Works by Monkhorst, Kim

Results: 29

X chromosome choice occurs independently of asynchronous replication timing.

Published in:

Journal of Cell Biology, 2005, v. 168, n. 3, p. 365, doi. 10.1083/jcb.200405117

By:

Gribnau, Joost;
Luikenhuis, Sandra;
Hochedlinger, Konrad;
Monkhorst, Kim;
Jaenisch, Rudolf

Publication type:

Article

Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24537-3

By:

Prekovic, Stefan;
Schuurman, Karianne;
Mayayo-Peralta, Isabel;
Manjón, Anna G.;
Buijs, Mark;
Yavuz, Selçuk;
Wellenstein, Max D.;
Barrera, Alejandro;
Monkhorst, Kim;
Huber, Anne;
Morris, Ben;
Lieftink, Cor;
Chalkiadakis, Theofilos;
Alkan, Ferhat;
Silva, Joana;
Győrffy, Balázs;
Hoekman, Liesbeth;
van den Broek, Bram;
Teunissen, Hans;
Debets, Donna O.

Publication type:

Article

The Probability to Initiate X Chromosome Inactivation Is Determined by the X to Autosomal Ratio and X Chromosome Specific Allelic Properties.

Published in:

PLoS ONE, 2009, v. 4, n. 5, p. 1, doi. 10.1371/journal.pone.0005616

By:

Monkhorst, Kim;
de Hoon, Bas;
Jonkers, Iris;
Achame, Eskeatnaf Mulugeta;
Monkhorst, Wouter;
Hoogerbrugge, Jos;
Rentmeester, Eveline;
Westerhoff, Hans V.;
Grosveld, Frank;
Grootegoed, J. Anton;
Gribnau, Joost

Publication type:

Article

Study protocol: Whole genome sequencing Implementation in standard Diagnostics for Every cancer patient (WIDE).

Published in:

BMC Medical Genomics, 2020, v. 13, n. 1, p. N.PAG, doi. 10.1186/s12920-020-00814-w

By:

Samsom, Kris G.;
Bosch, Linda J. W.;
Schipper, Luuk J.;
Roepman, Paul;
de Bruijn, Ewart;
Hoes, Louisa R.;
Riethorst, Immy;
Schoenmaker, Lieke;
van der Kolk, Lizet E.;
Retèl, Valesca P.;
Frederix, Geert W. J.;
Buffart, Tineke E.;
van der Hoeven, Jacobus J. M.;
Voest, Emile E.;
Cuppen, Edwin;
Monkhorst, Kim;
Meijer, Gerrit A.

Publication type:

Article

Survival difference between patients with single versus multiple metastatic lymph nodes and the role of histology in pathological stage II-N1 non-small cell lung cancer.

Published in:

Acta Chirurgica Belgica, 2024, v. 124, n. 5, p. 387, doi. 10.1080/00015458.2024.2322243

By:

Ruiter, Julianne;
de Langen, Adrianus;
Monkhorst, Kim;
Veenhof, Alexander;
Klomp, Houke;
Smit, Jasper;
Smit, Egbert;
Damhuis, Ronald;
Hartemink, Koen

Publication type:

Article

Phase I study of lapatinib plus trametinib in patients with KRAS-mutant colorectal, non-small cell lung, and pancreatic cancer.

Published in:

2020

By:

Huijberts, Sanne C. F. A.;
van Geel, Robin M. J. M.;
van Brummelen, Emilie M. J.;
Opdam, Frans L.;
Marchetti, Serena;
Steeghs, Neeltje;
Pulleman, Saskia;
Thijssen, Bas;
Rosing, Hilde;
Monkhorst, Kim;
Huitema, Alwin D. R.;
Beijnen, Jos H.;
Bernards, René;
Schellens, Jan H. M.

Publication type:

journal article

Xist RNA Is Confined to the Nuclear Territory of the Silenced X Chromosome throughout the Cell Cycle.

Published in:

Molecular & Cellular Biology, 2008, v. 28, n. 18, p. 5583, doi. 10.1128/MCB.02269-07

By:

Jonkers, Iris;
Monkhorst, Kim;
Rentmeester, Eveline;
Grootegoed, J. Anton;
Grosveld, Frank;
Gribnau, Joost

Publication type:

Article

A review on genetic alterations in CNS metastases related to breast cancer treatment. Is there a role for liquid biopsies in CSF?

Published in:

Journal of Neuro-Oncology, 2023, v. 162, n. 1, p. 1, doi. 10.1007/s11060-023-04261-2

By:

Wessels, Peter H.;
Boelens, Mirjam C.;
Monkhorst, Kim;
Sonke, Gabe S.;
van den Broek, Daan;
Brandsma, Dieta

Publication type:

Article

Implementation of Novel Molecular Biomarkers for Non-small Cell Lung Cancer in the Netherlands: How to Deal With Increasing Complexity.

