Works by Mohlke, Karen L.

Results: 73

Mediation analysis of multiple mediators with incomplete omics data.

Published in:

Genetic Epidemiology, 2023, v. 47, n. 1, p. 61, doi. 10.1002/gepi.22504

By:

Kidd, John;
Raulerson, Chelsea K.;
Mohlke, Karen L.;
Lin, Dan‐Yu

Publication type:

Article

Assessing exposure effects on gene expression.

Published in:

Genetic Epidemiology, 2020, v. 44, n. 6, p. 601, doi. 10.1002/gepi.22324

By:

Reifeis, Sarah A.;
Hudgens, Michael G.;
Civelek, Mete;
Mohlke, Karen L.;
Love, Michael I.

Publication type:

Article

Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database.

Published in:

Genetic Epidemiology, 2006, v. 30, n. 2, p. 180, doi. 10.1002/gepi.20131

By:

Cristen J. Willer;
Laura J. Scott;
Lori L. Bonnycastle;
Anne U. Jackson;
Peter Chines;
Randall Pruim;
Craig W. Bark;
Ya‐Yu Tsai;
Elizabeth W. Pugh;
Kimberly F. Doheny;
Leena Kinnunen;
Karen L. Mohlke;
Timo T. Valle;
Richard N. Bergman;
Jaakko Tuomilehto;
Francis S. Collins;
Michael Boehnke

Publication type:

Article

Inferring Regulatory Networks From Mixed Observational Data Using Directed Acyclic Graphs.

Published in:

Frontiers in Genetics, 2020, p. 1, doi. 10.3389/fgene.2020.00008

By:

Zhong, Wujuan;
Dong, Li;
Poston, Taylor B.;
Darville, Toni;
Spracklen, Cassandra N.;
Wu, Di;
Mohlke, Karen L.;
Li, Yun;
Li, Quefeng;
Zheng, Xiaojing

Publication type:

Article

A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex‐Biased Phenotypes.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 6, p. 1383, doi. 10.1002/cpt.1751

By:

Etheridge, Amy S.;
Gallins, Paul J.;
Jima, Dereje;
Broadaway, K. Alaine;
Ratain, Mark J.;
Schuetz, Erin;
Schadt, Eric;
Schroder, Adrian;
Molony, Cliona;
Zhou, Yihui;
Mohlke, Karen L.;
Wright, Fred A.;
Innocenti, Federico

Publication type:

Article

Single-nucleotide polymorphisms at five loci are associated with C-reactive protein levels in a cohort of Filipino young adults.

Published in:

Journal of Human Genetics, 2011, v. 56, n. 12, p. 823, doi. 10.1038/jhg.2011.106

By:

Curocichin, Ghenadie;
Wu, Ying;
McDade, Thomas W;
Kuzawa, Christopher W;
Borja, Judith B;
Qin, Li;
Lange, Ethan M;
Adair, Linda S;
Lange, Leslie A;
Mohlke, Karen L

Publication type:

Article

Comparison of ENCODE region SNPs between Cebu Filipino and Asian HapMap samples.

Published in:

Journal of Human Genetics, 2007, v. 52, n. 9, p. 729, doi. 10.1007/s10038-007-0175-9

By:

Marvelle, Amanda F.;
Lange, Leslie A.;
Li Qin;
Yunfei Wang;
Lange, Ethan M.;
Adair, Linda S.;
Mohlke, Karen L.

Publication type:

Article

Exome sequencing reveals novel variants and unique allelic spectrum for hearing impairment in Filipino cochlear implantees.

Published in:

Clinical Genetics, 2019, v. 95, n. 5, p. 634, doi. 10.1111/cge.13515

By:

Truong, Brittany T.;
Yarza, Talitha K.L.;
Bootpetch Roberts, Tori;
Roberts, Susannah;
Xu, Jonathan;
Steritz, Matthew J.;
Tobias‐Grasso, Celina A.M.;
Azamian, Mahshid;
Lalani, Seema R.;
Mohlke, Karen L.;
Lee, Nanette R.;
Cutiongco‐de la Paz, Eva Maria;
Reyes‐Quintos, Maria Rina T.;
Santos‐Cortez, Regie Lyn P.;
Chiong, Charlotte M.

