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Ulcerative colitis endoscopic index of severity is associated with long-term prognosis in ulcerative colitis patients treated with infliximab.
Published in:
Digestive Endoscopy, 2016, v. 28, n. 6, p. 665, doi. 10.1111/den.12655
By:
- Saigusa, Keiichiro;
- Matsuoka, Katsuyoshi;
- Sugimoto, Shinya;
- Arai, Mari;
- Kiyohara, Hiroki;
- Takeshita, Kozue;
- Mizuno, Shinta;
- Mori, Kiyoto;
- Nanki, Kosaku;
- Takeshita, Tatsuya;
- Nakazato, Yoshihiro;
- Yajima, Tomoharu;
- Naganuma, Makoto;
- Hisamatsu, Tadakazu;
- Ogata, Haruhiko;
- Iwao, Yasushi;
- Kanai, Takanori
Publication type:
Article
Epigenetic regulation of T helper cells and intestinal pathogenicity.
Published in:
Seminars in Immunopathology, 2019, v. 41, n. 3, p. 379, doi. 10.1007/s00281-019-00732-9
By:
- Hagihara, Yuya;
- Yoshimatsu, Yusuke;
- Mikami, Yohei;
- Takada, Yoshiaki;
- Mizuno, Shinta;
- Kanai, Takanori
Publication type:
Article
Decreased Plasma Histidine Level Predicts Risk of Relapse in Patients with Ulcerative Colitis in Remission.
Published in:
PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0140716
By:
- Hisamatsu, Tadakazu;
- Ono, Nobukazu;
- Imaizumi, Akira;
- Mori, Maiko;
- Suzuki, Hiroaki;
- Uo, Michihide;
- Hashimoto, Masaki;
- Naganuma, Makoto;
- Matsuoka, Katsuyoshi;
- Mizuno, Shinta;
- Kitazume, Mina T.;
- Yajima, Tomoharu;
- Ogata, Haruhiko;
- Iwao, Yasushi;
- Hibi, Toshifumi;
- Kanai, Takanori
Publication type:
Article
Computer-Aided Prediction of Long-Term Prognosis of Patients with Ulcerative Colitis after Cytoapheresis Therapy.
Published in:
PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0131197
By:
- Takayama, Tetsuro;
- Okamoto, Susumu;
- Hisamatsu, Tadakazu;
- Naganuma, Makoto;
- Matsuoka, Katsuyoshi;
- Mizuno, Shinta;
- Bessho, Rieko;
- Hibi, Toshifumi;
- Kanai, Takanori
Publication type:
Article
Macrophages and Dendritic Cells Emerge in the Liver during Intestinal Inflammation and Predispose the Liver to Inflammation.
Published in:
PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0084619
By:
- Mikami, Yohei;
- Mizuno, Shinta;
- Nakamoto, Nobuhiro;
- Hayashi, Atsushi;
- Sujino, Tomohisa;
- Sato, Toshiro;
- Kamada, Nobuhiko;
- Matsuoka, Katsuyoshi;
- Hisamatsu, Tadakazu;
- Ebinuma, Hirotoshi;
- Hibi, Toshifumi;
- Yoshimura, Akihiko;
- Kanai, Takanori
Publication type:
Article
Mucosal concentrations of N‐acetyl‐5‐aminosalicylic acid related to endoscopic activity in ulcerative colitis patients with mesalamine.
Published in:
Journal of Gastroenterology & Hepatology, 2020, v. 35, n. 11, p. 1878, doi. 10.1111/jgh.15059
By:
- Fukuda, Tomohiro;
- Naganuma, Makoto;
- Takabayashi, Kaoru;
- Hagihara, Yuya;
- Tanemoto, Shun;
- Nomura, Ena;
- Yoshimatsu, Yusuke;
- Sugimoto, Shinya;
- Nanki, Kosaku;
- Mizuno, Shinta;
- Mikami, Yohei;
- Fukuhara, Kayoko;
- Sujino, Tomohisa;
- Mutaguchi, Makoto;
- Inoue, Nagamu;
- Ogata, Haruhiko;
- Iwao, Yasushi;
- Abe, Takayuki;
- Kanai, Takanori
Publication type:
Article
5-Aminosalicylic acid intolerance is associated with a risk of adverse clinical outcomes and dysbiosis in patients with ulcerative colitis.
