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Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model.
Published in:
Nature Medicine, 2006, v. 12, n. 7, p. 801, doi. 10.1038/nm1423
By:
- McLaurin, JoAnne;
- Kierstead, Meredith E;
- Brown, Mary E;
- Hawkes, Cheryl A;
- Lambermon, Mark H L;
- Phinney, Amie L;
- Darabie, Audrey A;
- Cousins, Julian E;
- French, Janet E;
- Lan, Melissa F;
- Fusheng Chen;
- Wong, Sydney S N;
- Mount, Howard T J;
- Fraser, Paul E;
- Westaway, David;
- George-Hyslop, Peter St
Publication type:
Article
Analysis of Aβ and neuroinflammation as a function of brain region and disease progression in the TgCRND8 brain
Published in:
2009
By:
- Ma, Keran;
- Mount, Howard T.J.;
- McLaurin, JoAnne
Publication type:
Abstract
P4-149: Shadoo is a novel mammalian protein exhibiting partial redundancy with PRPC
Published in:
2006
By:
- Watts, Joel C.;
- Drisaldi, Bettina;
- Strome, Bob;
- Yang, Jing;
- Fraser, Paul E.;
- Mount, Howard T.J.;
- Schmitt-Ulms, Gerold;
- Westaway, David
Publication type:
Abstract
P1-041: Disruption of object recognition memory in hamster PRP promoter-driven transgenic mouse models of neurodegenerative disease
Published in:
2006
By:
- Mount, Howard T.J.;
- Francis, Beverly M.;
- Kim, John H.;
- Kierstead, Meredith E.;
- Tandon, Anurag;
- McLaurin, JoAnne
Publication type:
Abstract
P1-032: Decreased BDNF mRNA levels in mouse models of Alzheimer’s disease
Published in:
2006
By:
- Fahnestock, Margaret;
- Garzon, Diego;
- Peng, Shiyong;
- Flood, Dorothy;
- Salehi, Ahmad;
- Mount, Howard T.J.
Publication type:
Abstract
P4-149: Shadoo is a novel mammalian protein exhibiting partial redundancy with PRPC
Published in:
2006
By:
- Watts, Joel C.;
- Drisaldi, Bettina;
- Strome, Bob;
- Yang, Jing;
- Fraser, Paul E.;
- Mount, Howard T.J.;
- Schmitt-Ulms, Gerold;
- Westaway, David
Publication type:
Abstract
P1-041: Disruption of object recognition memory in hamster PRP promoter-driven transgenic mouse models of neurodegenerative disease
Published in:
2006
By:
- Mount, Howard T.J.;
- Francis, Beverly M.;
- Kim, John H.;
- Kierstead, Meredith E.;
- Tandon, Anurag;
- McLaurin, JoAnne
Publication type:
Abstract
P1-032: Decreased BDNF mRNA levels in mouse models of Alzheimer’s disease
Published in:
2006
By:
- Fahnestock, Margaret;
- Garzon, Diego;
- Peng, Shiyong;
- Flood, Dorothy;
- Salehi, Ahmad;
- Mount, Howard T.J.
Publication type:
Abstract
Interactions between β-amyloid and central cholinergic neurons: implications for Alzheimer's disease.
Published in:
Journal of Psychiatry & Neuroscience, 2004, v. 29, n. 6, p. 427
By:
- Kar, Satyabrata;
- Slowikowski, Stephen P. M.;
- Westaway, David;
- Mount, Howard T. J.
Publication type:
Article
In utero exposure to protease inhibitor-based antiretroviral regimens delays growth and developmental milestones in mice.
Published in:
PLoS ONE, 2020, v. 15, n. 11, p. 1, doi. 10.1371/journal.pone.0242513
By:
- Sarkar, Ambalika;
- Balogun, Kayode;
- Guzman Lenis, Monica S.;
- Acosta, Sebastian;
- Mount, Howard T.;
- Serghides, Lena
Publication type:
Article
Subtypes of excitatory amino acid receptors involved in the stimulation of [3H]dopamine release from cell cultures of rat ventral mesencephalon.
Published in:
Synapse, 1990, v. 5, n. 4, p. 271, doi. 10.1002/syn.890050404
By:
- Mount, Howard;
- Quirion, Rémi;
- Kohn-Alexander, Judity;
- Boksa, Patricia