Publication type:

Article

Evidence for Association between SH2B1 Gene Variants and Glycated Hemoglobin in Nondiabetic European American Young Adults: The Add Health Study.

Published in:

Annals of Human Genetics, 2016, v. 80, n. 5, p. 294, doi. 10.1111/ahg.12165

By:

Lange, Leslie A.;
Graff, Mariaelisa;
Lange, Ethan M.;
Young, Kristin L.;
Richardson, Andrea S.;
Mohlke, Karen L.;
North, Kari E;
Harris, Kathleen M;
Gordon‐Larsen, Penny

Publication type:

Article

A map of open chromatin in human pancreatic islets.

Published in:

Nature Genetics, 2010, v. 42, n. 3, p. 255, doi. 10.1038/ng.530

By:

Gaulton, Kyle J.;
Nammo, Takao;
Pasquali, Lorenzo;
Simon, Jeremy M.;
Giresi, Paul G.;
Fogarty, Marie P.;
Panhuis, Tami M.;
Mieczkowski, Piotr;
Secchi, Antonio;
Bosco, Domenico;
Berney, Thierry;
Montanya, Eduard;
Mohlke, Karen L.;
Lieb, Jason D.;
Ferrer, Jorge

Publication type:

Article

Nonsynonymous variants and fatty liver disease.

Published in:

Nature Genetics, 2008, v. 40, n. 12, p. 1394, doi. 10.1038/ng1208-1394

By:

Mohlke, Karen L.

Publication type:

Article

Identification of a Regulatory Variant That Binds FOXA1 and FOXA2 at the CDC123/CAMK1D Type 2 Diabetes GWAS Locus.

Published in:

PLoS Genetics, 2014, v. 10, n. 9, p. 1, doi. 10.1371/journal.pgen.1004633

By:

Fogarty, Marie P.;
Cannon, Maren E.;
Vadlamudi, Swarooparani;
Gaulton, Kyle J.;
Mohlke, Karen L.

Publication type:

Article

Fine-Mapping and Initial Characterization of QT Interval Loci in African Americans.

Published in:

PLoS Genetics, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.pgen.1002870

By:

Avery, Christy L.;
Sethupathy, Praveen;
Buyske, Steven;
He, Qianchuan;
Lin, Dan-Yu;
Arking, Dan E.;
Carty, Cara L.;
Duggan, David;
Fesinmeyer, Megan D.;
Hindorff, Lucia A.;
Jeff, Janina M.;
Klein, Liviu;
Patton, Kristen K.;
Peters, Ulrike;
Shohet, Ralph V.;
Sotoodehnia, Nona;
Young, Alicia M.;
Kooperberg, Charles;
Haiman, Christopher A.;
Mohlke, Karen L.

Publication type:

Article

A computational system to select candidate genes for complex human traits.

Published in:

Bioinformatics, 2007, v. 23, n. 9, p. 1132, doi. 10.1093/bioinformatics/btm001

By:

Kyle J. Gaulton;
Karen L. Mohlke;
Todd J. Vision

Publication type:

Article

Genome-Wide Association Study of Anthropometric Traits and Evidence of Interactions With Age and Study Year in Filipino Women.

Published in:

Obesity (19307381), 2011, v. 19, n. 5, p. 1019, doi. 10.1038/oby.2010.256

By:

Croteau-Chonka, Damien C.;
Marvelle, Amanda F.;
Lange, Ethan M.;
Lee, Nanette R.;
Adair, Linda S.;
Lange, Leslie A.;
Mohlke, Karen L.

Publication type:

Article

Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease.

Published in:

2019

By:

Qiong Jia;
Yi Han;
Pin Huang;
Woodward, Nicholas C.;
Gukasyan, Janet;
Kettunen, Johannes;
Ala-Korpela, Mika;
Anufrieva, Olga;
Qin Wang;
Perola, Markus;
Raitakari, Olli;
Lehtimäki, Terho;
Viikari, Jorma;
Järvelin, Marjo-Riitta;
Boehnke, Michael;
Laakso, Markku;
Mohlke, Karen L.;
Fiehn, Oliver;
Zeneng Wang;
Tang, W. H. Wilson

Publication type:

journal article

Associations of genetic variants in/near body mass index-associated genes with type 2 diabetes: a systematic meta-analysis.

