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Is Sex as a Biological Variable Still Being Ignored in Preclinical Aging Research?
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2022, v. 77, n. 11, p. 2177, doi. 10.1093/gerona/glac042
By:
- Carmody, Colleen;
- Duesing, Charlotte G;
- Kane, Alice E;
- Mitchell, Sarah J
Publication type:
Article
Study of Longitudinal Aging in Mice: Presentation of Experimental Techniques.
Published in:
2021
By:
- Palliyaguru, Dushani L;
- Teixeira, Camila Vieira Ligo;
- Duregon, Eleonora;
- Germanio, Clara di;
- Alfaras, Irene;
- Mitchell, Sarah J;
- Navas-Enamorado, Ignacio;
- Shiroma, Eric J;
- Studenski, Stephanie;
- Bernier, Michel;
- Camandola, Simonetta;
- Price, Nathan L;
- Ferrucci, Luigi;
- Cabo, Rafael de;
- Vieira Ligo Teixeira, Camila;
- di Germanio, Clara;
- de Cabo, Rafael
Publication type:
journal article
Combining a High Dose of Metformin With the SIRT1 Activator, SRT1720, Reduces Life Span in Aged Mice Fed a High-Fat Diet.
Published in:
2020
By:
- Palliyaguru, Dushani L;
- Minor, Robin K;
- Mitchell, Sarah J;
- Palacios, Hector H;
- Licata, Jordan J;
- Ward, Theresa M;
- Abulwerdi, Gelareh;
- Elliott, Peter;
- Westphal, Christoph;
- Ellis, James L;
- Sinclair, David A;
- Price, Nathan L;
- Bernier, Michel;
- Cabo, Rafael de;
- Palacio, Hector H;
- de Cabo, Rafael
Publication type:
journal article
Of Aging Mice and Men: Gait Speed Decline Is a Translatable Trait, With Species-Specific Underlying Properties.
Published in:
2019
By:
- Bair, Woei-Nan;
- Petr, Michael;
- Alfaras, Irene;
- Mitchell, Sarah J;
- Bernier, Michel;
- Ferrucci, Luigi;
- Studenski, Stephanie A;
- Cabo, Rafael De;
- de Cabo, Rafael
Publication type:
journal article
Long-term Dietary Macronutrients and Hepatic Gene Expression in Aging Mice.
Published in:
2018
By:
- Gokarn, Rahul;
- Solon-Biet, Samantha M;
- Cogger, Victoria C;
- Cooney, Gregory J;
- Wahl, Devin;
- McMahon, Aisling C;
- Mitchell, James R;
- Mitchell, Sarah J;
- Hine, Christopher;
- Cabo, Rafael de;
- de Cabo, Rafael;
- Raubenheimer, David;
- Simpson, Stephen J;
- Le Couteur, David G
Publication type:
journal article
Breaking the Ceiling of Human Maximal Life span.
Published in:
2018
By:
- Ben-Haim, Moshe Shay;
- Kanfi, Yariv;
- Mitchell, Sarah J;
- Maoz, Noam;
- Vaughan, Kelli L;
- Amariglio, Ninette;
- Lerrer, Batia;
- Cabo, Rafael de;
- Rechavi, Gideon;
- Cohen, Haim Y;
- de Cabo, Rafael
Publication type:
journal article
A Comparison of Two Mouse Frailty Assessment Tools.
Published in:
2017
By:
- Kane, Alice E.;
- Huizer-Pajkos, Aniko;
- Mach, John;
- Mitchell, Sarah J.;
- de Cabo, Rafael;
- Le Couteur, David G.;
- Howlett, Susan E.;
- Hilmer, Sarah N.
Publication type:
journal article
Adverse Geriatric Outcomes Secondary to Polypharmacy in a Mouse Model: The Influence of Aging.
Published in:
2016
By:
- Huizer-Pajkos, Aniko;
- Kane, Alice E.;
- Howlett, Susan E.;
- Mach, John;
- Mitchell, Sarah J.;
- de Cabo, Rafael;
- Le Couteur, David G.;
- Hilmer, Sarah N.
Publication type:
journal article
Measures of Healthspan as Indices of Aging in Mice-A Recommendation.
