Works by Moffatt, Miriam F.

Results: 63

iGWAS: Integrative Genome-Wide Association Studies of Genetic and Genomic Data for Disease Susceptibility Using Mediation Analysis.

Published in:

Genetic Epidemiology, 2015, v. 39, n. 5, p. 347, doi. 10.1002/gepi.21905

By:

Huang, Yen‐Tsung;
Liang, Liming;
Moffatt, Miriam F.;
Cookson, William O. C. M.;
Lin, Xihong

Publication type:

Article

A Polymorphism Affecting MYB Binding within the Promoter of the PDCD4 Gene is Associated with Severe Asthma in Children.

Published in:

Human Mutation, 2013, v. 34, n. 8, p. 1131, doi. 10.1002/humu.22340

By:

Binia, Aristea;
Van Stiphout, Nicole;
Liang, Liming;
Michel, Sven;
Bhavsar, Pankaj K.;
Fan Chung, K.;
Brightling, Chris E.;
Barnes, Peter J.;
Kabesch, Michael;
Bush, Andrew;
Cookson, William O.C.;
Moffatt, Miriam F.

Publication type:

Article

COPD is accompanied by co-ordinated transcriptional perturbation in the quadriceps affecting the mitochondria and extracellular matrix.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-29789-6

By:

Willis-Owen, Saffron A. G.;
Thompson, Anna;
Kemp, Paul R.;
Polkey, Michael I.;
Cookson, William O. C. M.;
Moffatt, Miriam F.;
Natanek, Samantha A.

Publication type:

Article

Association between quantitative traits underlying asthma and the HLA-DRB1 locus in a family-based population sample.

Published in:

European Journal of Human Genetics, 2001, v. 9, n. 5, p. 341, doi. 10.1038/sj.ejhg.5200636

By:

Moffatt, Miriam F;
Schou, Carsten;
Faux, Jennifer A;
Abecasis, Gonçalo R;
James, Alan;
Musk, A William;
Cookson, William OCM

Publication type:

Article

Profiling mycobacterial communities in pulmonary nontuberculous mycobacterial disease.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0208018

By:

Cowman, Steven A.;
James, Phillip;
Wilson, Robert;
Cookson, William O. C.;
Moffatt, Miriam F.;
Loebinger, Michael R.

Publication type:

Article

Comparison of the upper and lower airway microbiota in children with chronic lung diseases.

Published in:

PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0201156

By:

Ahmed, Bushra;
Cox, Michael J.;
Cuthbertson, Leah;
James, Phillip L.;
Cookson, William O. C.;
Davies, Jane C.;
Moffatt, Miriam F.;
Bush, Andrew

Publication type:

Article

Gene therapy for peanut allergy.

Published in:

Nature Medicine, 1999, v. 5, n. 4, p. 380, doi. 10.1038/7374

By:

Moffatt, Miriam F.;
Cookson, William O.C.

Publication type:

Article

A genome-wide association study of global gene expression.

Published in:

Nature Genetics, 2007, v. 39, n. 10, p. 1202, doi. 10.1038/ng2109

By:

Dixon, Anna L.;
Liming Liang;
Moffatt, Miriam F.;
Wei Chen;
Heath, Simon;
Wong, Kenny C. C.;
Taylor, Jenny;
Burnett, Edward;
Gut, Ivo;
Farrall, Martin;
Lathrop, G. Mark;
Abecasis, Gonçalo R.;
Cookson, William O. C.

Publication type:

Article

Gene polymorphism in Netherton and common atopic disease.

Published in:

Nature Genetics, 2001, v. 29, n. 2, p. 175, doi. 10.1038/ng728

By:

Walley, Andrew J.;
Chavanas, Stéphane;
Moffatt, Miriam F.;
Esnouf, Robert M.;
Ubhi, Baljinder;
Lawrence, Robert;
Wong, Kenny;
Abecasis, Gonçalo R;
Jones, E. Yvonne;
Harper, John I.;
Hovnanian, Alain;
Cookson, William O.C.M.

