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Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.
- Published in:
- Molecular Systems Biology, 2024, v. 20, n. 6, p. 719, doi. 10.1038/s44320-024-00032-x
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- Publication type:
- Article
Identifying human pre-mRNA cleavage and polyadenylation factors by genome-wide CRISPR screens using a dual fluorescence readthrough reporter.
- Published in:
- Nucleic Acids Research, 2024, v. 52, n. 8, p. 4483, doi. 10.1093/nar/gkae240
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- Article
Mapping of DDX11 genetic interactions defines sister chromatid cohesion as the major dependency.
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- G3: Genes | Genomes | Genetics, 2024, v. 14, n. 5, p. 1, doi. 10.1093/g3journal/jkae052
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- Publication type:
- Article
Salmonella exploits membrane reservoirs for invasion of host cells.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47183-x
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- Publication type:
- Article
Identification of acquired Notch3 dependency in metastatic Head and Neck Cancer.
- Published in:
- Communications Biology, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42003-023-04828-9
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- Publication type:
- Article
Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35118-3
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- Publication type:
- Article
Multi-level cellular and functional annotation of single-cell transcriptomes using scPipeline.
- Published in:
- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-04093-2
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- Article
Dual Antigen T Cell Engagers Targeting CA9 as an Effective Immunotherapeutic Modality for Targeting CA9 in Solid Tumors.
- Published in:
- Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.905768
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- Publication type:
- Article
Leveraging the CSF proteome toward minimally-invasive diagnostics surveillance of brain malignancies.
- Published in:
- Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac161
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- Article
Paralogous synthetic lethality underlies genetic dependencies of the cancer-mutated gene STAG2.
- Published in:
- Life Science Alliance, 2021, v. 4, n. 11, p. 1, doi. 10.26508/lsa.202101083
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- Article
Analysis of combinatorial CRISPR screens with the Orthrus scoring pipeline.
- Published in:
- Nature Protocols, 2021, v. 16, n. 10, p. 4766, doi. 10.1038/s41596-021-00596-0
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- Article
A method for benchmarking genetic screens reveals a predominant mitochondrial bias.
- Published in:
- Molecular Systems Biology, 2021, v. 17, n. 5, p. 1, doi. 10.15252/msb.202010013
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- Publication type:
- Article
Digital microfluidic isolation of single cells for -Omics.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-19394-5
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- Publication type:
- Article
Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9–Cas12a platform.
- Published in:
- Nature Biotechnology, 2020, v. 38, n. 5, p. 638, doi. 10.1038/s41587-020-0437-z
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- Publication type:
- Article
Identifying chemogenetic interactions from CRISPR screens with drugZ.
- Published in:
- Genome Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13073-019-0665-3
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- Publication type:
- Article
CRISPR screens are feasible in TP53 wild‐type cells.
- Published in:
- Molecular Systems Biology, 2019, v. 15, n. 8, p. N.PAG, doi. 10.15252/msb.20188679
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- Publication type:
- Article
Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells.
- Published in:
- Journal of Neuro-Oncology, 2019, v. 143, n. 3, p. 417, doi. 10.1007/s11060-019-03192-1
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- Publication type:
- Article
A rapid in vitro methodology for simultaneous target discovery and antibody generation against functional cell subpopulations.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37462-1
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- Publication type:
- Article
Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04649-z
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- Publication type:
- Article
Kin17 facilitates multiple double-strand break repair pathways that govern B cell class switching.
- Published in:
- Scientific Reports, 2016, p. 37215, doi. 10.1038/srep37215
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- Publication type:
- Article
Efficient generation of patient-matched malignant and normal primary cell cultures from clear cell renal cell carcinoma patients: clinically relevant models for research and personalized medicine.
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- 2016
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- Publication type:
- journal article
BAGEL: a computational framework for identifying essential genes from pooled library screens.
- Published in:
- BMC Bioinformatics, 2016, v. 17, p. 1, doi. 10.1186/s12859-016-1015-8
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- Publication type:
- Article
Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint.
- Published in:
- Genetics, 2015, v. 201, n. 3, p. 885, doi. 10.1534/genetics.115.180653
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- Publication type:
- Article
Selection of recombinant anti- SH3 domain antibodies by high-throughput phage display.
- Published in:
- Protein Science: A Publication of the Protein Society, 2015, v. 24, n. 11, p. 1890, doi. 10.1002/pro.2799
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- Article
Extensive mapping of an innate immune network with CRISPR.
- Published in:
- Molecular Systems Biology, 2015, v. 11, n. 7, p. 1, doi. 10.15252/msb.20156373
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- Publication type:
- Article
CYCLoPs: A Comprehensive Database Constructed from Automated Analysis of Protein Abundance and Subcellular Localization Patterns in Saccharomyces cerevisiae.
