Works by Moody, Christopher J.

Results: 44

Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90.

Published in:

Nature Chemistry, 2013, v. 5, n. 4, p. 307, doi. 10.1038/nchem.1596

By:

Kitson, Russell R. A.;
Chang, Chuan-Hsin;
Xiong, Rui;
Williams, Huw E. L.;
Davis, Adrienne L.;
Lewis, William;
Dehn, Donna L.;
Siegel, David;
Roe, S. Mark;
Prodromou, Chrisostomos;
Ross, David;
Moody, Christopher J.

Publication type:

Article

Diazophosphonates: Effective Surrogates for Diazoalkanes in Pyrazole Synthesis.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 55, p. 13703, doi. 10.1002/chem.202101788

By:

Ruffell, Katie;
Smith, Frances R.;
Green, Michael T.;
Nicolle, Simon M.;
Inman, Martyn;
Lewis, William;
Hayes, Christopher J.;
Moody, Christopher J.

Publication type:

Article

Enantioselective Insertion of Metal Carbenes into NH Bonds: A Potentially Versatile Route to Chiral Amine Derivatives.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 48, p. 9148, doi. 10.1002/anie.200703016

By:

Moody, Christopher J.

Publication type:

Article

From Amino Acids to Heteroaromatics-Thiopeptide Antibiotics, Nature's Heterocyclic Peptides.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 42, p. 7930, doi. 10.1002/anie.200700728

By:

Hughes, Rachael A.;
Moody, Christopher J.

Publication type:

Article

Selective dehydrogenation of tetrahydroisoquinolines in the presence of sulfoxides.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2024, v. 2024, p. 1, doi. 10.24820/ark.5550190.p012.253

By:

Spagna, Francesca;
Moody, Christopher J.

Publication type:

Article

Modulation of the acidity of the 8-carboxamide group in the temozolomide family of antitumor imidazo[5,1-d][1,2,3,5]tetrazines.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2020, v. 2020, p. 36, doi. 10.24820/ark.5550190.p011.182

By:

Summers, Helen S.;
Foreiter, Magdalena B.;
Lewis, William;
Moody, Christopher J.;
Bradshaw, Tracey D.;
Stevens, Malcolm F. G.

Publication type:

Article

The Carbenoid Approach to Peptide Synthesis.

Published in:

Chemistry - A European Journal, 2000, v. 6, n. 12, p. 2160, doi. 10.1002/1521-3765(20000616)6:12<2160::AID-CHEM2160>3.0.CO;2-Y

By:

Buck, Richard T.;
Clarke, Paul A.;
Coe, Diane M.;
Drysdale, Martin J.;
Ferris, Leigh;
Haigh, David;
Moody, Christopher J.;
Pearson, Neil D.;
Swann, Elizabeth

Publication type:

Article

Deep learning image segmentation reveals patterns of UV reflectance evolution in passerine birds.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32586-5

By:

He, Yichen;
Varley, Zoë K.;
Nouri, Lara O.;
Moody, Christopher J. A.;
Jardine, Michael D.;
Maddock, Steve;
Thomas, Gavin H.;
Cooney, Christopher R.

Publication type:

Article

Phenoxy‐ and Phenylamino‐Heterocyclic Quinones: Synthesis and Preliminary Anti‐Pancreatic Cancer Activity.

Published in:

Chemistry & Biodiversity, 2022, v. 19, n. 6, p. 1, doi. 10.1002/cbdv.202101036

By:

Sánchez, Patricio;
Salas, Cristian O.;
Gallardo‐Fuentes, Sebastián;
Villegas, Alondra;
Veloso, Nicolás;
Honores, Jessica;
Inman, Martyn;
Isaacs, Mauricio;
Contreras, Renato;
Moody, Christopher J.;
Cisterna, Jonathan;
Brito, Iván;
Tapia, Ricardo A.

Publication type:

Article

Nitrogen‐Bridged, Natural Product Like Octahydrobenzofurans and Octahydroindoles: Scope and Mechanism of Bridge‐Forming Reductive Amination via Caged Heteroadamantanes.

Published in:

European Journal of Organic Chemistry, 2018, v. 2018, n. 34, p. 4696, doi. 10.1002/ejoc.201800962

By:

Wales, Steven. M.;
Adcock, Holly V.;
Lewis, William;
Hamza, Daniel;
Moody, Christopher J.

