Works matching AU Morello, Roy

Results: 27

A new Col1a1 conditional knock-in mouse model to study osteogenesis imperfecta.

Published in:

Journal of Bone & Mineral Research, 2025, v. 40, n. 1, p. 114, doi. 10.1093/jbmr/zjae189

By:

Dimori, Milena;
Toulany, Mahtab;
Sultana, Lira Samia;
Onal, Melda;
Thostenson, Jeff D;
Carroll, John L;
O'Brien, Charles A;
Morello, Roy

Publication type:

Article

CRTAP and LEPRE1 mutations in recessive osteogenesis imperfecta.

Published in:

Human Mutation, 2008, v. 29, n. 12, p. 1435, doi. 10.1002/humu.20799

By:

Baldridge, Dustin;
Schwarze, Ulrike;
Morello, Roy;
Lennington, Jennifer;
Bertin, Terry K.;
Pace, James M.;
Pepin, Melanie G.;
Weis, MaryAnn;
Eyre, David R.;
Walsh, Jennifer;
Lambert, Deborah;
Green, Andrew;
Robinson, Haynes;
Michelson, Melonie;
Houge, Gunnar;
Lindman, Carl;
Martin, Judith;
Ward, Jewell;
Lemyre, Emmanuelle;
Mitchell, John J.

Publication type:

Article

The Osteocyte Transcriptome Is Extensively Dysregulated in Mouse Models of Osteogenesis Imperfecta.

Published in:

JBMR Plus, 2019, v. 3, n. 7, p. N.PAG, doi. 10.1002/jbm4.10171

By:

Zimmerman, Sarah M;
Dimori, Milena;
Heard‐Lipsmeyer, Melissa E;
Morello, Roy

Publication type:

Article

Haploinsufficiency of Col5a1 causes intrinsic lung and respiratory changes in a mouse model of classical Ehlers‐Danlos syndrome.

Published in:

Physiological Reports, 2022, v. 10, n. 8, p. 1, doi. 10.14814/phy2.15275

By:

Fett, Jordan;
Dimori, Milena;
Carroll, John L.;
Morello, Roy

Publication type:

Article

Regulation of glomerular basement membrane collagen expression by LMX1B contributes to renal disease in nail patella syndrome.

Published in:

Nature Genetics, 2001, v. 27, n. 2, p. 205, doi. 10.1038/84853

By:

Morello, Roy;
Zhou, Guang;
Dreyer, Sandra D.;
Harvey, Scott J.;
Ninomiya, Yoshifumi;
Thorner, Paul S.;
Miner, Jeffrey H.;
Cole, William;
Winterpacht, Andreas;
Zabel, Bernhard;
Oberg, Kerby C.;
Lee, Brendan

Publication type:

Article

A Rab33b missense mouse model for Smith-McCort dysplasia shows bone resorption defects and altered protein glycosylation.

Published in:

Frontiers in Genetics, 2023, p. 01, doi. 10.3389/fgene.2023.1204296

By:

Dimori, Milena;
Pokrovskaya, Irina D.;
Shijie Liu;
Sherrill, John T.;
Gomez-Acevedo, Horacio;
Qiang Fu;
Storrie, Brian;
Lupashin, Vladimir V.;
Morello, Roy

Publication type:

Article

Generalized Connective Tissue Disease in Crtap-/- Mouse.

Published in:

PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010560

By:

Baldridge, Dustin;
Lennington, Jennifer;
Weis, MaryAnn;
Homan, Erica P.;
Ming-Ming Jiang;
Munivez, Elda;
Keene, Douglas R.;
Hogue, William R.;
Pyott, Shawna;
Byers, Peter H.;
Krakow, Deborah;
Cohn, Daniel H.;
Eyre, David R.;
Lee, Brendan;
Morello, Roy

Publication type:

Article

RXFP2 Small Molecule Agonists: Potential Therapeutics for Osteoporosis.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2398

By:

Esteban‐Lopez, Maria;
Wilson, Kenneth;
Myhr, Courtney;
Kaftanovskaya, Elena;
Henderson, Mark;
Southall, Noel;
Hu, Xin;
Barnaeva, Elena;
Ferrer, Marc;
Kim, David;
Ye, Wenjuan;
Morello, Roy;
Agoulnik, Irina;
Marugan, Juan;
Agoulnik, Alexander

Publication type:

Article

The NAD salvage pathway in mesenchymal cells is indispensable for skeletal development in mice.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39392-7

By:

Warren, Aaron;
Porter, Ryan M.;
Reyes-Castro, Olivia;
Ali, Md Mohsin;
Marques-Carvalho, Adriana;
Kim, Ha-Neui;
Gatrell, Landon B.;
Schipani, Ernestina;
Nookaew, Intawat;
O'Brien, Charles A.;
Morello, Roy;
Almeida, Maria

Publication type:

Article

Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation.