Published in:

Frontiers in Oncology, 2020, v. 9, p. 1, doi. 10.3389/fonc.2019.01521

By:

van den Broek, Daan;
Hiltermann, T. Jeroen N.;
Biesma, Bonne;
Dinjens, Winand N. M.;
't Hart, Nils A.;
Hinrichs, John W. J.;
Leers, Mathie P. G.;
Monkhorst, Kim;
van Oosterhout, Matthijs;
Scharnhorst, Volkher;
Schuuring, Ed;
Speel, Ernst-Jan M.;
van den Heuvel, Michel M.;
van Schaik, Ron H. N.;
von der Thüsen, Jan;
Willems, Stefan M.;
de Visser, Leonie;
Ligtenberg, Marjolijn J. L.

Publication type:

Article

Implementation of Novel Molecular Biomarkers for Non-small Cell Lung Cancer in the Netherlands: How to Deal With Increasing Complexity.

Published in:

Frontiers in Oncology, 2020, v. 10, p. 1, doi. 10.3389/fonc.2019.01521

By:

van den Broek, Daan;
Hiltermann, T. Jeroen N.;
Biesma, Bonne;
Dinjens, Winand N. M.;
't Hart, Nils A.;
Hinrichs, John W. J.;
Leers, Mathie P. G.;
Monkhorst, Kim;
van Oosterhout, Matthijs;
Scharnhorst, Volkher;
Schuuring, Ed;
Speel, Ernst-Jan M.;
van den Heuvel, Michel M.;
van Schaik, Ron H. N.;
von der Thüsen, Jan;
Willems, Stefan M.;
de Visser, Leonie;
Ligtenberg, Marjolijn J. L.

Publication type:

Article

Cell-Free DNA at Diagnosis for Stage IV Non-Small Cell Lung Cancer: Costs, Time to Diagnosis and Clinical Relevance.

Published in:

Cancers, 2022, v. 14, n. 7, p. 1783, doi. 10.3390/cancers14071783

By:

Koole, Simone N.;
Vessies, Daan C. L.;
Schuurbiers, Milou M. F.;
Kramer, Astrid;
Schouten, Robert D.;
Degeling, Koen;
Bosch, Linda J. W.;
van den Heuvel, Michel M.;
van Harten, Wim H.;
van den Broek, Daan;
Monkhorst, Kim;
Retèl, Valesca P.

Publication type:

Article

Clinical Impact of Prospective Whole Genome Sequencing in Sarcoma Patients.

Published in:

Cancers, 2022, v. 14, n. 2, p. 436, doi. 10.3390/cancers14020436

By:

Schipper, Luuk J.;
Monkhorst, Kim;
Samsom, Kris G.;
Bosch, Linda J.W.;
Snaebjornsson, Petur;
van Boven, Hester;
Roepman, Paul;
van der Kolk, Lizet E.;
van Houdt, Winan J.;
van der Graaf, Winette T.A.;
Meijer, Gerrit A.;
Voest, Emile E.

Publication type:

Article

Head-to-head comparison of composite and individual biomarkers to predict clinical benefit to PD-1 blockade in non-small cell lung cancer.

Published in:

PLoS ONE, 2024, v. 19, n. 7, p. 1, doi. 10.1371/journal.pone.0293707

By:

Hummelink, Karlijn;
van der Noort, Vincent;
Muller, Mirte;
Schouten, Robert D.;
van den Heuvel, Michel M.;
Thommen, Daniela S.;
Smit, Egbert F.;
Meijer, Gerrit A.;
Monkhorst, Kim

Publication type:

Article

Formalin fixation for optimal concordance of programmed death‐ligand 1 immunostaining between cytologic and histologic specimens from patients with non–small cell lung cancer.

Published in:

Cancer Cytopathology, 2021, v. 129, n. 4, p. 304, doi. 10.1002/cncy.22383

By:

Koomen, Bregje M.;
Starre‐Gaal, Jose;
Vonk, Judith M.;
Thüsen, Jan H.;
Meij, Jacqueline J. C.;
Monkhorst, Kim;
Willems, Stefan M.;
Timens, Wim;
't Hart, Nils A.

Publication type:

Article

A phase 2 trial combining afatinib with cetuximab in patients with EGFR exon 20 insertion–positive non–small cell lung cancer.

Published in:

Cancer (0008543X), 2024, v. 130, n. 5, p. 683, doi. 10.1002/cncr.35090

By:

van Veggel, Bianca A. M. H.;
van der Wekken, Anthonie J.;
Paats, Marthe S.;
Hendriks, Lizza E. L.;
Hashemi, Sayed M. S.;
Daletzakis, Antonios;
van den Broek, Daan;
Bosch, Linda J. W.;
Monkhorst, Kim;
Smit, Egbert F.;
de Langen, Adrianus J.