Publication type:

Article

Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci.

Published in:

Nature Genetics, 2001, v. 27, n. 4, p. 372, doi. 10.1038/86867

By:

Cookson, William O.C.M.;
Ubhi, Baljinder;
Lawrence, Robert;
Abecasis, Gonçalo R.;
Walley, Andrew J.;
Cox, Helen E.;
Coleman, Rosemary;
Leaves, Nicholas I.;
Trembath, Richard C.;
Moffatt, Miriam F.;
Harper, John I.

Publication type:

Article

Whole-Blood Gene Expression in Pulmonary Nontuberculous Mycobacterial Infection.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2018, v. 58, n. 4, p. 510, doi. 10.1165/rcmb.2017-0230OC

By:

Cowman, Steven A.;
Jacob, Joseph;
Hansell, David M.;
Kelleher, Peter;
Wilson, Robert;
Cookson, William O. C.;
Moffatt, Miriam F.;
Loebinger, Michael R.

Publication type:

Article

ORMDL3 regulates poly I:C induced inflammatory responses in airway epithelial cells.

Published in:

2021

By:

Laura, Gemma;
Liu, Yi;
Fernandes, Kieran;
Willis-Owen, Saffron A. G.;
Ito, Kazuhiro;
Cookson, William O.;
Moffatt, Miriam F.;
Zhang, Youming

Publication type:

journal article

An epigenome-wide association study of total serum immunoglobulin E concentration.

Published in:

Nature, 2015, v. 520, n. 7549, p. 670, doi. 10.1038/nature14125

By:

Liang, Liming;
Willis-Owen, Saffron A. G.;
Laprise, Catherine;
Wong, Kenny C. C.;
Davies, Gwyneth A.;
Hudson, Thomas J.;
Binia, Aristea;
Hopkin, Julian M.;
Yang, Ivana V.;
Grundberg, Elin;
Busche, Stephan;
Hudson, Marie;
Rönnblom, Lars;
Pastinen, Tomi M.;
Schwartz, David A.;
Lathrop, G. Mark;
Moffatt, Miriam F.;
Cookson, William O. C. M.

Publication type:

Article

Y disruption, autosomal hypomethylation and poor male lung cancer survival.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-91907-8

By:

Willis-Owen, Saffron A. G.;
Domingo-Sabugo, Clara;
Starren, Elizabeth;
Liang, Liming;
Freidin, Maxim B.;
Arseneault, Madeleine;
Zhang, Youming;
Lu, Shir Kiong;
Popat, Sanjay;
Lim, Eric;
Nicholson, Andrew G.;
Riazalhosseini, Yasser;
Lathrop, Mark;
Cookson, William O. C.;
Moffatt, Miriam F.

Publication type:

Article

Crosstalk with lung fibroblasts shapes the growth and therapeutic response of mesothelioma cells.

Published in:

Cell Death & Disease, 2023, v. 14, n. 11, p. 1, doi. 10.1038/s41419-023-06240-x

By:

Chrisochoidou, Yakinthi;
Roy, Rajat;
Farahmand, Pooyeh;
Gonzalez, Guadalupe;
Doig, Jennifer;
Krasny, Lukas;
Rimmer, Ella F.;
Willis, Anne E;
MacFarlane, Marion;
Huang, Paul H.;
Carragher, Neil O.;
Munro, Alison F.;
Murphy, Daniel J.;
Veselkov, Kirill;
Seckl, Michael J.;
Moffatt, Miriam F.;
Cookson, William O. C.;
Pardo, Olivier E.

Publication type:

Article

Late-Onset Bloodstream Infection and Perturbed Maturation of the Gastrointestinal Microbiota in Premature Infants.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0132923

By:

Shaw, Alexander G.;
Sim, Kathleen;
Randell, Paul;
Cox, Michael J.;
McClure, Zoë E.;
Li, Ming-Shi;
Donaldson, Hugo;
Langford, Paul R.;
Cookson, William O. C. M.;
Moffatt, Miriam F.;
Kroll, J. Simon

Publication type:

Article

Upper Airways Microbiota in Antibiotic-Naïve Wheezing and Healthy Infants from the Tropics of Rural Ecuador.

