Works matching AU Muir, Tom

Results: 73

Tuning protein autoinhibition by domain destabilization.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 5, p. 550, doi. 10.1038/nsmb.2039

By:

Jae-Hyun Cho;
Muralidharan, Vasant;
Vila-Perello, Miquel;
Raleigh, Daniel P.;
Muir, Tom W.;
Palmer, Arthur G.

Publication type:

Article

Targeted Histone Peptides: Insights into the Spatial Regulation of the Methyltransferase PRC2 by using a Surrogate of Heterotypic Chromatin.

Published in:

Angewandte Chemie, 2015, v. 127, n. 22, p. 6557, doi. 10.1002/ange.201500085

By:

Brown, Zachary Z.;
Müller, Manuel M.;
Kong, Ha Eun;
Lewis, Peter W.;
Muir, Tom W.

Publication type:

Article

Kinetic Control of One-Pot Trans-Splicing Reactions by Using a Wild-Type and Designed Split Intein.

Published in:

Angewandte Chemie, 2011, v. 123, n. 29, p. 6641, doi. 10.1002/ange.201102909

By:

Shah, Neel H.;
Vila-Perelló, Miquel;
Muir, Tom W.

Publication type:

Article

An amalgamation of solid phase peptide synthesis and ribosomal peptide synthesis.

Published in:

Biopolymers, 2008, v. 90, n. 3, p. 406, doi. 10.1002/bip.20810

By:

Ottesen, Jennifer J.;
Bar-Dagan, Maya;
Giovani, Baldissera;
Muir, Tom W.

Publication type:

Article

Studying protein structure and function using semisynthesis.

Published in:

Biopolymers, 2008, v. 90, n. 6, p. 743, doi. 10.1002/bip.21102

By:

Muir, Tom W.

Publication type:

Article

Activation of Protein Splicing by Protease- or Light-Triggered O to N Acyl Migration.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 40, p. 7764, doi. 10.1002/anie.200802502

By:

Vila-Perelló, Miquel;
Hori, Yuichiro;
Ribó, Marc;
Muir, Tom W.

Publication type:

Article

Auxiliary-Mediated Site-Specific Peptide Ubiquitylation.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 16, p. 2814, doi. 10.1002/anie.200605155

By:

Chatterjee, Champak;
McGinty, Robert K.;
Pellois, Jean-Philippe;
Muir, Tom W.

Publication type:

Article

A Ligation and Photorelease Strategy for the Temporal and Spatial Control of Protein Function in Living CellsWe gratefully acknowledge Dr. Alison North for her assistance at the bio-imaging center of The Rockefeller University. We thank Dr. Jianxin Shi, Edmund Schwartz, and Amy Tyszkiewicz for help with cloning procedures. This work was supported by NIH grant GM55843-07.

Published in:

Angewandte Chemie International Edition, 2005, v. 44, n. 35, p. 5713, doi. 10.1002/anie.200501244

By:

Jean-Philippe Pellois;
Tom W. Muir

Publication type:

Article

Photocontrol of Smad2, a Multiphosphorylated Cell-Signaling Protein, through Caging of Activating PhosphoserinesWe gratefully acknowledge Dr. Jean-Philippe Pellois, Dr. Jennifer Ottesen, and Edmund Schwartz for valuable discussions. We thank Claudio Alarcón and Prof. Joan Massagué for help with the nuclear import assay and Dr. Júlio César-Padovan and Prof. Brian Chait for MS/MS measurements. This work was supported by NIH grants CGM55843–07 and EB001991 (to T.W.M.). M.E.H. was supported by the NIH Medical Scientist Training Program grant GM07739.

Published in:

Angewandte Chemie International Edition, 2004, v. 43, n. 43, p. 5800, doi. 10.1002/anie.200461141

By:

Michael E. Hahn;
Tom W. Muir

Publication type:

Article

Activation of an Autoregulated Protein Kinase by Conditional Protein SplicingWe would like to thank the members of the Muir laboratory and Jörn Lausen for technical and scientific advice during the course of this work. This work was supported by a National Institutes of Health grant awarded to T.W.M. (Grant no. R01-GM59908).

Published in:

Angewandte Chemie International Edition, 2004, v. 43, n. 39, p. 5189, doi. 10.1002/anie.200460941

By:

Henning D. Mootz;
Elyse S. Blum;
Tom W. Muir

Publication type:

Article

Semisynthesis of a Functional K<sup>+</sup> Channel ( We gratefully acknowledge the assistance provided by Dr. M. Zhou in the collection and analysis of electrophysiological data. This work was supported by the Howard Hughes Medical Institute and National Institutes of Health. )

Published in:

Angewandte Chemie International Edition, 2004, v. 43, n. 19, p. 2504

By:

Francis I. Valiyaveetil;
Matthew Sekedat;
Tom W. Muir;
Roderick MacKinnon

Publication type:

Article

Introduction of unnatural amino acids into proteins using expressed protein ligation.

