Works by Mobley, William C.


Results: 56
    1

    Safety, Tolerability, and Immunogenicity of the ACI-24 Vaccine in Adults With Down Syndrome: A Phase 1b Randomized Clinical Trial.

    Published in:
    JAMA Neurology, 2022, v. 79, n. 6, p. 565, doi. 10.1001/jamaneurol.2022.0983
    By:
    • Rafii, Michael S.;
    • Sol, Olivier;
    • Mobley, William C.;
    • Delpretti, Saskia;
    • Skotko, Brian G.;
    • Burke, Anna D.;
    • Sabbagh, Marwan N.;
    • Yuan, Shauna H.;
    • Rissman, Robert A.;
    • Pulsifer, Margaret;
    • Evans, Casey;
    • Evans, A. Carol;
    • Beth, Gregory;
    • Fournier, Nicolas;
    • Gray, Julian A.;
    • dos Santos, Antonio Melo;
    • Hliva, Valerie;
    • Vukicevic, Marija;
    • Kosco-Vilbois, Marie;
    • Streffer, Johannes
    Publication type:
    Article
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    Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome.

    Published in:
    Nature Medicine, 2013, v. 19, n. 4, p. 473, doi. 10.1038/nm.3117
    By:
    • Wang, Xin;
    • Zhao, Yingjun;
    • Zhang, Xiaofei;
    • Badie, Hedieh;
    • Zhou, Ying;
    • Mu, Yangling;
    • Loo, Li Shen;
    • Cai, Lei;
    • Thompson, Robert C;
    • Yang, Bo;
    • Chen, Yaomin;
    • Johnson, Peter F;
    • Wu, Chengbiao;
    • Bu, Guojun;
    • Mobley, William C;
    • Zhang, Dongxian;
    • Gage, Fred H;
    • Ranscht, Barbara;
    • Zhang, Yun-wu;
    • Lipton, Stuart A
    Publication type:
    Article
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    Genetic dissection of the Down syndrome critical region.

    Published in:
    Human Molecular Genetics, 2015, v. 24, n. 22, p. 6540, doi. 10.1093/hmg/ddv364
    By:
    • Xiaoling Jiang;
    • Chunhong Liu;
    • Tao Yu;
    • Li Zhang;
    • Kai Meng;
    • Zhuo Xing;
    • Belichenko, Pavel V.;
    • Kleschevnikov, Alexander M.;
    • Pao, Annie;
    • Peresie, Jennifer;
    • Wie, Sarah;
    • Mobley, William C.;
    • Yu, Y. Eugene
    Publication type:
    Article
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    Human iPSC‐derived neuron modeling for the study of early‐onset Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S8, p. 1, doi. 10.1002/alz.094681
    By:
    • Valdes, Phoebe;
    • Caldwell, Andrew B.;
    • Liu, Qing;
    • Henry, Kenneth W.;
    • Fitzgerald, Michael Q;
    • Muralidharan, Koushik;
    • Ramachandran, Srinivasan;
    • Karch, Celeste M.;
    • Yuan, Shauna H;
    • Wagner, Steven L;
    • Goldstein, Lawrence S.B.;
    • Mobley, William C.;
    • Galasko, Douglas R.;
    • Subramaniam, Shankar
    Publication type:
    Article
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    Alzheimer's disease linked amyloid beta 1‐42 exerts product feedback inhibition on gamma‐secretase impairing downstream signaling cascades.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074247
    By:
    • Zoltowska, Katarzyna Marta;
    • Das, Utpal;
    • Lismont, Sam;
    • Enzlein, Thomas;
    • Maesako, Masato;
    • Houser, Mei CQ;
    • Franco, María Luisa;
    • Moreira, Diana Gomes;
    • Karachentsev, Dmitry;
    • Becker, Ann;
    • Hopf, Carsten;
    • Vilar, Marçal;
    • Berezovska, Oksana;
    • Mobley, William C;
    • Chávez‐Gutiérrez, Lucía
    Publication type:
    Article
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    Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1203, doi. 10.1002/alz.12463
    By:
    • Sawa, Mariko;
    • Overk, Cassia;
    • Becker, Ann;
    • Derse, Dominique;
    • Albay, Ricardo;
    • Weldy, Kim;
    • Salehi, Ahmad;
    • Beach, Thomas G.;
    • Doran, Eric;
    • Head, Elizabeth;
    • Yu, Y. Eugene;
    • Mobley, William C
    Publication type:
    Article
    44

    ACI‐24 in adults with Down syndrome: Results of a phase 1b, randomized, placebo‐controlled study.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057427
    By:
    • Rafii, Michael S;
    • Sol, Olivier;
    • Mobley, William C;
    • Skotko, Brian G.;
    • Burke, Anna D;
    • Sabbagh, Marwan N.;
    • Yuan, Shauna;
    • Rissman, Robert A.;
    • Delpretti, Saskia;
    • Beth, Greg;
    • Gray, Julian JG;
    • Melo dos Santos, Antonio;
    • Hliva, Valerie;
    • Vukicevic, Marija;
    • Kosco‐Vilbois, Marie;
    • Streffer, Johannes;
    • Pfeifer, Andrea;
    • Feldman, Howard
    Publication type:
    Article
    45

    Longitudinal investigation for enhancing Down Syndrome Research (LIFE‐DSR) Study: Tau PET and CSF sub‐studies.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057426
    By:
    • Hendrix, James A.;
    • Britton, Angela;
    • Christian, Bradley T.;
    • Ledesma, Duvia Lara;
    • Egan, Michael F.;
    • Feldman, Howard;
    • Hendrix, Suzanne B.;
    • Herring, W. Joseph;
    • Kennedy, Matthew E.;
    • Nicodemus‐Johnson, Jessie;
    • Revta, Carolyn;
    • Struyk, Arie;
    • Sur, Cyrille;
    • Mobley, William C.
    Publication type:
    Article
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    ACI‐24 vaccine in adults with Down syndrome: Human: Putative therapeutic results for Alzheimer's and related dementias.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.038678
    By:
    • Rafii, Michael S;
    • Mobley, William C;
    • Skotko, Brian G.;
    • Sabbagh, Marwan N.;
    • Burke, Anna D.;
    • Yuan, Shauna;
    • Rissman, Robert A.;
    • Chavez, Ronelyn;
    • Delpretti, Saskia;
    • Sol, Olivier;
    • Beth, Greg;
    • Gray, Julian JG;
    • dos Santos, Antonio Melo;
    • Hliva, Valerie;
    • Vukicevic, Marija;
    • Kosco‐Vilbois, Marie;
    • Pfeifer, Andrea;
    • Feldman, Howard H.
    Publication type:
    Article
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