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Evidence that a STAT3 Mutation Causing Hyper IgE Syndrome Leads to Repression of Transcriptional Activity.
- Published in:
- Case Reports in Immunology, 2019, p. 1, doi. 10.1155/2019/1869524
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- Publication type:
- Article
Images From the Exeter Archival Diabetes Biobank Now Accessible via Pancreatlas.
- Published in:
- Diabetes Care, 2022, v. 45, n. 12, p. e174, doi. 10.2337/dc22-1613
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- Article
C-Peptide Decline in Type 1 Diabetes Has Two Phases: An Initial Exponential Fall and a Subsequent Stable Phase.
- Published in:
- 2018
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- Publication type:
- journal article
Preparation of analogues of efaroxan and KU14R as potential imidazoline receptor subtype 3 ligands.
- Published in:
- Journal of Heterocyclic Chemistry, 2008, v. 45, n. 3, p. 887, doi. 10.1002/jhet.5570450338
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- Publication type:
- Article
Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells.
- Published in:
- eLife, 2015, p. 1, doi. 10.7554/eLife.06990
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- Publication type:
- Article
An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16327-0
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- Publication type:
- Article
Reduced Expression of the Co-regulator TLE1 in Type 2 Diabetes Is Associated with Increased Islet α-Cell Number.
- Published in:
- Endocrinology, 2020, v. 161, n. 4, p. 1, doi. 10.1210/endocr/bqaa011
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- Publication type:
- Article
Type 1 Diabetes: Interferons and the Aftermath of Pancreatic Beta-Cell Enteroviral Infection.
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- Microorganisms, 2020, v. 8, n. 9, p. 1419, doi. 10.3390/microorganisms8091419
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- Article
Differential expression of genes controlling lymphocyte differentiation and migration in two distinct endotypes of type 1 diabetes.
- Published in:
- Diabetic Medicine, 2023, v. 40, n. 9, p. 1, doi. 10.1111/dme.15155
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- Article
Expression of CD47 in the pancreatic β‐cells of people with recent‐onset type 1 diabetes varies according to disease endotype.
- Published in:
- Diabetic Medicine, 2021, v. 38, n. 12, p. 1, doi. 10.1111/dme.14724
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- Article
Immunopathology of the human pancreas in type-I diabetes.
- Published in:
- Seminars in Immunopathology, 2011, v. 33, n. 1, p. 9, doi. 10.1007/s00281-010-0205-0
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- Publication type:
- Article
Differential routing and disposition of the long-chain saturated fatty acid palmitate in rodent vs human beta-cells.
- Published in:
- Nutrition & Diabetes, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41387-022-00199-y
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- Publication type:
- Article
Spatiotemporal Dynamics of Insulitis in Human Type 1 Diabetes.
- Published in:
- Frontiers in Physiology, 2016, v. 7, p. 1, doi. 10.3389/fphys.2016.00633
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- Publication type:
- Article
Footprints of Immune Cells in the Pancreas in Type 1 Diabetes; to "B" or Not to "B": Is That Still the Question?
- Published in:
- Frontiers in Endocrinology, 2021, v. 11, p. N.PAG, doi. 10.3389/fendo.2021.617437
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- Publication type:
- Article
Islet inflammation in human type 1 diabetes mellitus.
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- IUBMB Life, 2014, v. 66, n. 11, p. 723, doi. 10.1002/iub.1330
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- Article
How, When, and Where Do Human β-Cells Regenerate?
- Published in:
- 2019
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- Publication type:
- journal article
HLA Class I Upregulation and Antiviral Immune Responses in Graves Disease.
- Published in:
- 2021
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- Publication type:
- journal article
Comparative Effects of Efaroxan and b-Carbolines on the Secretory Activity of Rodent and Human b Cells.
- Published in:
- Annals of the New York Academy of Sciences, 2004, v. 1009, n. 1, p. 167, doi. 10.1196/annals.1304.019
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- Publication type:
- Article
Identification of high-performing antibodies for the reliable detection of Tau proteoforms by Western blotting and immunohistochemistry.
- Published in:
- Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-024-02729-7
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- Publication type:
- Article
Upregulation of HLA Class I and Antiviral Tissue Responses in Hashimoto's Thyroiditis.
- Published in:
- Thyroid, 2020, v. 30, n. 3, p. 432, doi. 10.1089/thy.2019.0607
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- Article
The role of the interferon/JAK-STAT axis in driving islet HLA-I hyperexpression in type 1 diabetes.
- Published in:
- Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1270325
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- Publication type:
- Article
Offspring of Mice Exposed to a Low-Protein Diet in Utero Demonstrate Changes in mTOR Signaling in Pancreatic Islets of Langerhans, Associated with Altered Glucagon and Insulin Expression and a Lower β-Cell Mass.
- Published in:
- Nutrients, 2019, v. 11, n. 3, p. 605, doi. 10.3390/nu11030605
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- Publication type:
- Article
Structure–activity relationships influencing lipid-induced changes in eIF2α phosphorylation and cell viability in BRIN-BD11 cells
- Published in:
- FEBS Letters, 2011, v. 585, n. 14, p. 2243, doi. 10.1016/j.febslet.2011.05.045
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- Publication type:
- Article
Regulation of STAT1 Signaling in Human Pancreatic β-Cells by the Lysine Deacetylase HDAC6: A New Therapeutic Opportunity in Type 1 Diabetes?
- Published in:
- Diabetes, 2024, v. 73, n. 9, p. 1473, doi. 10.2337/db24-0008
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- Publication type:
- Article
Circulating C-Peptide Levels in Living Children and Young People and Pancreatic β-Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration.