Published in:
Intestinal Research, 2020, v. 18, n. 1, p. 69, doi. 10.5217/ir.2019.00084
By:
- Shinta Mizuno;
- Keiko Ono;
- Yohei Mikami;
- Makoto Naganuma;
- Tomohiro Fukuda;
- Kazuhiro Minami;
- Tatsuhiro Masaoka;
- Soichiro Terada;
- Takeshi Yoshida;
- Keiichiro Saigusa;
- Norimichi Hirahara;
- Hiroaki Miyata;
- Wataru Suda;
- Masahira Hattori;
- Takanori Kanai
Publication type:
Article
ß-(1,3)-Glucan derived from Candida albicans induces inflammatory cytokines from macrophages and lamina propria mononuclear cells derived from patients with Crohn's disease.
Published in:
Intestinal Research, 2018, v. 16, n. 3, p. 384, doi. 10.5217/ir.2018.16.3.384
By:
- Kiyoto Mori;
- Makoto Naganuma;
- Shinta Mizuno;
- Hiroaki Suzuki;
- Kitazume, Mina T.;
- Katsuyoshi Shimamura;
- Sayako Chiba;
- Akira Sugita;
- Katsuyoshi Matsuoka;
- Tadakazu Hisamatsu;
- Takanori Kanai
Publication type:
Article
Fecal microbiota transplantation for recurrent Clostridium difficile infection in a patient with ulcerative colitis.
Published in:
2018
By:
- Kosaku Nanki;
- Shinta Mizuno;
- Katsuyoshi Matsuoka;
- Keiko Ono;
- Shinya Sugimoto;
- Hiroki Kiyohara;
- Mari Arai;
- Moeko Nakashima;
- Kozue Takeshita;
- Keiichiro Saigusa;
- Mitsutoshi Senoh;
- Tadashi Fukuda;
- Makoto Naganuma;
- Haru Kato;
- Wataru Suda;
- Masahira Hattori;
- Takanori Kanai
Publication type:
Case Study
Single fecal microbiota transplantation failed to change intestinal microbiota and had limited effectiveness against ulcerative colitis in Japanese patients.
Published in:
Intestinal Research, 2017, v. 15, n. 1, p. 68, doi. 10.5217/ir.2017.15.1.68
By:
- Shinta Mizuno;
- Kosaku Nanki;
- Katsuyoshi Matsuoka;
- Keiichiro Saigusa;
- Keiko Ono;
- Mari Arai;
- Shinya Sugimoto;
- Hiroki Kiyohara;
- Moeko Nakashima;
- Kozue Takeshita;
- Makoto Naganuma;
- Wataru Suda;
- Masahira Hattori;
- Takanori Kanai
Publication type:
Article
Intramucosal poorly differentiated and signet‐ring cell components in patients with ulcerative colitis‐associated high‐grade dysplasia.
Published in:
Digestive Endoscopy, 2019, v. 31, n. 6, p. 706, doi. 10.1111/den.13482
By:
- Sugimoto, Shinya;
- Shimoda, Masayuki;
- Iwao, Yasushi;
- Mutaguchi, Makoto;
- Nanki, Kosaku;
- Mizuno, Shinta;
- Kameyama, Kaori;
- Ogata, Haruhiko;
- Naganuma, Makoto;
- Kanai, Takanori
Publication type:
Article
Leucine-Rich Alpha-2 Glycoprotein May Be Predictive of the Adalimumab Trough Level and Antidrug Antibody Development for Patients with Inflammatory Bowel Disease: A Sub-Analysis of the PLANET Study.
Published in:
Digestion, 2021, v. 102, n. 6, p. 929, doi. 10.1159/000517339
By:
- Yanai, Shunichi;
- Shinzaki, Shinichiro;
- Matsuoka, Katsuyoshi;
- Mizuno, Shinta;
- Iijima, Hideki;
- Naka, Tetsuji;
- Kanai, Takanori;
- Matsumoto, Takayuki
Publication type:
Article
Development of an Indigo Naturalis Suppository for Topical Induction Therapy in Patients with Ulcerative Colitis.
