Works by Muanprasat, Chatchai

Results: 56

Identification of novel TMEM16A blockers through integrated virtual screening, molecular dynamics, and experimental studies.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-99751-w

By:

Sangkhawasi, Mattanun;
Pitaktrakul, Wichuda;
Khumjiang, Rungtiwa;
Shigeta, Yasuteru;
Muanprasat, Chatchai;
Hengphasatporn, Kowit;
Rungrotmongkol, Thanyada

Publication type:

Article

Chitosan Oligosaccharide Ameliorates Kidney Injury by Improving Intestinal Barrier Dysfunction and Lipid Metabolism in Obese‐insulin Resistant Rats.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.0R803

By:

Sutthasupha, Prempree;
Promsan, Sasivimon;
Phengpol, Nichakorn;
Pichyangkura, Rath;
Muanprasat, Chatchai;
Lungkaphin, Anusorn

Publication type:

Article

Effects of Fungus‐Derived Compound N9 on Airway Mucus Secretion: In Vitro and In Vivo Studies.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R1976

By:

Yimnual, Chantapol;
Worakajit, Nichakorn;
Kaewin, Suchada;
Rukachaisirikul, Vatcharin;
Muanprasat, Chatchai

Publication type:

Article

Discovery of a Fungal Metabolite as a Novel TMEM16a Inhibitor in Human Airway Epithelial Cells.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R3278

By:

Pongkorpsakol, Pawin;
Satianrapapong, Wilasinee;
Muanprasat, Chatchai

Publication type:

Article

Identification of Fungus‐derived Compounds as a Novel CFTR inhibitor: Mechanism and Potential Anti‐diarrheal Application.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2169

By:

Noitem, Rattikarn;
Pongkorpsakol, Pawin;
Changsen, Chartchai;
Rukachaisirikul, Vatcharin;
Muanprasat, Chatchai

Publication type:

Article

A novel compound AD021 attenuates renal fibrosis by inhibiting transforming growth factor‐β1 in renal proximal tubule epithelial cells.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2316

By:

Poolsri, Wanangkan;
Jutabha, Promsuk;
Chavasiri, Warinthorn;
Muanprasat, Chatchai

Publication type:

Article

Coumarins and flavones from the fruit and root extracts of Micromelum integerrimum.

Published in:

Natural Product Research, 2019, v. 33, n. 20, p. 2945, doi. 10.1080/14786419.2018.1510400

By:

Suthiphasilp, Virayu;
Maneerat, Wisanu;
Andersen, Raymond J.;
Pyne, Stephen G.;
Muanprasat, Chatchai;
Seemakhan, Sawinee;
Borwornpinyo, Suparerk;
Laphookhieo, Surat

Publication type:

Article

Galactomannan Pentasaccharide Produced from Copra Meal Enhances Tight Junction Integration of Epithelial Tissue through Activation of AMPK.

Published in:

Biomedicines, 2019, v. 7, n. 4, p. 81, doi. 10.3390/biomedicines7040081

By:

Nopvichai, Chatchai;
Pongkorpsakol, Pawin;
Wongkrasant, Preedajit;
Wangpaiboon, Karan;
Charoenwongpaiboon, Thanapon;
Ito, Kazuo;
Muanprasat, Chatchai;
Pichyangkura, Rath

Publication type:

Article

Potential Applications of Chitosan-Based Nanomaterials to Surpass the Gastrointestinal Physiological Obstacles and Enhance the Intestinal Drug Absorption.

Published in:

Pharmaceutics, 2021, v. 13, n. 6, p. 887, doi. 10.3390/pharmaceutics13060887

By:

Pathomthongtaweechai, Nutthapoom;
Muanprasat, Chatchai

Publication type:

Article

Cholesterol-Lowering Effects of Asperidine B, a Pyrrolidine Derivative from the Soil-Derived Fungus Aspergillus sclerotiorum PSU-RSPG178: A Potential Cholesterol Absorption Inhibitor.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 8, p. 955, doi. 10.3390/ph15080955

By:

Ontawong, Atcharaporn;
Duangjai, Acharaporn;
Sukpondma, Yaowapa;
Tadpetch, Kwanruthai;
Muanprasat, Chatchai;
Rukachaisirikul, Vatcharin;
Inchai, Jakkapong;
Vaddhanaphuti, Chutima S.