Publication type:

Article

Multicenter Comparison of Molecular Tumor Boards in The Netherlands: Definition, Composition, Methods, and Targeted Therapy Recommendations.

Published in:

Oncologist, 2021, v. 26, n. 8, p. e1347, doi. 10.1002/onco.13580

By:

Koopman, Bart;
Groen, Harry J.M.;
Ligtenberg, Marjolijn J.L.;
Grünberg, Katrien;
Monkhorst, Kim;
de Langen, Adrianus J.;
Boelens, Mirjam C.;
Paats, Marthe S.;
von der Thüsen, Jan H.;
Dinjens, Winand N.M.;
Solleveld, Nienke;
van Wezel, Tom;
Gelderblom, Hans;
Hendriks, Lizza E.;
Speel, Ernst‐Jan M.;
Theunissen, Tom E.;
Kroeze, Leonie I.;
Mehra, Niven;
Piet, Berber;
van der Wekken, Anthonie J.

Publication type:

Article

Phase I Study of Afatinib and Selumetinib in Patients with KRAS‐Mutated Colorectal, Non‐Small Cell Lung, and Pancreatic Cancer.

Published in:

Oncologist, 2021, v. 26, n. 4, p. 290, doi. 10.1002/onco.13631

By:

Brummelen, Emilie M.J.;
Huijberts, Sanne;
Herpen, Carla;
Desar, Ingrid;
Opdam, Frans;
Geel, Robin;
Marchetti, Serena;
Steeghs, Neeltje;
Monkhorst, Kim;
Thijssen, Bas;
Rosing, Hilde;
Huitema, Alwin;
Beijnen, Jos;
Bernards, Rene;
Schellens, Jan

Publication type:

Article

Blastic plasmacytoid dendritic cell neoplasm.

Published in:

British Journal of Haematology, 2014, v. 164, n. 6, p. 757, doi. 10.1111/bjh.12666

By:

Roodbergen, Sofie L.;
Hofland, Johannes;
Lam, King H.;
Dikrama, Petra K.;
Broyl, Annemiek;
Monkhorst, Kim

Publication type:

Article

An Automated Correction Algorithm (ALPACA) for ddPCR Data Using Adaptive Limit of Blank and Correction of False Positive Events Improves Specificity of Mutation Detection.

Published in:

Clinical Chemistry, 2021, v. 67, n. 7, p. 959, doi. 10.1093/clinchem/hvab040

By:

Vessies, Daan C. L.;
Linders, Theodora C.;
Lanfermeijer, Mirthe;
Ramkisoensing, Kalpana L.;
van der Noort, Vincent;
Schouten, Robert D.;
Meijer, Gerrit A.;
van den Heuvel, Michel M.;
Monkhorst, Kim;
den Broek, Daan van

Publication type:

Article

Recurrence prediction using circulating tumor DNA in patients with early-stage non-small cell lung cancer after treatment with curative intent: A retrospective validation study.

Published in:

PLoS Medicine, 2025, v. 22, n. 4, p. 1, doi. 10.1371/journal.pmed.1004574

By:

Schuurbiers, Milou M. F.;
Smith, Christopher G.;
Hartemink, Koen J.;
Rintoul, Robert C.;
Gale, Davina;
Monkhorst, Kim;
Mandos, Bas L. R.;
Paterson, Anna L.;
van den Broek, Dan;
Rosenfeld, Nitzan;
van den Heuvel, Michel M.

Publication type:

Article

Importance of tumour volume and histology in trimodality treatment of patients with Stage IIIA non-small cell lung cancer—results from a retrospective analysis.

Published in:

Interactive Cardiovascular & Thoracic Surgery, 2022, v. 34, n. 4, p. 566, doi. 10.1093/icvts/ivab291

By:

Joosten, Pieter J M;
Dickhoff, Chris;
van der Noort, Vincent;
Smeekens, Maarten;
Numan, Rachel C;
Klomp, Houke M;
Diessen, Judi N A van;
Belderbos, Jose S A;
Smit, Egbert F;
Monkhorst, Kim;
Oosterhuis, Jan W A;
Heuvel, Michel M van den;
Dahele, Max;
Hartemink, Koen J

Publication type:

Article

Absence of PD-L1 expression on tumor cells in the context of an activated immune infiltrate may indicate impaired IFNγ signaling in non-small cell lung cancer.

