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Antisense Therapy Attenuates Phospholamban p.(Arg14del) Cardiomyopathy in Mice and Reverses Protein Aggregation.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 5, p. 2427, doi. 10.3390/ijms23052427
By:
- Eijgenraam, Tim R.;
- Stege, Nienke M.;
- Oliveira Nunes Teixeira, Vivian;
- de Brouwer, Remco;
- Schouten, Elisabeth M.;
- Grote Beverborg, Niels;
- Sun, Liu;
- Später, Daniela;
- Knöll, Ralph;
- Hansson, Kenny M.;
- Amilon, Carl;
- Janzén, David;
- Yeh, Steve T.;
- Mullick, Adam E.;
- van der Meer, Peter;
- de Boer, Rudolf A.;
- Silljé, Herman H. W.
Publication type:
Article
Modulation of atherosclerosis in mice by Toll-like receptor 2.
Published in:
2005
By:
- Mullick, Adam E.;
- Tobias, Peter S.;
- Curtiss, Linda K.
Publication type:
journal article
Antisense oligonucleotides targeting angiotensinogen: insights from animal studies.
Published in:
Bioscience Reports, 2019, v. 39, n. 1, p. 1, doi. 10.1042/BSR20180201
By:
- Chia-Hua Wu;
- Ya Wang;
- Murong Ma;
- Mullick, Adam E.;
- Crooke, Rosanne M.;
- Graham, Mark J.;
- Daugherty, Alan;
- Hong S. Lu
Publication type:
Article
Chemerin as a Driver of Hypertension: A Consideration.
Published in:
American Journal of Hypertension, 2020, v. 33, n. 11, p. 975, doi. 10.1093/ajh/hpaa084
By:
- Ferland, David J;
- Mullick, Adam E;
- Watts, Stephanie W
Publication type:
Article
Reducing YAP expression in Pkd1 mutant mice does not improve the cystic phenotype.
Published in:
Journal of Cellular & Molecular Medicine, 2020, v. 24, n. 15, p. 8876, doi. 10.1111/jcmm.15512
By:
- Formica, Chiara;
- Kunnen, Sandra;
- Dauwerse, Johannes G.;
- Mullick, Adam E.;
- Dijkstra, Kyra L.;
- Scharpfenecker, Marion;
- Peters, Dorien J. M.
Publication type:
Article
The chemerin knockout rat reveals chemerin dependence in female, but not male, experimental hypertension.
Published in:
FASEB Journal, 2018, v. 32, n. 12, p. 6596, doi. 10.1096/fj.201800479
By:
- Watts, Stephanie W.;
- Darios, Emma S.;
- Mullick, Adam E.;
- Garver, Hannah;
- Saunders, Thomas L.;
- Hughes, Elizabeth D.;
- Filipiak, Wanda E.;
- Zeidler, Michael G.;
- McMullen, Nichole;
- Sinal, Christopher J.;
- Kumar, Ramya K.;
- Ferland, David J.;
- Fink, Gregory D.
Publication type:
Article
Suppressing angiotensinogen synthesis attenuates kidney cyst formation in a Pkd1 mouse model.
Published in:
FASEB Journal, 2016, v. 30, n. 1, p. 370, doi. 10.1096/fj.15-279299
By:
- Takamitsu Saigusa;
- Yujing Dang;
- Mullick, Adam E.;
- Yeh, Steve T.;
- Zile, Michael R.;
- Baicu, Catalin F.;
- Bell, P. Darwin
Publication type:
Article
Eruptive xanthoma model reveals endothelial cells internalize and metabolize chylomicrons, leading to extravascular triglyceride accumulation.
Published in:
2021
By:
- Cabodevilla, Ainara G.;
- Songtao Tang;
- Sungwoon Lee;
- Mullick, Adam E.;
- Aleman, Jose O.;
- Hussain, M. Mahmood;
- Sessa, William C.;
- Abumrad, Nada A.;
- Goldberg, Ira J.;
- Tang, Songtao;
- Lee, Sungwoon
Publication type:
journal article
Endothelial cell CD36 optimizes tissue fatty acid uptake.
Published in:
2018
By:
- Ni-Huiping Son;
- Basu, Debapriya;
- Samovski, Dmitri;
- Pietka, Terri A.;
- Peche, Vivek S.;
- Willecke, Florian;
- Xiang Fang;
- Shui-Qing Yu;
- Scerbo, Diego;
- Hye Rim Chang;
- Fei Sun;
- Bagdasarov, Svetlana;
- Drosatos, Konstantinos;
- Yeh, Steve T.;
- Mullick, Adam E.;
- Shoghi, Kooresh I.;
- Gumaste, Namrata;
- Kyeong Jin Kim;
- Huggins, Lesley-Ann;
- Lhakhang, Tenzin
Publication type:
journal article
ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors.
