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Scoring the tumor-stroma ratio in colon cancer: procedure and recommendations.
Published in:
2018
By:
- van Pelt, G. W.;
- Kjær-Frifeldt, S.;
- van Krieken, J. H. J. M.;
- Al Dieri, R.;
- Morreau, H.;
- Tollenaar, R. A. E. M.;
- Sørensen, F. B.;
- Mesker, W. E.
Publication type:
journal article
Traumatic air embolism; a case report and literature review of this rare complication of trauma.
Published in:
2024
By:
- Morreau, Jonty H
Publication type:
Case Study
PTEN in colorectal cancer: a report on two Cowden syndrome patients.
Published in:
Clinical Genetics, 2012, v. 81, n. 6, p. 555, doi. 10.1111/j.1399-0004.2011.01639.x
By:
- Kersseboom, R;
- Dubbink, HJ;
- Corver, WE;
- van Tilburg, AJP;
- Poley, JW;
- van Leerdam, ME;
- Atmodimedjo, PN;
- van de Laar, IMBH;
- Collée, JM;
- Dinjens, WNM;
- Morreau, H;
- Wagner, A
Publication type:
Article
Germline mutations in APC and MUTYH are responsible for the majority of families with attenuated familial adenomatous polyposis.
Published in:
Clinical Genetics, 2007, v. 71, n. 5, p. 427, doi. 10.1111/j.1399-0004.2007.00766.x
By:
- Nielsen, M.;
- Hes, F. J.;
- Nagengast, F. M.;
- Weiss, M. M.;
- Mathus-Vliegen, E. M.;
- Morreau, H.;
- Breuning, M. H.;
- Wijnen, J. T.;
- Tops, C. M. J.;
- Vasen, H. F. A.
Publication type:
Article
Identification of HNPCC by molecular analysis of colorectal and endometrial tumors.
Published in:
Disease Markers, 2004, v. 20, n. 4-5, p. 207, doi. 10.1155/2004/391039
By:
- Vasen, H. F. A.;
- Hendriks, Y.;
- de Jong, A. E.;
- van Puijenbroek, M.;
- Tops, C.;
- Bröcker-Vriends, A. H. J. T.;
- Wijnen, J. Th.;
- Morreau, H.
Publication type:
Article
High frequency of copy-neutral LOH in MUTYH-associated polyposis carcinomas.
Published in:
Journal of Pathology, 2008, v. 216, n. 1, p. 25, doi. 10.1002/path.2375
By:
- Middeldorp, A;
- van Puijenbroek, M;
- Nielsen, M;
- Corver, WE;
- Jordanova, ES;
- ter Haar, N;
- Tops, CMJ;
- Vasen, HFA;
- Lips, EH;
- van Eijk, R;
- Hes, FJ;
- Oosting, J;
- Wijnen, J;
- van Wezel, T;
- Morreau, H
Publication type:
Article
Single nucleotide polymorphism array analysis of chromosomal instability patterns discriminates rectal adenomas from carcinomas.
Published in:
Journal of Pathology, 2007, v. 212, n. 3, p. 269, doi. 10.1002/path.2180
By:
- Lips, EH;
- de Graaf, EJ;
- Tollenaar, RAEM;
- van Eijk, R;
- Oosting, J;
- Szuhai, K;
- Karsten, T;
- Nanya, Y;
- Ogawa, S;
- van de Velde, CJ;
- Eilers, PHC;
- van Wezel, Tom;
- Morreau, H
Publication type:
Article
Everolimus in Patients With Advanced Follicular-Derived Thyroid Cancer: Results of a Phase II Clinical Trial.
Published in:
2016
By:
- Schneider, T C;
- de Wit, D;
- Links, T P;
- van Erp, N P;
- van der Hoeven, J J M;
- Gelderblom, H;
- Roozen, C F M;
- Bos, M;
- Corver, W E;
- van Wezel, T;
- Smit, J W A;
- Morreau, H;
- Guchelaar, H J;
- Kapiteijn, E;
- Schneider, Tatiana C;
- de Wit, Djoeke;
- Links, Thera P;
- van Erp, Nielka P;
- van der Hoeven, Jakobus J M;
- Gelderblom, Hans
Publication type:
journal article
Safety and efficacy of the addition of simvastatin to cetuximab in previously treated KRAS mutant metastatic colorectal cancer patients.