Published in:

PLoS ONE, 2019, v. 14, n. 5, p. 1, doi. 10.1371/journal.pone.0216864

By:

Theelen, Willemijn S. M. E.;
Kuilman, Thomas;
Schulze, Katja;
Zou, Wei;
Krijgsman, Oscar;
Peters, Dennis D. G. C.;
Cornelissen, Sten;
Monkhorst, Kim;
Sarma, Pranamee;
Sumiyoshi, Teiko;
Amler, Lukas C.;
Willems, Stefan M.;
Blaauwgeers, Johannes L. G.;
van Noesel, Carel J. M.;
Peeper, Daniel S.;
van den Heuvel, Michel M.;
Kowanetz, Marcin

Publication type:

Article

Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer.

Published in:

2020

By:

van Geel, Robin M. J. M.;
van Brummelen, Emilie M. J.;
Eskens, Ferry A. L. M.;
Huijberts, Sanne C. F. A.;
de Vos, Filip Y. F. L.;
Lolkema, Martijn P. J. K.;
Devriese, Lot A.;
Opdam, Frans L.;
Marchetti, Serena;
Steeghs, Neeltje;
Monkhorst, Kim;
Thijssen, Bas;
Rosing, Hilde;
Huitema, Alwin D. R.;
Beijnen, Jos H.;
Bernards, René;
Schellens, Jan H. M.

Publication type:

journal article

Trastuzumab and paclitaxel in patients with EGFR mutated NSCLC that express HER2 after progression on EGFR TKI treatment.

Published in:

British Journal of Cancer, 2018, v. 119, n. 5, p. 558, doi. 10.1038/s41416-018-0194-7

By:

de Langen, Adrianus J.;
Jebbink, M.;
Hashemi, Sayed M. S.;
Kuiper, Justine L.;
de Bruin-Visser, J.;
Monkhorst, Kim;
Thunnissen, Erik;
Smit, Egbert F.

Publication type:

Article

Trastuzumab and paclitaxel in patients with EGFR mutated NSCLC that express HER2 after progression on EGFR TKI treatment.

Published in:

2018

By:

de Langen, Adrianus J;
Jebbink, M;
Hashemi, Sayed M S;
Kuiper, Justine L;
de Bruin-Visser, J;
Monkhorst, Kim;
Thunnissen, Erik;
Smit, Egbert F

Publication type:

journal article

Osimertinib-induced DNA resistance mutations in cerebrospinal fluid of epidermal growth factor receptor-mutated non-small-cell lung carcinoma patients developing leptomeningeal metastases: Osimertinib Resistance Analysis-leptomeningeal metastases study.

Published in:

Neuro-Oncology, 2024, v. 26, n. 12, p. 2316, doi. 10.1093/neuonc/noae138

By:

Wel, J W Tijmen van der;
Boelens, Mirjam C;
Jebbink, Merel;
Smulders, Sietske A;
Maas, Klaartje W;
Luitse, Merel J A;
Compter, Annette;
Boltjes, Robin P B;
Sol, Nik;
Monkhorst, Kim;
van den Broek, Daan;
Smit, Egbert F;
Langen, Adrianus J de;
Brandsma, Dieta

Publication type:

Article

Identification of protein biomarkers for prediction of response to platinum‐based treatment regimens in patients with non‐small cell lung cancer.

Published in:

Molecular Oncology, 2024, v. 18, n. 6, p. 1417, doi. 10.1002/1878-0261.13555

By:

Böttger, Franziska;
Radonic, Teodora;
Bahce, Idris;
Monkhorst, Kim;
Piersma, Sander R.;
Pham, Thang V.;
Dingemans, Anne‐Marie C.;
Hillen, Lisa M.;
Santarpia, Mariacarmela;
Giovannetti, Elisa;
Smit, Egbert F.;
Burgers, Sjaak A.;
Jimenez, Connie R.

Publication type:

Article

Combining variant detection and fragment length analysis improves detection of minimal residual disease in postsurgery circulating tumour DNA of stage II-IIIA NSCLC patients.

Published in:

Molecular Oncology, 2022, v. 16, n. 14, p. 2719, doi. 10.1002/1878-0261.13267

By:

Vessies, Daan C. L.;
Schuurbiers, Milou M. F.;
van der Noort, Vincent;
Schouten, Irene;
Linders, Theodora C.;
Lanfermeijer, Mirthe;
Ramkisoensing, Kalpana L.;
Hartemink, Koen J.;
Monkhorst, Kim;
van den Heuvel, Michel M.;
van den Broek, Daan

Publication type:

Article

Generation and characterization of an inducible transgenic model for studying mouse esophageal biology.

Published in:

BMC Developmental Biology, 2012, v. 12, n. 1, p. 18, doi. 10.1186/1471-213X-12-18

By:

Roth, Sabrina;
Franken, Patrick;
Monkhorst, Kim;
Kong a San, John;
Fodde, Riccardo

Publication type:

Article