- Published in:
- 2022
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- Publication type:
- journal article
Altered β-Cell Prohormone Processing and Secretion in Type 1 Diabetes.
- Published in:
- Diabetes, 2021, v. 70, n. 5, p. 1038, doi. 10.2337/dbi20-0034
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- Publication type:
- Article
HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes.
- Published in:
- 2019
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- Publication type:
- journal article
Molecular Pathways for Immune Recognition of Preproinsulin Signal Peptide in Type 1 Diabetes.
- Published in:
- 2018
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- Publication type:
- journal article
Preparation of novel 2-(benzo[ b]furan-2-yl)-1 H-imidazolines for photoaffinity labelling and affinity isolation of imidazoline binding.
- Published in:
- Journal of Heterocyclic Chemistry, 2001, v. 38, n. 2, p. 519, doi. 10.1002/jhet.5570380237
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- Publication type:
- Article
The Beneficial Effects of n-3 Polyunsaturated Fatty Acids on Diet Induced Obesity and Impaired Glucose Control Do Not Require Gpr120.
- Published in:
- PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114942
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- Article
In Situ Analysis Reveals That CFTR Is Expressed in Only a Small Minority of β-Cells in Normal Adult Human Pancreas.
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- 2019
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- Publication type:
- journal article
Developmentally dynamic changes in DNA methylation in the human pancreas.
- Published in:
- BMC Genomics, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s12864-024-10450-8
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- Article
Imidazolines and Pancreatic Hormone Secretion<sup>a</sup>.
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- Annals of the New York Academy of Sciences, 1999, v. 881, n. 1, p. 217, doi. 10.1111/j.1749-6632.1999.tb09364.x
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- Publication type:
- Article
Pancreatic β-Cells Express an Imidazoline Binding Site That Is Distinct from I<sub>1</sub> and I<sub>2</sub> Sites<sup>fn1</sup>.
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- Annals of the New York Academy of Sciences, 1995, v. 763, n. 1, p. 153, doi. 10.1111/j.1749-6632.1995.tb32400.x
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- Publication type:
- Article
Characterization of the Imidazoline Binding Site Involved in Regulation of Insulin Secretion<sup>fn1</sup>.
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- Annals of the New York Academy of Sciences, 1995, v. 763, n. 1, p. 361, doi. 10.1111/j.1749-6632.1995.tb32424.x
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- Article
Investigation of the utility of the 1.1B4 cell as a model human beta cell line for study of persistent enteroviral infection.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-94878-y
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- Publication type:
- Article
Human and rodent pancreatic β-cells express IL-4 receptors and IL-4 protects against β-cell apoptosis by activation of the PI3K and JAK/STAT pathways.
- Published in:
- Bioscience Reports, 2010, v. 30, n. 3, p. 169, doi. 10.1042/BSR20090021
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- Article
Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes.
- Published in:
- 2016
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- Publication type:
- journal article
Detection of a Low-Grade Enteroviral Infection in the Islets of Langerhans of Living Patients Newly Diagnosed With Type 1 Diabetes.
- Published in:
- Diabetes, 2015, v. 64, n. 5, p. 1682, doi. 10.2337/db14-1370
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- Publication type:
- Article
Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes.
- Published in:
- Diabetes, 2014, v. 63, n. 11, p. 3835, doi. 10.2337/db14-0365
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- Publication type:
- Article
A Kir6.2 Mutation Causing Neonatal Diabetes Impairs Electrical Activity and Insulin Secretion From INS-1 β-Cells.
- Published in:
- Diabetes, 2006, v. 55, n. 11, p. 3075, doi. 10.2337/db06-0637
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- Publication type:
- Article
Characterization of a KATP channel-independent pathway involved in potentiation of insulin secretion by efaroxan.
- Published in:
- 2001
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- Publication type:
- journal article
Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1beta and Fas ligation.
- Published in:
- 1998
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- Publication type:
- journal article
Long-chain saturated fatty acid species are not toxic to human pancreatic β-cells and may offer protection against pro-inflammatory cytokine induced β-cell death.
- Published in:
- Nutrition & Metabolism, 2021, v. 18, n. 1, p. 1, doi. 10.1186/s12986-021-00541-8
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- Publication type:
- Article
Long-chain saturated fatty acid species are not toxic to human pancreatic β-cells and may offer protection against pro-inflammatory cytokine induced β-cell death.
- Published in:
- Nutrition & Metabolism, 2021, v. 18, n. 1, p. 1, doi. 10.1186/s12986-021-00541-8
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- Publication type:
- Article
Interferons are key cytokines acting on pancreatic islets in type 1 diabetes.
- Published in:
- Diabetologia, 2024, v. 67, n. 5, p. 908, doi. 10.1007/s00125-024-06106-7
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- Publication type:
- Article
Gene expression profiling in NOD mice reveals that B cells are highly educated by the pancreatic environment during autoimmune diabetes.
- Published in:
- Diabetologia, 2023, v. 66, n. 3, p. 551, doi. 10.1007/s00125-022-05839-7
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- Publication type:
- Article
Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage.
- Published in:
- Diabetologia, 2022, v. 65, n. 10, p. 1701, doi. 10.1007/s00125-022-05753-y
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- Publication type:
- Article
Identification and characterisation of tertiary lymphoid organs in human type 1 diabetes.
- Published in:
- Diabetologia, 2021, v. 64, n. 7, p. 1626, doi. 10.1007/s00125-021-05453-z
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- Article
Studies of insulin and proinsulin in pancreas and serum support the existence of aetiopathological endotypes of type 1 diabetes associated with age at diagnosis.
- Published in:
- Diabetologia, 2020, v. 63, n. 6, p. 1258, doi. 10.1007/s00125-020-05115-6
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- Publication type:
- Article