Works matching AU Muñoz-Torrero, Diego
Results: 120
Clock/Sleep-Dependent Learning and Memory in Male 3xTg-AD Mice at Advanced Disease Stages and Extrinsic Effects of Huprine X and the Novel Multitarget Agent AVCRI104P3.
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- Brain Sciences (2076-3425), 2021, v. 11, n. 4, p. 426, doi. 10.3390/brainsci11040426
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- Article
Huprine X Attenuates The Neurotoxicity Induced by Kainic Acid, Especially Brain Inflammation.
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- Basic & Clinical Pharmacology & Toxicology, 2018, v. 122, n. 1, p. 94, doi. 10.1111/bcpt.12852
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- Article
Interaction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases.
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- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0188-0
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- Article
Interaction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases.
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- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0188-0
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- Article
A novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer's disease exacerbated with high fat diet.
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- Cell & Bioscience, 2023, v. 13, n. 1, p. 1, doi. 10.1186/s13578-023-01000-y
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- Article
Ultra rapid in vivo screening for anti-Alzheimer anti-amyloid drugs.
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- Scientific Reports, 2016, p. 23349, doi. 10.1038/srep23349
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- Article
Stepwise Structural Simplification of the Dihydroxyanthraquinone Moiety of a Multitarget Rhein-Based Anti-Alzheimer Lead to Improve Drug Metabolism and Pharmacokinetic Properties.
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- Pharmaceutics, 2024, v. 16, n. 8, p. 982, doi. 10.3390/pharmaceutics16080982
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- Article
Unveiling a novel transient druggable pocket in BACE-1 through molecular simulations: Conformational analysis and binding mode of multisite inhibitors.
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- PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0177683
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- Article
Novel Huprine Derivatives with Inhibitory Activity toward β-Amyloid Aggregation and Formation as Disease-Modifying Anti-Alzheimer Drug Candidates.
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- ChemMedChem, 2010, v. 5, n. 11, p. 1855, doi. 10.1002/cmdc.201000322
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- Article
Protective Role of a Donepezil-Huprine Hybrid against the β-Amyloid (1-42) Effect on Human Erythrocytes.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 17, p. 9563, doi. 10.3390/ijms22179563
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- Article
Neuroprotective Effects of the Multitarget Agent AVCRI104P3 in Brain of Middle-Aged Mice.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 9, p. 2615, doi. 10.3390/ijms19092615
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- Article
Spirostanol Sapogenins and Saponins from Convallaria majalis L. Structural Characterization by 2D NMR, Theoretical GIAO DFT Calculations and Molecular Modeling.
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- Molecules, 2021, v. 26, n. 10, p. 2999, doi. 10.3390/molecules26102999
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- Article
Ergosta-7,9(11),22-trien-3β-ol Alleviates Intracerebral Hemorrhage-Induced Brain Injury and BV-2 Microglial Activation.
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- Molecules, 2021, v. 26, n. 10, p. 2970, doi. 10.3390/molecules26102970
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- Article
AdipoRon, an Orally Active, Synthetic Agonist of AdipoR1 and AdipoR2 Receptors Has Gastroprotective Effect in Experimentally Induced Gastric Ulcers in Mice.
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- Molecules, 2021, v. 26, n. 10, p. 2946, doi. 10.3390/molecules26102946
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- Article
Antibody–Drug Conjugates—A Tutorial Review.
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- Molecules, 2021, v. 26, n. 10, p. 2943, doi. 10.3390/molecules26102943
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- Article
Discovery of a Novel Acetylcholinesterase Inhibitor by Fragment-Based Design and Virtual Screening.
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- Molecules, 2021, v. 26, n. 7, p. 2058, doi. 10.3390/molecules26072058
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- Article
Highlights on Steroidal Arylidene Derivatives as a Source of Pharmacologically Active Compounds: A Review.
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- Molecules, 2021, v. 26, n. 7, p. 2032, doi. 10.3390/molecules26072032
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- Article
Molecular Basis of the Therapeutical Potential of Clove (Syzygium aromaticum L.) and Clues to Its Anti-COVID-19 Utility.