Publication type:
Article
Age-Dependent Impairment of Spine Morphology and Synaptic Plasticity in Hippocampal CA1 Neurons of a Presenilin 1 Transgenic Mouse Model of Alzheimer's Disease.
Published in:
Journal of Neuroscience, 2009, v. 29, n. 32, p. 10144, doi. 10.1523/JNEUROSCI.1856-09.2009
By:
- Auffret, Alexandra;
- Gautheron, Vanessa;
- Repici, Mariaelena;
- Kraftsik, Rudolf;
- Mount, Howard T. J.;
- Mariani, Jean;
- Rovira, Catherine
Publication type:
Article
Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease.
Published in:
Journal of Neuroscience, 2009, v. 29, n. 29, p. 9321, doi. 10.1523/JNEUROSCI.4736-08.2009
By:
- Shiyong Peng;
- Garzon, Diego J.;
- Marchese, Monica;
- Klein, William;
- Ginsberg, Stephen D.;
- Francis, Beverly M.;
- Mount, Howard T. J.;
- Mufson, Elliott J.;
- Salehi, Ahmad;
- Fahnestock, Margaret
Publication type:
Article
α5GABAA Receptors Mediate the Amnestic But Not Sedative- Hypnotic Effects of the General Anesthetic Etomidate.
Published in:
Journal of Neuroscience, 2006, v. 26, n. 14, p. 3713, doi. 10.1523/JNEUROSCI.5024-05.2006
By:
- Cheng, Victor Y.;
- Martin, Loren J.;
- Elliott, Erin M.;
- Kim, John H.;
- Mount, Howard T. J.;
- Taverna, Franco A.;
- Roder, John C.;
- MacDonald, John F.;
- Bhambri, Amit;
- Collinson, Neil;
- Wafford, Keith A.;
- Orser, Beverley A.
Publication type:
Article
The CNS glycoprotein Shadoo has PrPC-like protective properties and displays reduced levels in prion infections.
Published in:
EMBO Journal, 2007, v. 26, n. 17, p. 4038, doi. 10.1038/sj.emboj.7601830
By:
- Watts, Joel C;
- Drisaldi, Bettina;
- Ng, Vivian;
- Yang, Jing;
- Strome, Bob;
- Horne, Patrick;
- Sy, Man-Sun;
- Yoong, Larry;
- Young, Rebecca;
- Mastrangelo, Peter;
- Bergeron, Catherine;
- Fraser, Paul E.;
- Carlson, George A.;
- Mount, Howard T. J.;
- Schmitt-Ulms, Gerold;
- Westaway, David
Publication type:
Article
Reduced Tissue Levels of Noradrenaline Are Associated with Behavioral Phenotypes of the TgCRND8 Mouse Model of Alzheimer's Disease.
Published in:
Neuropsychopharmacology, 2012, v. 37, n. 8, p. 1934, doi. 10.1038/npp.2012.40
By:
- Francis, Beverly M;
- Yang, Jimao;
- Hajderi, Enid;
- Brown, Mary E;
- Michalski, Bernadeta;
- McLaurin, JoAnne;
- Fahnestock, Margaret;
- Mount, Howard T J
Publication type:
Article
Brainstem Concentrations of Cholesterol are not Influenced by Genetic Ablation of the Low-Density Lipoprotein Receptor.
Published in:
Neurochemical Research, 2009, v. 34, n. 2, p. 311, doi. 10.1007/s11064-008-9777-7
By:
- Ameer Taha;
- Chuck Chen;
- Zhen Liu;
- John Kim;
- Howard Mount;
- Richard Bazinet
Publication type:
Article
Unesterified docosahexaenoic acid is protective in neuroinflammation.
Published in:
Journal of Neurochemistry, 2013, v. 127, n. 3, p. 378, doi. 10.1111/jnc.12392
By:
- Orr, Sarah K.;
- Palumbo, Sara;
- Bosetti, Francesca;
- Mount, Howard T.;
- Kang, Jing X.;
- Greenwood, Carol E.;
- Ma, David W. L.;
- Serhan, Charles N.;
- Bazinet, Richard P.
Publication type:
Article
Experimental Malaria in Pregnancy Induces Neurocognitive Injury in Uninfected Offspring via a C5a-C5a Receptor Dependent Pathway.
Published in:
PLoS Pathogens, 2015, v. 11, n. 9, p. 1, doi. 10.1371/journal.ppat.1005140
By:
- McDonald, Chloë R.;
- Cahill, Lindsay S.;
- Ho, Keith T.;
- Yang, Jimmy;
- Kim, Hani;
- Silver, Karlee L.;
- Ward, Peter A.;
- Mount, Howard T.;
- Liles, W. Conrad;