Published in:
Investigational New Drugs, 2015, v. 33, n. 6, p. 1242, doi. 10.1007/s10637-015-0285-8
By:
- Baas, J.;
- Krens, L.;
- Tije, A.;
- Erdkamp, F.;
- Wezel, T.;
- Morreau, H.;
- Gelderblom, H.;
- Guchelaar, H.
Publication type:
Article
Colibactin mutational signatures in NTHL1 tumor syndrome and MUTYH associated polyposis patients.
Published in:
Genes, Chromosomes & Cancer, 2024, v. 63, n. 1, p. 1, doi. 10.1002/gcc.23208
By:
- Terlouw, D.;
- Boot, A.;
- Ducarmon, Q. R.;
- Nooij, S.;
- Jessurun, M. A.;
- van Leerdam, M. E.;
- Tops, C. M.;
- Langers, A. M. J.;
- Morreau, H.;
- van Wezel, T.;
- Nielsen, M.
Publication type:
Article
Dendritic cells in colorectal cancer correlate with other tumor-infiltrating immune cells.
Published in:
Cancer Immunology, Immunotherapy, 2004, v. 53, n. 11, p. 978, doi. 10.1007/s00262-004-0548-2
By:
- Dadabayev, A.R.;
- Sandel, M.H.;
- Menon, A.G.;
- Morreau, H.;
- Melief, C.J.M.;
- Offringa, R.;
- van der Burg, S.H.;
- Janssen-van. Rhijn, C.;
- Ensink, N.G.;
- Tollenaar, R.A.E.M.;
- van de Velde, C.J.H.;
- Kuppen, P.J.K.
Publication type:
Article
Dual role of LOH at MMR loci in hereditary non-polyposis colorectal cancer?
Published in:
Oncogene, 2006, v. 25, n. 14, p. 2124, doi. 10.1038/sj.onc.1209233
By:
- Sanchez de Abajo, A.;
- de la Hoya, M.;
- van Puijenbroek, M.;
- Godino, J.;
- Díaz-Rubio, E.;
- Morreau, H.;
- Caldes, T.
Publication type:
Article
Targetable gene fusions identified in radioactive iodine refractory advanced thyroid carcinoma.
Published in:
European Journal of Endocrinology, 2019, v. 180, n. 4, p. 235, doi. 10.1530/EJE-18-0653
By:
- van der Tuin, K.;
- Garcia, M. Ventayol;
- Corver, W. E.;
- Khalifa, M. N.;
- RuanoNeto, D.;
- Corssmit, E. P. M.;
- Hes, F. J.;
- Links, T. P.;
- Smit, J. W. A.;
- Plantinga, T. S.;
- Kapiteijn, E.;
- van Wezel, T.;
- Morreau, H.
Publication type:
Article
Long-term analysis of the efficacy and tolerability of sorafenib in advanced radio-iodine refractory differentiated thyroid carcinoma: final results of a phase II trial.
Published in:
European Journal of Endocrinology, 2012, v. 167, n. 5, p. 643, doi. 10.1530/EJE-12-0405
By:
- Schneider, T. C.;
- Abdulrahman, R. M.;
- Corssmit, E. P.;
- Morreau, H;
- Smit, J. W. A.;
- Kapiteijn, E.
Publication type:
Article
Genetic analysis of a breast-ovarian cancer family, with 7 cases of colorectal cancer linked to BRCA1, fails to support a role for BRCA1 in colorectal tumorigenesis.