Published in:
2016
By:
- Richardson, Arlan;
- Fischer, Kathleen E.;
- Speakman, John R.;
- de Cabo, Rafael;
- Mitchell, Sarah J.;
- Peterson, Charlotte A.;
- Rabinovitch, Peter;
- Chiao, Ying A.;
- Taffet, George;
- Miller, Richard A.;
- Rentería, René C.;
- Bower, James;
- Ingram, Donald K.;
- Ladiges, Warren C.;
- Yuji Ikeno;
- Sierra, Felipe;
- Austad, Steven N.;
- Ikeno, Yuji
Publication type:
journal article
Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index.
Published in:
2016
By:
- Kane, Alice E.;
- Hilmer, Sarah N.;
- Boyer, Dawn;
- Gavin, Kristan;
- Nines, Dawn;
- Howlett, Susan E.;
- de Cabo, Rafael;
- Mitchell, Sarah J.
Publication type:
journal article
Factors that Impact on Interrater Reliability of the Mouse Clinical Frailty Index.
Published in:
2015
By:
- Kane, Alice E;
- Hilmer, Sarah N;
- Huizer-Pajkos, Aniko;
- Mach, John;
- Nines, Dawn;
- Boyer, Dawn;
- Gavin, Kristan;
- Mitchell, Sarah J;
- de Cabo, Rafael
Publication type:
commentary
Age-Related Loss of Responsiveness to 2,5-Dimethoxy-4-Iodoamphetamine in Liver Sinusoidal Endothelial Cells.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2014, v. 69, n. 5, p. 514, doi. 10.1093/gerona/glt124
By:
- Cogger, Victoria C.;
- Mitchell, Sarah J.;
- Warren, Alessandra;
- de Cabo, Rafael;
- Le Couteur, David G.
Publication type:
Article
Age-Related Pseudocapillarization of the Liver Sinusoidal Endothelium Impairs the Hepatic Clearance of Acetaminophen in Rats.
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2011, v. 66A, n. 4, p. 400, doi. 10.1093/gerona/glq221
By:
- Mitchell, Sarah J.;
- Huizer-Pajkos, Aniko;
- Cogger, Victoria C.;
- McLachlan, Andrew J.;
- Le Couteur, David G.;
- Jones, Brett;
- de Cabo, Rafael;
- Hilmer, Sarah N.
Publication type:
Article
Characteristics of older and younger patients with suspected paracetamol toxicity.
Published in:
Australasian Journal on Ageing, 2012, v. 31, n. 3, p. 190, doi. 10.1111/j.1741-6612.2012.00598.x
By:
- Kane, Alice;
- Mitchell, Sarah J;
- Carroll, Peter R;
- Matthews, Slade;
- Hilmer, Sarah N
Publication type:
Article
A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.62952
By:
- Petr, Michael A.;
- Alfaras, Irene;
- Krawcyzk, Melissa;
- Bair, Woei-Nan;
- Mitchell, Sarah J.;
- Morrell, Christopher H.;
- Studenski, Stephanie A.;
- Price, Nathan L.;
- Fishbein, Kenneth W.;
- Spencer, Richard G.;
- Scheibye-Knudsen, Morten;
- Lakatta, Edward G.;
- Ferrucci, Luigi;
- Aon, Miguel A.;
- Bernier, Michel;
- Cabo, Rafael de
Publication type:
Article
Role and response of primary healthcare services in community end-of-life care during COVID-19: Qualitative study and recommendations for primary palliative care delivery.
Published in:
Palliative Medicine, 2023, v. 37, n. 2, p. 235, doi. 10.1177/02692163221140435
By:
- Turner, Nicola;
- Wahid, Aysha;
- Oliver, Phillip;
- Gardiner, Clare;
- Chapman, Helen;
- Khan, Dena;
- Boyd, Kirsty;
- Dale, Jeremy;
- Barclay, Stephen;
- Mayland, Catriona R;
- Mitchell, Sarah J
Publication type:
Article
An evaluation of the experiences of young people in Patient and Public Involvement for palliative care research.
Published in:
Palliative Medicine, 2021, v. 35, n. 4, p. 793, doi. 10.1177/0269216321999301
By:
- Mitchell, Sarah J;
- Slowther, Anne-Marie;
- Coad, Jane;
- Khan, Dena;
- Samani, Mohini;
- Dale, Jeremy
Publication type:
Article
Communication of palliative care needs in discharge letters from hospice providers to primary care: a multisite sequential explanatory mixed methods study.