Published in:

PLoS Genetics, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.pgen.1006002

By:

Heard, Melissa E.;
Besio, Roberta;
Weis, MaryAnn;
Rai, Jyoti;
Hudson, David M.;
Dimori, Milena;
Zimmerman, Sarah M.;
Kamykowski, Jeffrey A.;
Hogue, William R.;
Swain, Frances L.;
Burdine, Marie S.;
Mackintosh, Samuel G.;
Tackett, Alan J.;
Suva, Larry J.;
Eyre, David R.;
Morello, Roy

Publication type:

Article

LMX1B transactivation and expression in nail-patella syndrome.

Published in:

Human Molecular Genetics, 2000, v. 9, n. 7, p. 1067, doi. 10.1093/hmg/9.7.1067

By:

Dreyer, Sandra D.;
Morello, Roy;
German, Michael S.;
Zabel, Bernhard;
Winterpacht, Andreas;
Lunstrum, Gregory P.;
Horton, William A.;
Oberg, Kerby C.;
Lee, Brendan

Publication type:

Article

Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome.

Published in:

Human Molecular Genetics, 2008, v. 17, n. 14, p. 2244, doi. 10.1093/hmg/ddn125

By:

Napierala, Dobrawa;
Sam, Kathy;
Morello, Roy;
Zheng, Qiping;
Munivez, Elda;
Shivdasani, Ramesh A.;
Lee, Brendan

Publication type:

Article

Extensive Remineralization of Large Pelvic Lytic Lesions Following Total Therapy Treatment in Patients With Multiple Myeloma.

Published in:

Journal of Bone & Mineral Research, 2017, v. 32, n. 6, p. 1261, doi. 10.1002/jbmr.3111

By:

Mohan, Meera;
Samant, Rohan S;
Yoon, Donghoon;
Buros, Amy F;
Branca, Antonio;
Montgomery, Corey O;
Nicholas, Richard;
Suva, Larry J;
Morello, Roy;
Thanendrarajan, Sharmilan;
Schinke, Carolina;
Yaccoby, Shmuel;
van Rhee, Frits;
Davies, Faith E;
Morgan, Gareth J;
Zangari, Maurizio

Publication type:

Article

Sc65 Is a Novel Endoplasmic Reticulum Protein That Regulates Bone Mass Homeostasis.

Published in:

Journal of Bone & Mineral Research, 2014, v. 29, n. 3, p. 666, doi. 10.1002/jbmr.2075

By:

Gruenwald, Katrin;
Castagnola, Patrizio;
Besio, Roberta;
Dimori, Milena;
Chen, Yuqing;
Akel, Nisreen S;
Swain, Frances L;
Skinner, Robert A;
Eyre, David R;
Gaddy, Dana;
Suva, Larry J;
Morello, Roy

Publication type:

Article

Mutations in SERPINF1 cause osteogenesis imperfecta type VI.

Published in:

Journal of Bone & Mineral Research, 2011, v. 26, n. 12, p. 2798, doi. 10.1002/jbmr.487

By:

Homan, Erica P;
Rauch, Frank;
Grafe, Ingo;
Lietman, Caressa;
Doll, Jennifer A;
Dawson, Brian;
Bertin, Terry;
Napierala, Dobrawa;
Morello, Roy;
Gibbs, Richard;
White, Lisa;
Miki, Rika;
Cohn, Daniel H;
Crawford, Susan;
Travers, Rose;
Glorieux, Francis H;
Lee, Brendan

Publication type:

Article

Mutations in the Insulin-Like Factor 3 Receptor Are Associated With Osteoporosis.

Published in:

Journal of Bone & Mineral Research, 2008, v. 23, n. 5, p. 683, doi. 10.1359/JBMR.080204

By:

Ferlin, Alberto;
Pepe, Anastasia;
Gianesello, Lisa;
Garolla, Andrea;
Shu Fen;
Giannini, Sandro;
Zaccolo, Manuela;
Facciolli, Arianna;
Morello, Roy;
Agoulnik, Alexander I.;
Foresta, Carlo

Publication type:

Article

The nuclear genes Mtfr1 and Dufd1 regulate mitochondrial dynamic and cellular respiration.

Published in:

Journal of Cellular Physiology, 2010, v. 225, n. 3, p. 767, doi. 10.1002/jcp.22279

By:

MONTICONE, MASSIMILIANO;
PANFOLI, ISABELLA;
RAVERA, SILVIA;
PUGLISI, ROSSELLA;
MING-MING JIANG;
MORELLO, ROY;
CANDIANI, SIMONA;
TONACHINI, LAURA;
BITICCHI, ROBERTA;
FABIANO, ANDREA;
CANCEDDA, RANIERI;
BOITANI, CARLA;
CASTAGNOLA, PATRIZIO

Publication type:

Article

Brachy–syndactyly caused by loss of Sfrp2 function.

