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Using fluorodeoxythymidine to monitor anti-EGFR inhibitor therapy in squamous cell carcinoma xenografts.
Published in:
Head & Neck, 2008, v. 30, n. 6, p. 790, doi. 10.1002/hed.20770
By:
- Atkinson, David M.;
- Clarke, Michelle J.;
- Mladek, Ann C.;
- Carlson, Brett L.;
- Trump, David P.;
- Jacobson, Mark S.;
- Kemp, Brad J.;
- Lowe, Val J.;
- Sarkaria, Jann N.
Publication type:
Article
Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07334-3
By:
- Randall, Elizabeth C.;
- Emdal, Kristina B.;
- Laramy, Janice K.;
- Kim, Minjee;
- Roos, Alison;
- Calligaris, David;
- Regan, Michael S.;
- Gupta, Shiv K.;
- Mladek, Ann C.;
- Carlson, Brett L.;
- Johnson, Aaron J.;
- Lu, Fa-Ke;
- Xie, X. Sunney;
- Joughin, Brian A.;
- Reddy, Raven J.;
- Peng, Sen;
- Abdelmoula, Walid M.;
- Jackson, Pamela R.;
- Kolluri, Aarti;
- Kellersberger, Katherine A.
Publication type:
Article
Multimodal platform for assessing drug distribution and response in clinical trials.
Published in:
Neuro-Oncology, 2022, v. 24, n. 1, p. 64, doi. 10.1093/neuonc/noab197
By:
- Lopez, Begoña G C;
- Kohale, Ishwar N;
- Du, Ziming;
- Korsunsky, Ilya;
- Abdelmoula, Walid M;
- Dai, Yang;
- Stopka, Sylwia A;
- Gaglia, Giorgio;
- Randall, Elizabeth C;
- Regan, Michael S;
- Basu, Sankha S;
- Clark, Amanda R;
- Marin, Bianca-Maria;
- Mladek, Ann C;
- Burgenske, Danielle M;
- Agar, Jeffrey N;
- Supko, Jeffrey G;
- Grossman, Stuart A;
- Nabors, Louis B;
- Raychaudhuri, Soumya
Publication type:
Article
Heterogeneous delivery across the blood-brain barrier limits the efficacy of an EGFR-targeting antibody drug conjugate in glioblastoma.
Published in:
Neuro-Oncology, 2021, v. 23, n. 12, p. 2042, doi. 10.1093/neuonc/noab133
By:
- Marin, Bianca-Maria;
- Porath, Kendra A;
- Jain, Sonia;
- Kim, Minjee;
- Conage-Pough, Jason E;
- Oh, Ju-Hee;
- Miller, Caitlyn L;
- Talele, Surabhi;
- Kitange, Gaspar J;
- Tian, Shulan;
- Burgenske, Danielle M;
- Mladek, Ann C;
- Gupta, Shiv K;
- Decker, Paul A;
- McMinn, Madison H;
- Stopka, Sylwia A;
- Regan, Michael S;
- He, Lihong;
- Carlson, Brett L;
- Bakken, Katrina
Publication type:
Article
Molecular profiling of long-term IDH-wildtype glioblastoma survivors.
Published in:
Neuro-Oncology, 2019, v. 21, n. 11, p. 1458, doi. 10.1093/neuonc/noz129
By:
- Burgenske, Danielle M;
- Yang, Jie;
- Decker, Paul A;
- Kollmeyer, Thomas M;
- Kosel, Matthew L;
- Mladek, Ann C;
- Caron, Alissa A;
- Vaubel, Rachael A;
- Gupta, Shiv K;
- Kitange, Gaspar J;
- Sicotte, Hugues;
- Youland, Ryan S;
- Remonde, Dioval;
- Voss, Jesse S;
- Fritcher, Emily G Barr;
- Kolsky, Kathryn L;
- Ida, Cristiane M;
- Meyer, Fredric B;
- Lachance, Daniel H;
- Parney, Ian J
Publication type:
Article
Xenograft-based, platform-independent gene signatures to predict response to alkylating chemotherapy, radiation, and combination therapy for glioblastoma.
