Van der Linden, Annemie;
    • Verhoye, Marleen
    Publication type:
    Article
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    Human glia can both induce and rescue aspects of disease phenotype in Huntington disease.

    Published in:
    Nature Communications, 2016, v. 7, n. 6, p. 11758, doi. 10.1038/ncomms11758
    By:
    • Benraiss, Abdellatif;
    • Wang, Su;
    • Herrlinger, Stephanie;
    • Li, Xiaojie;
    • Chandler-Militello, Devin;
    • Mauceri, Joseph;
    • Burm, Hayley B.;
    • Toner, Michael;
    • Osipovitch, Mikhail;
    • Jim Xu, Qiwu;
    • Ding, Fengfei;
    • Wang, Fushun;
    • Kang, Ning;
    • Kang, Jian;
    • Curtin, Paul C.;
    • Brunner, Daniela;
    • Windrem, Martha S.;
    • Munoz-Sanjuan, Ignacio;
    • Nedergaard, Maiken;
    • Goldman, Steven A.
    Publication type:
    Article
    38

    Modelling the Human Blood–Brain Barrier in Huntington Disease.

    Published in:
    International Journal of Molecular Sciences, 2022, v. 23, n. 14, p. 7813, doi. 10.3390/ijms23147813
    By:
    • Vignone, Domenico;
    • Gonzalez Paz, Odalys;
    • Fini, Ivan;
    • Cellucci, Antonella;
    • Auciello, Giulio;
    • Battista, Maria Rosaria;
    • Gloaguen, Isabelle;
    • Fortuni, Silvia;
    • Cariulo, Cristina;
    • Khetarpal, Vinod;
    • Dominguez, Celia;
    • Muñoz-Sanjuán, Ignacio;
    • Di Marco, Annalise
    Publication type:
    Article
    39

    Development of mAb-based polyglutamine-dependent and polyglutamine length-independent huntingtin quantification assays with cross-site validation.

    Published in:
    PLoS ONE, 2022, v. 17, n. 4, p. 1, doi. 10.1371/journal.pone.0266812
    By:
    • Fischer, David F.;
    • Dijkstra, Sipke;
    • Lo, Kimberly;
    • Suijker, Johnny;
    • Correia, Ana C. P.;
    • Naud, Patricia;
    • Poirier, Martin;
    • Tessari, Michela A.;
    • Boogaard, Ivette;
    • Flynn, Geraldine;
    • Visser, Mijke;
    • Lamers, Marieke B. A. C.;
    • McAllister, George;
    • Munoz-Sanjuan, Ignacio;
    • Macdonald, Douglas
    Publication type:
    Article
    40

    Global Rhes knockout in the Q175 Huntington's disease mouse model.

    Published in:
    PLoS ONE, 2021, v. 16, n. 10, p. 1, doi. 10.1371/journal.pone.0258486
    By:
    • Heikkinen, Taneli;
    • Bragge, Timo;
    • Kuosmanen, Juha;
    • Parkkari, Teija;
    • Gustafsson, Sanna;
    • Kwan, Mei;
    • Beltran, Jose;
    • Ghavami, Afshin;
    • Subramaniam, Srinivasa;
    • Shahani, Neelam;
    • Ramírez-Jarquín, Uri Nimrod;
    • Park, Larry;
    • Muñoz-Sanjuán, Ignacio;
    • Marchionini, Deanna M.
    Publication type:
    Article
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