Works by Mitchell, Jacqueline C.

Results: 26

A Literature Review Examining the Effectiveness of At-Home Physical Activity on Controlling the Blood Pressure of African American Men in Baltimore, Maryland.

Published in:

Spectrum: A Journal on Black Men, 2020, v. 8, n. 1, p. 111, doi. 10.2979/spectrum.8.1.06

By:

Charles, Rashida;
Mitchell, Jacqueline C.

Publication type:

Article

Mechanisms of TDP-43 Proteinopathy Onset and Propagation.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 6004, doi. 10.3390/ijms22116004

By:

Chen, Han-Jou;
Mitchell, Jacqueline C.

Publication type:

Article

RNA-Seq is not required to determine stable reference genes for qPCR normalization.

Published in:

PLoS Computational Biology, 2022, v. 18, n. 2, p. 1, doi. 10.1371/journal.pcbi.1009868

By:

Sampathkumar, Nirmal Kumar;
Sundaram, Venkat Krishnan;
Danthi, Prakroothi S.;
Barakat, Rasha;
Solomon, Shiden;
Mondal, Mrityunjoy;
Carre, Ivo;
El Jalkh, Tatiana;
Padilla-Ferrer, Aïda;
Grenier, Julien;
Massaad, Charbel;
Mitchell, Jacqueline C.

Publication type:

Article

Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.

Published in:

Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0212-4

By:

Mitchell, Jacqueline C.;
Constable, Remy;
Eva So;
Vance, Caroline;
Scotter, Emma;
Glover, Leanne;
Hortobagyi, Tibor;
Arnold, Eveline S.;
Shuo-Chien Ling;
McAlonis, Melissa;
Da Cruz, Sandrine;
Polymenidou, Magda;
Tessarolo, Lino;
Cleveland, Don W.;
Shaw, Christopher E.

Publication type:

Article

Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.

Published in:

Science Translational Medicine, 2017, v. 9, n. 388, p. 1, doi. 10.1126/scitranslmed.aad9157

By:

Smith, Bradley N.;
Topp, Simon D.;
Fallini, Claudia;
Hideki Shibata;
Han-Jou Chen;
Troakes, Claire;
King, Andrew;
Ticozzi, Nicola;
Kenna, Kevin P.;
Soragia-Gkazi, Athina;
Miller, Jack W.;
Akane Sato;
Dias, Diana Marques;
Jeon, Maryangel;
Vance, Caroline;
Chun Hao Wong;
de Majo, Martina;
Kattuah, Wejdan;
Mitchell, Jacqueline C.;
Scotter, Emma L.

Publication type:

Article

Structural and functional studies of the VAPB-PTPIP51 ER-mitochondria tethering proteins in neurodegenerative diseases.

Published in:

2025

By:

Blair, Kerry;
Martinez-Serra, Raquel;
Gosset, Philippe;
Martín-Guerrero, Sandra M.;
Mórotz, Gábor M.;
Atherton, Joseph;
Mitchell, Jacqueline C.;
Markovinovic, Andrea;
Miller, Christopher C. J.

Publication type:

Literature Review

Stimulating VAPB-PTPIP51 ER-mitochondria tethering corrects FTD/ALS mutant TDP43 linked Ca<sup>2+</sup> and synaptic defects.

Published in:

Acta Neuropathologica Communications, 2024, v. 9, n. 1, p. 1, doi. 10.1186/s40478-024-01742-x

By:

Markovinovic, Andrea;
Martín-Guerrero, Sandra M.;
Mórotz, Gábor M.;
Salam, Shaakir;
Gomez-Suaga, Patricia;
Paillusson, Sebastien;
Greig, Jenny;
Lee, Younbok;
Mitchell, Jacqueline C.;
Noble, Wendy;
Miller, Christopher C.J.

Publication type:

Article

Age‐specific and compartment‐dependent changes in mitochondrial homeostasis and cytoplasmic viscosity in mouse peripheral neurons.

Published in:

Aging Cell, 2024, v. 23, n. 10, p. 1, doi. 10.1111/acel.14250

By:

Sleigh, James N.;
Mattedi, Francesca;
Richter, Sandy;
Annuario, Emily;
Ng, Kristal;
Steinmark, I. Emilie;
Ivanova, Iveta;
Darabán, István L.;
Joshi, Parth P.;
Rhymes, Elena R.;
Awale, Shirwa;
Yahioglu, Gokhan;
Mitchell, Jacqueline C.;
Suhling, Klaus;
Schiavo, Giampietro;
Vagnoni, Alessio

Publication type:

Article

Disruption of ER-mitochondria tethering and signalling in C9orf72-associated amyotrophic lateral sclerosis and frontotemporal dementia.