Published in:
Neuro-Oncology, 2019, v. 21, n. 9, p. 1141, doi. 10.1093/neuonc/noz090
By:
- Zhao, Shuang G;
- Yu, Menggang;
- Spratt, Daniel E;
- Chang, S Laura;
- Feng, Felix Y;
- Kim, Michelle M;
- Speers, Corey W;
- Carlson, Brett L;
- Mladek, Ann C;
- Lawrence, Theodore S;
- Sarkaria, Jann N;
- Wahl, Daniel R
Publication type:
Article
INFLUENCE OF DRUG DELIVERY ON THERAPEUTIC BENEFIT IN GBM–CDK4 AND MDM2 INHIBITOR COMPARISON IN FLANK VERSUS ORTHOTOPIC MODELS AND COMPARISON OF BRAIN PENETRANT VERSUS IMPENETRANT PI3K/MTOR INHIBITORS.
Published in:
Neuro-Oncology, 2014, v. 16, n. suppl_3, p. iii33, doi. 10.1093/neuonc/nou208.40
By:
- Sarkaria, Jann N.;
- Pokorny, Jenny L.;
- Mladek, Ann C.;
- Parrish, Karen;
- Oberoi, Rajneet;
- Sio, Terence;
- Mittapalli, Rajendar K.;
- Elmquist, William F.
Publication type:
Article
Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models.
Published in:
Neuro-Oncology, 2013, v. 15, n. 6, p. 735, doi. 10.1093/neuonc/not010
By:
- Cen, Ling;
- Carlson, Brett L.;
- Pokorny, Jenny L.;
- Mladek, Ann C.;
- Grogan, Patrick T.;
- Schroeder, Mark A.;
- Decker, Paul A.;
- Anderson, S. Keith;
- Giannini, Caterina;
- Wu, Wenting;
- Ballman, Karla V.;
- Kitange, Gaspar J.;
- Sarkaria, Jann N.
Publication type:
Article
p16-Cdk4-Rb axis controls sensitivity to a cyclin-dependent kinase inhibitor PD0332991 in glioblastoma xenograft cells.
Published in:
Neuro-Oncology, 2012, v. 14, n. 7, p. 870, doi. 10.1093/neuonc/nos114
By:
- Cen, Ling;
- Carlson, Brett L.;
- Schroeder, Mark A.;
- Ostrem, Jamie L.;
- Kitange, Gaspar J.;
- Mladek, Ann C.;
- Fink, Stephanie R.;
- Decker, Paul A.;
- Wu, Wenting;
- Kim, Jung-Sik;
- Waldman, Todd;
- Jenkins, Robert B.;
- Sarkaria, Jann N.
Publication type:
Article
WSD-0922, a novel brain-penetrant inhibitor of epidermal growth factor receptor, promotes survival in glioblastoma mouse models.
Published in:
Neuro-Oncology Advances, 2023, v. 5, n. 1, p. 1, doi. 10.1093/noajnl/vdad066
By:
- Conage-Pough, Jason E;
- Stopka, Sylwia A;
- Oh, Ju-Hee;
- Mladek, Ann C;
- Burgenske, Danielle M;
- Regan, Michael S;
- Baquer, Gerard;
- Decker, Paul A;
- Carlson, Brett L;
- Bakken, Katrina K;
- Zhang, Jinqiang;
- Liu, Lily;
- Sun, Claire;
- Mu, Zhihua;
- Zhong, Wei;
- Tran, Nhan L;
- Elmquist, William F;
- Agar, Nathalie Y R;
- Sarkaria, Jann N;
- White, Forest M
Publication type:
Article
Convection enhanced delivery of EGFR targeting antibody-drug conjugates Serclutamab talirine and Depatux-M in glioblastoma patient-derived xenografts.