Published in:

Clinical Endocrinology, 2014, v. 81, n. 5, p. 702, doi. 10.1111/cen.12428

By:

Xi, Bo;
Takeuchi, Fumihiko;
Meirhaeghe, Aline;
Kato, Norihiro;
Chambers, John C.;
Morris, Andrew P.;
Cho, Yoon Shin;
Zhang, Weihua;
Mohlke, Karen L.;
Kooner, Jaspal S.;
Shu, Xiao Ou;
Pan, Hongwei;
Tai, E Shyong;
Pan, Haiyan;
Wu, Jer‐Yuarn;
Zhou, Donghao;
Chandak, Giriraj R.

Publication type:

Article

Alterations to chromatin in intestinal macrophages link IL-10 deficiency to inappropriate inflammatory responses.

Published in:

European Journal of Immunology, 2016, v. 46, n. 8, p. 1912, doi. 10.1002/eji.201546237

By:

Simon, Jeremy M.;
Davis, James P.;
Lee, Saangyoung E.;
Schaner, Matthew R.;
Gipson, Gregory R.;
Weiser, Matthew;
Sartor, R. Balfour;
Herfarth, Hans H.;
Rahbar, Reza;
Sadiq, Timothy S.;
Koruda, Mark J.;
McGovern, Dermot P.;
Lieb, Jason D.;
Mohlke, Karen L.;
Furey, Terrence S.;
Sheikh, Shehzad Z.

Publication type:

Article

Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits.

Published in:

G3: Genes | Genomes | Genetics, 2019, v. 9, n. 8, p. 2521, doi. 10.1534/g3.119.400294

By:

Cannon, Maren E.;
Currin, Kevin W.;
Young, Kristin L.;
Perrin, Hannah J.;
Vadlamudi, Swarooparani;
Safi, Alexias;
Lingyun Song;
Ying Wu;
Wabitsch, Martin;
Laakso, Markku;
Crawford, Gregory E.;
Mohlke, Karen L.

Publication type:

Article

Trans-ancestry Fine Mapping and Molecular Assays Identify Regulatory Variants at the ANGPTL8 HDL-C GWAS Locus.

Published in:

G3: Genes | Genomes | Genetics, 2017, v. 7, n. 9, p. 3217, doi. 10.1534/g3.117.300088

By:

Cannon, Maren E.;
Qing Duan;
Ying Wu;
Zeynalzadeh, Monica;
Zheng Xu;
Kangas, Antti J.;
Soininen, Pasi;
Ala-Korpela, Mika;
Civelek, Mete;
Lusis, Aldons J.;
Kuusisto, Johanna;
Collins, Francis S.;
Boehnke, Michael;
Hua Tang;
Laakso, Markku;
Yun Li;
Mohlke, Karen L.

Publication type:

Article

Identification of Novel Candidate Genes and Variants for Hearing Loss and Temporal Bone Anomalies.

Published in:

Genes, 2021, v. 12, n. 4, p. 566, doi. 10.3390/genes12040566

By:

Santos-Cortez, Regie Lyn P.;
Yarza, Talitha Karisse L.;
Bootpetch, Tori C.;
Tantoco, Ma. Leah C.;
Mohlke, Karen L.;
Cruz, Teresa Luisa G.;
Chiong Perez, Mary Ellen;
Chan, Abner L.;
Lee, Nanette R.;
Tobias-Grasso, Celina Ann M.;
Reyes-Quintos, Maria Rina T.;
Cutiongco-de la Paz, Eva Maria;
Chiong, Charlotte M.

Publication type:

Article

Author Correction: Identification of genetic effects underlying type 2 diabetes in South Asian and European populations.