Published in:

Aging Cell, 2022, v. 21, n. 2, p. 1, doi. 10.1111/acel.13549

By:

Gomez-Suaga, Patricia;
Mórotz, Gábor M.;
Markovinovic, Andrea;
Martín-Guerrero, Sandra M.;
Preza, Elisavet;
Arias, Natalia;
Mayl, Keith;
Aabdien, Afra;
Gesheva, Vesela;
Nishimura, Agnes;
Annibali, Ambra;
Younbok Lee;
Mitchell, Jacqueline C.;
Wray, Selina;
Shaw, Christopher;
Noble, Wendy;
Miller, Christopher C. J.

Publication type:

Article

The Impact of High-Fidelity Simulation on Nurse Anesthesia Students' Knowledge, Self-Con?dence, and Psychomotor Skills.

Published in:

AANA Journal, 2023, v. 91, n. 4, p. 279

By:

Aguirre, Priscilla;
Amos, Veronica Y.;
Mitchell, Jacqueline C.

Publication type:

Article

ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43.

Published in:

Nature Communications, 2014, v. 5, n. 6, p. 3996, doi. 10.1038/ncomms4996

By:

Stoica, Radu;
De Vos, Kurt J.;
Paillusson, Sébastien;
Mueller, Sarah;
Sancho, Rosa M.;
Lau, Kwok-Fai;
Vizcay-Barrena, Gema;
Lin, Wen-Lang;
Xu, Ya-Fei;
Lewis, Jada;
Dickson, Dennis W.;
Petrucelli, Leonard;
Mitchell, Jacqueline C.;
Shaw, Christopher E.;
Miller, Christopher C. J.

Publication type:

Article

Expression of the neuronal adaptor protein X11alpha protects against memory dysfunction in a transgenic mouse model of Alzheimer's disease.

Published in:

2010

By:

Mitchell JC;
Perkinton MS;
Yates DM;
Lau KF;
Rogelj B;
Miller CC;
McLoughlin DM;
Mitchell, Jacqueline C;
Perkinton, Michael S;
Yates, Darran M;
Lau, Kwok-Fai;
Rogelj, Boris;
Miller, Christopher C J;
McLoughlin, Declan M

Publication type:

journal article

Expression of the Neuronal Adaptor Protein X11α Protects Against Memory Dysfunction in a Transgenic Mouse Model of Alzheimer's Disease.

Published in:

Journal of Alzheimer's Disease, 2010, v. 20, n. 1, p. 31, doi. 10.3233/JAD-2010-1341

By:

Mitchell, Jacqueline C.;
Perkinton, Michael S.;
Yates, Darran M.;
Lau, Kwok-Fai;
Rogelj, Boris;
Miller, Christopher C. J.;
McLoughlin, Declan M.

Publication type:

Article

Tauopathy induced by low level expression of a human brain-derived tau fragment in mice is rescued by phenylbutyrate.

Published in:

2016

By:

Bondulich, Marie K.;
Tong Guo;
Meehan, Christopher;
Manion, John;
Martin, Teresa Rodriguez;
Mitchell, Jacqueline C.;
Hortobagyi, Tibor;
Yankova, Natalia;
Stygelbout, Virginie;
Brion, Jean-Pierre;
Noble, Wendy;
Hanger, Diane P.;
Guo, Tong;
Rodriguez Martin, Teresa

Publication type:

journal article

The heat shock response plays an important role in TDP-43 clearance: evidence for dysfunction in amyotrophic lateral sclerosis.

Published in:

2016

By:

Han-Jou Chen;
Mitchell, Jacqueline C.;
Novoselov, Sergey;
Miller, Jack;
Nishimura, Agnes L.;
Scotter, Emma L.;
Vance, Caroline A.;
Cheetham, Michael E.;
Shaw, Christopher E.;
Chen, Han-Jou

Publication type:

journal article

P1-058: The neuronal X11α adaptor protein improves cognitive function of Tg2576 (APPswe) mice

Published in:

2008

By:

Yates, Darran M.;
Mitchell, Jacqueline C.;
Ariff, Belall;
Stephenson, John;
Miller, Christopher C.J.;
McLoughlin, Declan M.