Publication type:

Article

High-Efficacy α,β-Dehydromonacolin S Improves Hepatic Steatosis and Suppresses Gluconeogenesis Pathway in High-Fat Diet-Induced Obese Rats.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 4, p. 375, doi. 10.3390/ph14040375

By:

Kaewmalee, Jutatip;
Ontawong, Atcharaporn;
Duangjai, Acharaporn;
Tansakul, Chittreeya;
Rukachaisirikul, Vatcharin;
Muanprasat, Chatchai;
Srimaroeng, Chutima

Publication type:

Article

Inhibition of cAMP-Activated Intestinal Chloride Secretion by Diclofenac: Cellular Mechanism and Potential Application in Cholera.

Published in:

PLoS Neglected Tropical Diseases, 2014, v. 8, n. 9, p. 1, doi. 10.1371/journal.pntd.0003119

By:

Pongkorpsakol, Pawin;
Pathomthongtaweechai, Nutthapoom;
Srimanote, Potjanee;
Soodvilai, Sunhapas;
Chatsudthipong, Varanuj;
Muanprasat, Chatchai

Publication type:

Article

Inhibition of cAMP-Activated Intestinal Chloride Secretion by Diclofenac: Cellular Mechanism and Potential Application in Cholera.

Published in:

PLoS Neglected Tropical Diseases, 2014, v. 8, n. 9, p. 1, doi. 10.1371/journal.pntd.0003119

By:

Pongkorpsakol, Pawin;
Pathomthongtaweechai, Nutthapoom;
Srimanote, Potjanee;
Soodvilai, Sunhapas;
Chatsudthipong, Varanuj;
Muanprasat, Chatchai

Publication type:

Article

An Adult Mouse Model of Vibrio cholerae-induced Diarrhea for Studying Pathogenesis and Potential Therapy of Cholera.

Published in:

PLoS Neglected Tropical Diseases, 2013, v. 7, n. 6, p. 1, doi. 10.1371/journal.pntd.0002293

By:

Sawasvirojwong, Sutthipong;
Srimanote, Potjanee;
Chatsudthipong, Varanuj;
Muanprasat, Chatchai

Publication type:

Article

An Adult Mouse Model of <i>Vibrio cholerae</i>-induced Diarrhea for Studying Pathogenesis and Potential Therapy of Cholera.

Published in:

PLoS Neglected Tropical Diseases, 2013, v. 7, n. 6, p. 1, doi. 10.1371/journal.pntd.0002293

By:

Sawasvirojwong, Sutthipong;
Srimanote, Potjanee;
Chatsudthipong, Varanuj;
Muanprasat, Chatchai

Publication type:

Article

Talarostatin, a vermistatin derivative from the soil-derived fungus Talaromyces thailandensis PSU-SPSF059.

Published in:

Natural Product Research, 2024, v. 38, n. 15, p. 2535, doi. 10.1080/14786419.2023.2188209

By:

Ningsih, Baiq Nila Sari;
Rukachaisirikul, Vatcharin;
Phongpaichit, Souwalak;
Muanprasat, Chatchai;
Preedanon, Sita;
Sakayaroj, Jariya;
Intayot, Ratchadaree;
Jungsuttiwong, Siriporn

Publication type:

Article

Furanone, morpholinone and tetrahydrofuran derivatives from the marine-derived fungus Talaromyces sp. PSU-MF07.

Published in:

Natural Product Research, 2023, v. 37, n. 20, p. 3434, doi. 10.1080/14786419.2022.2079124

By:

Nuansri, Sucheewin;
Rukachaisirikul, Vatcharin;
Muanprasat, Chatchai;
Phongpaichit, Souwalak;
Preedanon, Sita;
Sakayaroj, Jariya

Publication type:

Article

A nonadride derivative from the marine-derived fungus Aspergillus chevalieri PSU-AMF79.