Published in:

2022

By:

Loh, Marie;
Zhang, Weihua;
Ng, Hong Kiat;
Schmid, Katharina;
Lamri, Amel;
Tong, Lin;
Ahmad, Meraj;
Lee, Jung-Jin;
Ng, Maggie C. Y.;
Petty, Lauren E.;
Spracklen, Cassandra N.;
Takeuchi, Fumihiko;
Islam, Md. Tariqul;
Jasmine, Farzana;
Kasturiratne, Anuradhani;
Kibriya, Muhammad;
Mohlke, Karen L.;
Paré, Guillaume;
Prasad, Gauri;
Shahriar, Mohammad

Publication type:

Correction Notice

Identification of genetic effects underlying type 2 diabetes in South Asian and European populations.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03248-5

By:

Loh, Marie;
Zhang, Weihua;
Ng, Hong Kiat;
Schmid, Katharina;
Lamri, Amel;
Tong, Lin;
Ahmad, Meraj;
Lee, Jung-Jin;
Ng, Maggie C. Y.;
Petty, Lauren E.;
Spracklen, Cassandra N.;
Takeuchi, Fumihiko;
Islam, Md. Tariqul;
Jasmine, Farzana;
Kasturiratne, Anuradhani;
Kibriya, Muhammad;
Mohlke, Karen L.;
Paré, Guillaume;
Prasad, Gauri;
Shahriar, Mohammad

Publication type:

Article

Identification of genetic effects underlying type 2 diabetes in South Asian and European populations.

Published in:

Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03248-5

By:

Loh, Marie;
Zhang, Weihua;
Ng, Hong Kiat;
Schmid, Katharina;
Lamri, Amel;
Tong, Lin;
Ahmad, Meraj;
Lee, Jung-Jin;
Ng, Maggie C. Y.;
Petty, Lauren E.;
Spracklen, Cassandra N.;
Takeuchi, Fumihiko;
Islam, Md. Tariqul;
Jasmine, Farzana;
Kasturiratne, Anuradhani;
Kibriya, Muhammad;
Mohlke, Karen L.;
Paré, Guillaume;
Prasad, Gauri;
Shahriar, Mohammad

Publication type:

Article

Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.

Published in:

Human Molecular Genetics, 2008, v. 17, n. R2, p. R102, doi. 10.1093/hmg/ddn275

By:

Mohlke, Karen L.;
Boehnke, Michael;
Abecasis, Gonçalo R.

Publication type:

Article

Age-dependent genes in adipose stem and precursor cells affect regulation of fat cell differentiation and link aging to obesity via cellular and genetic interactions.

Published in:

Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01291-x

By:

Kar, Asha;
Alvarez, Marcus;
Garske, Kristina M.;
Huang, Huiling;
Lee, Seung Hyuk T.;
Deal, Milena;
Das, Sankha Subhra;
Koka, Amogha;
Jamal, Zoeb;
Mohlke, Karen L.;
Laakso, Markku;
Heinonen, Sini;
Pietiläinen, Kirsi H.;
Pajukanta, Päivi

Publication type:

Article

A common frameshift mutation in von Willebrand factor does not alter mRNA stability but interferes with normal propeptide processing.

Published in:

British Journal of Haematology, 1996, v. 95, n. 1, p. 184, doi. 10.1046/j.1365-2141.1996.7572377.x

By:

Mohlke, Karen L.;
Nichols, William C.;
Rehemtulla, Alnawaz;
Kaufman, Randal J.;
Fagerström, Heidi M.;
Ritvanen, K. L. Annukka;
Kekomäki, Riitta;
Ginsburg, David

Publication type:

Article

Interaction of smoking and obesity susceptibility loci on adolescent BMI: The National Longitudinal Study of Adolescent to Adult Health.

Published in:

BMC Genetics, 2015, v. 16, p. 1, doi. 10.1186/s12863-015-0289-6

By:

Young, Kristin L.;
Graff, Misa;
North, Kari E.;
Richardson, Andrea S.;
Mohlke, Karen L.;
Lange, Leslie A.;
Lange, Ethan M.;
Harris, Kathleen M.;
Gordon-Larsen, Penny

Publication type:

Article

Multi-SNP mediation intersection-union test.

Published in:

Bioinformatics, 2019, v. 35, n. 22, p. 4724, doi. 10.1093/bioinformatics/btz285

By:

Zhong, Wujuan;
Spracklen, Cassandra N;
Mohlke, Karen L;
Zheng, Xiaojing;
Fine, Jason;
Li, Yun

Publication type:

Article

HUGIn: Hi-C Unifying Genomic Interrogator.