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- Molecules, 2021, v. 26, n. 7, p. 1880, doi. 10.3390/molecules26071880
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- Article
In Vitro Study of the Fibrinolytic Activity via Single Chain Urokinase-Type Plasminogen Activator and Molecular Docking of FGFC1.
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- Molecules, 2021, v. 26, n. 7, p. 1816, doi. 10.3390/molecules26071816
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- Article
Insight into the Reaction of Alexidine with Sodium Hypochlorite: A Potential Error in Endodontic Treatment.
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- Molecules, 2021, v. 26, n. 6, p. 1623, doi. 10.3390/molecules26061623
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- Article
Engineering of Challenging G Protein-Coupled Receptors for Structure Determination and Biophysical Studies.
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- Molecules, 2021, v. 26, n. 5, p. 1465, doi. 10.3390/molecules26051465
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- Article
Expression of Luteinizing Hormone-Releasing Hormone (LHRH) and Type-I LHRH Receptor in Transitional Cell Carcinoma Type of Human Bladder Cancer.
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- Molecules, 2021, v. 26, n. 5, p. 1253, doi. 10.3390/molecules26051253
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- Article
Challenges and Perspectives of Standard Therapy and Drug Development in High-Grade Gliomas.
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- Molecules, 2021, v. 26, n. 4, p. 1169, doi. 10.3390/molecules26041169
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- Article
Synthesis, Characterization and In Vitro Evaluation of Novel 5-Ene-thiazolo[3,2- b ][1,2,4]triazole-6(5 H)-ones as Possible Anticancer Agents.
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- Molecules, 2021, v. 26, n. 4, p. 1162, doi. 10.3390/molecules26041162
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- Article
Synthesis, Neuroprotection, and Antioxidant Activity of 1,1′-Biphenylnitrones as α-Phenyl- N-tert -butylnitrone Analogues in In Vitro Ischemia Models.
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- Molecules, 2021, v. 26, n. 4, p. 1127, doi. 10.3390/molecules26041127
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- Article
Circulating Levels of Dephosphorylated-Uncarboxylated Matrix Gla Protein in Patients with Acute Coronary Syndrome.
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- Molecules, 2021, v. 26, n. 4, p. 1108, doi. 10.3390/molecules26041108
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- Article
The Cream of the Crop of the Medicinal Chemistry Section of Molecules —2019.
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- 2021
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- Editorial
Electron Paramagnetic Resonance Gives Evidence for the Presence of Type 1 Gonadotropin-Releasing Hormone Receptor (GnRH-R) in Subdomains of Lipid Rafts.
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- Molecules, 2021, v. 26, n. 4, p. 973, doi. 10.3390/molecules26040973
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- Article
Drug Discovery of Nucleos(t)ide Antiviral Agents: Dedicated to Prof. Dr. Erik De Clercq on Occasion of His 80th Birthday.
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- Molecules, 2021, v. 26, n. 4, p. 923, doi. 10.3390/molecules26040923
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- Article
Structural Insights into Ligand—Receptor Interactions Involved in Biased Agonism of G-Protein Coupled Receptors.
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- Molecules, 2021, v. 26, n. 4, p. 851, doi. 10.3390/molecules26040851
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- Article
Impact of the Metal Center and Leaving Group on the Anticancer Activity of Organometallic Complexes of Pyridine-2-carbothioamide †.
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- Molecules, 2021, v. 26, n. 4, p. 833, doi. 10.3390/molecules26040833
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- Article
Tentative Peptide‒Lipid Bilayer Models Elucidating Molecular Behaviors and Interactions Driving Passive Cellular Uptake of Collagen-Derived Small Peptides.
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- Molecules, 2021, v. 26, n. 3, p. 710, doi. 10.3390/molecules26030710
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- Article
PROTACs and Building Blocks: The 2D Chemical Space in Very Early Drug Discovery.
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- Molecules, 2021, v. 26, n. 3, p. 672, doi. 10.3390/molecules26030672
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- Article
Current Updates on Naturally Occurring Compounds Recognizing SARS-CoV-2 Druggable Targets.