- Published in:
- G3: Genes | Genomes | Genetics, 2015, v. 5, n. 6, p. 1223, doi. 10.1534/g3.115.017830
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- Publication type:
- Article
Differential regulation of FGFR3 by PTPN1 and PTPN2.
- Published in:
- Proteomics, 2015, v. 15, n. 2/3, p. 419, doi. 10.1002/pmic.201400259
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- Publication type:
- Article
A systematic approach to identify novel cancer drug targets using machine learning, inhibitor design and high-throughput screening.
- Published in:
- Genome Medicine, 2014, v. 6, n. 7, p. 42, doi. 10.1186/s13073-014-0057-7
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- Publication type:
- Article
Measuring error rates in genomic perturbation screens: gold standards for human functional genomics.
- Published in:
- Molecular Systems Biology, 2014, v. 10, n. 7, p. n/a, doi. 10.15252/msb.20145216
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- Publication type:
- Article
A genome scale overexpression screen to reveal drug activity in human cells.
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- Genome Medicine, 2014, v. 6, n. 4, p. 27, doi. 10.1186/gm549
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- Publication type:
- Article
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.
- Published in:
- Nature Methods, 2014, v. 11, n. 5, p. 585, doi. 10.1038/nmeth.2895
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- Publication type:
- Article
RNA interference screens to uncover membrane protein biology.
- Published in:
- Briefings in Functional Genomics, 2013, v. 12, n. 5, p. 422, doi. 10.1093/bfgp/elt022
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- Publication type:
- Article
MBNL proteins repress ES-cell-specific alternative splicing and reprogramming.
- Published in:
- Nature, 2013, v. 498, n. 7453, p. 241, doi. 10.1038/nature12270
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- Publication type:
- Article
Scaling up the systematic hunt for mammalian genetic interactions.
- Published in:
- Nature Methods, 2013, v. 10, n. 5, p. 397, doi. 10.1038/nmeth.2449
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- Publication type:
- Article
Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress.
- Published in:
- Nature Cell Biology, 2012, v. 14, n. 9, p. 966, doi. 10.1038/ncb2549
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- Publication type:
- Article
Suppression of Cancer Progression by MGAT1 shRNA Knockdown.
- Published in:
- PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0043721
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- Publication type:
- Article
A genome wide shRNA screen identifies α/β hydrolase domain containing 4 (ABHD4) as a novel regulator of anoikis resistance.
- Published in:
- Apoptosis, 2012, v. 17, n. 7, p. 666, doi. 10.1007/s10495-012-0723-4
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- Publication type:
- Article
COLT-Cancer: functional genetic screening resource for essential genes in human cancer cell lines.
- Published in:
- Nucleic Acids Research, 2012, p. D957, doi. 10.1093/nar/gkr959
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- Publication type:
- Article
SATB2 augments ΔNp63α in head and neck squamous cell carcinoma.
- Published in:
- EMBO Reports, 2010, v. 11, n. 10, p. 777, doi. 10.1038/embor.2010.125
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- Publication type:
- Article
Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens.
- Published in:
- EMBO Molecular Medicine, 2010, v. 2, n. 9, p. 371, doi. 10.1002/emmm.201000093
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- Publication type:
- Article
Dual Regulation by Pairs of Cyclin-Dependent Protein Kinases and Histone Deacetylases Controls G1 Transcription in Budding Yeast.
- Published in:
- PLoS Biology, 2009, v. 7, n. 9, p. 1, doi. 10.1371/journal.pbio.1000188
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- Publication type:
- Article
Building mammalian signalling pathways with RNAi screens.
- Published in:
- Nature Reviews Molecular Cell Biology, 2006, v. 7, n. 3, p. 177, doi. 10.1038/nrm1860
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- Publication type:
- Article
Late-G1 cyclin-CDK activity is essential for control of cell morphogenesis in budding yeast.
- Published in:
- Nature Cell Biology, 2004, v. 6, n. 1, p. 59, doi. 10.1038/ncb1078
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- Publication type:
- Article
The Global Transcriptional Activator of Saccharomyces cerevisiae, Gcr1p, Mediates the Response to Glucose by Stimulating Protein Synthesis and CLN-Dependent Cell Cycle Progression.
- Published in:
- Genetics, 2003, v. 165, n. 3, p. 1017, doi. 10.1093/genetics/165.3.1017
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- Publication type:
- Article
The protein kinase Pho85 is required for asymmetric accumulation of the Ash1 protein in Saccharomyces cerevisiae.
- Published in:
- Molecular Microbiology, 2001, v. 42, n. 2, p. 345, doi. 10.1046/j.1365-2958.2001.02601.x
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- Publication type:
- Article
Interactions between Pho85 cyclin-dependent kinase complexes and the Swi5 transcription factor in budding yeast.
- Published in:
- Molecular Microbiology, 2000, v. 35, n. 4, p. 825, doi. 10.1046/j.1365-2958.2000.01754.x
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- Publication type:
- Article