Published in:

Bioinformatics, 2017, v. 33, n. 23, p. 3793, doi. 10.1093/bioinformatics/btx359

By:

Martin, Joshua S.;
Zheng Xu;
Reiner, Alex P.;
Mohlke, Karen L.;
Sullivan, Patrick;
Bing Ren;
Ming Hu;
Yun Li

Publication type:

Article

GREGOR: evaluating global enrichment of trait-associated variants in epigenomic features using a systematic, data-driven approach.

Published in:

2015

By:

Schmidt, Ellen M.;
Ji Zhang;
Wei Zhou;
Jin Chen;
Mohlke, Karen L.;
Chen, Y. Eugene;
Willer, Cristen J.

Publication type:

Product Review

A comprehensive SNP and indel imputability database.

Published in:

Bioinformatics, 2013, v. 29, n. 4, p. 528, doi. 10.1093/bioinformatics/bts724

By:

Duan, Qing;
Liu, Eric Yi;
Croteau-Chonka, Damien C.;
Mohlke, Karen L.;
Li, Yun

Publication type:

Article

Publisher Correction: Pla2g12b drives expansion of triglyceride-rich lipoproteins.

Published in:

2024

By:

Thierer, James H.;
Foresti, Ombretta;
Yadav, Pradeep Kumar;
Wilson, Meredith H.;
Moll, Tabea O. C.;
Shen, Meng-Chieh;
Busch-Nentwich, Elisabeth M.;
Morash, Margaret;
Mohlke, Karen L.;
Rawls, John F.;
Malhotra, Vivek;
Hussain, M. Mahmood;
Farber, Steven A.

Publication type:

Correction Notice

Pla2g12b drives expansion of triglyceride-rich lipoproteins.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46102-4

By:

Thierer, James H.;
Foresti, Ombretta;
Yadav, Pradeep Kumar;
Wilson, Meredith H.;
Moll, Tabea O. C.;
Shen, Meng-Chieh;
Busch-Nentwich, Elisabeth M.;
Morash, Margaret;
Mohlke, Karen L.;
Rawls, John F.;
Malhotra, Vivek;
Hussain, M. Mahmood;
Farber, Steven A.

Publication type:

Article

TBC1D30 regulates proinsulin and insulin secretion and is the target of a genomic association signal for proinsulin.

Published in:

Diabetologia, 2025, v. 68, n. 6, p. 1169, doi. 10.1007/s00125-025-06391-w

By:

Parsons, Victoria A.;
Vadlamudi, Swarooparani;
Voos, Kayleigh M.;
Rohy, Abigail E.;
Moxley, Anne H.;
Cannon, Maren E.;
Rosen, Jonathan D.;
Mills, Christine A.;
Herring, Laura E.;
Broadaway, K. Alaine;
Lorenzo, Damaris N.;
Mohlke, Karen L.

Publication type:

Article

Correction to: Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes.

Published in:

2021

By:

Pan, David Z.;
Miao, Zong;
Comenho, Caroline;
Rajkumar, Sandhya;
Koka, Amogha;
Lee, Seung Hyuk T.;
Alvarez, Marcus;
Kaminska, Dorota;
Ko, Arthur;
Sinsheimer, Janet S.;
Mohlke, Karen L.;
Mancuso, Nicholas;
Muñoz-Hernandez, Linda Liliana;
Herrera-Hernandez, Miguel;
Tusié-Luna, Maria Teresa;
Aguilar-Salinas, Carlos;
Pietiläinen, Kirsi H.;
Pihlajamäki, Jussi;
Laakso, Markku;
Garske, Kristina M.

Publication type:

Correction Notice

Identification of TBX15 as an adipose master trans regulator of abdominal obesity genes.

Published in:

Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00939-2

By:

Pan, David Z.;
Miao, Zong;
Comenho, Caroline;
Rajkumar, Sandhya;
Koka, Amogha;
Lee, Seung Hyuk T.;
Alvarez, Marcus;
Kaminska, Dorota;
Ko, Arthur;
Sinsheimer, Janet S.;
Mohlke, Karen L.;
Mancuso, Nicholas;
Muñoz-Hernandez, Linda Liliana;
Herrera-Hernandez, Miguel;
Tusié-Luna, Maria Teresa;
Aguilar-Salinas, Carlos;
Pietiläinen, Kirsi H.;
Pihlajamäki, Jussi;
Laakso, Markku;
Garske, Kristina M.

