Works by Mordyl, Barbara

Results: 15

Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 6, p. 1, doi. 10.1002/anie.202420510

By:

Panek, Dawid;
Pasieka, Anna;
Jończyk, Jakub;
Gawlińska, Milena;
Zaręba, Paula;
Siwek, Agata;
Wolak, Małgorzata;
Mordyl, Barbara;
Głuch‐Lutwin, Monika;
Latacz, Gniewomir;
Brazzolotto, Xavier;
Chantegreil, Fabien;
Nachon, Florian;
Zdarova Karasova, Jana;
Pejchal, Jaroslav;
Mzik, Martin;
Sestak, Vit;
Prchal, Lukas;
Odvarkova, Jitka;
Soukup, Ondrej

Publication type:

Article

Arylpiperazinylalkyl derivatives of 8-amino-1,3-dimethylpurine-2,6-dione as novel multitarget 5-HT/D receptor agents with potential antipsychotic activity.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1048, doi. 10.3109/14756366.2015.1088844

By:

Chłoń-Rzepa, Grażyna;
Bucki, Adam;
Kołaczkowski, Marcin;
Partyka, Anna;
Jastrzębska-Więsek, Magdalena;
Satała, Grzegorz;
Bojarski, Andrzej J.;
Kalinowska-Tłuścik, Justyna;
Kazek, Grzegorz;
Mordyl, Barbara;
Głuch-Lutwin, Monika;
Wesołowska, Anna

Publication type:

Article

Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

Published in:

Angewandte Chemie, 2025, v. 137, n. 6, p. 1, doi. 10.1002/ange.202420510

By:

Panek, Dawid;
Pasieka, Anna;
Jończyk, Jakub;
Gawlińska, Milena;
Zaręba, Paula;
Siwek, Agata;
Wolak, Małgorzata;
Mordyl, Barbara;
Głuch‐Lutwin, Monika;
Latacz, Gniewomir;
Brazzolotto, Xavier;
Chantegreil, Fabien;
Nachon, Florian;
Zdarova Karasova, Jana;
Pejchal, Jaroslav;
Mzik, Martin;
Sestak, Vit;
Prchal, Lukas;
Odvarkova, Jitka;
Soukup, Ondrej

Publication type:

Article

Xanthine–Dopamine Hybrid Molecules as Multitarget Drugs with Potential for the Treatment of Neurodegenerative Diseases.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 7, p. 1079, doi. 10.3390/biom13071079

By:

Załuski, Michał;
Karcz, Tadeusz;
Drabczyńska, Anna;
Vielmuth, Christin;
Olejarz-Maciej, Agnieszka;
Głuch-Lutwin, Monika;
Mordyl, Barbara;
Siwek, Agata;
Satała, Grzegorz;
Müller, Christa E.;
Kieć-Kononowicz, Katarzyna

Publication type:

Article

Structure-5-HT Receptor Affinity Relationship in a New Group of 7-Arylpiperazynylalkyl and 7-Tetrahydroisoquinolinylalkyl Derivatives of 8-Amino-1,3-dimethyl-1 H-purine-2,6(3 H,7 H)-dione.

Published in:

Archiv der Pharmazie, 2015, v. 348, n. 4, p. 229, doi. 10.1002/ardp.201400392

By:

Żmudzki, Paweł;
Chłoń ‐ Rzepa, Grażyna;
Bojarski, Andrzej J.;
Zygmunt, Małgorzata;
Kazek, Grzegorz;
Mordyl, Barbara;
Pawłowski, Maciej

Publication type:

Article

Connecting GSK-3β Inhibitory Activity with IKK-β or ROCK-1 Inhibition to Target Tau Aggregation and Neuroinflammation in Alzheimer's Disease—Discovery, In Vitro and In Cellulo Activity of Thiazole-Based Inhibitors.

