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Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.
Published in:
Nature Medicine, 2012, v. 18, n. 12, p. 1857, doi. 10.1038/nm1212-1857a
By:
- Kwong, Lawrence N;
- Costello, James C;
- Liu, Huiyun;
- Jiang, Shan;
- Helms, Timothy L;
- Langsdorf, Aliete E;
- Jakubosky, David;
- Genovese, Giannicola;
- Muller, Florian L;
- Jeong, Joseph H;
- Bender, Ryan P;
- Chu, Gerald C;
- Flaherty, Keith T;
- Wargo, Jennifer A;
- Collins, James J;
- Chin, Lynda
Publication type:
Article
Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.
Published in:
Nature Medicine, 2012, v. 18, n. 10, p. 1503, doi. 10.1038/nm.2941
By:
- Kwong, Lawrence N;
- Costello, James C;
- Liu, Huiyun;
- Jiang, Shan;
- Helms, Timothy L;
- Langsdorf, Aliete E;
- Jakubosky, David;
- Genovese, Giannicola;
- Muller, Florian L;
- Jeong, Joseph H;
- Bender, Ryan P;
- Chu, Gerald C;
- Flaherty, Keith T;
- Wargo, Jennifer A;
- Collins, James J;
- Chin, Lynda
Publication type:
Article
Targeting Host Glycolysis as a Strategy for Antimalarial Development.
Published in:
Frontiers in Cellular & Infection Microbiology, 2021, v. 11, p. 1, doi. 10.3389/fcimb.2021.730413
By:
- Jezewski, Andrew J.;
- Lin, Yu-Hsi;
- Reisz, Julie A.;
- Culp-Hill, Rachel;
- Barekatain, Yasaman;
- Yan, Victoria C.;
- D'Alessandro, Angelo;
- Muller, Florian L.;
- Odom John, Audrey R.
Publication type:
Article
MnSOD deficiency has a differential effect on disease progression in two different ALS mutant mouse models.
Published in:
Muscle & Nerve, 2008, v. 38, n. 3, p. 1173, doi. 10.1002/mus.21049
By:
- Muller, Florian L.;
- Liu, Yuhong;
- Jernigan, Amanda;
- Borchelt, David;
- Richardson, Arlan;
- Van Remmen, Holly
Publication type:
Article
Structure-guided microbial targeting of antistaphylococcal prodrugs.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.66657
By:
- Miller, Justin J.;
- Shah, Ishaan T.;
- Hatten, Jayda;
- Barekatain, Yasaman;
- Mueller, Elizabeth A.;
- Moustafa, Ahmed M.;
- Edwards, Rachel L.;
- Dowd, Cynthia S.;
- Planet, Paul J.;
- Muller, Florian L.;
- Jez, Joseph M.;
- Odom John, Audrey R.
Publication type:
Article
Telomere dysfunction induces metabolic and mitochondrial compromise.
Published in:
2011
By:
- Sahin, Ergün;
- Colla, Simona;
- Liesa, Marc;
- Moslehi, Javid;
- Müller, Florian L.;
- Guo, Mira;
- Cooper, Marcus;
- Kotton, Darrell;
- Fabian, Attila J.;
- Walkey, Carl;
- Maser, Richard S.;
- Tonon, Giovanni;
- Foerster, Friedrich;
- Xiong, Robert;
- Wang, Y. Alan;
- Shukla, Sachet A.;
- Jaskelioff, Mariela;
- Martin, Eric S.;
- Heffernan, Timothy P.;
- Protopopov, Alexei
Publication type:
Correction Notice
Telomere dysfunction induces metabolic and mitochondrial compromise.
Published in:
Nature, 2011, v. 470, n. 7334, p. 359, doi. 10.1038/nature09787
By:
- Sahin, Ergün;
- Colla, Simona;
- Liesa, Marc;
- Moslehi, Javid;
- Müller, Florian L.;
- Guo, Mira;
- Cooper, Marcus;
- Kotton, Darrell;
- Fabian, Attila J.;
- Walkey, Carl;
- Maser, Richard S.;
- Tonon, Giovanni;
- Foerster, Friedrich;
- Robert Xiong;
- Y. Alan Wang;
- Shukla, Sachet A.;
- Jaskelioff, Mariela;
- Martin, Eric S.;
- Heffernan, Timothy P.;
- Protopopov, Alexei
Publication type:
Article
Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.
