Works matching AU Mossman, Brooke T.

Results: 58

ROLE OF MITOGEN-ACTIVATED PROTEIN KINASES, EARLY RESPONSE PROTOONCOGENES, AND ACTIVATOR PROTEIN-1 IN CELL SIGNALING BY ASBESTOS.

Published in:

Inhalation Toxicology, 2000, v. 12, p. 307, doi. 10.1080/08958378.2000.11463240

By:

Mossman, Brooke T.;
Hubbard, Andrea;
Shukla, Arti;
Timblin, Cynthia R.

Publication type:

Article

MECHANISMS OF ACTION OF POORLY SOLUBLE PARTICULATES IN OVERLOAD-RELATED LUNG PATHOLOGY.

Published in:

Inhalation Toxicology, 2000, v. 12, n. 1/2, p. 141, doi. 10.1080/089583700196572

By:

Mossman, Brooke T.

Publication type:

Article

Extracellular Signal-Regulated Kinase 5 and Cyclic AMP Response Element Binding Protein Are Novel Pathways Inhibited by Vandetanib (ZD6474) and Doxorubicin in Mesotheliomas.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2014, v. 51, n. 5, p. 595, doi. 10.1165/rcmb.2013-0373TR

By:

Sayan, Mutlay;
Shukla, Arti;
MacPherson, Maximilian B.;
Macura, Sherrill L.;
Hillegass, Jedd M.;
Perkins, Timothy N.;
Thompson, Joyce K.;
Beuschel, Stacie L.;
Miller, Jill M.;
Mossman, Brooke T.

Publication type:

Article

An Extracellular Signal-Regulated Kinase 2 Survival Pathway Mediates Resistance of Human Mesothelioma Cells to Asbestos-Induced Injury.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2011, v. 45, n. 5, p. 906, doi. 10.1165/rcmb.2010-0282OC

By:

Shukla, Arti;
Barrett, Trisha F.;
MacPherson, Maximilian B.;
Hillegass, Jedd M.;
Fukagawa, Naomi K.;
Swain, William A.;
O'Byrne, Kenneth J.;
Testa, Joseph R.;
Pass, Harvey I.;
Faux, Stephen P.;
Mossman, Brooke T.

Publication type:

Article

Asbestos, Lung Cancers, and Mesotheliomas.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2010, v. 42, n. 2, p. 133, doi. 10.1165/rcmb.2009-0206TR

By:

Heintz, Nicholas H.;
Janssen-Heininger, Yvonne M. W.;
Mossman, Brooke T.

Publication type:

Article

Alterations in Gene Expression in Human Mesothelial Cells Correlate with Mineral Pathogenicity.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2009, v. 41, n. 1, p. 114, doi. 10.1165/rcmb.2008-0146OC

By:

Shukla, Arti;
MacPherson, Maximilian B.;
Hillegass, Jedd;
Ramos-Nino, Maria E.;
Alexeeva, Vlada;
Vacek, Pamela M.;
Bond, Jeffrey P.;
Pass, Harvey I.;
Steele, Chad;
Mossman, Brooke T.

Publication type:

Article

Targeting the MEK1 Cascade in Lung Epithelium Inhibits Proliferation and Fibrogenesis by Asbestos.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2008, v. 38, n. 5, p. 618, doi. 10.1165/rcmb.2007-0382OC

By:

Manning, Christopher B.;
Sabo-Attwood, Tara;
Robledo, Raymond F.;
MacPherson, Maximilian B.;
Rincón, Mercedes;
Vacek, Pamela;
Hemenway, David;
Taatjes, Douglas J.;
Lee, Patty J.;
Mossman, Brooke T.

Publication type:

Article

HGF Mediates Cell Proliferation of Human Mesothelioma Cells through a PI3K/MEK5/Fra-1 Pathway.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2008, v. 38, n. 2, p. 209, doi. 10.1165/rcmb.2007-0206OC

By:

Ramos-Nino, Maria E.;
Blumen, Steven R.;
Sabo-Attwood, Tara;
Pass, Harvey;
Carbone, Michele;
Testa, Joseph R.;
Altomare, Deborah A.;
Mossman, Brooke T.