Published in:
International Journal of Cancer, 2000, v. 88, n. 5, p. 778, doi. 10.1002/1097-0215(20001201)88:5<778::AID-IJC15>3.0.CO;2-N
By:
- Peelen, T.;
- de Leeuw, W.;
- van Lent, K.;
- Morreau, H.;
- van Eijk, R.;
- van Vliet, M.;
- Wijnen, J.;
- Ligtenberg, M.;
- Ginjaar, H.B.;
- Zweemer, R.;
- Menko, F.;
- Fodde, R.;
- van Ommen, G.-J.B.;
- Vasen, H.F.A.;
- Cornelisse, C.J.;
- Devilee, P.
Publication type:
Article
The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC.
Published in:
British Journal of Cancer, 2015, v. 112, n. 1, p. 122, doi. 10.1038/bjc.2014.560
By:
- Voorneveld, P W;
- Kodach, L L;
- Jacobs, R J;
- van Noesel, C J M;
- Peppelenbosch, M P;
- Korkmaz, K S;
- Molendijk, I;
- Dekker, E;
- Morreau, H;
- van Pelt, G W;
- Tollenaar, R A E M;
- Mesker, W;
- Hawinkels, L J A C;
- Paauwe, M;
- Verspaget, H W;
- Geraets, D T;
- Hommes, D W;
- Offerhaus, G J A;
- van den Brink, G R;
- ten Dijke, P
Publication type:
Article
Clinical prognostic value of combined analysis of Aldh1, Survivin, and EpCAM expression in colorectal cancer.
Published in:
British Journal of Cancer, 2014, v. 110, n. 12, p. 2935, doi. 10.1038/bjc.2014.226
By:
- Goossens-Beumer, I J;
- Zeestraten, E C M;
- Benard, A;
- Christen, T;
- Reimers, M S;
- Keijzer, R;
- Sier, C F M;
- Liefers, G J;
- Morreau, H;
- Putter, H;
- Vahrmeijer, A L;
- van de Velde, C J H;
- Kuppen, P J K
Publication type:
Article
Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosis.
Published in:
2013
By:
- Voorneveld, P W;
- Stache, V;
- Jacobs, R J;
- Smolders, E;
- Sitters, A I;
- Liesker, A;
- S Korkmaz, K;
- Lam, S M;
- De Miranda, N F C C;
- Morreau, H;
- Kodach, L L;
- Hardwick, J C H;
- Korkmaz, K S
Publication type:
journal article
Reduced expression of bone morphogenetic protein receptor IA in pancreatic cancer is associated with a poor prognosis.
Published in:
British Journal of Cancer, 2013, v. 109, n. 7, p. 1805, doi. 10.1038/bjc.2013.486
By:
- Voorneveld, P W;
- Stache, V;
- Jacobs, R J;
- Smolders, E;
- Sitters, A I;
- Liesker, A;
- S Korkmaz, K;
- Lam, S M;
- De Miranda, N F C C;
- Morreau, H;
- Kodach, L L;
- Hardwick, J C H
Publication type:
Article
Molecular alterations associated with liver metastases development in colorectal cancer patients.
Published in:
2011
By:
- Bruin, S. C.;
- He, Y.;
- Mikolajewska-Hanclich, I.;
- Liefers, G.-J.;
- Klijn, C.;
- Vincent, A.;
- Verwaal, V. J.;
- de Groot, K. A.;
- Morreau, H.;
- van Velthuysen, M.-L. F.;
- Tollenaar, R. A. E. M.;
- van 't Veer, L. J.
Publication type:
journal article
COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer.
Published in:
2010
By:
- Tomlinson, I. P. M.;
- Dunlop, M.;
- Campbell, H.;
- Zanke, B.;
- Gallinger, S.;
- Hudson, T.;
- Koessler, T.;
- Pharoah, P. D.;
- Niittymäkix, I.;
- Tuupanenx, S.;
- Aaltonen, L. A.;
- Hemminki, K.;
- Lindblom, A.;
- Försti, A.;
- Sieber, O.;
- Lipton, L.;
- van Wezel, T.;
- Morreau, H.;
- Wijnen, J. T.;
- Devilee, P.
Publication type:
journal article
COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer.