Publication type:

Article

Synthesis of Epibatidine Analogues by Pyrrole Diels-Alder Reactions: Rapid Access to Azabicyclo[2.2.1]heptane and 3,8-Diazabicyclo[3.2.1]octane Scaffolds for Library Synthesis.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 1, p. 138, doi. 10.1002/ejoc.201601177

By:

Murray, Alexander T.;
Packard, Emma;
Nortcliffe, Andrew;
Lewis, William;
Hamza, Daniel;
Jones, Geraint;
Moody, Christopher J.

Publication type:

Article

Late‐Stage Functionalization by Chan–Lam Amination: Rapid Access to Potent and Selective Integrin Inhibitors.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 34, p. 7678, doi. 10.1002/chem.202001059

By:

Robinson, Henry;
Oatley, Steven A.;
Rowedder, James E.;
Slade, Pawel;
Macdonald, Simon J. F.;
Argent, Stephen P.;
Hirst, Jonathan D.;
McInally, Thomas;
Moody, Christopher J.

Publication type:

Article

Frontispiece: Synthesis of Highly Substituted 1,2‐Diazetidin‐3‐ones, Small‐Ring Scaffolds for Drug Discovery.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 33, p. 1, doi. 10.1002/chem.201883365

By:

Santos, Marilia S.;
Nortcliffe, Andrew;
Lewis, William;
Bradshaw, Tracey D.;
Moody, Christopher J.

Publication type:

Article

Synthesis of Highly Substituted 1,2‐Diazetidin‐3‐ones, Small‐Ring Scaffolds for Drug Discovery.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 33, p. 8325, doi. 10.1002/chem.201801309

By:

Santos, Marilia S.;
Nortcliffe, Andrew;
Lewis, William;
Bradshaw, Tracey D.;
Moody, Christopher J.

Publication type:

Article

Diastereoselective Synthesis of Highly Substituted, Amino‐ and Pyrrolidino‐Tetrahydrofurans as Lead‐Like Molecular Scaffolds.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 32, p. 8233, doi. 10.1002/chem.201801046

By:

Wales, Steven M.;
Merisor, Elena G.;
Adcock, Holly V.;
Pearce, Christopher A.;
Strutt, Ian R.;
Lewis, William;
Hamza, Daniel;
Moody, Christopher J.

Publication type:

Article

C−H Insertion as a Key Step to Spiro-Oxetanes, Scaffolds for Drug Discovery.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 55, p. 13623, doi. 10.1002/chem.201703746

By:

Nicolle, Simon M.;
Nortcliffe, Andrew;
Bartrum, Hannah E.;
Lewis, William;
Hayes, Christopher J.;
Moody, Christopher J.

Publication type:

Article

Mechanism-Based Inhibition of Quinone Reductase 2 (NQO2): Selectivity for NQO2 over NQO1 and Structural Basis for Flavoprotein Inhibition.

Published in:

ChemBioChem, 2011, v. 12, n. 8, p. 1203, doi. 10.1002/cbic.201100085

By:

Dufour, Marine;
Yan, Chao;
Siegel, David;
Colucci, Marie A.;
Jenner, Matthew;
Oldham, Neil J.;
Gomez, Joe;
Reigan, Philip;
Li, Yazhuo;
De Matteis, Cristina I.;
Ross, David;
Moody, Christopher J.

Publication type:

Article

Cytotoxic and radiosensitising effects of a novel thioredoxin reductase inhibitor in breast cancer.

Published in:

Investigational New Drugs, 2021, v. 39, n. 5, p. 1232, doi. 10.1007/s10637-021-01106-5

By:

Abdullah, Nurul A;
Inman, Martyn;
Moody, Christopher J.;
Storr, Sarah J;
Martin, Stewart G

Publication type:

Article

Synthesis of Indoxylic Acid Esters by Rhodium-catalyzed Carbene N-H Insertion and Thermal Cyclization.

Published in:

Australian Journal of Chemistry, 2014, v. 67, n. 8/9, p. 1211, doi. 10.1071/CH14116

By:

Honey, Mark A.;
Moody, Christopher J.

Publication type:

Article

Amination of Heteroaryl Chlorides: Palladium Catalysis or S<sub>N</sub>Ar in Green Solvents?

Published in:

ChemSusChem, 2013, v. 6, n. 8, p. 1455, doi. 10.1002/cssc.201300239

By:

Walsh, Katie;
Sneddon, Helen F.;
Moody, Christopher J.

Publication type:

Article

Formal Total Synthesis of Diazonamide A by Indole Oxidative Rearrangement.

Published in:

Chemistry - A European Journal, 2016, v. 22, n. 31, p. 10867, doi. 10.1002/chem.201601605

By:

David, Nadège;
Pasceri, Raffaele;
Kitson, Russell R. A.;
Pradal, Alexandre;
Moody, Christopher J.