Publication type:

Article

Decreased Asbestos-Induced Lung Inflammation and Fibrosis after Radiation and Bone Marrow Transplant.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2008, v. 38, n. 1, p. 16, doi. 10.1165/rcmb.2007-0249OC

By:

Levis, Jamie;
Loi, Roberto;
Butnor, Kelly J.;
Vacek, Pamela;
Steele, Chad;
Mossman, Brooke T.;
Weiss, Daniel J.

Publication type:

Article

Unique Uptake of Acid-Prepared Mesoporous Spheres by Lung Epithelial and Mesothelioma Cells.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2007, v. 36, n. 3, p. 333, doi. 10.1165/rcmb.2006-0319OC

By:

Blumen, Steven R.;
Kai Cheng;
Ramos-Nino, Maria E.;
Taatjes, Douglas J.;
Weiss, Daniel J.;
Landry, Christopher C.;
Mossman, Brooke T.

Publication type:

Article

Oxidants and Signaling by Mitogen-Activated Protein Kinases in Lung Epithelium.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2006, v. 34, n. 6, p. 666, doi. 10.1165/rcmb.2006-0047SF

By:

Mossman, Brooke T.;
Lounsbury, Karen M.;
Reddy, Sekhar P.

Publication type:

Article

Airway Epithelium, Inflammation, and Mechanisms of Disease: A Tribute to Carol B. Basbaum.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2006, v. 34, n. 5, p. 523, doi. 10.1165/rcmb.F311

By:

ADLER, KENNETH B.;
SHAPIRO, STEVEN D.;
GALLUP, MARIANNE;
REEN WU;
RANDELL, SCOTT H.;
HOLTZMAN, MICHAEL J.;
EVANS, CHRISTOPHER M.;
JACOBY, DAVID B.;
TESFAIGZI, YOHANNES;
ROSE, MARY C.;
MOSSMAN, BROOKE T.;
PRINCE, ALICE;
REDDY, SEKHAR P.;
DAVIS, C. WILLIAM;
MATTHAY, MICHAEL A.

Publication type:

Article

Oxidant-Mediated cAMP Response Element Binding Protein Activation.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2006, v. 34, n. 1, p. 7, doi. 10.1165/rcmb.2005-0153OC

By:

Barlow, Christy A.;
Shukla, Arti;
Mossman, Brooke T.;
Lounsbury, Karen M.

Publication type:

Article

Paclitaxel and vinorelbine cause synergistic increases in apoptosis but not in microtubular disruption in human lung adenocarcinoma cells (A-549).

Published in:

Histochemistry & Cell Biology, 2004, v. 121, n. 2, p. 115, doi. 10.1007/s00418-004-0618-8

By:

Jung, Michael;
Grunberg, Steven;
Timblin, Cynthia;
Buder-Hoffman, Sylke;
Vacek, Pamela;
Taatjes, Douglas J.;
Mossman, Brooke T.

Publication type:

Article

Letter to the Editor: Fletcher NM, Harper AK, Memaj I, Fan R, Morris RT, Saed GM. Molecular Basis Supporting the Association of Talcum Powder Use with Increased Risk of Ovarian Cancer. Reprod Sci. 2019;26(12):1603–12. DOI: 10.1177/1933719119831773.

Published in:

2020

By:

Mossman, Brooke T.

Publication type:

Letter

Asbestos-Induced Apoptosis Is Protein Kinase Cδ-Dependent.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2003, v. 29, n. 2, p. 198, doi. 10.1165/rcmb.2002-0248OC

By:

Shukla, Arti;
Stern, Maria;
Lounsbury, Karen M.;
Flanders, Trisha;
Mossman, Brooke T.

Publication type:

Article

SV40, Growth Factors, and Mesothelioma.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2002, v. 26, n. 2, p. 167, doi. 10.1165/ajrcmb.26.2.f229

By:

Mossman, Brooke T.;
Gruenert, Dieter C.