Published in:
Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac130
By:
- Porath, Kendra A.;
- Regan, Michael S.;
- Griffith, Jessica I.;
- Jain, Sonia;
- Stopka, Sylwia A.;
- Burgenske, Danielle M.;
- Bakken, Katrina K.;
- Carlson, Brett L.;
- Decker, Paul A.;
- Vaubel, Rachael A.;
- Dragojevic, Sonja;
- Mladek, Ann C.;
- Connors, Margaret A.;
- Zeng Hu;
- Lihong He;
- Kitange, Gaspar J.;
- Gupta, Shiv K.;
- Feldsien, Thomas M.;
- Lefebvre, Didier R.;
- Agar, Nathalie Y. R.
Publication type:
Article
PARP Inhibitors for Sensitization of Alkylation Chemotherapy in Glioblastoma: Impact of Blood-Brain Barrier and Molecular Heterogeneity.
Published in:
Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2018.00670
By:
- Gupta, Shiv K.;
- Smith, Emily J.;
- Mladek, Ann C.;
- Tian, Shulan;
- Decker, Paul A.;
- Kizilbash, Sani H.;
- Kitange, Gaspar J.;
- Sarkaria, Jann N.
Publication type:
Article
RBBP4-p300 axis modulates expression of genes essential for cell survival and is a potential target for therapy in glioblastoma.
Published in:
Neuro-Oncology, 2022, v. 24, n. 8, p. 1261, doi. 10.1093/neuonc/noac051
By:
- Mladek, Ann C;
- Yan, Huihuang;
- Tian, Shulan;
- Decker, Paul A;
- Burgenske, Danielle M;
- Bakken, Katrina;
- Hu, Zeng;
- He, Lihong;
- Connors, Margaret A;
- Carlson, Brett L;
- Wilson, Jonathan;
- Bommi-Reddy, Archana;
- Conery, Andy;
- Eckel-Passow, Jeanette E;
- Sarkaria, Jann N;
- Kitange, Gaspar J
Publication type:
Article
Preclinical modeling in glioblastoma patient-derived xenograft (GBM PDX) xenografts to guide clinical development of lisavanbulin—a novel tumor checkpoint controller targeting microtubules.
Published in:
Neuro-Oncology, 2022, v. 24, n. 3, p. 384, doi. 10.1093/neuonc/noab162
By:
- Burgenske, Danielle M;
- Talele, Surabhi;
- Pokorny, Jenny L;
- Mladek, Ann C;
- Bakken, Katrina K;
- Carlson, Brett L;
- Schroeder, Mark A;
- He, Lihong;
- Hu, Zeng;
- Gampa, Gautham;
- Kosel, Matthew L;
- Decker, Paul A;
- Kitange, Gaspar J;
- Schmitt-Hoffmann, Anne;
- Bachmann, Felix;
- Vaubel, Rachael A;
- Eckel-Passow, Jeanette E;
- Giannini, Caterina;
- McSheehy, Paul;
- Lane, Heidi A
Publication type:
Article
Delineation of MGMT Hypermethylation as a Biomarker for Veliparib-Mediated Temozolomide-Sensitizing Therapy of Glioblastoma.
Published in:
2016
By:
- Gupta, Shiv K.;
- Kizilbash, Sani H.;
- Carlson, Brett L.;
- Mladek, Ann C.;
- Boakye-Agyeman, Felix;
- Bakken, Katrina K.;
- Pokorny, Jenny L.;
- Schroeder, Mark A.;
- Decker, Paul A.;
- Ling Cen;
- Eckel-Passow, Jeanette E.;
- Sarkar, Gobinda;
- Ballman, Karla V.;
- Reid, Joel M.;
- Jenkins, Robert B.;
- Verhaak, Roeland G.;
- Sulman, Erik P.;
- Kitange, Gaspar J.;
- Sarkaria, Jann N.;
- Cen, Ling
Publication type:
journal article

Found: 15