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Recent Advances Addressing the Challenges of Precision Dosing.
- Published in:
- Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 3, p. 527, doi. 10.1002/cpt.3365
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- Publication type:
- Article
Rationale, Development, and Validation of HdxSim, a Clinical Decision Support Tool for Model‐Informed Precision Dosing of Hydroxyurea for Children with Sickle Cell Anemia.
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- Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 3, p. 670, doi. 10.1002/cpt.3119
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- Publication type:
- Article
84 Using Opportunistic Sampling and Remnant Blood Samples to Develop Pediatric Pharmacokinetic Models to Inform Antidepressant Dosing.
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- 2024
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- Publication type:
- Abstract
Forecasting Fetal Buprenorphine Exposure through Maternal–Fetal Physiologically Based Pharmacokinetic Modeling.
- Published in:
- Pharmaceutics, 2024, v. 16, n. 3, p. 375, doi. 10.3390/pharmaceutics16030375
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- Publication type:
- Article
Model‐Informed Vancomycin Dosing Optimization to Address Delayed Renal Maturation in Infants and Young Children with Critical Congenital Heart Disease.
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- Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 2, p. 239, doi. 10.1002/cpt.3095
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- Publication type:
- Article
Ceftriaxone Pharmacokinetics and Pharmacodynamic Target Attainment for Three Pediatric Patients Receiving Continuous Kidney Replacement Therapy.
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- Journal of Pediatric Pharmacology & Therapeutics, 2024, v. 29, n. 2, p. 180, doi. 10.5863/1551-6776-29.2.180
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- Publication type:
- Article
Tutorial on model selection and validation of model input into precision dosing software for model‐informed precision dosing.
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- CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 12, p. 1827, doi. 10.1002/psp4.13056
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- Article
Escitalopram and Sertraline Population Pharmacokinetic Analysis in Pediatric Patients.
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- Clinical Pharmacokinetics, 2023, v. 62, n. 11, p. 1621, doi. 10.1007/s40262-023-01294-8
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- Publication type:
- Article
Tacrolimus pharmacokinetics are influenced by CYP3A5, age, and concomitant fluconazole in pediatric kidney transplant patients.
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- CTS: Clinical & Translational Science, 2023, v. 16, n. 10, p. 1768, doi. 10.1111/cts.13571
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- Publication type:
- Article
Cefepime pharmacokinetics in critically ill children and young adults undergoing continuous kidney replacement therapy.
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- Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 9, p. 2140, doi. 10.1093/jac/dkad192
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- Publication type:
- Article
Real world population pharmacokinetic study in children and young adults with inflammatory bowel disease discovers novel blood and stool microbial predictors of vedolizumab clearance.
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- Alimentary Pharmacology & Therapeutics, 2023, v. 57, n. 5, p. 524, doi. 10.1111/apt.17277
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- Publication type:
- Article
Everolimus pharmacokinetics and exposure-response relationship in Japanese patients with advanced breast cancer.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.984002
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- Publication type:
- Article
Clinical implementation of pharmacogenetics and model‐informed precision dosing to improve patient care.
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- British Journal of Clinical Pharmacology, 2022, v. 88, n. 4, p. 1418, doi. 10.1111/bcp.14426
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- Publication type:
- Article
Antibodies‐to‐infliximab accelerate clearance while dose intensification reverses immunogenicity and recaptures clinical response in paediatric Crohn's disease.
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- Alimentary Pharmacology & Therapeutics, 2022, v. 55, n. 5, p. 593, doi. 10.1111/apt.16733
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- Publication type:
- Article
Physiologically‐Based Pharmacokinetic Modeling to Investigate the Effect of Maturation on Buprenorphine Pharmacokinetics in Newborns with Neonatal Opioid Withdrawal Syndrome.
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- Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 2, p. 496, doi. 10.1002/cpt.2458
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- Publication type:
- Article
Toward pharmacogenetic SLCO1B1‐guided dosing of methotrexate in arthritis using a murine Slco1b2 knockout model.
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- CTS: Clinical & Translational Science, 2021, v. 14, n. 6, p. 2267, doi. 10.1111/cts.13086
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- Publication type:
- Article
Population pharmacokinetics of vancomycin in paediatric patients with febrile neutropenia and augmented renal clearance: development of new dosing recommendations.
- Published in:
- 2021
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- Publication type:
- journal article
Paradoxical changes in mood-related behaviors on continuous social isolation after weaning.