Published in:

Molecules, 2024, v. 29, n. 11, p. 2616, doi. 10.3390/molecules29112616

By:

Góral, Izabella;
Wichur, Tomasz;
Sługocka, Emilia;
Godyń, Justyna;
Szałaj, Natalia;
Zaręba, Paula;
Głuch-Lutwin, Monika;
Mordyl, Barbara;
Panek, Dawid;
Więckowska, Anna

Publication type:

Article

Milk-Derived Carbon Quantum Dots: Study of Biological and Chemical Properties Provides Evidence of Toxicity.

Published in:

Molecules, 2022, v. 27, n. 24, p. 8728, doi. 10.3390/molecules27248728

By:

Shabbir, Hasan;
Wojtaszek, Konrad;
Rutkowski, Bogdan;
Csapó, Edit;
Bednarski, Marek;
Adamiec, Anita;
Głuch-Lutwin, Monika;
Mordyl, Barbara;
Druciarek, Julia;
Kotańska, Magdalena;
Ozga, Piotr;
Wojnicki, Marek

Publication type:

Article

Modulation of the MOP Receptor (μ Opioid Receptor) by Imidazo[1,2- a ]imidazole-5,6-Diones: In Search of the Elucidation of the Mechanism of Action.

Published in:

Molecules, 2022, v. 27, n. 9, p. 2930, doi. 10.3390/molecules27092930

By:

Straszak, Dominik;
Siwek, Agata;
Głuch-Lutwin, Monika;
Mordyl, Barbara;
Kołaczkowski, Marcin;
Pietrzak, Aldona;
Rahnama-Hezavah, Mansur;
Drop, Bartłomiej;
Matosiuk, Dariusz

Publication type:

Article

Vanadium Complexes with Thioanilide Derivatives of Amino Acids: Inhibition of Human Phosphatases and Specificity in Various Cell Models of Metabolic Disturbances.

Published in:

Pharmaceuticals (14248247), 2024, v. 17, n. 2, p. 229, doi. 10.3390/ph17020229

By:

Kazek, Grzegorz;
Głuch-Lutwin, Monika;
Mordyl, Barbara;
Menaszek, Elżbieta;
Kubacka, Monika;
Jurowska, Anna;
Cież, Dariusz;
Trzewik, Bartosz;
Szklarzewicz, Janusz;
Papież, Monika A.

Publication type:

Article

Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT1A and 5-HT7 Antagonists in Animal Models.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0142499

By:

Pytka, Karolina;
Partyka, Anna;
Jastrzębska-Więsek, Magdalena;
Siwek, Agata;
Głuch-Lutwin, Monika;
Mordyl, Barbara;
Kazek, Grzegorz;
Rapacz, Anna;
Olczyk, Adrian;
Gałuszka, Adam;
Błachuta, Marian;
Waszkielewicz, Anna;
Marona, Henryk;
Sapa, Jacek;
Filipek, Barbara;
Wesołowska, Anna

Publication type:

Article

A Comparison of the Anorectic Effect and Safety of the Alpha2-Adrenoceptor Ligands Guanfacine and Yohimbine in Rats with Diet-Induced Obesity.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0141327

By:

Dudek, Magdalena;
Knutelska, Joanna;
Bednarski, Marek;
Nowiński, Leszek;
Zygmunt, Małgorzata;
Mordyl, Barbara;
Głuch-Lutwin, Monika;
Kazek, Grzegorz;
Sapa, Jacek;
Pytka, Karolina

Publication type:

Article

Antipsychotic- and Anxiolytic-like Properties of a Multimodal Compound JJGW08 in Rodents.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15929, doi. 10.3390/ijms232415929

By:

Żmudzka, Elżbieta;
Lustyk, Klaudia;
Głuch-Lutwin, Monika;
Mordyl, Barbara;
Zakrzewska-Sito, Alicja;
Mierzejewski, Paweł;
Jaśkowska, Jolanta;
Kołaczkowski, Marcin;
Sapa, Jacek;
Pytka, Karolina

Publication type:

Article

The Phenoxyalkyltriazine Antagonists for 5-HT 6 Receptor with Promising Procognitive and Pharmacokinetic Properties In Vivo in Search for a Novel Therapeutic Approach to Dementia Diseases.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10773, doi. 10.3390/ijms221910773

By:

Sudoł, Sylwia;
Cios, Agnieszka;
Jastrzębska-Więsek, Magdalena;
Honkisz-Orzechowska, Ewelina;
Mordyl, Barbara;
Wilczyńska-Zawal, Natalia;
Satała, Grzegorz;
Kucwaj-Brysz, Katarzyna;
Partyka, Anna;
Latacz, Gniewomir;
Olejarz-Maciej, Agnieszka;
Wesołowska, Anna;
Handzlik, Jadwiga

Publication type:

Article

Synthesis, Anticonvulsant and Antinociceptive Activity of New Hybrid Compounds: Derivatives of 3-(3-Methylthiophen-2-yl)-pyrrolidine-2,5-dione.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 16, p. 5750, doi. 10.3390/ijms21165750

By:

Góra, Małgorzata;
Czopek, Anna;
Rapacz, Anna;
Dziubina, Anna;
Głuch-Lutwin, Monika;
Mordyl, Barbara;
Obniska, Jolanta

Publication type:

Article

Antidepressant-like activity and safety profile evaluation of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione derivatives as 5-HT1A receptor partial agonists.

Published in:

PLoS ONE, 2020, v. 15, n. 8, p. 1, doi. 10.1371/journal.pone.0237196

By:

Partyka, Anna;
Zagórska, Agnieszka;
Kotańska, Magdalena;
Walczak, Maria;
Jastrzębska-Więsek, Magdalena;
Knutelska, Joanna;
Bednarski, Marek;
Głuch-Lutwin, Monika;
Mordyl, Barbara;
Janiszewska, Paulina;
Wesołowska, Anna

Publication type:

Article

Works by Mordyl, Barbara

Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

Arylpiperazinylalkyl derivatives of 8-amino-1,3-dimethylpurine-2,6-dione as novel multitarget 5-HT/D receptor agents with potential antipsychotic activity.

Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

Xanthine–Dopamine Hybrid Molecules as Multitarget Drugs with Potential for the Treatment of Neurodegenerative Diseases.

Structure-5-HT Receptor Affinity Relationship in a New Group of 7-Arylpiperazynylalkyl and 7-Tetrahydroisoquinolinylalkyl Derivatives of 8-Amino-1,3-dimethyl-1 H-purine-2,6(3 H,7 H)-dione.

Connecting GSK-3β Inhibitory Activity with IKK-β or ROCK-1 Inhibition to Target Tau Aggregation and Neuroinflammation in Alzheimer's Disease—Discovery, In Vitro and In Cellulo Activity of Thiazole-Based Inhibitors.

Milk-Derived Carbon Quantum Dots: Study of Biological and Chemical Properties Provides Evidence of Toxicity.

Modulation of the MOP Receptor (μ Opioid Receptor) by Imidazo[1,2- a ]imidazole-5,6-Diones: In Search of the Elucidation of the Mechanism of Action.

Vanadium Complexes with Thioanilide Derivatives of Amino Acids: Inhibition of Human Phosphatases and Specificity in Various Cell Models of Metabolic Disturbances.

Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT<sub>1A</sub> and 5-HT<sub>7</sub> Antagonists in Animal Models.

A Comparison of the Anorectic Effect and Safety of the Alpha<sub>2</sub>-Adrenoceptor Ligands Guanfacine and Yohimbine in Rats with Diet-Induced Obesity.

Antipsychotic- and Anxiolytic-like Properties of a Multimodal Compound JJGW08 in Rodents.

The Phenoxyalkyltriazine Antagonists for 5-HT 6 Receptor with Promising Procognitive and Pharmacokinetic Properties In Vivo in Search for a Novel Therapeutic Approach to Dementia Diseases.

Synthesis, Anticonvulsant and Antinociceptive Activity of New Hybrid Compounds: Derivatives of 3-(3-Methylthiophen-2-yl)-pyrrolidine-2,5-dione.

Antidepressant-like activity and safety profile evaluation of 1H-imidazo[2,1-f]purine-2,4(3H,8H)-dione derivatives as 5-HT<sub>1A</sub> receptor partial agonists.