Publication type:

Article

Integration of DNA sequencing with population pharmacokinetics to improve the prediction of irinotecan exposure in cancer patients.

Published in:

2022

By:

Karas, Spinel;
Etheridge, Amy S.;
Nickerson, Deborah A.;
Cox, Nancy J.;
Mohlke, Karen L.;
Cecchin, Erika;
Toffoli, Giuseppe;
Mathijssen, Ron H. J.;
Forrest, Alan;
Bies, Robert R.;
Innocenti, Federico

Publication type:

journal article

Chromatin accessibility and gene expression during adipocyte differentiation identify context-dependent effects at cardiometabolic GWAS loci.

Published in:

PLoS Genetics, 2021, v. 17, n. 10, p. 1, doi. 10.1371/journal.pgen.1009865

By:

Perrin, Hannah J.;
Currin, Kevin W.;
Vadlamudi, Swarooparani;
Pandey, Gautam K.;
Ng, Kenneth K.;
Wabitsch, Martin;
Laakso, Markku;
Love, Michael I.;
Mohlke, Karen L.

Publication type:

Article

Mitochondrial polymorphisms and susceptibility to type 2 diabetes-related traits in Finns.

Published in:

Human Genetics, 2005, v. 118, n. 2, p. 245, doi. 10.1007/s00439-005-0046-4

By:

Mohlke, Karen L.;
Jackson, Anne U.;
Scott, Laura J.;
Peck, Erin C.;
Suh, Yong D.;
Chines, Peter S.;
Watanabe, Richard M.;
Buchanan, Thomas A.;
Conneely, Karen N.;
Erdos, Michael R.;
Narisu, Narisu;
Enloe, Sareena;
Valle, Timo T.;
Tuomilehto, Jaakko;
Bergman, Richard N.;
Boehnke, Michael;
Collins, Francis S.

Publication type:

Article

Author Correction: Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS.

Published in:

Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-05849-3

By:

Pan, David Z.;
Garske, Kristina M.;
Alvarez, Marcus;
Bhagat, Yash V.;
Boocock, James;
Nikkola, Elina;
Zong Miao;
Raulerson, Chelsea K.;
Cantor, Rita M.;
Civelek, Mete;
Glastonbury, Craig A.;
Small, Kerrin S.;
Boehnke, Michael;
Lusis, Aldons J.;
Sinsheimer, Janet S.;
Mohlke, Karen L.;
Laakso, Markku;
Pajukanta, Päivi;
Ko, Arthur

Publication type:

Article

Integration of human adipocyte chromosomal interactions with adipose gene expression prioritizes obesity-related genes from GWAS.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03554-9

By:

Pan, David Z.;
Garske, Kristina M.;
Alvarez, Marcus;
Bhagat, Yash V.;
Boocock, James;
Nikkola, Elina;
Zong Miao;
Raulerson, Chelsea K.;
Cantor, Rita M.;
Civelek, Mete;
Glastonbury, Craig A.;
Small, Kerrin S.;
Boehnke, Michael;
Lusis, Aldons J.;
Sinsheimer, Janet S.;
Mohlke, Karen L.;
Laakso, Markku;
Pajukanta, Päivi;
Ko, Arthur

Publication type:

Article

The interaction between physical activity and obesity gene variants in association with BMI: Does the obesogenic environment matter?

Published in:

FASEB Journal, 2013, v. 27, p. 236.5, doi. 10.1096/fasebj.27.1_supplement.236.5

By:

Richardson, Andrea S;
North, Kari E;
Graff, Mariaelisa;
Young, Kristin L;
Mohlke, Karen L;
Lange, Ethan M;
Lange, Leslie A;
Harris, Kathleen M;
Gordon‐Larsen, Penny

Publication type:

Article

A Partial Loss-of-Function Variant in Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emission Tomography Study.

Published in:

2018

By:

Latva-Rasku, Aino;
Honka, Miikka-Juhani;
Stancáková, Alena;
Koistinen, Heikki A.;
Kuusisto, Johanna;
Li Guan;
Manning, Alisa K.;
Stringham, Heather;
Gloyn, Anna L.;
Lindgren, Cecilia M.;
Collins, Francis S.;
Mohlke, Karen L.;
Scott, Laura J.;
Karjalainen, Tomi;
Nummenmaa, Lauri;
Boehnke, Michael;
Nuutila, Pirjo;
Laakso, Markku;
Stančáková, Alena;
Guan, Li

Publication type:

journal article

Association of Ketone Body Levels With Hyperglycemia and Type 2 Diabetes in 9,398 Finnish Men.