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- Experimental Brain Research, 2021, v. 239, n. 8, p. 2537, doi. 10.1007/s00221-021-06149-x
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- Publication type:
- Article
Real‐World Infliximab Pharmacokinetic Study Informs an Electronic Health Record‐Embedded Dashboard to Guide Precision Dosing in Children with Crohn's Disease.
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- Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 6, p. 1639, doi. 10.1002/cpt.2148
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- Publication type:
- Article
Physiologic Indirect Response Modeling to Describe Buprenorphine Pharmacodynamics in Newborns Treated for Neonatal Opioid Withdrawal Syndrome.
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- Clinical Pharmacokinetics, 2021, v. 60, n. 2, p. 249, doi. 10.1007/s40262-020-00939-2
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- Publication type:
- Article
PK/PD Study of Mycophenolate Mofetil in Children With Systemic Lupus Erythematosus to Inform Model-Based Precision Dosing.
- Published in:
- Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.605060
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- Publication type:
- Article
A phase II study of continuous oral mTOR inhibitor everolimus for recurrent, radiographic-progressive neurofibromatosis type 1–associated pediatric low-grade glioma: a Neurofibromatosis Clinical Trials Consortium study.
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- Neuro-Oncology, 2020, v. 22, n. 10, p. 1527, doi. 10.1093/neuonc/noaa071
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- Publication type:
- Article
Molecular Adsorbent Recirculating System Therapy with Continuous Renal Replacement Therapy Enhanced Clearance of Piperacillin in a Pediatric Patient and Led to Failure to Attain Pharmacodynamic Targets.
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- Pharmacotherapy, 2020, v. 40, n. 10, p. 1061, doi. 10.1002/phar.2462
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- Publication type:
- Article
MTXPK.org: A Clinical Decision Support Tool Evaluating High‐Dose Methotrexate Pharmacokinetics to Inform Post‐Infusion Care and Use of Glucarpidase.
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- Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 3, p. 635, doi. 10.1002/cpt.1957
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- Publication type:
- Article
Influence of MRP3 Genetics and Hepatic Expression Ontogeny for Morphine Disposition in Neonatal and Pediatric Patients.
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- Journal of Clinical Pharmacology, 2020, v. 60, n. 8, p. 992, doi. 10.1002/jcph.1592
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- Publication type:
- Article
Population pharmacokinetic modelling of busulfan and the influence of body composition in paediatric Fanconi anaemia patients.
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- British Journal of Clinical Pharmacology, 2020, v. 86, n. 5, p. 933, doi. 10.1111/bcp.14202
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- Publication type:
- Article
Next Challenge From the Variance in Individual Physiologically‐Based Pharmacokinetic Model‐Predicted to Observed Morphine Concentration in Critically Ill Neonates.
- Published in:
- Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 2, p. 319, doi. 10.1002/cpt.1607
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- Publication type:
- Article
Electronic Health Record–Embedded Decision Support Platform for Morphine Precision Dosing in Neonates.
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- Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 1, p. 186, doi. 10.1002/cpt.1684
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- Publication type:
- Article
1543. Ceftaroline Model-based Dose Individualization in an Infant with Kidney Disease and Mediastinitis.
- Published in:
- Open Forum Infectious Diseases, 2019, v. 6, p. S563, doi. 10.1093/ofid/ofz360.1407
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- Publication type:
- Article
Robust clinical and laboratory response to hydroxyurea using pharmacokinetically guided dosing for young children with sickle cell anemia.
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- American Journal of Hematology, 2019, v. 94, n. 8, p. 871, doi. 10.1002/ajh.25510
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- Publication type:
- Article
Developmental Pharmacokinetics and Age-Appropriate Dosing Design of Milrinone in Neonates and Infants with Acute Kidney Injury Following Cardiac Surgery.
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- 2019
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- Publication type:
- journal article
Delayed methotrexate clearance in patients with acute lymphoblastic leukemia concurrently receiving dasatinib.
- Published in:
- 2019
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- Publication type:
- journal article
Influence of OCT1 Ontogeny and Genetic Variation on Morphine Disposition in Critically Ill Neonates: Lessons From PBPK Modeling and Clinical Study.