Published in:
Digestion, 2020, v. 101, n. 4, p. 492, doi. 10.1159/000501152
By:
- Yoshimatsu, Yusuke;
- Naganuma, Makoto;
- Sugimoto, Shinya;
- Tanemoto, Shun;
- Umeda, Satoko;
- Fukuda, Tomohiro;
- Nomura, Ena;
- Yoshida, Kosuke;
- Ono, Keiko;
- Mutaguchi, Makoto;
- Nanki, Kosaku;
- Mizuno, Shinta;
- Mikami, Yohei;
- Fukuhara, Kayoko;
- Sujino, Tomohisa;
- Takabayashi, Kaoru;
- Ogata, Haruhiko;
- Iwao, Yasushi;
- Kanai, Takanori
Publication type:
Article
Bifidobacterium -Rich Fecal Donor May Be a Positive Predictor for Successful Fecal Microbiota Transplantation in Patients with Irritable Bowel Syndrome.
Published in:
Digestion, 2017, v. 96, n. 1, p. 29, doi. 10.1159/000471919
By:
- Mizuno, Shinta;
- Masaoka, Tatsuhiro;
- Naganuma, Makoto;
- Kishimoto, Taishiro;
- Kitazawa, Momoko;
- Kurokawa, Shunya;
- Nakashima, Moeko;
- Takeshita, Kozue;
- Suda, Wataru;
- Mimura, Masaru;
- Hattori, Masahira;
- Kanai, Takanori
Publication type:
Article
Clinical Efficacy and Safety of Oral Qing-Dai in Patients with Ulcerative Colitis: A Single-Center Open-Label Prospective Study.
Published in:
Digestion, 2016, v. 93, n. 3, p. 193, doi. 10.1159/000444217
By:
- Sugimoto, Shinya;
- Naganuma, Makoto;
- Kiyohara, Hiroki;
- arai, Mari;
- Ono, Keiko;
- Mori, Kiyoto;
- Saigusa, Keiichiro;
- Nanki, Kosaku;
- Takeshita, Kozue;
- Takeshita, Tatsuya;
- Mutaguchi, Makoto;
- Mizuno, Shinta;
- Bessho, Rieko;
- Nakazato, Yoshihiro;
- Hisamatsu, Tadakazu;
- Inoue, Nagamu;
- Ogata, Haruhiko;
- Iwao, Yasushi;
- Kanai, Takanori
Publication type:
Article
Endoscopic Severity Predicts Long-Term Prognosis in Crohn's Disease Patients with Clinical Remission.
Published in:
Digestion, 2016, v. 93, n. 1, p. 66, doi. 10.1159/000441767
By:
- Naganuma, Makoto;
- Hisamatsu, Tadakazu;
- Matsuoka, Katsuyoshi;
- Kiyohara, Hiroki;
- arai, Mari;
- Sugimoto, Shinya;
- Mori, Kiyoto;
- Nanki, Kosaku;
- Ohno, Keiko;
- Mutaguchi, Makoto;
- Mizuno, Shinta;
- Bessho, Rieko;
- Nakazato, Yoshihiro;
- Hosoe, Naoki;
- Inoue, Nagamu;
- Iwao, Yasushi;
- Ogata, Haruhiko;
- Kanai, Takanori
Publication type:
Article
Risk and Management of Intra-Abdominal Abscess in Crohn's Disease Treated with Infliximab.
Published in:
Digestion, 2014, v. 89, n. 3, p. 201, doi. 10.1159/000360618
By:
- Yoneno, Kazuaki;
- Hisamatsu, Tadakazu;
- Matsuoka, Katsuyoshi;
- Okamoto, Susumu;
- Takayama, Tetsuro;
- Ichikawa, Riko;
- Sujino, Tomohisa;
- Miyoshi, Jun;
- Takabayashi, Kaoru;
- Mikami, Yohei;
- Mizuno, Shinta;
- Wada, Yasuyo;
- Yajima, Tomoharu;
- Naganuma, Makoto;
- Inoue, Nagamu;
- Iwao, Yasushi;
- Ogata, Haruhiko;
- Hasegawa, Hirotoshi;
- Kitagawa, Yuko;
- Hibi, Toshifumi
Publication type:
Article
Efficacy of Novel Ultrathin Single-Balloon Enteroscopy for Crohn's Disease: A Propensity Score-Matched Study.