Published in:

Natural Product Research, 2023, v. 37, n. 14, p. 2311, doi. 10.1080/14786419.2022.2039651

By:

Ningsih, Baiq Nila Sari;
Rukachaisirikul, Vatcharin;
Phongpaichit, Souwalak;
Preedanon, Sita;
Sakayaroj, Jariya;
Muanprasat, Chatchai

Publication type:

Article

α-Pyrone and decalin derivatives from the marine-derived fungus Trichoderma harzianum PSU-MF79.

Published in:

Natural Product Research, 2022, v. 36, n. 21, p. 5462, doi. 10.1080/14786419.2021.2015593

By:

Nuansri, Sucheewin;
Rukachaisirikul, Vatcharin;
Rungwirain, Narate;
Kaewin, Suchada;
Yimnual, Chantapol;
Phongpaichit, Souwalak;
Preedanon, Sita;
Sakayaroj, Jariya;
Muanprasat, Chatchai

Publication type:

Article

AMPK in Intestinal Health and Disease: A Multifaceted Therapeutic Target for Metabolic and Inflammatory Disorders.

Published in:

Drug Design, Development & Therapy, 2025, v. 19, p. 3029, doi. 10.2147/DDDT.S507489

By:

Yibcharoenporn, Chamnan;
Muanprasat, Chatchai;
Moonwiriyakit, Aekkacha;
Satitsri, Saravut;
Pathomthongtaweechai, Nutthapoom

Publication type:

Article

Adenosine monophosphate-activated protein kinase activation and suppression of inflammatory response by cell stretching in rabbit synovial fibroblasts.

Published in:

Molecular & Cellular Biochemistry, 2016, v. 423, n. 1/2, p. 175, doi. 10.1007/s11010-016-2835-6

By:

Kunanusornchai, Wanlop;
Muanprasat, Chatchai;
Chatsudthipong, Varanuj

Publication type:

Article

Pathophysiological mechanisms of diarrhea caused by the Vibrio cholerae O1 El Tor variant: an in vivo study in mice.

Published in:

Virulence, 2016, v. 7, n. 7, p. 789, doi. 10.1080/21505594.2016.1192743

By:

Satitsri, Saravut;
Pongkorpsakol, Pawin;
Srimanote, Potjanee;
Chatsudthipong, Varanuj;
Muanprasat, Chatchai

Publication type:

Article

A Plant-Derived Hydrolysable Tannin Inhibits CFTR Chloride Channel: A Potential Treatment of Diarrhea.

Published in:

Pharmaceutical Research, 2010, v. 27, n. 3, p. 490, doi. 10.1007/s11095-009-0040-y

By:

Wongsamitkul, Nisa;
Sirianant, Lalida;
Muanprasat, Chatchai;
Chatsudthipong, Varanuj

Publication type:

Article

Antidiarrheal efficacy of a quinazolin CFTR inhibitor on human intestinal epithelial cell and in mouse model of cholera.

Published in:

Indian Journal of Pharmacology, 2012, v. 44, n. 5, p. 619, doi. 10.4103/0253-7613.100392

By:

Jenvit Patanayindee;
Muanprasat, Chatchai;
Soodvilai, Sunhapas;
Chatsudthipong, Varanuj

Publication type:

Article

A chalcone derivative retards renal cyst enlargement by inhibiting fluid secretion and cell proliferation in an in vitro model of polycystic kidney disease.

Published in:

Clinical & Experimental Nephrology, 2021, v. 25, n. 9, p. 944, doi. 10.1007/s10157-021-02080-1

By:

Veeraphan, Peerachat;
Chavasiri, Warinthorn;
Muanprasat, Chatchai;
Chatsudthipong, Varanuj;
Yuajit, Chaowalit

Publication type:

Article

Holy Basil (Ocimum sanctum L.) Flower and Fenofibrate Improve Lipid Profiles in Rats with Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD): The Role of Choline Metabolism.