- Sled, John G.;
- Kain, Kevin C.
Publication type:
Article
PPARγ Agonists Improve Survival and Neurocognitive Outcomes in Experimental Cerebral Malaria and Induce Neuroprotective Pathways in Human Malaria.
Published in:
PLoS Pathogens, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.ppat.1003980
By:
- Serghides, Lena;
- McDonald, Chloe R.;
- Lu, Ziyue;
- Friedel, Miriam;
- Cui, Cheryl;
- Ho, Keith T.;
- Mount, Howard T. J.;
- Sled, John G.;
- Kain, Kevin C.
Publication type:
Article
Amyloid Beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease.
Published in:
Nature, 2000, v. 408, n. 6815, p. 979, doi. 10.1038/35050110
By:
- Janus, Christopher;
- Pearson, Jacqueline;
- McLaurin, JoAnne;
- Mathews, Paul M.;
- Jiang, Ying;
- Schmidt, Stephen D.;
- Chishti, M. Azhar;
- Horne, Patrick;
- Heslin, Donna;
- French, Janet;
- Mount, Howard T.J.;
- Nixon, Ralph A.;
- Mercken, Marc;
- Bergeron, Catherine;
- Fraser, Paul E.;
- St. George-Hyslop, Peter;
- Westaway, David
Publication type:
Article
Viral alpha-synuclein knockdown prevents spreading synucleinopathy.
Published in:
Brain Communications, 2021, v. 3, n. 4, p. 1, doi. 10.1093/braincomms/fcab247
By:
- Menon, Sindhu;
- Kofoed, Rikke H.;
- Nabbouh, Fadl;
- Xhima, Kristiana;
- Al-Fahoum, Yasmeen;
- Langman, Tammy;
- Mount, Howard T. J.;
- Shihabuddin, Lamya S.;
- Sardi, S. Pablo;
- Fraser, Paul E.;
- Watts, Joel C.;
- Aubert, Isabelle;
- Tandon, Anurag
Publication type:
Article
Perinatal exposure to atazanavir-based antiretroviral regimens in a mouse model leads to differential long-term motor and cognitive deficits dependent on the NRTI backbone.
Published in:
Frontiers in Molecular Neuroscience, 2024, p. 1, doi. 10.3389/fnmol.2024.1376681
By:
- Dhume, Shreya H.;
- Balogun, Kayode;
- Sarkar, Ambalika;
- Acosta, Sebastian;
- Mount, Howard T. J.;
- Cahill, Lindsay S.;
- Sled, John G.;
- Serghides, Lena
Publication type:
Article
Muscarinic Stimulation Promotes Cultured Purkinje Cell Survival: A Role for Acetylcholine in Cerebellar Development?
Published in:
Journal of Neurochemistry, 1994, v. 63, n. 6, p. 2065, doi. 10.1046/j.1471-4159.1994.63062065.x
By:
- Mount, Howard T. J.;
- Dreyfus, Cheryl F.;
- Black, Ira B.
Publication type:
Article
Stimulation of Dopamine Release from Cultured Rat Mesencephalic Cells by Naturally Occurring Excitatory Amino Acids: Involvement of Both N-Methyl-D-Aspartate (NMDA) and Non-NMDA Receptor Subtypes.
Published in:
Journal of Neurochemistry, 1990, v. 55, n. 1, p. 268, doi. 10.1111/j.1471-4159.1990.tb08848.x
By:
- Mount, Howard;
- Quirion, Rémi;
- Chaudieu, Isabelle;
- Boksa, Patricia
Publication type:
Article
Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia-telangiectasia.
Published in:
Journal of Neurochemistry, 2004, v. 88, n. 6, p. 1449, doi. 10.1046/j.1471-4159.2003.02278.x
By:
- Mount, Howard T. J.;
- Martel, Jean-Claude;
- Fluit, Paul;
- Yingji Wu, Paul;
- Gallo-Hendrikx, Eleanor;
- Cosi, Cristina;
- Marien, Marc R.
Publication type:
Article
Differential Involvement of Metabotropic and p75 Neurotrophin Receptors in Effects of Nerve Growth Factor and Neurotrophin-3 on Cultured Purkinje Cell Survival.
Published in:
Journal of Neurochemistry, 1998, v. 70, n. 3, p. 1045, doi. 10.1046/j.1471-4159.1998.70031045.x
By:
- Mount, Howard T. J.;
- Elkabes, Stella;
- Dreyfus, Cheryl F.;
- Black, Ira B.
Publication type:
Article