Published in:
BMC Palliative Care, 2022, v. 21, n. 1, p. 1, doi. 10.1186/s12904-022-01038-8
By:
- Weetman, Katharine;
- Dale, Jeremy;
- Mitchell, Sarah J.;
- Ferguson, Claire;
- Finucane, Anne M.;
- Buckle, Peter;
- Arnold, Elizabeth;
- Clarke, Gemma;
- Karakitsiou, Despoina-Elvira;
- McConnell, Tracey;
- Sanyal, Nikhil;
- Schuberth, Anna;
- Tindle, Georgia;
- Perry, Rachel;
- Grewal, Bhajneek;
- Patynowska, Katarzyna A.;
- MacArtney, John I.
Publication type:
Article
The Influence of Old Age and Poloxamer-407 on the Hepatic Disposition of Diazepam in the Isolated Perfused Rat Liver.
Published in:
Pharmacology, 2012, v. 90, n. 5/6, p. 233, doi. 10.1159/000341724
By:
- Mitchell, Sarah J.;
- Huizer-Pajkos, Aniko;
- Cogger, Victoria C.;
- McLachlan, Andrew J.;
- Le Couteur, David G.;
- Jones, Brett;
- de Cabo, Rafael;
- Hilmer, Sarah N.
Publication type:
Article
Age-dependent impact of two exercise training regimens on genomic and metabolic remodeling in skeletal muscle and liver of male mice.
Published in:
NPJ Aging, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41514-022-00089-8
By:
- Bernier, Michel;
- Enamorado, Ignacio Navas;
- Gómez-Cabrera, Mari Carmen;
- Calvo-Rubio, Miguel;
- González-Reyes, Jose Antonio;
- Price, Nathan L.;
- Cortés-Rodríguez, Ana Belén;
- Rodríguez-Aguilera, Juan Carlos;
- Rodríguez-López, Sandra;
- Mitchell, Sarah J.;
- Murt, Kelsey N.;
- Kalafut, Krystle;
- Williams, Katrina M.;
- Ward, Christopher W.;
- Stains, Joseph P.;
- Brea-Calvo, Gloria;
- Villalba, Jose M.;
- Cortassa, Sonia;
- Aon, Miguel A.;
- de Cabo, Rafael
Publication type:
Article
Gentamicin pharmacokinetics in old age and frailty.
Published in:
British Journal of Clinical Pharmacology, 2011, v. 71, n. 2, p. 224, doi. 10.1111/j.1365-2125.2010.03825.x
By:
- Hilmer, Sarah N.;
- Tran, Kim;
- Rubie, Patrick;
- Wright, Jason;
- Gnjidic, Danijela;
- Mitchell, Sarah J.;
- Matthews, Slade;
- Carroll, Peter R.
Publication type:
Article
Estimation of lean body weight in older community-dwelling men.
Published in:
British Journal of Clinical Pharmacology, 2010, v. 69, n. 2, p. 118, doi. 10.1111/j.1365-2125.2009.03586.x
By:
- Mitchell, Sarah J.;
- Kirkpatrick, Carl M. J.;
- Le Couteur, David G.;
- Naganathan, Vasi;
- Sambrook, Philip N.;
- Seibel, Markus J.;
- Blyth, Fiona M.;
- Waite, Louise M.;
- Handelsman, David J.;
- Cumming, Robert G.;
- Hilmer, Sarah N.
Publication type:
Article
Age-Related Changes in the Hepatic Pharmacology and Toxicology of Paracetamol.
Published in:
Current Gerontology & Geratrics Research, 2011, p. 1, doi. 10.1155/2011/624156
By:
- Mitchell, Sarah J.;
- Kane, Alice E.;
- Hilmer, Sarah N.
Publication type:
Article
'You Look Like a 240 mg': Gentamicin Dosing at a Sydney Hospital.
Published in:
2011
By:
- Johnston, Claire F.;
- Carroll, Peter R.;
- Matthews, Slade T.;
- Mitchell, Sarah J.;
- Hilmer, Sarah N.
Publication type:
Journal Article
'You Look Like a 240 mg': Gentamicin Dosing at a Sydney Hospital.
Published in:
Journal of Pharmacy Practice & Research, 2011, v. 41, n. 4, p. 275, doi. 10.1002/j.2055-2335.2011.tb00103.x
By:
- Johnston, Claire F.;
- Carroll, Peter R.;
- Matthews, Slade T.;
- Mitchell, Sarah J.;
- Hilmer, Sarah N.
Publication type:
Article
Compliance with Paracetamol Prescribing Policies at a Sydney Hospital.