Published in:

Journal of Cellular Physiology, 2008, v. 217, n. 1, p. 127, doi. 10.1002/jcp.21483

By:

Morello, Roy;
Bertin, Terry K.;
Schlaubitz, Silke;
Shaw, Chad A.;
Kakuru, Sujatha;
Munivez, Elda;
Hermanns, Pia;
Yuqing Chen;
Zabel, Bernhard;
Lee, Brendan

Publication type:

Article

Distinct type I collagen alterations cause intrinsic lung and respiratory defects of variable severity in mouse models of osteogenesis imperfecta.

Published in:

Journal of Physiology, 2023, v. 601, n. 2, p. 355, doi. 10.1113/JP283452

By:

Dimori, Milena;
Fett, Jordan;
Leikin, Sergey;
Otsuru, Satoru;
Thostenson, Jeff D.;
Carroll, John L.;
Morello, Roy

Publication type:

Article

The Osteocyte Transcriptome: Discovering Messages Buried Within Bone.

Published in:

Current Osteoporosis Reports, 2021, v. 19, n. 6, p. 604, doi. 10.1007/s11914-021-00708-5

By:

Wee, Natalie KY;
Sims, Natalie A;
Morello, Roy

Publication type:

Article

Modeling Rare Bone Diseases in Animals.

Published in:

Current Osteoporosis Reports, 2018, v. 16, n. 4, p. 458, doi. 10.1007/s11914-018-0452-x

By:

O’Brien, Charles A.;
Morello, Roy

Publication type:

Article

Role of Cartilage-Associated Protein in Skeletal Development.

Published in:

Current Osteoporosis Reports, 2010, v. 8, n. 2, p. 77, doi. 10.1007/s11914-010-0010-7

By:

Morello, Roy;
Rauch, Frank

Publication type:

Article

Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-04143-9

By:

Esteban-Lopez, Maria;
Wilson, Kenneth J.;
Myhr, Courtney;
Kaftanovskaya, Elena M.;
Henderson, Mark J.;
Southall, Noel T.;
Xu, Xin;
Wang, Amy;
Hu, Xin;
Barnaeva, Elena;
Ye, Wenjuan;
George, Emmett R.;
Sherrill, John T.;
Ferrer, Marc;
Morello, Roy;
Agoulnik, Irina U.;
Marugan, Juan J.;
Agoulnik, Alexander I.

Publication type:

Article

Type X collagen gene regulation by Runx2 contributes directly to its hypertrophic chondrocyte—specific expression in vivo.

Published in:

Journal of Cell Biology, 2003, v. 162, n. 5, p. 833, doi. 10.1083/jcb.200211089

By:

Qiping Zheng;
Guang Zhou;
Morello, Roy;
Yuqing Chen;
Garcia-Rojas, Xavier;
Lee, Brendan

Publication type:

Article

New Roles for INSL3 in Adults.

Published in:

Annals of the New York Academy of Sciences, 2009, v. 1160, p. 215, doi. 10.1111/j.1749-6632.2008.03787.x

By:

Ferlin, Alberto;
Pepe, Anastasia;
Gianesello, Lisa;
Garolla, Andrea;
Feng, Shu;
Facciolli, Arianna;
Morello, Roy;
Agoulnik, Alexander I.;
Foresta, Carlo

Publication type:

Article

Dental and craniofacial defects in the Crtap<sup>−/−</sup> mouse model of osteogenesis imperfecta type VII.

Published in:

Developmental Dynamics, 2020, v. 249, n. 7, p. 884, doi. 10.1002/dvdy.166

By:

Xu, He;
Lenhart, Sydney A.;
Chu, Emily Y.;
Chavez, Michael B.;
Wimer, Helen F.;
Dimori, Milena;
Somerman, Martha J.;
Morello, Roy;
Foster, Brian L.;
Hatch, Nan E.

Publication type:

Article

Differential Effects of Collagen Prolyl 3-Hydroxylation on Skeletal Tissues.

Published in:

PLoS Genetics, 2014, v. 10, n. 1, p. 1, doi. 10.1371/journal.pgen.1004121

By:

Homan, Erica P.;
Lietman, Caressa;
Grafe, Ingo;
Lennington, Jennifer;
Morello, Roy;
Napierala, Dobrawa;
Jiang, Ming-Ming;
Munivez, Elda M.;
Dawson, Brian;
Bertin, Terry K.;
Chen, Yuqing;
Lua, Rhonald;
Lichtarge, Olivier;
Hicks, John;
Weis, Mary Ann;
Eyre, David;
Lee, Brendan H. L.

Publication type:

Article