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- Molecules, 2021, v. 26, n. 3, p. 632, doi. 10.3390/molecules26030632
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- Article
The Pharmaceutical Industry in 2020. An Analysis of FDA Drug Approvals from the Perspective of Molecules.
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- Molecules, 2021, v. 26, n. 3, p. 627, doi. 10.3390/molecules26030627
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- Article
Structure Activity Relationship of Key Heterocyclic Anti-Angiogenic Leads of Promising Potential in the Fight against Cancer.
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- Molecules, 2021, v. 26, n. 3, p. 553, doi. 10.3390/molecules26030553
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- Article
DNA-Binding Anticancer Drugs: One Target, Two Actions.
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- Molecules, 2021, v. 26, n. 3, p. 552, doi. 10.3390/molecules26030552
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- Article
Microwave-Assisted Synthesis, Structural Characterization and Assessment of the Antibacterial Activity of Some New Aminopyridine, Pyrrolidine, Piperidine and Morpholine Acetamides.
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- Molecules, 2021, v. 26, n. 3, p. 533, doi. 10.3390/molecules26030533
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- Article
Unravelling the Allosteric Targeting of PHGDH at the ACT-Binding Domain with a Photoactivatable Diazirine Probe and Mass Spectrometry Experiments †.
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- Molecules, 2021, v. 26, n. 2, p. 477, doi. 10.3390/molecules26020477
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- Article
Identification of the New In Vivo Metabolites of Ilaprazole in Rat Plasma after Oral Administration by LC-MS: In Silico Prediction of the H + /K + -ATPase Inhibitor.
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- Molecules, 2021, v. 26, n. 2, p. 459, doi. 10.3390/molecules26020459
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- Article
First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer's Disease.
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- Molecules, 2021, v. 26, n. 1, p. 80, doi. 10.3390/molecules26010080
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- Article
Docking Prediction, Antifungal Activity, Anti-Biofilm Effects on Candida spp., and Toxicity against Human Cells of Cinnamaldehyde.
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- Molecules, 2020, v. 25, n. 24, p. 5969, doi. 10.3390/molecules25245969
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- Article
An Alternative HIV-1 Non-Nucleoside Reverse Transcriptase Inhibition Mechanism: Targeting the p51 Subunit.
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- Molecules, 2020, v. 25, n. 24, p. 5902, doi. 10.3390/molecules25245902
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- Article
Comprehensive Review on Alzheimer's Disease: Causes and Treatment.
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- Molecules, 2020, v. 25, n. 24, p. 5789, doi. 10.3390/molecules25245789
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- Article
Permeation of β-Lactamase Inhibitors through the General Porins of Gram-Negative Bacteria.
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- Molecules, 2020, v. 25, n. 23, p. 5747, doi. 10.3390/molecules25235747
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- Article
Impact of C-Terminal Chemistry on Self-Assembled Morphology of Guanosine Containing Nucleopeptides.
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- Molecules, 2020, v. 25, n. 23, p. 5493, doi. 10.3390/molecules25235493
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- Article
Synthesis, Kinetic and Conformational Studies of 2-Substituted-5-(β-d-glucopyranosyl)-pyrimidin-4-ones as Potential Inhibitors of Glycogen Phosphorylase.
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- Molecules, 2020, v. 25, n. 22, p. 5463, doi. 10.3390/molecules25225463
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- Article
A Comprehensive Review of Aminochalcones.
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- Molecules, 2020, v. 25, n. 22, p. 5381, doi. 10.3390/molecules25225381
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- Article
Pharmacological Characterization of 4-Methylthioamphetamine Derivatives.
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- Molecules, 2020, v. 25, n. 22, p. 5310, doi. 10.3390/molecules25225310
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- Article
Photoactivatable Platinum-Based Anticancer Drugs: Mode of Photoactivation and Mechanism of Action.
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- Molecules, 2020, v. 25, n. 21, p. 5167, doi. 10.3390/molecules25215167
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- Article