Published in:
Gut & Liver, 2020, v. 14, n. 5, p. 619, doi. 10.5009/gnl19228
By:
- Kaoru Takabayashi;
- Naoki Hosoe;
- Motohiko Kato;
- Yukie Hayashi;
- Ryoichi Miyanaga;
- Kosaku Nanki;
- Kayoko Fukuhara;
- Yohei Mikami;
- Shinta Mizuno;
- Tomohisa Sujino;
- Makoto Mutaguchi;
- Makoto Naganuma;
- Naohisa Yahagi;
- Haruhiko Ogata;
- Takanori Kanai
Publication type:
Article
Fecal Microbiota Transplantation for Gastrointestinal Diseases.
Published in:
Keio Journal of Medicine, 2014, v. 63, n. 4, p. 69, doi. 10.2302/kjm.2014-0006-RE
By:
- Katsuyoshi Matsuoka;
- Shinta Mizuno;
- Atsushi Hayashi;
- Tadakazu Hisamatsu;
- Makoto Naganuma;
- Takanori Kanai
Publication type:
Article
Pharmacological effects of TAK-828F: an orally available RORγt inverse agonist, in mouse colitis model and human blood cells of inflammatory bowel disease.
Published in:
Inflammation Research, 2019, v. 68, n. 6, p. 493, doi. 10.1007/s00011-019-01234-y
By:
- Igaki, Keiko;
- Nakamura, Yoshiki;
- Tanaka, Masayuki;
- Mizuno, Shinta;
- Yoshimatsu, Yusuke;
- Komoike, Yusaku;
- Uga, Keiko;
- Shibata, Akira;
- Imaichi, Hisashi;
- Takayuki, Satou;
- Ishimura, Yoshimasa;
- Yamasaki, Masashi;
- Kanai, Takanori;
- Tsukimi, Yasuhiro;
- Tsuchimori, Noboru
Publication type:
Article
Leucine-rich alpha-2 glycoprotein is a potential biomarker to monitor disease activity in inflammatory bowel disease receiving adalimumab: PLANET study.
Published in:
2021
By:
- Shinzaki, Shinichiro;
- Matsuoka, Katsuyoshi;
- Tanaka, Hiroki;
- Takeshima, Fuminao;
- Kato, Shingo;
- Torisu, Takehiro;
- Ohta, Yuki;
- Watanabe, Kenji;
- Nakamura, Shiro;
- Yoshimura, Naoki;
- Kobayashi, Taku;
- Shiotani, Akiko;
- Hirai, Fumihito;
- Hiraoka, Sakiko;
- Watanabe, Mamoru;
- Matsuura, Minoru;
- Nishimoto, Shohei;
- Mizuno, Shinta;
- Iijima, Hideki;
- Takehara, Tetsuo
Publication type:
journal article
Significance of endoscopic deep small bowel evaluation using balloon-assisted enteroscopy for Crohn's disease in clinical remission.
Published in:
Journal of Gastroenterology, 2021, v. 56, n. 1, p. 25, doi. 10.1007/s00535-020-01737-0
By:
- Takabayashi, Kaoru;
- Hosoe, Naoki;
- Kato, Motohiko;
- Hayashi, Yukie;
- Nanki, Kosaku;
- Fukuhara, Kayoko;
- Mikami, Yohei;
- Mizuno, Shinta;
- Sujino, Tomohisa;
- Mutaguchi, Makoto;
- Naganuma, Makoto;
- Yahagi, Naohisa;
- Ogata, Haruhiko;
- Kanai, Takanori
Publication type:
Article
A nationwide, multi-center, retrospective study of symptomatic small bowel stricture in patients with Crohn's disease.