Published in:

PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046803

By:

Cardenas, Paul Andres;
Cooper, Philip J.;
Cox, Michael J.;
Chico, Martha;
Arias, Carlos;
Moffatt, Miriam F.;
Cookson, William Osmond;
Krauss-Etschmann, Susanne

Publication type:

Article

Improved Detection of Bifidobacteria with Optimised 16S rRNA-Gene Based Pyrosequencing.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032543

By:

Kathleen Sim;
Cox, Michael J.;
Wopereis, Harm;
Martin, Rocio;
Knol, Jan;
Ming-Shi Li;
Cookson, William O. C. M.;
Moffatt, Miriam F.;
Simon Kroll, J.

Publication type:

Article

Disordered Microbial Communities in Asthmatic Airways.

Published in:

PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008578

By:

Hilty, Markus;
Burke, Conor;
Pedro, Helder;
Cardenas, Paul;
Bush, Andy;
Bossley, Cara;
Davies, Jane;
Ervine, Aaron;
Poulter, Len;
Pachter, Lior;
Moffatt, Miriam F.;
Cookson, William O. C.

Publication type:

Article

Dynamic and Physical Clustering of Gene Expression during Epidermal Barrier Formation in Differentiating Keratinocytes.

Published in:

PLoS ONE, 2009, v. 4, n. 10, p. 1, doi. 10.1371/journal.pone.0007651

By:

Taylor, Jennifer M.;
Street, Teresa L.;
Hao, Lizhong;
Copley, Richard;
Taylor, Martin S.;
Hayden, Patrick J.;
Stolper, Gina;
Mott, Richard;
Hein, Jotun;
Moffatt, Miriam F.;
Cookson, William O. C. M.

Publication type:

Article

Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels.

Published in:

FASEB Journal, 2014, v. 28, n. 2, p. 923, doi. 10.1096/fj.13-240879

By:

Portelli, Michael A.;
Siedlinski, Mateusz;
Stewart, Ceri E.;
Postma, Dirkje S.;
Nieuwenhuis, Maartje A.;
Vonk, Judith M.;
Nurnberg, Peter;
Altmuller, Janine;
Moffatt, Miriam F.;
Wardlaw, Andrew J.;
Parker, Smart G.;
Connolly, Martin J.;
Koppelman, Gerard H.;
Sayers, Ian

Publication type:

Article

Changes in the respiratory microbiome during acute exacerbations of idiopathic pulmonary fibrosis.

Published in:

2017

By:

Molyneaux, Philip L.;
Cox, Michael J.;
Wells, Athol U.;
Ho Cheol Kim;
Wonjun Ji;
Cookson, William O. C.;
Moffatt, Miriam F.;
Dong Soon Kim;
Maher, Toby M.;
Kim, Ho Cheol;
Ji, Wonjun;
Kim, Dong Soon

Publication type:

Letter

MAP3K8 is a potential therapeutic target in airway epithelial inflammation.

Published in:

Journal of Inflammation, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12950-024-00400-2

By:

Chiu, Chih-Yung;
Willis-Owen, Saffron A. G.;
Wong, Kenny C.C.;
Farrow, Stuart N.;
Cookson, William O.C.;
Moffatt, Miriam F.;
Zhang, Youming

Publication type:

Article

Vitamin D levels and susceptibility to asthma, elevated immunoglobulin E levels, and atopic dermatitis: A Mendelian randomization study.

Published in:

2017

By:

Manousaki, Despoina;
Paternoster, Lavinia;
Standl, Marie;
Moffatt, Miriam F.;
Farrall, Martin;
Bouzigon, Emmanuelle;
Strachan, David P.;
Demenais, Florence;
Lathrop, Mark;
Cookson, William O. C. M.;
Richards, J. Brent

Publication type:

journal article

Respiratory Disease following Viral Lung Infection Alters the Murine Gut Microbiota.