Published in:

Plants (2223-7747), 2025, v. 14, n. 1, p. 13, doi. 10.3390/plants14010013

By:

Taesuwan, Siraphat;
Inchai, Jakkapong;
Boonyingsathit, Konpong;
Chimkerd, Chanika;
Judprasong, Kunchit;
Rachtanapun, Pornchai;
Muanprasat, Chatchai;
Vaddhanaphuti, Chutima S.

Publication type:

Article

Natural statin derivatives as potential therapy to reduce intestinal fluid loss in cholera.

Published in:

PLoS Neglected Tropical Diseases, 2022, v. 16, n. 12, p. 1, doi. 10.1371/journal.pntd.0010989

By:

Noitem, Rattikarn;
Pongkorpsakol, Pawin;
Changsen, Chartchai;
Sukpondma, Yaowapa;
Tansakul, Chittreeya;
Rukachaisirikul, Vatcharin;
Muanprasat, Chatchai

Publication type:

Article

Inhibition of CFTR-mediated intestinal chloride secretion by nornidulin: Cellular mechanisms and anti-secretory efficacy in human intestinal epithelial cells and human colonoids.

Published in:

PLoS ONE, 2024, v. 19, n. 12, p. 1, doi. 10.1371/journal.pone.0314723

By:

Yibcharoenporn, Chamnan;
Kongkaew, Thidarat;
Worakajit, Nichakorn;
Khumjiang, Rungtiwa;
Saetang, Praphatsorn;
Satitsri, Saravut;
Rukachaisirikul, Vatcharin;
Muanprasat, Chatchai

Publication type:

Article

Neuroprotective effect of short‐chain fatty acids against oxidative stress‐induced SH‐SY5Y injury via GPR43‐dependent pathway.

Published in:

Journal of Neurochemistry, 2023, v. 166, n. 2, p. 201, doi. 10.1111/jnc.15827

By:

Saikachain, Nongluk;
Sungkaworn, Titiwat;
Muanprasat, Chatchai;
Asavapanumas, Nithi

Publication type:

Article

Total Synthesis and Biological Evaluation of Seiricuprolide and Pestalotioprolide B.

Published in:

European Journal of Organic Chemistry, 2023, v. 26, n. 13, p. 1, doi. 10.1002/ejoc.202300034

By:

Sanphetchaloemchok, Pitipat;
Saikachain, Nongluk;
Khumjiang, Rungtiwa;
Muanprasat, Chatchai;
Tadpetch, Kwanruthai

Publication type:

Article

Production and purification of mannan oligosaccharide with epithelial tight junction enhancing activity.

Published in:

PeerJ, 2019, p. 1, doi. 10.7717/peerj.7206

By:

Nopvichai, Chatchai;
Charoenwongpaiboon, Thanapon;
Luengluepunya, Navaporn;
Kazuo Ito;
Muanprasat, Chatchai;
, Rath Pichyangkura

Publication type:

Article

Total Synthesis and Biological Evaluation of Mutolide and Analogues.

Published in:

Chemistry - An Asian Journal, 2022, v. 17, n. 16, p. 1, doi. 10.1002/asia.202200329

By:

Thiraporn, Aticha;
Saikachain, Nongluk;
Khumjiang, Rungtiwa;
Muanprasat, Chatchai;
Tadpetch, Kwanruthai

Publication type:

Article

The barrier-protective effect of β-eudesmol against type 2-inflammatory cytokine-induced tight junction disassembly in airway epithelial cells.

Published in:

PLoS ONE, 2024, v. 19, n. 4, p. 1, doi. 10.1371/journal.pone.0302851

By:

Tharabenjasin, Phuntila;
Moonwiriyakit, Aekkacha;
Sontikun, Jenjira;
Timpratueang, Kanokphorn;
Kuno, Suhaibee;
Aiebchun, Thitinan;
Jongkon, Nathjanan;
Mongkolrob, Rungrawee;
Pabalan, Noel;
Choowongkomon, Kiattawee;
Muanprasat, Chatchai

Publication type:

Article

Solanum melongena L. Extract Promotes Intestinal Tight Junction Re‐Assembly via SIRT‐1‐Dependent Mechanisms.