Publication type:

Article

Inhaled Particulate Matter Causes Expression of Nuclear Factor (NF)-κB--Related Genes and Oxidant-Dependent NF-κB Activation In Vitro.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2000, v. 23, n. 2, p. 182, doi. 10.1165/ajrcmb.23.2.4035

By:

Shukla, Arti;
Timblin, Cynthia;
BeruBe, Kelly;
Gordon, Terry;
McKinney, Willie;
Driscoll, Kevin;
Vacek, Pamela;
Mossman, Brooke T.

Publication type:

Article

ERK1/2 mitogen-activated protein kinase selectively mediates IL-13-induced lung inflammation and remodeling in vivo.

Published in:

2006

By:

Lee, Patty J.;
Xuchen Zhang;
Peiying Shan;
Bing Ma;
Chun Geun Lee;
Homer, Robert J.;
Zhou Zhu;
Rincon, Mercedes;
Mossman, Brooke T.;
Elias, Jack A.;
Zhang, Xuchen;
Shan, Peiying;
Ma, Bing;
Lee, Chun Geun;
Zhu, Zhou

Publication type:

journal article

Assessing nanotoxicity in cells in vitro.

Published in:

WIREs: Nanomedicine & Nanobiotechnology, 2010, v. 2, n. 3, p. 219, doi. 10.1002/wnan.54

By:

Hillegass, Jedd M.;
Shukla, Arti;
Lathrop, Sherrill A.;
MacPherson, Maximilian B.;
Fukagawa, Naomi K.;
Mossman, Brooke T.

Publication type:

Article

Review Article.

Published in:

Toxicologic Pathology, 1999, v. 27, n. 2, p. 180, doi. 10.1177/019262339902700205

By:

Mossman, Brooke T.

Publication type:

Article

Development and Characterization of a Rapid-Onset Rodent Inhalation Model of Asbestosis for Disease Prevention*1.

Published in:

Toxicologic Pathology, 1991, v. 19, n. 4/1, p. 412, doi. 10.1177/019262339101900410

By:

Mossman, Brooke T.;
Janssen, Yvonne M.;
Marsh, Joanne P.;
Sesko, Ann;
Shatos, Marie A.;
Doherty, Jacqueline;
Adler, Kenneth B.;
Piemenway, David;
Mickey, Ruth;
Vacek, Pamela;
Petruska, Janet;
Kagan, Elliott

Publication type:

Article

CARCINOGENESIS AND RELATED CELL AND TISSUE RESPONSES TO ASBESTOS: A REVIEW.

Published in:

Annals of Occupational Hygiene, 1994, v. 38, n. 4, p. 617

By:

MOSSMAN, BROOKE T.

Publication type:

Article

Utilization of Gene Profiling and Proteomics to Determine Mineral Pathogenicity in a Human Mesothelial Cell Line (LP9/TERT-1).

Published in:

Journal of Toxicology & Environmental Health: Part A, 2010, v. 73, n. 5/6, p. 423, doi. 10.1080/15287390903486568

By:

Hillegass, Jedd M.;
Shukla, Arti;
MacPherson, Maximilian B.;
Bond, Jeffrey P.;
Steele, Chad;
Mossman, Brooke T.

Publication type:

Article

INFLAMMATORY RESPONSES TO INHALED AGENTS: Abstracts of the 2000 British Association for Lung Research.

Published in:

2001

By:

Bjorksten, Bengt;
Mossman, Brooke T.;
Timblin, Cynthia;
Shukla, Arti;
Hubbard, Andrea;
BeruBe, Kelly;
Driscoll, Kevin;
Churg, Andrew;
Mahon, Bernard P.;
Williams, T.J.;
Adcock, Ian M.;
Hiemstra, Pieter S.;
Adler, Kenneth B.;
Martin, Linda D.;
Yuehua Li;
Rossi, A.G.;
Martin, M.C.