Published in:

Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00182

By:

Groves, Helen T.;
Cuthbertson, Leah;
James, Phillip;
Moffatt, Miriam F.;
Cox, Michael J.;
Tregoning, John S.

Publication type:

Article

Chromosome 17q21 SNP and severe asthma.

Published in:

Journal of Human Genetics, 2011, v. 56, n. 1, p. 97, doi. 10.1038/jhg.2010.134

By:

Binia, Aristea;
Khorasani, Nadia;
Bhavsar, Pankaj K;
Adcock, Ian;
Brightling, Chris E;
Chung, K Fan;
Cookson, William O C;
Moffatt, Miriam F

Publication type:

Article

Sequencing the human microbiome in health and disease.

Published in:

Human Molecular Genetics, 2013, v. 22, n. R1, p. R88, doi. 10.1093/hmg/ddt398

By:

Cox, Michael J.;
Cookson, William O.C.M.;
Moffatt, Miriam F.

Publication type:

Article

Dysbiosis Anticipating Necrotizing Enterocolitis in Very Premature Infants.

Published in:

Clinical Infectious Diseases, 2015, v. 60, n. 3, p. 389, doi. 10.1093/cid/ciu822

By:

Kathleen Sim;
Shaw, Alexander G.;
Randell, Paul;
Cox, Michael J.;
McClure, Zoë E.;
Ming-Shi Li;
Haddad, Munther;
Langford, Paul R.;
Cookson, William O. C. M.;
Moffatt, Miriam F.;
Kroll, J. Simon

Publication type:

Article

The ORMDL3 Asthma Gene Regulates ICAM1 and Has Multiple Effects on Cellular Inflammation.

Published in:

2019

By:

Zhang, Youming;
Willis-Owen, Saffron A G;
Spiegel, Sarah;
Lloyd, Clare M;
Moffatt, Miriam F;
Cookson, William O C M

Publication type:

journal article

Host-Microbial Interactions in Idiopathic Pulmonary Fibrosis.

Published in:

2017

By:

Molyneaux, Philip L.;
Willis-Owen, Saffron A. G.;
Cox, Michael J.;
James, Phillip;
Cowman, Steven;
Loebinger, Michael;
Blanchard, Andrew;
Edwards, Lindsay M.;
Stock, Carmel;
Daccord, Cécile;
Renzoni, Elisabetta A.;
Wells, Athol U.;
Moffatt, Miriam F.;
Cookson, William O. C.;
Maher, Toby M.

Publication type:

journal article

Outside In: Sequencing the Lung Microbiome.

Published in:

2015

By:

Cox, Michael J;
Moffatt, Miriam F;
Cookson, William O C

Publication type:

commentary

Outside In: Sequencing the Lung Microbiome.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2015, v. 192, n. 4, p. 403, doi. 10.1164/rccm.201506-1138ed

By:

Cox, Michael J.;
Moffatt, Miriam F.;
Cookson, William O. C.

Publication type:

Article

The Role of Bacteria in the Pathogenesis and Progression of Idiopathic Pulmonary Fibrosis.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2014, v. 190, n. 8, p. 906, doi. 10.1164/rccm.201403-0541OC

By:

Molyneaux, Phillip L.;
Cox, Michael J.;
Willis-Owen, Saffron A. G.;
Mallia, Patrick;
Russell, Kirsty E.;
Russell, Anne-Marie;
Murphy, Elissa;
Johnston, Sebastian L.;
Schwartz, David A.;
Wells, Athol U.;
Cookson, William O. C.;
Maher, Toby M.;
Moffatt, Miriam F.

Publication type:

Article

Outgrowth of the Bacterial Airway Microbiome after Rhinovirus Exacerbation of Chronic Obstructive Pulmonary Disease.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2013, v. 188, n. 10, p. 1224, doi. 10.1164/rccm.201302-0341OC

By:

Molyneaux, Philip L.;
Mallia, Patrick;
Cox, Michael J.;
Footitt, Joseph;
Willis-Owen, Saffron A. G.;
Homola, Daniel;
Trujillo-Torralbo, Maria-Belen;
Elkin, Sarah;
Kon, Onn Min;
Cookson, William O. C.;
Moffatt, Miriam F.;
Johnston, Sebastian L.