Published in:

Biopolymers, 1999, v. 51, n. 5, p. 343, doi. 10.1002/(SICI)1097-0282(1999)51:5<343::AID-BIP4>3.0.CO;2-W

By:

Ayers, Brenda;
Blaschke, Ulrich K.;
Camarero, Julio A.;
Cotton, Graham J.;
Holford, Mande;
Muir, Tom W.

Publication type:

Article

And be but cryonically extant: Don DeLillo and Sir Thomas Browne.

Published in:

Textual Practice, 2023, v. 37, n. 3, p. 435, doi. 10.1080/0950236X.2022.2056235

By:

Muir, Tom

Publication type:

Article

Symmetric signalling within asymmetric dimers of the Staphylococcus aureus receptor histidine kinase AgrC.

Published in:

Molecular Microbiology, 2009, v. 74, n. 1, p. 44, doi. 10.1111/j.1365-2958.2009.06849.x

By:

Cisar, Elizabeth A. George;
Geisinger, Edward;
Muir, Tom W.;
Novick, Richard P.

Publication type:

Article

Systems- and Molecular-Level Elucidation of Signaling Processes Through Chemistry.

Published in:

Science Signaling, 2008, v. 1, n. 42, p. 1, doi. 10.1126/scisignal.142pe45

By:

Chiang, Kyle P.;
Muir, Tom W.

Publication type:

Article

Without remainder: ruins and tombs in Shakespeare's Sonnets.

Published in:

2010

By:

Muir, Tom

Publication type:

Literary Criticism

ARTICLE Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03895-5

By:

Wojcik, Felix;
Muir, Tom W.;
Dann, Geoffrey P.;
Beh, Leslie Y.;
Debelouchina, Galia T.;
Hofmann, Raphael

Publication type:

Article

Histone H3K27 Trimethylation Inhibits H3 Binding and Function of SET1-Like H3K4 Methyltransferase Complexes.

Published in:

Molecular & Cellular Biology, 2013, v. 33, n. 24, p. 4936, doi. 10.1128/MCB.00601-13

By:

Dae-Hwan Kim;
Zhanyun Tang;
Miho Shimada;
Fierz, Beat;
Houck-Loomis, Brian;
Bar-Dagen, Maya;
Seunghee Lee;
Soo-Kyung Lee;
Muir, Tom W.;
Roeder, Robert G.;
Jae W. Lee

Publication type:

Article

Tunable Photoactivation of a Post-translationally Modified Signaling Protein and its Unmodified Counterpart in Live Cells.

Published in:

ChemBioChem, 2007, v. 8, n. 17, p. 2100, doi. 10.1002/cbic.200700404

By:

Hahn, Michael E.;
Pellois, Jean-Philippe;
Vila-Perelló, Miquel;
Muir, Tom W.

Publication type:

Article

Molecular Mechanisms of agr Quorum Sensing in Virulent Staphylococci.

Published in:

ChemBioChem, 2007, v. 8, n. 8, p. 847, doi. 10.1002/cbic.200700023

By:

George, Elizabeth A.;
Muir, Tom W.

Publication type:

Article

Posttranslational Modification of Proteins: Expanding Nature's Inventory. By Christopher T. Walsh.

Published in:

ChemBioChem, 2006, v. 7, n. 10, p. 1623, doi. 10.1002/cbic.200600342

By:

Tom Muir

Publication type:

Article

Activation of the focal adhesion kinase signaling pathway by structural alterations in the carboxyl-terminal region of c-Crk II.

Published in:

Oncogene, 2001, v. 20, n. 8, p. 951, doi. 10.1038/sj.onc.1204173

By:

Zvara, Agnes;
Fajardo, J Eduardo;
Escalante, Marcela;
Cotton, Graham;
Muir, Tom;
Kirsch, Kathrin H;
Birge, Raymond B

Publication type:

Article

Turning virulence on and off in Staphylococci.

Published in:

Journal of Peptide Science, 2003, v. 9, n. 10, p. 612, doi. 10.1002/psc.486

By:

Tom W. Muir

Publication type:

Article

A molecular engineering toolbox for the structural biologist.

Published in:

Quarterly Reviews of Biophysics, 2017, v. 50, p. 1, doi. 10.1017/S0033583517000051

By:

Debelouchina, Galia T.;
Muir, Tom W.