Publication type:

Article

Back Cover: Formal Total Synthesis of Diazonamide A by Indole Oxidative Rearrangement (Chem. Eur. J. 31/2016).

Published in:

Chemistry - A European Journal, 2016, v. 22, n. 31, p. 11088, doi. 10.1002/chem.201602962

By:

David, Nadège;
Pasceri, Raffaele;
Kitson, Russell R. A.;
Pradal, Alexandre;
Moody, Christopher J.

Publication type:

Article

Alkyl Halide-Free Heteroatom Alkylation and Epoxidation Facilitated by a Recyclable Polymer-Supported Oxidant for the In-Flow Preparation of Diazo Compounds.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 12, p. 4576, doi. 10.1002/chem.201500118

By:

Nicolle, Simon M.;
Hayes, Christopher J.;
Moody, Christopher J.

Publication type:

Article

Potassium N-Iodo p-Toluenesulfonamide (TsNIK, Iodamine-T): A New Reagent for the Oxidation of Hydrazones to Diazo Compounds.

Published in:

Chemistry - A European Journal, 2014, v. 20, n. 15, p. 4420, doi. 10.1002/chem.201304656

By:

Nicolle, Simon M.;
Moody, Christopher J.

Publication type:

Article

Rapid Access to α-Alkoxy and α-Amino Acid Derivatives through Safe Continuous-Flow Generation of Diazoesters.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 35, p. 9586, doi. 10.1002/chem.201101590

By:

Bartrum, Hannah E.;
Blakemore, David C.;
Moody, Christopher J.;
Hayes, Christopher J.

Publication type:

Article

Regioselectivity of the Claisen Rearrangement in meta-Allyloxy Aryl Ketones: An Experimental and Computational Study, and Application in the Synthesis of ( R)-(−)-Pestalotheol D.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 6, p. 1972, doi. 10.1002/chem.201002757

By:

Lucas, Catherine L.;
Lygo, Barry;
Blake, Alexander J.;
Lewis, William;
Moody, Christopher J.

Publication type:

Article

Total Synthesis of the Post-translationally Modified Polyazole Peptide Antibiotic Goadsporin.

Published in:

Angewandte Chemie, 2017, v. 129, n. 11, p. 3115, doi. 10.1002/ange.201612103

By:

Dexter, Hannah L.;
Williams, Huw E. L.;
Lewis, William;
Moody, Christopher J.

Publication type:

Article

Stereoselective Synthesis of Functionalized Pyrrolidines by the Diverted N−H Insertion Reaction of Metallocarbenes with β-Aminoketone Derivatives.

Published in:

Angewandte Chemie, 2016, v. 128, n. 11, p. 3813, doi. 10.1002/ange.201511433

By:

Nicolle, Simon M.;
Lewis, William;
Hayes, Christopher J.;
Moody, Christopher J.

Publication type:

Article

Total Synthesis of the Posttranslationally Modified Polyazole Peptide Antibiotic Plantazolicin A.

Published in:

Angewandte Chemie, 2015, v. 127, n. 50, p. 15362, doi. 10.1002/ange.201507062

By:

Hiroki Wada;
Williams, Huw E. L.;
Moody, Christopher J.

Publication type:

Article

Synthesis and Intracellular Redox Cycling of Natural Quinones and Their Analogues and Identification of Indoleamine-2,3-dioxygenase (IDO) as Potential Target for Anticancer Activity.

Published in:

Angewandte Chemie, 2015, v. 127, n. 30, p. 8864, doi. 10.1002/ange.201503323

By:

Blunt, Christopher E.;
Torcuk, Canan;
Liu, Yang;
Lewis, William;
Siegel, David;
Ross, David;
Moody, Christopher J.

Publication type:

Article

Stereoselective Synthesis of Highly Substituted Tetrahydrofurans through Diverted Carbene OH Insertion Reaction.

Published in:

Angewandte Chemie, 2015, v. 127, n. 29, p. 8605, doi. 10.1002/ange.201502484

By:

Nicolle, Simon M.;
Lewis, William;
Hayes, Christopher J.;
Moody, Christopher J.

Publication type:

Article

Chinone als Dienophile in der Diels‐Alder‐Reaktion – historische Entwicklung und Anwendungen in der Totalsynthese.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2086, doi. 10.1002/ange.201305908

By:

Nawrat, Christopher C.;
Moody, Christopher J.

Publication type:

Article

Chinone als Dienophile in der Diels-Alder-Reaktion - historische Entwicklung und Anwendungen in der Totalsynthese.