Published in:
Journal of Pharmacy Practice & Research, 2009, v. 39, n. 2, p. 122, doi. 10.1002/j.2055-2335.2009.tb00435.x
By:
- Mitchell, Sarah J.;
- Murnion, Bridin P.;
- Matthews, Slade T.;
- Hilmer, Sarah N.
Publication type:
Article
Metabolic and molecular framework for the enhancement of endurance by intermittent food deprivation.
Published in:
FASEB Journal, 2018, v. 32, n. 7, p. 3844, doi. 10.1096/fj.201701378RR
By:
- Marosi, Krisztina;
- Moehl, Keelin;
- Navas-Enamorado, Ignacio;
- Mitchell, Sarah J.;
- Yongqing Zhang;
- Lehrmann, Elin;
- Aon, Miguel A.;
- Cortassa, Sonia;
- Becker, Kevin G.;
- Mattson, Mark P.
Publication type:
Article
Metformin improves healthspan and lifespan in mice.
Published in:
Nature Communications, 2013, v. 4, n. 7, p. 2192, doi. 10.1038/ncomms3192
By:
- Martin-Montalvo, Alejandro;
- Mercken, Evi M.;
- Mitchell, Sarah J.;
- Palacios, Hector H.;
- Mote, Patricia L.;
- Scheibye-Knudsen, Morten;
- Gomes, Ana P.;
- Ward, Theresa M.;
- Minor, Robin K.;
- Blouin, Marie-José;
- Schwab, Matthias;
- Pollak, Michael;
- Zhang, Yongqing;
- Yu, Yinbing;
- Becker, Kevin G.;
- Bohr, Vilhelm A.;
- Ingram, Donald K.;
- Sinclair, David A.;
- Wolf, Norman S.;
- Spindler, Stephen R.
Publication type:
Article
Periprocedural Hydrogen Sulfide Therapy Improves Vascular Remodeling and Attenuates Vein Graft Disease.
Published in:
2020
By:
- Kip, Peter;
- Ming Tao;
- Trocha, Kaspar M.;
- MacArthur, Michael R.;
- Peters, Hendrika A. B.;
- Mitchell, Sarah J.;
- Mann, Charlotte G.;
- Sluiter, Thijs J.;
- Jonathan Jung;
- Patterson, Suzannah;
- Quax, Paul H. A.;
- de Vries, Margreet R.;
- Mitchell, James R.;
- Keith Ozaki, C.;
- Tao, Ming;
- Jung, Jonathan
Publication type:
journal article
Sex differences in pharmacological interventions and their effects on lifespan and healthspan outcomes: a systematic review.
Published in:
Frontiers in Aging, 2023, p. 1, doi. 10.3389/fragi.2023.1172789
By:
- Knufinke, Marie;
- MacArthur, Michael R.;
- Ewald, Collin Y.;
- Mitchell, Sarah J.
Publication type:
Article
The effect of ageing on isoniazid pharmacokinetics and hepatotoxicity in Fischer 344 rats.
Published in:
Fundamental & Clinical Pharmacology, 2016, v. 30, n. 1, p. 23, doi. 10.1111/fcp.12157
By:
- Mach, John;
- Huizer – Pajkos, Aniko;
- Mitchell, Sarah J.;
- McKenzie, Catriona;
- Phillips, Leo;
- Kane, Alice;
- Jones, Brett;
- Cabo, Rafael;
- Cogger, Victoria;
- Le Couteur, David G.;
- Hilmer, Sarah N.
Publication type:
Article
Loss of miR-451a enhances SPARC production during myogenesis.
Published in:
PLoS ONE, 2019, v. 14, n. 3, p. 1, doi. 10.1371/journal.pone.0214301
By:
- Munk, Rachel;
- Martindale, Jennifer L.;
- Yang, Xiaoling;
- Yang, Jen-Hao;
- Grammatikakis, Ioannis;
- Di Germanio, Clara;
- Mitchell, Sarah J.;
- de Cabo, Rafael;
- Lehrmann, Elin;
- Zhang, Yongqing;
- Becker, Kevin G.;
- Raz, Vered;
- Gorospe, Myriam;
- Abdelmohsen, Kotb;
- Panda, Amaresh C.
Publication type:
Article
SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass.