Publication type:

Article

Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralization.

Published in:

EMBO Journal, 1997, v. 16, n. 6, p. 1189, doi. 10.1093/emboj/16.6.1189

By:

Stewart, Phoebe L.;
Chiu, Charles Y.;
Shuang Huang;
Muir, Tom;
Yingming Zhao;
Chait, Brian;
Mathias, Patricia;
Nemerow, Glen R.

Publication type:

Article

Determination of safe levels of persistent organic pollutants in toxicology and epidemiology.

Published in:

Reviews on Environmental Health, 2023, v. 38, n. 3, p. 401, doi. 10.1515/reveh-2021-0105

By:

Muir, Tom;
Michalek, Joel E;
Palmer, Raymond F

Publication type:

Article

‘And thou shall find your path’: The Manifesto in Doctoral Writing Development.

Published in:

Journal of Academic Writing, 2022, v. 12, n. 1, p. 68, doi. 10.18552/joaw.v12i1.817

By:

Muir, Tom;
Solli, Kristin

Publication type:

Article

Writing and Risk: Magic, Occult, Exorcisms.

Published in:

Journal of Academic Writing, 2018, v. 8, n. 2, p. 212, doi. 10.18552/joaw.v8i2.484

By:

Muir, Tom

Publication type:

Article

Split Inteins: Nature's Protein Ligases.

Published in:

Israel Journal of Chemistry, 2011, v. 51, n. 8/9, p. 854, doi. 10.1002/ijch.201100094

By:

Shah, Neel H.;
Muir, Tom W.

Publication type:

Article

Toward Fully Synthetic N-Linked Glycoproteins.

Published in:

Angewandte Chemie International Edition, 2003, v. 42, n. 4, p. 431, doi. 10.1002/anie.200390131

By:

Miller, Justin S.;
Dudkin, Vadim Y.;
Lyon, Gholson J.;
Muir, Tom W.;
Danishefsky, Samuel J.

Publication type:

Article

Chemical Synthesis of a Circular Protein Domain: Evidence for Folding-Assisted Cyclization.

Published in:

Angewandte Chemie International Edition, 1998, v. 37, n. 3, p. 347, doi. 10.1002/(SICI)1521-3773(19980216)37:3<347::AID-ANIE347>3.0.CO;2-5

By:

Camarero, Julio A.;
Pavel, Joanna;
Muir, Tom W.

Publication type:

Article

Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries.

Published in:

Nature Methods, 2014, v. 11, n. 8, p. 834, doi. 10.1038/nmeth.3022

By:

Nguyen, Uyen T T;
Bittova, Lenka;
Müller, Manuel M;
Fierz, Beat;
David, Yael;
Houck-Loomis, Brian;
Feng, Vanessa;
Dann, Geoffrey P;
Muir, Tom W

Publication type:

Article

Activation of protein splicing with light in yeast.

Published in:

Nature Methods, 2008, v. 5, n. 4, p. 303, doi. 10.1038/nmeth.1189

By:

Tyszkiewicz, Amy B.;
Muir, Tom W.

Publication type:

Article

Protein ligation: an enabling technology for the biophysical analysis of proteins.

Published in:

Nature Methods, 2006, v. 3, n. 6, p. 429, doi. 10.1038/nmeth886

By:

Muralidharan, Vasant;
Muir, Tom W.

Publication type:

Article

Engineering of a Peptide α‐N‐Methyltransferase to Methylate Non‐Proteinogenic Amino Acids.

Published in:

Angewandte Chemie, 2021, v. 133, n. 26, p. 14440, doi. 10.1002/ange.202100818

By:

Song, Haigang;
Burton, Antony J.;
Shirran, Sally L.;
Fahrig‐Kamarauskaitė, Jūratė;
Kaspar, Hannelore;
Muir, Tom W.;
Künzler, Markus;
Naismith, James H.

Publication type:

Article

Barcoding mit Nukleinsäuren: Anwendung der DNA‐Sequenzierung als molekulares Zählwerk.

Published in:

Angewandte Chemie, 2019, v. 131, n. 13, p. 4188, doi. 10.1002/ange.201808956

By:

Liszczak, Glen;
Muir, Tom W.