Found: 27

Cyclohexanehexol inhibitors of Aβ aggregation prevent and reverse Alzheimer phenotype in a mouse model.

Analysis of Aβ and neuroinflammation as a function of brain region and disease progression in the TgCRND8 brain

P4-149: Shadoo is a novel mammalian protein exhibiting partial redundancy with PRPC

P1-041: Disruption of object recognition memory in hamster PRP promoter-driven transgenic mouse models of neurodegenerative disease

P1-032: Decreased BDNF mRNA levels in mouse models of Alzheimer’s disease

P4-149: Shadoo is a novel mammalian protein exhibiting partial redundancy with PRPC

P1-041: Disruption of object recognition memory in hamster PRP promoter-driven transgenic mouse models of neurodegenerative disease

P1-032: Decreased BDNF mRNA levels in mouse models of Alzheimer’s disease

Interactions between β-amyloid and central cholinergic neurons: implications for Alzheimer's disease.

In utero exposure to protease inhibitor-based antiretroviral regimens delays growth and developmental milestones in mice.

Subtypes of excitatory amino acid receptors involved in the stimulation of [<sup>3</sup>H]dopamine release from cell cultures of rat ventral mesencephalon.

Age-Dependent Impairment of Spine Morphology and Synaptic Plasticity in Hippocampal CA1 Neurons of a Presenilin 1 Transgenic Mouse Model of Alzheimer's Disease.

Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease.

α5GABA<sub>A</sub> Receptors Mediate the Amnestic But Not Sedative- Hypnotic Effects of the General Anesthetic Etomidate.

The CNS glycoprotein Shadoo has PrP<sup>C</sup>-like protective properties and displays reduced levels in prion infections.

Reduced Tissue Levels of Noradrenaline Are Associated with Behavioral Phenotypes of the TgCRND8 Mouse Model of Alzheimer's Disease.

Brainstem Concentrations of Cholesterol are not Influenced by Genetic Ablation of the Low-Density Lipoprotein Receptor.

Unesterified docosahexaenoic acid is protective in neuroinflammation.

Experimental Malaria in Pregnancy Induces Neurocognitive Injury in Uninfected Offspring via a C5a-C5a Receptor Dependent Pathway.

PPARγ Agonists Improve Survival and Neurocognitive Outcomes in Experimental Cerebral Malaria and Induce Neuroprotective Pathways in Human Malaria.

Amyloid Beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease.

Viral alpha-synuclein knockdown prevents spreading synucleinopathy.

Perinatal exposure to atazanavir-based antiretroviral regimens in a mouse model leads to differential long-term motor and cognitive deficits dependent on the NRTI backbone.

Muscarinic Stimulation Promotes Cultured Purkinje Cell Survival: A Role for Acetylcholine in Cerebellar Development?

Stimulation of Dopamine Release from Cultured Rat Mesencephalic Cells by Naturally Occurring Excitatory Amino Acids: Involvement of Both N-Methyl-D-Aspartate (NMDA) and Non-NMDA Receptor Subtypes.

Progressive sensorimotor impairment is not associated with reduced dopamine and high energy phosphate donors in a model of ataxia-telangiectasia.

Differential Involvement of Metabotropic and p75 Neurotrophin Receptors in Effects of Nerve Growth Factor and Neurotrophin-3 on Cultured Purkinje Cell Survival.