Published in:
Nature, 2011, v. 469, n. 7328, p. 102, doi. 10.1038/nature09603
By:
- Jaskelioff, Mariela;
- Muller, Florian L.;
- Paik, Ji-Hye;
- Thomas, Emily;
- Jiang, Shan;
- Adams, Andrew C.;
- Sahin, Ergun;
- Kost-Alimova, Maria;
- Protopopov, Alexei;
- Cadiñanos, Juan;
- Horner, James W.;
- Maratos-Flier, Eleftheria;
- DePinho, Ronald A.
Publication type:
Article
Robust detection of oncometabolic aberrations by 1H–13C heteronuclear single quantum correlation in intact biological specimens.
Published in:
Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-1055-5
By:
- Barekatain, Yasaman;
- Yan, Victoria C.;
- Arthur, Kenisha;
- Ackroyd, Jeffrey J.;
- Khadka, Sunada;
- De Groot, John;
- Huse, Jason T.;
- Muller, Florian L.
Publication type:
Article
Superoxide-mediated oxidative stress accelerates skeletal muscle atrophy by synchronous activation of proteolytic systems.
Published in:
GeroScience, 2020, v. 42, n. 6, p. 1579, doi. 10.1007/s11357-020-00200-5
By:
- Jang, Young C.;
- Rodriguez, Karl;
- Lustgarten, Michael S.;
- Muller, Florian L.;
- Bhattacharya, Arunabh;
- Pierce, Anson;
- Choi, Jeongmoon J.;
- Lee, Nan Hee;
- Chaudhuri, Asish;
- Richardson, Arlan G.;
- Van Remmen, Holly
Publication type:
Article
Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration.
Published in:
FASEB Journal, 2010, v. 24, n. 5, p. 1376, doi. 10.1096/fj.09-146308
By:
- Jang, Youngmok C.;
- Lustgarten, Michael S.;
- Yuhong Liu;
- Muller, Florian L.;
- Bhattacharya, Arunabh;
- Hanyu Liang;
- Salmon, Adam B.;
- Brooks, Susan V.;
- Larkin, Lisa;
- Hayworth, Christopher R.;
- Richardson, Arlan;
- Van Remmen, Holly
Publication type:
Article
Correction: Cook et al. An Optimized Bioassay for Screening Combined Anticoronaviral Compounds for Efficacy against Feline Infectious Peritonitis Virus with Pharmacokinetic Analyses of GS-441524, Remdesivir, and Molnupiravir in Cats. Viruses 2022, 14 , 2429
Published in:
2024
By:
- Cook, Sarah;
- Wittenburg, Luke;
- Yan, Victoria C.;
- Theil, Jacob H.;
- Castillo, Diego;
- Reagan, Krystle L.;
- Williams, Sonyia;
- Pham, Cong-Dat;
- Li, Chun;
- Muller, Florian L.;
- Murphy, Brian G.
Publication type:
Correction Notice
An Optimized Bioassay for Screening Combined Anticoronaviral Compounds for Efficacy against Feline Infectious Peritonitis Virus with Pharmacokinetic Analyses of GS-441524, Remdesivir, and Molnupiravir in Cats.
Published in:
Viruses (1999-4915), 2022, v. 14, n. 11, p. 2429, doi. 10.3390/v14112429
By:
- Cook, Sarah;
- Wittenburg, Luke;
- Yan, Victoria C.;
- Theil, Jacob H.;
- Castillo, Diego;
- Reagan, Krystle L.;
- Williams, Sonyia;
- Pham, Cong-Dat;
- Li, Chun;
- Muller, Florian L.;
- Murphy, Brian G.
Publication type:
Article
ENOblock Does Not Inhibit the Activity of the Glycolytic Enzyme Enolase.
Published in:
PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0168739
By:
- Satani, Nikunj;
- Lin, Yu-Hsi;
- Hammoudi, Naima;
- Raghavan, Sudhir;
- Georgiou, Dimitra K.;
- Muller, Florian L.
Publication type:
Article
Deleterious Effect of Elevated Fatty Acid Metabolites Concentration on Skeletal Muscle Mitochondrial Atp Synthesis.
Published in:
Diabetes, 2007, v. 56, p. A337
By:
- Abdul-Ghani, Muhammad A.;
- Muller, Florian L.;
- Yuhong Liu;
- Chavez, Alberto;
- Balas, Bogdan;
- Tripathy, Devjit;
- Jani, Rucha;
- Monroy, Adriana;
- Van Remmen, Holly;
- Defronzo, Ralph A.
Publication type:
Article
The 'mitoflash' probe cpYFP does not respond to superoxide.