- Published in:
- Clinical Pharmacology & Therapeutics, 2019, v. 105, n. 3, p. 761, doi. 10.1002/cpt.1249
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- Publication type:
- Article
Dose modifications and pharmacokinetics of adjuvant cisplatin monotherapy while on hemodialysis for patients with hepatoblastoma.
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- 2019
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- Publication type:
- journal article
Phase 1 safety and pharmacokinetic study on the use of pioglitazone in critically ill patients with sepsis: a randomized clinical trial.
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- 2018
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- Publication type:
- clinical trial
Model‐based dosing with concentration feedback as an integral part of personalized hydroxycarbamide management.
- Published in:
- British Journal of Clinical Pharmacology, 2018, v. 84, n. 7, p. 1410, doi. 10.1111/bcp.13585
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- Publication type:
- Article
Bioequivalence between innovator and generic tacrolimus in liver and kidney transplant recipients: A randomized, crossover clinical trial.
- Published in:
- 2017
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- Publication type:
- journal article
Pharmacokinetics of IGF-1 in PAPP-A2-Deficient Patients, Growth Response, and Effects on Glucose and Bone Density.
- Published in:
- 2017
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- Publication type:
- journal article
Developmental pharmacokinetics of sirolimus: Implications for precision dosing in neonates and infants with complicated vascular anomalies.
- Published in:
- 2017
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- Publication type:
- journal article
Time in therapeutic range as a marker for thrombotic and bleeding outcomes in Fontan patients.
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- Journal of Thrombosis & Thrombolysis, 2017, v. 44, n. 1, p. 38, doi. 10.1007/s11239-017-1499-8
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- Publication type:
- Article
Pharmacokinetic and pharmacogenetic analysis of immunosuppressive agents after laparoscopic sleeve gastrectomy.
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- Clinical Transplantation, 2017, v. 31, n. 6, p. n/a, doi. 10.1111/ctr.12975
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- Publication type:
- Article
Population pharmacokinetics of temsirolimus and sirolimus in children with recurrent solid tumours: a report from the Children's Oncology Group.
- Published in:
- British Journal of Clinical Pharmacology, 2017, v. 83, n. 5, p. 1097, doi. 10.1111/bcp.13181
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- Publication type:
- Article
Development of a pharmacokinetic-guided dose individualization strategy for hydroxyurea treatment in children with sickle cell anaemia.
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- British Journal of Clinical Pharmacology, 2016, v. 81, n. 4, p. 742, doi. 10.1111/bcp.12851
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- Publication type:
- Article
Pharmacokinetics of meropenem in children receiving continuous renal replacement therapy: Validation of clinical trial simulations.
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- Journal of Clinical Pharmacology, 2016, v. 56, n. 3, p. 291, doi. 10.1002/jcph.601
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- Publication type:
- Article
An autopsy case of hemiconvulsion-hemiplegia-epilepsy syndrome manifesting as cerebral hemiatrophy in an elderly man.
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- Neuropathology, 2015, v. 35, n. 6, p. 592, doi. 10.1111/neup.12225
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- Publication type:
- Article
The Effects of Chronic Right Hemispheric Damage on the Allocation of Spatial Attention: Alterations of Accuracy and Reliability.
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- Journal of the International Neuropsychological Society, 2015, v. 21, n. 5, p. 373, doi. 10.1017/S1355617715000338
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- Publication type:
- Article
Sorafenib in a hepatocellular carcinoma patient with end-stage renal failure: A pharmacokinetic study.
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- Hepatology Research, 2014, v. 44, n. 6, p. 685, doi. 10.1111/hepr.12156
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- Publication type:
- Article
Developmental trajectory of intestinal MDR1/ABCB1 mRNA expression in children.
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- British Journal of Clinical Pharmacology, 2014, v. 77, n. 5, p. 910, doi. 10.1111/bcp.12211
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- Publication type:
- Article
Exposure-Toxicity Relationship of Sorafenib in Japanese Patients with Renal Cell Carcinoma and Hepatocellular Carcinoma.
- Published in:
- Clinical Pharmacokinetics, 2014, v. 53, n. 2, p. 185, doi. 10.1007/s40262-013-0108-z
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- Publication type:
- Article
Cerebrospinal fluid concentration of gefitinib and erlotinib in patients with non-small cell lung cancer.
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- Cancer Chemotherapy & Pharmacology, 2012, v. 70, n. 3, p. 399, doi. 10.1007/s00280-012-1929-4
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- Publication type:
- Article