Published in:
Aging Cell, 2014, v. 13, n. 5, p. 787, doi. 10.1111/acel.12220
By:
- Mercken, Evi M.;
- Mitchell, Sarah J.;
- Martin‐Montalvo, Alejandro;
- Minor, Robin K.;
- Almeida, Maria;
- Gomes, Ana P.;
- Scheibye‐Knudsen, Morten;
- Palacios, Hector H.;
- Licata, Jordan J.;
- Zhang, Yongqing;
- Becker, Kevin G.;
- Khraiwesh, Husam;
- González‐Reyes, José A.;
- Villalba, José M.;
- Baur, Joseph A.;
- Elliott, Peter;
- Westphal, Christoph;
- Vlasuk, George P.;
- Ellis, James L.;
- Sinclair, David A.
Publication type:
Article
Animal models of frailty: current applications in clinical research.
Published in:
Clinical Interventions in Aging, 2016, v. 11, p. 1519, doi. 10.2147/CIA.S105714
By:
- Kane, Alice E.;
- Howlett, Susan E.;
- Hilmer, Sarah N.;
- Mach, John;
- Mitchell, Sarah J.;
- de Cabo, Rafael
Publication type:
Article
Publisher Correction: Age and life expectancy clocks based on machine learning analysis of mouse frailty.
Published in:
2020
By:
- Schultz, Michael B.;
- Kane, Alice E.;
- Mitchell, Sarah J.;
- MacArthur, Michael R.;
- Warner, Elisa;
- Vogel, David S.;
- Mitchell, James R.;
- Howlett, Susan E.;
- Bonkowski, Michael S.;
- Sinclair, David A.
Publication type:
Correction Notice
Age and life expectancy clocks based on machine learning analysis of mouse frailty.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18446-0
By:
- Schultz, Michael B.;
- Kane, Alice E.;
- Mitchell, Sarah J.;
- MacArthur, Michael R.;
- Warner, Elisa;
- Vogel, David S.;
- Mitchell, James R.;
- Howlett, Susan E.;
- Bonkowski, Michael S.;
- Sinclair, David A.
Publication type:
Article
Age and life expectancy clocks based on machine learning analysis of mouse frailty.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18446-0
By:
- Schultz, Michael B.;
- Kane, Alice E.;
- Mitchell, Sarah J.;
- MacArthur, Michael R.;
- Warner, Elisa;
- Vogel, David S.;
- Mitchell, James R.;
- Howlett, Susan E.;
- Bonkowski, Michael S.;
- Sinclair, David A.
Publication type:
Article
Sulfur Amino Acid Supplementation Abrogates Protective Effects of Caloric Restriction for Enhancing Bone Marrow Regrowth Following Ionizing Radiation.
Published in:
Nutrients, 2022, v. 14, n. 7, p. 1529, doi. 10.3390/nu14071529
By:
- Hine, Christopher;
- Treviño-Villarreal, J. Humberto;
- Mejia, Pedro;
- Longchamp, Alban;
- Brace, Lear E.;
- Harputlugil, Eylul;
- Mitchell, Sarah J.;
- Yang, Jie;
- Guan, Yihong;
- Maciejewski, Jaroslaw P.;
- Jha, Babal K.;
- Mitchell, James R.
Publication type:
Article
Short-Term Pre-Operative Protein Caloric Restriction in Elective Vascular Surgery Patients: A Randomized Clinical Trial.
Published in:
Nutrients, 2021, v. 13, n. 11, p. 4024, doi. 10.3390/nu13114024
By:
- Kip, Peter;
- Sluiter, Thijs J.;
- Moore, Jodene K.;
- Hart, Abby;
- Ruske, Jack;
- O'Leary, James;
- Jung, Jonathan;
- Tao, Ming;
- MacArthur, Michael R.;
- Heindel, Patrick;
- de Jong, Alwin;
- de Vries, Margreet R.;
- Burak, M. Furkan;
- Mitchell, Sarah J.;
- Mitchell, James R.;
- Ozaki, C. Keith
Publication type:
Article
Gut Microbiota Predicts Healthy Late-Life Aging in Male Mice.
Published in:
Nutrients, 2021, v. 13, n. 9, p. 3290, doi. 10.3390/nu13093290
By:
- Ke, Shanlin;
- Mitchell, Sarah J.;
- MacArthur, Michael R.;
- Kane, Alice E.;
- Sinclair, David A.;
- Venable, Emily M.;
- Chadaideh, Katia S.;
- Carmody, Rachel N.;
- Grodstein, Francine;
- Mitchell, James R.;
- Liu, Yangyu
Publication type:
Article

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