Published in:
Nature, 2014, v. 514, n. 7523, p. E12, doi. 10.1038/nature13858
By:
- Schwarzländer, Markus;
- Wagner, Stephan;
- Meyer, Andreas J.;
- Gems, David;
- Halestrap, Andrew P.;
- Halliwell, Barry;
- Jakob, Ursula;
- Johnston, Iain G.;
- Jones, Nick S.;
- Logan, David C.;
- Morgan, Bruce;
- Dick, Tobias P.;
- Müller, Florian L.;
- Nicholls, David G.;
- Remington, S. James;
- Ermakova, Yulia G.;
- Belousov, Vsevolod V.;
- Schumacker, Paul T.;
- Winterbourn, Christine C.;
- Murphy, Michael P.
Publication type:
Article
Passenger deletions generate therapeutic vulnerabilities in cancer.
Published in:
Nature, 2012, v. 488, n. 7411, p. 337, doi. 10.1038/nature11331
By:
- Muller, Florian L.;
- Colla, Simona;
- Aquilanti, Elisa;
- Manzo, Veronica E.;
- Genovese, Giannicola;
- Lee, Jaclyn;
- Eisenson, Daniel;
- Narurkar, Rujuta;
- Deng, Pingna;
- Nezi, Luigi;
- Lee, Michelle A.;
- Hu, Baoli;
- Hu, Jian;
- Sahin, Ergun;
- Ong, Derrick;
- Fletcher-Sananikone, Eliot;
- Ho, Dennis;
- Kwong, Lawrence;
- Brennan, Cameron;
- Wang, Y. Alan
Publication type:
Article
HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00449-z
By:
- Mbofung, Rina M.;
- McKenzie, Jodi A.;
- Malu, Shruti;
- Min Zhang;
- Weiyi Peng;
- Chengwen Liu;
- Kuiatse, Isere;
- Tieu, Trang;
- Williams, Leila;
- Devi, Seram;
- Ashkin, Emily;
- Chunyu Xu;
- Lu Huang;
- Minying Zhang;
- Talukder, Amjad H.;
- Tripathi, Satyendra C.;
- Hiep Khong;
- Satani, Nikunj;
- Muller, Florian L.;
- Roszik, Jason
Publication type:
Article
The 3S Enantiomer Drives Enolase Inhibitory Activity in SF2312 and Its Analogues.
Published in:
Molecules, 2019, v. 24, n. 13, p. 2510, doi. 10.3390/molecules24132510
By:
- Pisaneschi, Federica;
- Lin, Yu-Hsi;
- Leonard, Paul G.;
- Satani, Nikunj;
- Yan, Victoria C.;
- Hammoudi, Naima;
- Raghavan, Sudhir;
- Link, Todd M.;
- K. Georgiou, Dimitra;
- Czako, Barbara;
- Muller, Florian L.;
- Miyata, Yasuyoshi;
- Kokotos, George
Publication type:
Article
FOXO protects against age‐progressive axonal degeneration.
Published in:
Aging Cell, 2018, v. 17, n. 1, p. 1, doi. 10.1111/acel.12701
By:
- Hwang, Inah;
- Oh, Hwanhee;
- Santo, Evan;
- Kim, Do‐Yeon;
- Chen, John W.;
- Bronson, Roderick T.;
- Locasale, Jason W.;
- Na, Yoonmi;
- Lee, Jaclyn;
- Reed, Stewart;
- Toth, Miklos;
- Yu, Wai H.;
- Muller, Florian L.;
- Paik, Jihye
Publication type:
Article
Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD.
Published in:
Aging Cell, 2012, v. 11, n. 5, p. 770, doi. 10.1111/j.1474-9726.2012.00843.x
By:
- Jang, Young C.;
- Liu, Yuhong;
- Hayworth, Christopher R.;
- Bhattacharya, Arunabh;
- Lustgarten, Michael S.;
- Muller, Florian L.;
- Chaudhuri, Asish;
- Qi, Wenbo;
- Li, Yan;
- Huang, Jing-Yi;
- Verdin, Eric;
- Richardson, Arlan;
- Van Remmen, Holly
Publication type:
Article
MnSOD deficiency results in elevated oxidative stress and decreased mitochondrial function but does not lead to muscle atrophy during aging.
Published in:
Aging Cell, 2011, v. 10, n. 3, p. 493, doi. 10.1111/j.1474-9726.2011.00695.x
By:
- Lustgarten, Michael S.;
- Jang, Youngmok C.;
- Liu, Yuhong;
- Qi, Wenbo;
- Qin, Yuejuan;
- Dahia, Patricia L.;
- Shi, Yun;
- Bhattacharya, Arunabh;
- Muller, Florian L.;
- Shimizu, Takahiko;
- Shirasawa, Takuji;
- Richardson, Arlan;
- Van Remmen, Holly
Publication type:
Article

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