Published in:
2010
By:
- Tomlinson, I P M;
- Dunlop, M;
- Campbell, H;
- Zanke, B;
- Gallinger, S;
- Hudson, T;
- Koessler, T;
- Pharoah, P D;
- Niittymäki, I;
- Tuupanen, S;
- Aaltonen, L A;
- Hemminki, K;
- Lindblom, A;
- Försti, A;
- Sieber, O;
- Lipton, L;
- van Wezel, T;
- Morreau, H;
- Wijnen, J T;
- Devilee, P
Publication type:
Correction Notice
Increased frequency of 20q gain and copy-neutral loss of heterozygosity in mismatch repair proficient familial colorectal carcinomas.
Published in:
International Journal of Cancer, 2012, v. 130, n. 4, p. 837, doi. 10.1002/ijc.26093
By:
- Middeldorp, A.;
- van Eijk, R.;
- Oosting, J.;
- Forte, G.I.;
- van Puijenbroek, M.;
- van Nieuwenhuizen, M.;
- Corver, W.E.;
- Ruano, D.;
- Caldes, T.;
- Wijnen, J.;
- Morreau, H.;
- van Wezel, T.
Publication type:
Article
A unique case of two somatic APC mutations in an early onset cribriform-morular variant of papillary thyroid carcinoma and overview of the literature.
Published in:
Familial Cancer, 2020, v. 19, n. 1, p. 15, doi. 10.1007/s10689-019-00146-4
By:
- Aydemirli, M. D.;
- van der Tuin, K.;
- Hes, F. J.;
- van den Ouweland, A. M. W.;
- van Wezel, T.;
- Kapiteijn, E.;
- Morreau, H.
Publication type:
Article
Academia-pharma intersect: gastrointestinal cancer. Prognostic and predictive biomarkers in resected colon cancer: current status and future perspectives for integrating genomics into biomarker discovery.
Published in:
2010
By:
- Tejpar S;
- Bertagnolli M;
- Bosman F;
- Lenz H;
- Garraway L;
- Waldman F;
- Warren R;
- Bild A;
- Collins-Brennan D;
- Hahn H;
- Harkin DP;
- Kennedy R;
- Ilyas M;
- Morreau H;
- Proutski V;
- Swanton C;
- Tomlinson I;
- DeLorenzi M;
- Fiocca R;
- Van Cutsem E
Publication type:
Journal Article
Identification of MEN1 and HRPT2 somatic mutations in paraffin-embedded (sporadic) parathyroid carcinomas.
Published in:
Clinical Endocrinology, 2007, v. 67, n. 3, p. 370, doi. 10.1111/j.1365-2265.2007.02894.x
By:
- Haven, C. J.;
- van Puijenbroek, M.;
- Tan, M. H.;
- Teh, B. T.;
- Fleuren, G. J.;
- van Wezel, T.;
- Morreau, H.
Publication type:
Article
COGENT (COlorectal Cancer GENeTics): An International Consortium To Study The Role Of Polymorphic Variation On The Risk Of Colorectal Cancer.
Published in:
Asia-Pacific Journal of Oncological Medicine, 2010, v. 2, n. 1, p. 100, doi. 10.5083/apjom.20424965.19
By:
- Tomlinson, I. P. M.;
- Dunlop, M.;
- Campbell, H.;
- Zanke, B.;
- Gallinger, S.;
- Hudson, T.;
- Koessler, T.;
- Pharoah, P. D.;
- Niittymäkix, I.;
- Tuupanenx, S.;
- Aaltonen, L. A.;
- Hemminki, K.;
- Lindblom, A.;
- Försti, A.;
- Sieber, O.;
- Lipton, L.;
- Wezel, T. van;
- Morreau, H.;
- Wijnen, J. T.;
- Devilee, P.
Publication type:
Article
Integrating chromosomal aberrations and gene expression profiles to dissect rectal tumorigenesis.
Published in:
2008
By:
- Lips EH;
- van Eijk R;
- de Graaf EJ;
- Oosting J;
- de Miranda NF;
- Karsten T;
- van de Velde CJ;
- Eilers PH;
- Tollenaar RA;
- van Wezel T;
- Morreau H
Publication type:
Journal Article

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