Publication type:

Article

H2B ubiquitylation enhances H3K4 methylation activities of human KMT2 family complexes.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 10, p. 5442, doi. 10.1093/nar/gkaa317

By:

Kwon, Minjung;
Park, Kihyun;
Hyun, Kwangbeom;
Lee, Jeong-Heon;
Zhou, Linjiao;
Cho, Young-Wook;
Ge, Kai;
Skalnik, David G;
Muir, Tom W;
Kim, Jaehoon

Publication type:

Article

Crosstalk among Set1 complex subunits involved in H2B ubiquitylation-dependent H3K4 methylation.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 21, p. 11129, doi. 10.1093/nar/gky920

By:

Jeon, Jongcheol;
McGinty, Robert K;
Muir, Tom W;
Kim, Jung-Ae;
Kim, Jaehoon

Publication type:

Article

Long-term hepatitis B infection in a scalable hepatic co-culture system.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00200-8

By:

Winer, Benjamin Y.;
Huang, Tiffany S.;
Pludwinski, Eitan;
Heller, Brigitte;
Wojcik, Felix;
Lipkowitz, Gabriel E.;
Parekh, Amit;
Cheul Cho;
Shrirao, Anil;
Muir, Tom W.;
Novik, Eric;
Ploss, Alexander

Publication type:

Article

Evidence that ubiquitylated H2B corrals hDot1L on the nucleosomal surface to induce H3K79 methylation.

Published in:

Nature Communications, 2016, v. 7, n. 2, p. 10589, doi. 10.1038/ncomms10589

By:

Zhou, Linjiao;
Holt, Matthew T.;
Ohashi, Nami;
Zhao, Aishan;
Müller, Manuel M.;
Wang, Boyuan;
Muir, Tom W.

Publication type:

Article

A pan-specific antibody for direct detection of protein histidine phosphorylation.

Published in:

Nature Chemical Biology, 2013, v. 9, n. 7, p. 416, doi. 10.1038/nchembio.1259

By:

Kee, Jung-Min;
Oslund, Rob C;
Perlman, David H;
Muir, Tom W

Publication type:

Article

Induction of innate and adaptive immunity by delivery of poly dA:dT to dendritic cells.

Published in:

Nature Chemical Biology, 2013, v. 9, n. 4, p. 250, doi. 10.1038/nchembio.1186

By:

Barbuto, Scott;
Idoyaga, Juliana;
Vila-Perelló, Miquel;
Longhi, Maria P;
Breton, Gaëlle;
Steinman, Ralph M;
Muir, Tom W

Publication type:

Article

Chromatin as an expansive canvas for chemical biology.

Published in:

Nature Chemical Biology, 2012, v. 8, n. 5, p. 417, doi. 10.1038/nchembio.938

By:

Fierz, Beat;
Muir, Tom W

Publication type:

Article

Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction.

Published in:

Nature Chemical Biology, 2011, v. 7, n. 2, p. 113, doi. 10.1038/nchembio.501

By:

Fierz, Beat;
Chatterjee, Champak;
McGinty, Robert K;
Bar-Dagan, Maya;
Raleigh, Daniel P;
Muir, Tom W

Publication type:

Article

Branched intermediate formation stimulates peptide bond cleavage in protein splicing.

Published in:

Nature Chemical Biology, 2010, v. 6, n. 7, p. 527, doi. 10.1038/nchembio.371

By:

Frutos, Silvia;
Goger, Michael;
Giovani, Baldissera;
Cowburn, David;
Muir, Tom W.

Publication type:

Article

Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation.

Published in:

Nature Chemical Biology, 2010, v. 6, n. 4, p. 267, doi. 10.1038/nchembio.315

By:

Chatterjee, Champak;
McGinty, Robert K.;
Fierz, Beat;
Muir, Tom W.

Publication type:

Article

Post-translational enzyme activation in an animal via optimized conditional protein splicing.

Published in:

Nature Chemical Biology, 2007, v. 3, n. 1, p. 50, doi. 10.1038/nchembio832

By:

Schwartz, Edmund C.;
Saez, Lino;
Young, Michael W.;
Muir, Tom W.

Publication type:

Article

Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB.

Published in:

Nature, 2010, v. 465, n. 7295, p. 243, doi. 10.1038/nature08966

By:

Scheuermann, Johanna C.;
de Ayala Alonso, Andrés Gaytán;
Oktaba, Katarzyna;
Nga Ly-Hartig;
McGinty, Robert K.;
Fraterman, Sven;
Wilm, Matthias;
Muir, Tom W.;
Müller, Jürg

Publication type:

Article

Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation.

Published in:

2008

By:

McGinty, Robert K.;
Jaehoon Kim;
Chatterjee, Champak;
Roeder, Robert G.;
Muir, Tom W.

Publication type:

Letter

Chemical biology: Cutting out the middle man.

Published in:

Nature, 2006, v. 442, n. 7102, p. 517, doi. 10.1038/442517a

By:

Muir, Tom W.

Publication type:

Article