Publication type:

Abstract

Glycoprotein Synthesis by an Established Cell Line from Hamster Tracheal Epithelium.

Published in:

Experimental Lung Research, 1980, v. 1, n. 2, p. 89, doi. 10.3109/01902148009069639

By:

Last, Jerold A.;
Kaizu, Tokio;
Mossman, Brooke T.

Publication type:

Article

The NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseases.

Published in:

Particle & Fibre Toxicology, 2016, p. 1, doi. 10.1186/s12989-016-0162-4

By:

Sayan, Mutlay;
Mossman, Brooke T.

Publication type:

Article

Blocking of ERK1 and ERK2 sensitizes human mesothelioma cells to doxorubicin.

Published in:

Molecular Cancer, 2010, v. 9, p. 314, doi. 10.1186/1476-4598-9-314

By:

Shukla, Arti;
Hillegass, Jedd M.;
MacPherson, Maximilian B.;
Beuschel, Stacie L.;
Vacek, Pamela M.;
Pass, Harvey I.;
.Carbone, Michele;
Testa, Joseph R.;
Mossman, Brooke T.

Publication type:

Article

Fra-1 governs cell migration via modulation of CD44 expression inhuman mesotheliomas.

Published in:

Molecular Cancer, 2007, v. 6, p. 81, doi. 10.1186/1476-4598-6-81

By:

Ramos-Nino, Maria E.;
Blumen, Steven R.;
Pass, Harvey;
Mossman, Brooke T.

Publication type:

Article

Cellular and molecular parameters of mesothelioma.

Published in:

Journal of Cellular Biochemistry, 2006, v. 98, n. 4, p. 723, doi. 10.1002/jcb.20828

By:

Maria E. Ramos‐Nino;
Joseph R. Testa;
Deborah A. Altomare;
Harvey I. Pass;
Michele Carbone;
Maurizio Bocchetta;
Brooke T. Mossman

Publication type:

Article

Gd-Labeled Microparticles in MRI: In vivo Imaging of Microparticles After Intraperitoneal Injection.

Published in:

Small, 2010, v. 6, n. 23, p. 2678, doi. 10.1002/smll.201001447

By:

Steinbacher, Jeremy L.;
Lathrop, Sherrill A.;
Cheng, Kai;
Hillegass, Jedd M.;
Butnor, Kelly J.;
Kauppinen, Risto A.;
Mossman, Brooke T.;
Landry, Christopher C.

Publication type:

Article

ERK2 is essential for the growth of human epithelioid malignant mesotheliomas.

Published in:

International Journal of Cancer, 2011, v. 129, n. 5, p. 1075, doi. 10.1002/ijc.25763

By:

Shukla, Arti;
Hillegass, Jedd M.;
MacPherson, Maximilian B.;
Beuschel, Stacie L.;
Vacek, Pamela M.;
Butnor, Kelly J.;
Pass, Harvey I.;
Carbone, Michele;
Testa, Joseph R.;
Heintz, Nicholas H.;
Mossman, Brooke T.

Publication type:

Article

Increased efficacy of doxorubicin delivered in multifunctional microparticles for mesothelioma therapy.

Published in:

International Journal of Cancer, 2011, v. 129, n. 1, p. 233, doi. 10.1002/ijc.25666

By:

Hillegass, Jedd M.;
Blumen, Steven R.;
Cheng, Kai;
MacPherson, Maximilian B.;
Alexeeva, Vlada;
Lathrop, Sherrill A.;
Beuschel, Stacie L.;
Steinbacher, Jeremy L.;
Butnor, Kelly J.;
Ramos-Niño, Maria E.;
Shukla, Arti;
James, Ted A.;
Weiss, Daniel J.;
Taatjes, Douglas J.;
Pass, Harvey I.;
Carbone, Michele;
Landry, Christopher C.;
Mossman, Brooke T.

Publication type:

Article

Asbestos modulates thioredoxin-thioredoxin interacting protein interaction to regulate inflammasome activation.