Published in:
2016
By:
- Gordts, Philip L. S. M.;
- Nock, Ryan;
- Ni-Huiping Son;
- Ramms, Bastian;
- Lew, Irene;
- Gonzales, Jon C.;
- Thacker, Bryan E.;
- Basu, Debapriya;
- Lee, Richard G.;
- Mullick, Adam E.;
- Graham, Mark J.;
- Goldberg, Ira J.;
- Crooke, Rosanne M.;
- Witztum, Joseph L.;
- Esko, Jeffrey D.;
- Son, Ni-Huiping
Publication type:
journal article
CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation.
Published in:
Nature Immunology, 2013, v. 14, n. 8, p. 812, doi. 10.1038/ni.2639
By:
- Sheedy, Frederick J;
- Grebe, Alena;
- Rayner, Katey J;
- Kalantari, Parisa;
- Ramkhelawon, Bhama;
- Carpenter, Susan B;
- Becker, Christine E;
- Ediriweera, Hasini N;
- Mullick, Adam E;
- Golenbock, Douglas T;
- Stuart, Lynda M;
- Latz, Eicke;
- Fitzgerald, Katherine A;
- Moore, Kathryn J
Publication type:
Article
An mTOR anti-sense oligonucleotide decreases polycystic kidney disease in mice with a targeted mutation in Pkd2.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 18, p. 4919, doi. 10.1093/hmg/ddu208
By:
- Ravichandran, Kameswaran;
- Zafar, Iram;
- He, Zhibin;
- Doctor, R. Brian;
- Moldovan, Radu;
- Mullick, Adam E.;
- Edelstein, Charles L.
Publication type:
Article
Divergence of Chemerin Reduction by an ATS9R Nanoparticle Targeting Adipose Tissue In Vitro vs. In Vivo in the Rat.
Published in:
Biomedicines, 2022, v. 10, n. 7, p. N.PAG, doi. 10.3390/biomedicines10071635
By:
- Orr, Alexis;
- Liu, Kunli;
- Mullick, Adam E.;
- Huang, Xuefei;
- Watts, Stephanie W.
Publication type:
Article
Conjugation of hydrophobic moieties enhances potency of antisense oligonucleotides in the muscle of rodents and non-human primates.
Published in:
Nucleic Acids Research, 2019, v. 47, n. 12, p. 6045, doi. 10.1093/nar/gkz360
By:
- Østergaard, Michael E;
- Jackson, Michaela;
- Low, Audrey;
- E. Chappell, Alfred;
- G. Lee, Richard;
- Peralta, Rachel Q;
- Yu, Jinghua;
- Kinberger, Garth A;
- Dan, Amy;
- Carty, Rick;
- Tanowitz, Michael;
- Anderson, Patrick;
- Kim, Tae-Won;
- Fradkin, Linda;
- Mullick, Adam E;
- Murray, Sue;
- Rigo, Frank;
- Prakash, Thazha P;
- Bennett, C Frank;
- Swayze, Eric E
Publication type:
Article
Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle.
Published in:
Nucleic Acids Research, 2019, v. 47, n. 12, p. 6029, doi. 10.1093/nar/gkz354
By:
- Prakash, Thazha P;
- Mullick, Adam E;
- Lee, Richard G;
- Yu, Jinghua;
- Yeh, Steve T;
- Low, Audrey;
- Chappell, Alfred E;
- Østergaard, Michael E;
- Murray, Sue;
- Gaus, Hans J;
- Swayze, Eric E;
- Seth, Punit P
Publication type:
Article
Therapeutic inhibition of RBM20 improves diastolic function in a murine heart failure model and human engineered heart tissue.
Published in:
Science Translational Medicine, 2021, v. 13, n. 622, p. 1, doi. 10.1126/scitranslmed.abe8952
By:
- Radke, Michael H.;
- Badillo-Lisakowski, Victor;
- Britto-Borges, Thiago;
- Kubli, Dieter A.;
- Jüttner, René;
- Parakkat, Pragati;
- Carballo, Jacobo Lopez;
- Hüttemeister, Judith;
- Liss, Martin;
- Hansen, Arne;
- Dieterich, Christoph;
- Mullick, Adam E.;
- Gotthardt, Michael
Publication type:
Article
2066-P: Dyrk1a Antisense Oligonucleotides Conjugated to GLP-1R Agonist Promote Pancreatic Beta-Cell Proliferation.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2066-P
By:
- FU, WUXIA;
- LEE, RICHARD;
- PIRIE, ELAINE C.;
- PRAKASH, THAZHA;
- MURRAY, SUE;
- POWERS, ANDREW;
- MULLICK, ADAM E.;
- CROOKE, ROSANNE M.
Publication type:
Article

Found: 17