Publication type:

Article

Global gene regulation during activation of immunoglobulin class switching in human B cells.

Published in:

Scientific Reports, 2016, p. 37988, doi. 10.1038/srep37988

By:

Zhang, Youming;
Fear, David J.;
Willis-Owen, Saffron A. G.;
Cookson, William O.;
Moffatt, Miriam F.

Publication type:

Article

A genome scan for loci influencing total serum immunoglobulin levels: possible linkage of IgA to the chromosome 13 atopy locus.

Published in:

Human Molecular Genetics, 1998, v. 7, n. 1, p. 27, doi. 10.1093/hmg/7.1.27

By:

Wiltshire, Steven;
Bhattacharyya, Sumit;
Faux, Jennie A.;
Leaves, Nicholas I.;
Daniels, Susan E.;
Moffatt, Miriam F.;
James, Alan;
Musk, A. William;
Cookson, William O. C. M.

Publication type:

Article

Tumour Necrosis Factor Haplotypes and Asthma.

Published in:

Human Molecular Genetics, 1997, v. 6, n. 4, p. 551, doi. 10.1093/hmg/6.4.551

By:

Moffatt, Miriam F.;
Cookson, William O. C. M.

Publication type:

Article

The impact of persistent bacterial bronchitis on the pulmonary microbiome of children.

Published in:

PLoS ONE, 2017, v. 12, n. 12, p. 1, doi. 10.1371/journal.pone.0190075

By:

Cuthbertson, Leah;
Craven, Vanessa;
Bingle, Lynne;
Cookson, William O. C. M.;
Everard, Mark L.;
Moffatt, Miriam F.

Publication type:

Article

Longitudinal assessment of sputum microbiome by sequencing of the 16S rRNA gene in non-cystic fibrosis bronchiectasis patients.

Published in:

PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0170622

By:

Cox, Michael J.;
Turek, Elena M.;
Hennessy, Catherine;
Mirza, Ghazala K.;
James, Phillip L.;
Coleman, Meg;
Jones, Andrew;
Wilson, Robert;
Bilton, Diana;
Cookson, William O. C.;
Moffatt, Miriam F.;
Loebinger, Michael R.

Publication type:

Article

Presence of pleomorphic features but not growth patterns improves prognostic stratification of epithelioid malignant pleural mesothelioma by 2‐tier nuclear grade.

Published in:

Histopathology, 2020, v. 77, n. 3, p. 423, doi. 10.1111/his.14127

By:

Zhang, Yu Z;
Brambilla, Cecilia;
Molyneaux, Philip L;
Rice, Alexandra;
Robertus, Jan L;
Jordan, Simon;
Lim, Eric;
Lang‐Lazdunski, Loic;
Begum, Sofina;
Dusmet, Michael;
Anikin, Vladimir;
Beddow, Emma;
Finch, Jonathan;
Asadi, Nizar;
Popat, Sanjay;
Quesne, John L;
Husain, Aliya N;
Cookson, William O C M;
Moffatt, Miriam F;
Nicholson, Andrew G

Publication type:

Article

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease.

Published in:

Human Molecular Genetics, 2005, v. 14, n. 10, p. 1245, doi. 10.1093/hmg/ddi135

By:

McGovern, Dermot P.B.;
Hysi, Pirro;
Ahmad, Tariq;
van Heel, David A.;
Moffatt, Miriam F.;
Carey, Alisoun;
Cookson, William O.C.;
Jewell, Derek P.

Publication type:

Article

NOD1 variation, immunoglobulin E and asthma.