Published in:

Particle & Fibre Toxicology, 2014, v. 11, n. 1, p. 2, doi. 10.1186/1743-8977-11-24

By:

Thompson, Joyce K.;
Westbom, Catherine M.;
MacPherson, Maximilian B.;
Mossman, Brooke T.;
Heintz, Nicholas H.;
Spiess, Page;
Shukla, Arti

Publication type:

Article

Asbestos and erionite prime and activate the NLRP3 inflammasome that stimulates autocrine cytokine release in human mesothelial cells.

Published in:

Particle & Fibre Toxicology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1743-8977-10-39

By:

Hillegass, Jedd M;
Miller, Jill M;
MacPherson, Maximilian B;
Westbom, Catherine M;
Sayan, Mutlay;
Thompson, Joyce K;
Macura, Sherrill L;
Perkins, Timothy N;
Beuschel, Stacie L;
Alexeeva, Vlada;
Pass, Harvey I;
Steele, Chad;
Mossman, Brooke T;
Shukla, Arti

Publication type:

Article

Silica induces NLRP3 inflammasome activation in human lung epithelial cells.

Published in:

Particle & Fibre Toxicology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1743-8977-10-3

By:

Peeters, Paul M.;
Perkins, Timothy N.;
Wouters, Emiel F. M.;
Mossman, Brooke T.;
Reynaer, Niki L.

Publication type:

Article

Mechanisms of oxidative stress and alterations ingene expression by Libby six-mix in humanmesothelial cells.

Published in:

Particle & Fibre Toxicology, 2010, v. 7, p. 26, doi. 10.1186/1743-8977-7-26

By:

Hillegass, Jedd M.;
Shukla, Arti;
MacPherson, Maximilian B.;
Lathrop, Sherrill A.;
Alexeeva, Vlada;
Perkins, Timothy N.;
van der Vliet, Albert;
Vacek, Pamela M.;
Gunter, Mickey E.;
Mossman, Brooke T.

Publication type:

Article

Mechanisms of action of inhaled fibers, particles and nanoparticles in lung and cardiovascular diseases.

Published in:

Particle & Fibre Toxicology, 2007, v. 4, p. 4, doi. 10.1186/1743-8977-4-4

By:

Mossman, Brooke T.;
Borm, Paul J.;
Castranova, Vincent;
Costa, Daniel L.;
Donaldson, Kenneth;
Kleeberger, Steven R.

Publication type:

Article

Bioreactivity of the crystalline silica polymorphs, quartz and cristobalite, and implications for occupational exposure limits (OELs).

Published in:

Critical Reviews in Toxicology, 2013, v. 43, n. 8, p. 632, doi. 10.3109/10408444.2013.818617

By:

Mossman, Brooke T.;
Glenn, Robert E.

Publication type:

Article

Inflammation precedes the development of human malignant mesotheliomas in a SCID mouse xenograft model.

Published in:

Annals of the New York Academy of Sciences, 2010, v. 1203, n. 1, p. 7, doi. 10.1111/j.1749-6632.2010.05554.x

By:

Hillegass, Jedd M.;
Shukla, Arti;
Lathrop, Sherrill A.;
MacPherson, Maximilian B.;
Beuschel, Stacie L.;
Butnor, Kelly J.;
Testa, Joseph R.;
Pass, Harvey I.;
Carbone, Michele;
Steele, Chad;
Mossman, Brooke T.

Publication type:

Article

Expression of GPC3, an X-linked recessive overgrowth gene, is silenced in malignant mesothelioma.

Published in:

Oncogene, 2000, v. 19, n. 3, p. 410, doi. 10.1038/sj.onc.1203322

By:

Murthy, Siva S;
Shen, Tong;
De Rienzo, Assunta;
Lee, Wen-Ching;
Ferriola, Patrice C;
Jhanwar, Suresh C;
Mossman, Brooke T;
Filmus, Jorge;
Testa, Joseph R

Publication type:

Article

Cyclic AMP response element binding protein (CREB) regulation by asbestos.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A180, doi. 10.1096/fasebj.21.5.a180-c

By:

Shukla, Arti;
Barrett, Trisha F.;
Barlow, Christy A.;
Lounsbury, Karen M.;
Mossman, Brooke T.