Published in:

Diabetes, 2013, v. 62, n. 10, p. 3618, doi. 10.2337/db12-1363

By:

Mahendran, Yuvaraj;
Vangipurapu, Jagadish;
Cederberg, Henna;
Stancáková, Alena;
Pihlajamäki, Jussi;
Soininen, Pasi;
Kangas, Antti J.;
Paananen, Jussi;
Civelek, Mete;
Saleem, Niyas K.;
Pajukanta, Päivi;
Lusis, Aldons J.;
Bonnycastle, Lori L.;
Morken, Mario A.;
Collins, Francis S.;
Mohlke, Karen L.;
Boehnke, Michael;
Ala-Korpela, Mika;
Kuusisto, Johanna;
Laakso, Markku

Publication type:

Article

Allele-Specific Transcriptional Activity at Type 2 Diabetes-Associated Single Nucleotide Polymorphisms in Regions of Pancreatic Islet Open Chromatin at the JAZF1 Locus.

Published in:

Diabetes, 2013, v. 62, n. 5, p. 1756, doi. 10.2337/db12-0972

By:

Fogarty, Marie P.;
Panhuis, Tami M.;
Vadlamudi, Swarooparani;
Buchkovich, Martin L.;
Mohlke, Karen L.

Publication type:

Article

Association of FTO With Obesity-Related Traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort.

Published in:

Diabetes, 2008, v. 57, n. 7, p. 1987, doi. 10.2337/db07-1700

By:

Marvelle, Amanda F.;
Lange, Leslie A.;
Qin, Li;
Mohlke, Karen L.;
Adair, Linda S.

Publication type:

Article

Association of Transcription Factor 7-Like 2 (TCF7L2) Variants With Type 2 Diabetes in a Finnish Sample.

Published in:

Diabetes, 2006, v. 55, n. 9, p. 2649, doi. 10.2337/db06-0341

By:

Scott, Laura J.;
Bonnycastle, Lori L.;
Willer, Cristen J.;
Sprau, Andrew G.;
Jackson, Anne U.;
Narisu, Narisu;
Duren, William L.;
Chines, Peter S.;
Stringham, Heather M.;
Erdos, Michael R.;
Valle, Timo T.;
Tuomilehto, Jaakko;
Bergman, Richard N.;
Mohlke, Karen L.;
Collins, Francis S.;
Boehnke, Michael

Publication type:

Article

Common Variants in Maturity-Onset Diabetes of the Young Genes Contribute to Risk of Type 2 Diabetes in Finns.

Published in:

Diabetes, 2006, v. 55, n. 9, p. 2534, doi. 10.2337/db06-0178

By:

Bonnycastle, Lori L.;
Willer, Cristen J.;
Conneely, Karen N.;
Jackson, Anne U.;
Burrill, Cecily P.;
Watanabe, Richard M.;
Chines, Peter S.;
Narisu, Narisu;
Scott, Laura J.;
Enloe, Sareena T.;
Swift, Amy J.;
Duren, William L.;
Stringham, Heather M.;
Erdos, Michael R.;
Riebow, Nancy L.;
Buchanan, Thomas A.;
Valle, Timo T.;
Tuomilehto, Jaakko;
Bergman, Richard N.;
Mohlke, Karen L.

Publication type:

Article

Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes.

Published in:

2004

By:

Silander, Kaisa;
Mohlke, Karen L.;
Scott, Laura J.;
Peck, Erin C.;
Hollstein, Pablo;
Skol, Andrew D.;
Jackson, Anne U.;
Deloukas, Panagiotis;
Hunt, Sarah;
Stavrides, George;
Chines, Peter S.;
Erdos, Michael R.;
Narisu, Narisu;
Conneely, Karen N.;
Li, Chun;
Fingerlin, Tasha E.;
Dhanjal, Sharanjeet K.;
Valle, Timo T.;
Bergman, Richard N.;
Tuomilehto, Jaakko

Publication type:

journal article