Published in:
2020
By:
- Bamba, Shigeki;
- Sakemi, Ryosuke;
- Fujii, Toshimitsu;
- Takeda, Teruyuki;
- Fujioka, Shin;
- Takenaka, Kento;
- Kitamoto, Hiroki;
- Umezawa, Shotaro;
- Sakuraba, Hirotake;
- Inokuchi, Toshihiro;
- Fukata, Norimasa;
- Mizuno, Shinta;
- Yamashita, Masaki;
- Shinzaki, Shinichiro;
- Tanaka, Hiroki;
- Takedatsu, Hidetoshi;
- Ozaki, Ryo;
- Moriya, Kei;
- Ishii, Manabu;
- Kinjo, Tetsu
Publication type:
journal article
Efficacy of apheresis as maintenance therapy for patients with ulcerative colitis in an open-label prospective multicenter randomised controlled trial.
Published in:
2020
By:
- Naganuma, Makoto;
- Yokoyama, Yoko;
- Motoya, Satoshi;
- Watanabe, Kenji;
- Sawada, Koji;
- Hirai, Fumito;
- Yamamoto, Takayuki;
- Hanai, Hiroyuki;
- Omori, Teppei;
- Kanai, Takanori;
- Hibi, Toshifumi;
- for the CAPTAIN study Group;
- Sugimoto, Shinya;
- Nanki, Kosaku;
- Mizuno, Shinta;
- Ogata, Haruhiko;
- Nagase, Kazuko;
- Nakamura, Shiro;
- Tanaka, Hiroki;
- Nasuno, Masanao
Publication type:
journal article
Indigo naturalis is effective even in treatment-refractory patients with ulcerative colitis: a post hoc analysis from the INDIGO study.
Published in:
2020
By:
- Naganuma, Makoto;
- Sugimoto, Shinya;
- Fukuda, Tomohiro;
- Mitsuyama, Keiichi;
- Kobayashi, Taku;
- Yoshimura, Naoki;
- Ohi, Hidehisa;
- Tanaka, Shinji;
- Andoh, Akira;
- Ohmiya, Naoki;
- Saigusa, Keiichiro;
- Yamamoto, Takayuki;
- Morohoshi, Yuichi;
- Ichikawa, Hitoshi;
- Matsuoka, Katsuyoshi;
- Hisamatsu, Tadakazu;
- Watanabe, Kenji;
- Mizuno, Shinta;
- Abe, Takayuki;
- Suzuki, Yasuo
Publication type:
journal article
NUDT15 codon 139 is the best pharmacogenetic marker for predicting thiopurine-induced severe adverse events in Japanese patients with inflammatory bowel disease: a multicenter study.
Published in:
2018
By:
- Kakuta, Yoichi;
- Kawai, Yosuke;
- Okamoto, Daisuke;
- Takagawa, Tetsuya;
- Ikeya, Kentaro;
- Sakuraba, Hirotake;
- Nishida, Atsushi;
- Nakagawa, Shoko;
- Miura, Miki;
- Toyonaga, Takahiko;
- Onodera, Kei;
- Shinozaki, Masaru;
- Ishiguro, Yoh;
- Mizuno, Shinta;
- Takahara, Masahiro;
- Yanai, Shunichi;
- Hokari, Ryota;
- Nakagawa, Tomoo;
- Araki, Hiroshi;
- Motoya, Satoshi
Publication type:
journal article
Factors predicting the therapeutic response to infliximab during maintenance therapy in Japanese patients with Crohn’s disease.
Published in:
PLoS ONE, 2018, v. 13, n. 10, p. 1, doi. 10.1371/journal.pone.0204632
By:
- Matsuoka, Katsuyoshi;
- Hamada, Shunsuke;
- Shimizu, Mikiko;
- Nanki, Kosaku;
- Mizuno, Shinta;
- Kiyohara, Hiroki;
- Arai, Mari;
- Sugimoto, Shinya;
- Iwao, Yasushi;
- Ogata, Haruhiko;
- Hisamatsu, Tadakazu;
- Naganuma, Makoto;
- Kanai, Takanori;
- Mochizuki, Mayumi;
- Hashiguchi, Masayuki
Publication type:
Article
Erratum: Leucine-rich Alpha-2 Glycoprotein is a Serum Biomarker of Mucosal Healing in Ulcerative Colitis.