Publication type:

Article

Transcriptional up-regulation of MMPs 12 and 13 by asbestos occurs via a PKCδ-dependent pathway in murine lung.

Published in:

FASEB Journal, 2006, v. 20, n. 7, p. 997, doi. 10.1096/fj.05-4554fje

By:

Shukla, Arti;
Barrett, Trisha F.;
Nakayama, Keiichi I.;
Nakayama, Keiko;
Mossman, Brooke T.;
Lounsbury, Karen M.

Publication type:

Article

Microspheres targeted with a mesothelin antibody and loaded with doxorubicin reduce tumor volume of human mesotheliomas in xenografts.

Published in:

2013

By:

Macura, Sherrill L.;
Steinbacher, Jeremy L.;
MacPherson, Maximilian B.;
Lathrop, Melissa J.;
Sayan, Mutlay;
Hillegass, Jedd M.;
Beuschel, Stacie L.;
Perkins, Timothy N.;
Spiess, Page C.;
van der Vliet, Albert;
Butnor, Kelly J.;
Shukla, Arti;
Wadsworth, Marilyn;
Landry, Christopher C.;
Mossman, Brooke T.

Publication type:

journal article

Inhaled Asbestos Exacerbates Atherosclerosis in Apolipoprotein E--Deficient Mice via CD4<sup>+</sup> T Cells.

Published in:

Environmental Health Perspectives, 2008, v. 116, n. 9, p. 1218, doi. 10.1289/ehp.11172

By:

Fukagawa, Naomi K.;
Li, Muyao;
Sabo-Attwood, Tara;
Timblin, Cynthia R.;
Butnor, Kelly J.;
Gagne, Jessica;
Steele, Chad;
Taatjes, Douglas J.;
Huber, Sally;
Mossman, Brooke T.

Publication type:

Article

Regulation of differentiation and keratin protein expression by vitamin A in primary cultures of hamster tracheal epithelial cells.

Published in:

Journal of Cellular Physiology, 1990, v. 142, n. 1, p. 21, doi. 10.1002/jcp.1041420104

By:

Edmondson, Susan W.;
Wu, Reen;
Mossman, Brooke T.

Publication type:

Article

Cellular defense mechanisms against asbestos fibers.

Published in:

Frontiers in Public Health, 2025, p. 1, doi. 10.3389/fpubh.2025.1566473

By:

Barlow, Christy A.;
Mossman, Brooke T.

Publication type:

Article

Chromium (VI) inhibits heme oxygenase-1 expression in vivo and in arsenic-exposed human airway epithelial cells.

Published in:

Journal of Cellular Physiology, 2006, v. 209, n. 1, p. 113, doi. 10.1002/jcp.20710

By:

O'Hara, Kimberley A.;
Nemec, Antonia A.;
Alam, Jawed;
Klei, Linda R.;
Mossman, Brooke T.;
Barchowsky, Aaron

Publication type:

Article

Age affects ERK1/2 and NRF2 signaling in the regulation of GCLC expression.

Published in:

Journal of Cellular Physiology, 2006, v. 208, n. 1, p. 253, doi. 10.1002/jcp.20654

By:

Muyao Li;
Rui-Ming Liu;
Timblin, Cynthia R.;
Meyer, Suzanne G.;
Mossman, Brooke T.;
Fukagawa, Naomi K.

Publication type:

Article

Age affects ERK1/2 and NRF2 signaling in the regulation of GCLC expression.

Published in:

Journal of Cellular Physiology, 2006, v. 206, n. 2, p. 518, doi. 10.1002/jcp.20496

By:

Muyao Li;
Rui-Ming Liu;
Timblin, Cynthia R.;
Meyer, Suzanne G.;
Mossman, Brooke T.;
Fukagawa, Naomi K.

Publication type:

Article