Publication type:

Abstract

O4-02-04: The neuronal X11β adaptor protein improves cognitive and neuronal function in Tg2576 (APPswe) mice

Published in:

2008

By:

Mitchell, Jacqueline C.;
Yates, Darran M.;
Ariff, Belall;
Stephenson, John;
Miller, Christopher C.J.;
McLoughlin, Declan M.

Publication type:

Abstract

P1-382: Proteomic analysis of X11 interacting proteins

Published in:

2006

By:

Rogelj, Boris;
Mitchell, Jacqueline C.;
Lynham, Steven;
Byers, Helen L.;
Ward, Malcolm;
Miller, Christopher C.;
McLoughlin, Declan M.

Publication type:

Abstract

P1-054: The neuronal X11α adaptor protein improves cognitive function of Tg2576 (APPswe) mice

Published in:

2006

By:

Mitchell, Jacqueline C.;
Rogelj, Boris;
Ariff, Belall;
Sluyter, Frans;
Stephenson, John;
Miller, Christopher C.J.;
McLoughlin, Declan M.

Publication type:

Abstract

P1-382: Proteomic analysis of X11 interacting proteins

Published in:

2006

By:

Rogelj, Boris;
Mitchell, Jacqueline C.;
Lynham, Steven;
Byers, Helen L.;
Ward, Malcolm;
Miller, Christopher C.;
McLoughlin, Declan M.

Publication type:

Abstract

P1-054: The neuronal X11α adaptor protein improves cognitive function of Tg2576 (APPswe) mice

Published in:

2006

By:

Mitchell, Jacqueline C.;
Rogelj, Boris;
Ariff, Belall;
Sluyter, Frans;
Stephenson, John;
Miller, Christopher C.J.;
McLoughlin, Declan M.

Publication type:

Abstract

ALS/ FTD-associated FUS activates GSK-3β to disrupt the VAPB- PTPIP51 interaction and ER-mitochondria associations.

Published in:

EMBO Reports, 2016, v. 17, n. 9, p. 1326, doi. 10.15252/embr.201541726

By:

Stoica, Radu;
Paillusson, Sébastien;
Gomez‐Suaga, Patricia;
Mitchell, Jacqueline C;
Lau, Dawn HW;
Gray, Emma H;
Sancho, Rosa M;
Vizcay‐Barrena, Gema;
De Vos, Kurt J;
Shaw, Christopher E;
Hanger, Diane P;
Noble, Wendy;
Miller, Christopher CJ

Publication type:

Article

Mitochondrial abnormalities and disruption of the neuromuscular junction precede the clinical phenotype and motor neuron loss in hFUS<sup>WT</sup> transgenic mice.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 3, p. 463, doi. 10.1093/hmg/ddx415

By:

So, Eva;
Mitchell, Jacqueline C.;
Memmi, Caroline;
Chennell, George;
Vizcay-Barrena, Gema;
Allison, Leanne;
Shaw, Christopher E.;
Vance, Caroline

Publication type:

Article

ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules.

Published in:

Human Molecular Genetics, 2013, v. 22, n. 13, p. 2676, doi. 10.1093/hmg/ddt117

By:

Vance, Caroline;
Scotter, Emma L.;
Nishimura, Agnes L.;
Troakes, Claire;
Mitchell, Jacqueline C.;
Kathe, Claudia;
Urwin, Hazel;
Manser, Catherine;
Miller, Christopher C.;
Hortobágyi, Tibor;
Dragunow, Mike;
Rogelj, Boris;
Shaw, Christopher E.

Publication type:

Article

X11β rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice.

Published in:

Human Molecular Genetics, 2009, v. 18, n. 23, p. 4492, doi. 10.1093/hmg/ddp408

By:

Mitchell, Jacqueline C.;
Ariff, Belall B.;
Yates, Darran M.;
Lau, Kwok-Fai;
Perkinton, Michael S.;
Rogelj, Boris;
Stephenson, John D.;
Miller, Christopher C.J.;
McLoughlin, Declan M.

Publication type:

Article

Heterozygous expression of the Alzheimer’s disease-protective PLCγ2 P522R variant enhances Aβ clearance while preserving synapses.

Published in:

Cellular & Molecular Life Sciences, 2022, v. 79, n. 8, p. 1, doi. 10.1007/s00018-022-04473-1

By:

Solomon, Shiden;
Sampathkumar, Nirmal Kumar;
Carre, Ivo;
Mondal, Mrityunjoy;
Chennell, George;
Vernon, Anthony C.;
Ruepp, Marc-David;
Mitchell, Jacqueline C

Publication type:

Article