Published in:
Journal of Crohn's & Colitis, 2019, v. 13, n. 12, p. 1590, doi. 10.1093/ecco-jcc/jjz100
By:
- Shinzaki, Shinichiro;
- Matsuoka, Katsuyoshi;
- Iijima, Hideki;
- Mizuno, Shinta;
- Serada, Satoshi;
- Fujimoto, Minoru;
- Arai, Norimitsu;
- Koyama, Noriyuki;
- Morii, Eiichi;
- Watanabe, Mamoru;
- Hibi, Toshifumi;
- Kanai, Takanori;
- Takehara, Tetsuo;
- Naka, Tetsuji
Publication type:
Article
Leucine-rich Alpha-2 Glycoprotein is a Serum Biomarker of Mucosal Healing in Ulcerative Colitis.
Published in:
Journal of Crohn's & Colitis, 2017, v. 11, n. 1, p. 84, doi. 10.1093/ecco-jcc/jjw132
By:
- Shinichiro Shinzaki;
- Katsuyoshi Matsuoka;
- Hideki Iijima;
- Shinta Mizuno;
- Satoshi Serada;
- Minoru Fujimoto;
- Norimitsu Arai;
- Noriyuki Koyama;
- Eiichi Morii;
- Mamoru Watanabe;
- Toshifumi Hibi;
- Takanori Kanai;
- Tetsuo Takehara;
- Tetsuji Naka
Publication type:
Article
The Ulcerative Colitis Endoscopic Index of Severity is Useful to Predict Medium- to Long-Term Prognosis in Ulcerative Colitis Patients with Clinical Remission.
Published in:
Journal of Crohn's & Colitis, 2016, v. 10, n. 11, p. 1303, doi. 10.1093/ecco-jcc/jjw104
By:
- Mari Arai;
- Makoto Naganuma;
- Shinya Sugimoto;
- Hiroki Kiyohara;
- Keiko Ono;
- Kiyoto Mori;
- Keiichiro Saigusa;
- Kosaku Nanki;
- Makoto Mutaguchi;
- Shinta Mizuno;
- Rieko Bessho;
- Yoshihiro Nakazato;
- Naoki Hosoe;
- Katsuyoshi Matsuoka;
- Nagamu Inoue;
- Haruhiko Ogata;
- Yasushi Iwao;
- Takanori Kanai
Publication type:
Article
Long‐term effect of NUDT15 R139C on hematologic indices in inflammatory bowel disease patients treated with thiopurine.
Published in:
Journal of Gastroenterology & Hepatology, 2019, v. 34, n. 10, p. 1751, doi. 10.1111/jgh.14693
By:
- Akiyama, Shintaro;
- Matsuoka, Katsuyoshi;
- Fukuda, Kyoko;
- Hamada, Shunsuke;
- Shimizu, Mikiko;
- Nanki, Kosaku;
- Mizuno, Shinta;
- Kiyohara, Hiroki;
- Arai, Mari;
- Sugimoto, Shinya;
- Iwao, Yasushi;
- Ogata, Haruhiko;
- Hisamatsu, Tadakazu;
- Naganuma, Makoto;
- Motobayashi, Maiko;
- Suzuki, Kohei;
- Takenaka, Kento;
- Fujii, Toshimitsu;
- Saito, Eiko;
- Nagahori, Masakazu
Publication type:
Article
The risk factor of clinical relapse in ulcerative colitis patients with low dose 5-aminosalicylic acid as maintenance therapy: A report from the IBD registry.
Published in:
PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0187737
By:
- Fukuda, Tomohiro;
- Naganuma, Makoto;
- Sugimoto, Shinya;
- Nanki, Kosaku;
- Mizuno, Shinta;
- Mutaguchi, Makoto;
- Nakazato, Yoshihiro;
- Inoue, Nagamu;
- Ogata, Haruhiko;
- Iwao, Yasushi;
- Kanai, Takanori
Publication type:
Article

Found: 32