Published in:

Human Molecular Genetics, 2005, v. 14, n. 7, p. 935, doi. 10.1093/hmg/ddi087

By:

Hysi, Pirro;
Kabesch, Michael;
Moffatt, Miriam F.;
Schedel, Michaela;
Carr, David;
Zhang, Youming;
Boardman, Brenda;
von Mutius, Erika;
Weiland, Stephan K.;
Leupold, Wolfgang;
Fritzsch, Christian;
Klopp, Norman;
Musk, A. William;
James, Alan;
Nunez, Gabriel;
Inohara, Naohiro;
Cookson, William O.C.

Publication type:

Article

LD mapping of maternally and non-maternally derived alleles and atopy in FcɛRI-β.

Published in:

Human Molecular Genetics, 2003, v. 12, n. 20, p. 2577, doi. 10.1093/hmg/ddg290

By:

Traherne, James A.;
Hill, Michael R.;
Hysi, Pirro;
D'Amato, Mauro;
Broxholme, John;
Mott, Richard;
Moffatt, Miriam F.;
Cookson, William O.C.M.

Publication type:

Article

Atopy, respiratory function and HLA-DR in Aboriginal Australians.

Published in:

Human Molecular Genetics, 2003, v. 12, n. 6, p. 625, doi. 10.1093/hmg/ddg059

By:

Moffatt, Miriam F.;
Faux, Jennie A.;
Lester, Susan;
Paré, Peter;
McCluskey, James;
Spargo, Randy;
James, Alan;
Musk, A. William;
Cookson, William O. C. M.

Publication type:

Article

Filaggrin Mutations in Children with Severe Atopic Dermatitis.

Published in:

Journal of Investigative Dermatology, 2007, v. 127, n. 7, p. 1667, doi. 10.1038/sj.jid.5700739

By:

Morar, Nilesh;
Cookson, William O. C. M.;
Harper, John I.;
Moffatt, Miriam F.

Publication type:

Article

Investigation of the Chromosome 17q25 PSORS2 Locus in Atopic Dermatitis.

Published in:

Journal of Investigative Dermatology, 2006, v. 126, n. 3, p. 603, doi. 10.1038/sj.jid.5700108

By:

Morar, Nilesh;
Bowcock, Anne M.;
Harper, John I.;
Cookson, William O. C. M.;
Moffatt, Miriam F.

Publication type:

Article

Allergy to Dermatophagoides in a Group of Spanish Gypsies: Genetic Restrictions.

Published in:

International Archives of Allergy & Immunology, 2001, v. 125, n. 4, p. 297, doi. 10.1159/000053830

By:

Cárdaba, Blanca;
Moffatt, Miriam F.;
Fernández, Eduardo;
Jurado, Aurora;
Rojo, Marta;
García, Milagros;
Ansotegui, Ignacio J.;
Cortegano, Isabel;
Arrieta, Ignacio;
Etxenagusia, Miguel A.;
del Pozo, Victoria;
Urraca, Javier;
Aceituno, Esther;
Gallardo, Soledad;
Palomino, Pilar;
Cookson, William;
Lahoz, Carlos

Publication type:

Article

Gene Identification in Asthma and Allergy.

Published in:

International Archives of Allergy & Immunology, 1998, v. 116, n. 4, p. 247, doi. 10.1159/000023952

By:

Moffatt, Miriam F.;
Cookson, William O.C.M.

Publication type:

Article

In the Wrong Place at the Wrong Time: Microbial Misplacement and Acute Respiratory Distress Syndrome.

Published in:

2020

By:

Cookson, William O. C. M.;
Moffatt, Miriam F.

Publication type:

Editorial

Reagent and laboratory contamination can critically impact sequence-based microbiome analyses

Published in:

BMC Biology, 2014, v. 12, n. 1, p. 87, doi. 10.1186/s12915-014-0087-z

By:

Salter, Susannah J;
Cox, Michael J;
Turek, Elena M;
Calus, Szymon T;
Cookson, William O;
Moffatt, Miriam F;
Turner, Paul;
Parkhill, Julian;
Loman, Nicholas J;
Walker, Alan W

Publication type:

Article