Published in:

Angewandte Chemie, 2014, v. 126, n. 8, p. 2086, doi. 10.1002/ange.201305908

By:

Nawrat, Christopher C.;
Moody, Christopher J.

Publication type:

Article

Reactivity Enhancement for Chiral Dirhodium(II) Tetrakis(Carboxamidates).

Published in:

Advanced Synthesis & Catalysis, 2001, v. 343, n. 1, p. 112, doi. 10.1002/1615-4169(20010129)343:1<112::AID-ADSC112>3.0.CO;2-M

By:

Doyle, Michael P.;
Hu, Wenhao;
Phillips, Iain M.;
Moody, Christopher J.;
Pepper, Adrian G.;
Slawin, Alexandra G. Z.

Publication type:

Article

Cytotoxic and Radiosensitising Effects of a Novel Thioredoxin Reductase Inhibitor in Brain Cancers.

Published in:

Molecular Neurobiology, 2022, v. 59, n. 6, p. 3546, doi. 10.1007/s12035-022-02808-4

By:

Yao, Anqi;
Storr, Sarah J.;
Inman, Martyn;
Barwell, Lucy;
Moody, Christopher J.;
Martin, Stewart G.

Publication type:

Article

Inhibition of Hsp90 with Resorcylic Acid Macrolactones: Synthesis and Binding Studies.

Published in:

Chemistry - A European Journal, 2010, v. 16, n. 34, p. 10366, doi. 10.1002/chem.201001119

By:

Day, James E. H.;
Sharp, Swee Y.;
Rowlands, Martin G.;
Aherne, Wynne;
Lewis, William;
Roe, S. Mark;
Prodromou, Chrisostomos;
Pearl, Laurence H.;
Workman, Paul;
Moody, Christopher J.

Publication type:

Article

Targeting the Hsp90 Chaperone: Synthesis of Novel Resorcylic Acid Macrolactone Inhibitors of Hsp90.

Published in:

Chemistry - A European Journal, 2010, v. 16, n. 9, p. 2758, doi. 10.1002/chem.200902766

By:

Day, James E. H.;
Sharp, Swee Y.;
Rowlands, Martin G.;
Aherne, Wynne;
Workman, Paul;
Moody, Christopher J.

Publication type:

Article

Total Synthesis of the Post-translationally Modified Polyazole Peptide Antibiotic Goadsporin.

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 11, p. 3069, doi. 10.1002/anie.201612103

By:

Dexter, Hannah L.;
Williams, Huw E. L.;
Lewis, William;
Moody, Christopher J.

Publication type:

Article

Stereoselective Synthesis of Functionalized Pyrrolidines by the Diverted N−H Insertion Reaction of Metallocarbenes with β-Aminoketone Derivatives.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 11, p. 3749, doi. 10.1002/anie.201511433

By:

Nicolle, Simon M.;
Lewis, William;
Hayes, Christopher J.;
Moody, Christopher J.

Publication type:

Article

Total Synthesis of the Posttranslationally Modified Polyazole Peptide Antibiotic Plantazolicin A.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 50, p. 15147, doi. 10.1002/anie.201507062

By:

Hiroki Wada;
Williams, Huw E. L.;
Moody, Christopher J.

Publication type:

Article

Synthesis and Intracellular Redox Cycling of Natural Quinones and Their Analogues and Identification of Indoleamine-2,3-dioxygenase (IDO) as Potential Target for Anticancer Activity.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 30, p. 8740, doi. 10.1002/anie.201503323

By:

Blunt, Christopher E.;
Torcuk, Canan;
Liu, Yang;
Lewis, William;
Siegel, David;
Ross, David;
Moody, Christopher J.

Publication type:

Article

Stereoselective Synthesis of Highly Substituted Tetrahydrofurans through Diverted Carbene OH Insertion Reaction.

Published in:

Angewandte Chemie International Edition, 2015, v. 54, n. 29, p. 8485, doi. 10.1002/anie.201502484

By:

Nicolle, Simon M.;
Lewis, William;
Hayes, Christopher J.;
Moody, Christopher J.

Publication type:

Article

Quinones as Dienophiles in the Diels-Alder Reaction: History and Applications in Total Synthesis.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 8, p. 2056, doi. 10.1002/anie.201305908

By:

Nawrat, Christopher C.;
Moody, Christopher J.

Publication type:

Article

Sexual selection predicts the rate and direction of colour divergence in a large avian radiation.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09859-7

By:

Cooney, Christopher R.;
Varley, Zoë K.;
Nouri, Lara O.;
Moody, Christopher J. A.;
Jardine, Michael D.;
Thomas, Gavin H.

Publication type:

Article