Published in:

Molecular Nutrition & Food Research, 2024, v. 68, n. 16, p. 1, doi. 10.1002/mnfr.202400230

By:

Sukmak, Pichayapa;
Kulworasreth, Purisha;
Treveeravoot, Supisara;
Arinno, Apiwan;
Anuwongworavet, Supitcha;
Wachiradejkul, Wanapas;
Kulworasreth, Purit;
Teansuk, Natnicha;
Thongnak, Laongdao;
Amonlerdpison, Doungporn;
Inchai, Jakkapong;
Jakrachai, Chaiwet;
Akrimajirachoote, Nattaphong;
Aonbangkhen, Chanat;
Muanprasat, Chatchai;
Poolsri, Wanangkan;
Vaddhanaphuti, Chutima S.;
Pongkorpsakol, Pawin

Publication type:

Article

Piperine as potential therapy of post-weaning porcine diarrheas: an in vitro study using a porcine duodenal enteroid model.

Published in:

BMC Veterinary Research, 2023, v. 19, n. 1, p. 1, doi. 10.1186/s12917-022-03536-6

By:

Satitsri, Saravut;
Akrimajirachoote, Nattaphong;
Nunta, Kanokkan;
Ruennarong, Nitwarat;
Amnucksoradej, Orawan;
Muanprasat, Chatchai

Publication type:

Article

Anti‐asthmatic drug pranlukast attenuates cyst progression in an MDCK cyst model (690.4).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.690.4

By:

Pathomthongtaweechai, Nutthapoom;
Chatsudthipong, Varanuj;
Muanprasat, Chatchai

Publication type:

Article

Steviol retards renal cyst growth through reduction of CFTR expression and inhibition of epithelial cell proliferation in a mouse model of polycystic kidney disease (690.2).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.690.2

By:

Chatsudthipong, Varanuj;
Yuajit, Chaowalit;
Muanprasat, Chatchai;
Kittayaruksakul, Suticha;
Fedeles, Sorin;
Gallagher, Anna‐Rachel;
Somlo, Stefan

Publication type:

Article

Inhibition of renal cyst progression by montelukast: an in vitro study in MDCK cells.

Published in:

FASEB Journal, 2013, v. 27, p. 912.1, doi. 10.1096/fasebj.27.1_supplement.912.1

By:

Pathomthongtaweechai, Nutthapoom;
Chatsudthipong, Varanuj;
Muanprasat, Chatchai

Publication type:

Article

Steviol retards cyst growth through inhibition of ERK and wnt/β‐catenin pathways.

Published in:

FASEB Journal, 2013, v. 27, p. 705.2, doi. 10.1096/fasebj.27.1_supplement.705.2

By:

Yuajit, Chaowalit;
Nantavishit, Jiriporn;
Muanprasat, Chatchai;
Chatsudthipong, Varanuj

Publication type:

Article

Luminally active, nonabsorbable CFTR inhibitors as potential therapy to reduce intestinal fluid loss in cholera.

Published in:

FASEB Journal, 2006, v. 20, n. 1, p. 130, doi. 10.1096/fj.05-4818fje

By:

Sonawane, N. D.;
Jie Hu;
Muanprasat, Chatchai;
Verkman, A. S.

Publication type:

Article

Sequence and Apoptotic Activity of VacA Cytotoxin Cloned from a Helicobacter pylori Thai Clinical Isolate.

Published in:

2014

By:

Junaid, Muhammad;
Al-Gubare, Sarbast;
Yousef, Muhammad;
Na Ubol, Mathukorn;
Leetachewa, Somphob;
Muanprasat, Chatchai;
Angsuthanasombat, Chanan;
Chaicumpa, Wanpen;
Ali, Niaz;
Katzenmeier, Gerd

Publication type:

Journal Article

Sequence and Apoptotic Activity of VacA Cytotoxin Cloned from a Helicobacter pylori Thai Clinical Isolate.

Published in:

BioMed Research International, 2014, v. 2014, p. 1, doi. 10.1155/2014/398350

By:

Junaid, Muhammad;
Sarbast Al-Gubare;
Muhammad Yousef;
Mathukorn Na Ubol;
Somphob Leetachewa;
Chatchai Muanprasat;
Chanan Angsuthanasombat;
Wanpen Chaicumpa;
Ali, Niaz;
Gerd Katzenmeier

Publication type:

Article

Chitosan Oligosaccharide Promotes Junction Barrier through Modulation of PI3K/AKT and ERK Signaling Intricate Interplay in T84 Cells.

Published in:

Polymers (20734360), 2023, v. 15, n. 7, p. 1681, doi. 10.3390/polym15071681

By:

Mehmood, Tahir;
Pichyangkura, Rath;
Muanprasat, Chatchai

Publication type:

Article

Chitosan Oligosaccharide Prevents Afatinib-Induced Barrier Disruption and Chloride Secretion through Modulation of AMPK, PI3K/AKT, and ERK Signaling in T84 Cells.

Published in:

Polymers (20734360), 2022, v. 14, n. 20, p. 4255, doi. 10.3390/polym14204255

By:

Mehmood, Tahir;
Pichyangkura, Rath;
Muanprasat, Chatchai

Publication type:

Article

Steviol Reduces MDCK Cyst Formation and Growth by Inhibiting CFTR Channel Activity and Promoting Proteasome-Mediated CFTR Degradation.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058871

By:

Yuajit, Chaowalit;
Homvisasevongsa, Sureeporn;
Chatsudthipong, Lisa;
Soodvilai, Sunhapas;
Muanprasat, Chatchai;
Chatsudthipong, Varanuj

Publication type:

Article

Protection against Oxidative Stress in Beta Thalassemia/Hemoglobin E Erythrocytes by Inhibitors of Glutathione Efflux Transporters.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0055685

By:

Muanprasat, Chatchai;
Wongborisuth, Chokdee;
Pathomthongtaweechai, Nutthapoom;
Satitsri, Saravut;
Hongeng, Suradej

Publication type:

Article

MicroRNA-451a downregulation in liraglutide-treated individuals with diabetes: A potential cardiovascular protective mechanism.

Published in:

Diabetes & Vascular Disease Research, 2024, v. 21, n. 5, p. 1, doi. 10.1177/14791641241278527

By:

Kongrat, Surachai;
Sungkaworn, Titiwat;
Muanprasat, Chatchai;
Sriphrapradang, Chutintorn;
Yingchoncharoen, Teerapat

Publication type:

Article

GPR40 receptor activation promotes tight junction assembly in airway epithelial cells via AMPK-dependent mechanisms.

Published in:

Tissue Barriers, 2018, v. 6, n. 2, p. 1, doi. 10.1080/21688370.2018.1480741

By:

Moonwiriyakit, Aekkacha;
Wattanaphichet, Panisara;
Chatsudthipong, Varanuj;
Muanprasat, Chatchai

Publication type:

Article

Inhibition of Mitochondrial Dynamics by Mitochondrial Division Inhibitor-1 Suppresses Cell Migration and Metastatic Markers in Colorectal Cancer HCT116 Cells.

Published in:

Journal of Experimental Pharmacology, 2025, v. 17, p. 143, doi. 10.2147/JEP.S510578

By:

Mehmood, Tahir;
Nasir, Qandeel;
Younis, Iqra;
Muanprasat, Chatchai

Publication type:

Article

Discovery of Fungus-Derived Nornidulin as a Novel TMEM16A Inhibitor: A Potential Therapy to Inhibit Mucus Secretion in Asthma.

Published in:

Journal of Experimental Pharmacology, 2023, v. 15, p. 449, doi. 10.2147/JEP.S427594

By:

Pongkorpsakol, Pawin;
Yimnual, Chantapol;
Satianrapapong, Wilasinee;
Worakajit, Nichakorn;
Kaewin, Suchada;
Saetang, Praphatsorn;
Rukachaisirikul, Vatcharin;
Muanprasat, Chatchai

Publication type:

Article